High-Throughput Microfluidic Production of Ultrasmall Lecithin Nanoliposomes for High-Efficacy Transdermal Delivery and Skin-Aging Treatment Article Swipe
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3390/biomedicines13020322
Background: Liposome particles with smaller sizes could increase transdermal drug delivery efficacy for enhanced skin penetration. While microfluidic methods have enabled controlled liposome synthesis, achieving efficient production of ultrasmall nanoliposomes (NLPUS) with a size smaller than 40 nm yet remains an unmet challenge. Methods: In this study, we employed a helical-blade-strengthened co-flow focusing (HBSCF) device to efficiently synthesize NLPUS, which demonstrated superior skin permeation and retention. Results: Liposome formulation primarily contains unsaturated lecithin, which endows an unprecedented capacity to NLPUS to scavenge reactive oxygen species (ROS). Moreover, NLPUS can effectively encapsulate a broad spectrum of anti-aging agents, including coenzyme Q10 (CoQ10), while preserving its physical properties. In a photoaged skin model, topical application of CoQ10-loaded NLPUS (CoQ10@NLPUS) inhibited ultraviolet B (UVB)-induced matrix metalloproteinase-1 (MMP-1) production, and promoted collagen type I (Col-I) synthesis in skin cells, thereby effectively rejuvenating the photoaged skin. Conclusions: This study presents a straightforward and efficient method for the production of NLPUS, thereby offering a promising platform for transdermal delivery of diverse therapeutic agents.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/biomedicines13020322
- OA Status
- gold
- Cited By
- 3
- References
- 44
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4406985433
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4406985433Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.3390/biomedicines13020322Digital Object Identifier
- Title
-
High-Throughput Microfluidic Production of Ultrasmall Lecithin Nanoliposomes for High-Efficacy Transdermal Delivery and Skin-Aging TreatmentWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-01-30Full publication date if available
- Authors
-
Xiao Hua Liang, Changli Lü, Fangqiao Zheng, Zhengyi Lan, Haoji Wang, Muhammad Shafiq, Xinxin Pan, Hangrong Chen, Ming MaList of authors in order
- Landing page
-
https://doi.org/10.3390/biomedicines13020322Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.3390/biomedicines13020322Direct OA link when available
- Concepts
-
Transdermal, Liposome, Lecithin, Photoaging, Chemistry, Drug delivery, Skin Aging, Biomedical engineering, Nanotechnology, Materials science, Pharmacology, Dermatology, Medicine, ChromatographyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
3Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 3Per-year citation counts (last 5 years)
- References (count)
-
44Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4406985433 |
|---|---|
| doi | https://doi.org/10.3390/biomedicines13020322 |
| ids.doi | https://doi.org/10.3390/biomedicines13020322 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/40002735 |
| ids.openalex | https://openalex.org/W4406985433 |
| fwci | 8.02650695 |
| type | article |
| title | High-Throughput Microfluidic Production of Ultrasmall Lecithin Nanoliposomes for High-Efficacy Transdermal Delivery and Skin-Aging Treatment |
| biblio.issue | 2 |
| biblio.volume | 13 |
| biblio.last_page | 322 |
| biblio.first_page | 322 |
| grants[0].funder | https://openalex.org/F4320321001 |
| grants[0].award_id | 52072392 |
| grants[0].funder_display_name | National Natural Science Foundation of China |
| grants[1].funder | https://openalex.org/F4320321001 |
| grants[1].award_id | 52472290 |
| grants[1].funder_display_name | National Natural Science Foundation of China |
| grants[2].funder | https://openalex.org/F4320322847 |
| grants[2].award_id | 2020255 |
| grants[2].funder_display_name | Youth Innovation Promotion Association of the Chinese Academy of Sciences |
| topics[0].id | https://openalex.org/T10704 |
| topics[0].field.id | https://openalex.org/fields/30 |
| topics[0].field.display_name | Pharmacology, Toxicology and Pharmaceutics |
| topics[0].score | 0.9988999962806702 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/3003 |
| topics[0].subfield.display_name | Pharmaceutical Science |
| topics[0].display_name | Advancements in Transdermal Drug Delivery |
| topics[1].id | https://openalex.org/T11013 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9930999875068665 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2708 |
| topics[1].subfield.display_name | Dermatology |
| topics[1].display_name | Skin Protection and Aging |
| topics[2].id | https://openalex.org/T12856 |
| topics[2].field.id | https://openalex.org/fields/13 |
| topics[2].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[2].score | 0.970300018787384 |
| topics[2].domain.id | https://openalex.org/domains/1 |
| topics[2].domain.display_name | Life Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/1305 |
| topics[2].subfield.display_name | Biotechnology |
| topics[2].display_name | Transgenic Plants and Applications |
| funders[0].id | https://openalex.org/F4320321001 |
| funders[0].ror | https://ror.org/01h0zpd94 |
| funders[0].display_name | National Natural Science Foundation of China |
| funders[1].id | https://openalex.org/F4320322847 |
| funders[1].ror | https://ror.org/031141b54 |
| funders[1].display_name | Youth Innovation Promotion Association of the Chinese Academy of Sciences |
| is_xpac | False |
| apc_list.value | 2200 |
| apc_list.currency | CHF |
| apc_list.value_usd | 2382 |
| apc_paid.value | 2200 |
| apc_paid.currency | CHF |
| apc_paid.value_usd | 2382 |
| concepts[0].id | https://openalex.org/C205679159 |
| concepts[0].level | 2 |
| concepts[0].score | 0.8462489247322083 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q3375179 |
| concepts[0].display_name | Transdermal |
| concepts[1].id | https://openalex.org/C185154212 |
| concepts[1].level | 2 |
| concepts[1].score | 0.7203851342201233 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q410454 |
| concepts[1].display_name | Liposome |
| concepts[2].id | https://openalex.org/C2779564620 |
| concepts[2].level | 2 |
| concepts[2].score | 0.6255247592926025 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q241595 |
| concepts[2].display_name | Lecithin |
| concepts[3].id | https://openalex.org/C2776960578 |
| concepts[3].level | 2 |
| concepts[3].score | 0.6182374358177185 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q3705873 |
| concepts[3].display_name | Photoaging |
| concepts[4].id | https://openalex.org/C185592680 |
| concepts[4].level | 0 |
| concepts[4].score | 0.47983166575431824 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q2329 |
| concepts[4].display_name | Chemistry |
| concepts[5].id | https://openalex.org/C2779820397 |
| concepts[5].level | 2 |
| concepts[5].score | 0.4797405004501343 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q1392806 |
| concepts[5].display_name | Drug delivery |
| concepts[6].id | https://openalex.org/C2909910311 |
| concepts[6].level | 2 |
| concepts[6].score | 0.46294084191322327 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q5259911 |
| concepts[6].display_name | Skin Aging |
| concepts[7].id | https://openalex.org/C136229726 |
| concepts[7].level | 1 |
| concepts[7].score | 0.4510308504104614 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q327092 |
| concepts[7].display_name | Biomedical engineering |
| concepts[8].id | https://openalex.org/C171250308 |
| concepts[8].level | 1 |
| concepts[8].score | 0.34843897819519043 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q11468 |
| concepts[8].display_name | Nanotechnology |
| concepts[9].id | https://openalex.org/C192562407 |
| concepts[9].level | 0 |
| concepts[9].score | 0.34176871180534363 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q228736 |
| concepts[9].display_name | Materials science |
| concepts[10].id | https://openalex.org/C98274493 |
| concepts[10].level | 1 |
| concepts[10].score | 0.3175659775733948 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q128406 |
| concepts[10].display_name | Pharmacology |
| concepts[11].id | https://openalex.org/C16005928 |
| concepts[11].level | 1 |
| concepts[11].score | 0.16620159149169922 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q171171 |
| concepts[11].display_name | Dermatology |
| concepts[12].id | https://openalex.org/C71924100 |
| concepts[12].level | 0 |
| concepts[12].score | 0.15309566259384155 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[12].display_name | Medicine |
| concepts[13].id | https://openalex.org/C43617362 |
| concepts[13].level | 1 |
| concepts[13].score | 0.12005925178527832 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q170050 |
| concepts[13].display_name | Chromatography |
| keywords[0].id | https://openalex.org/keywords/transdermal |
| keywords[0].score | 0.8462489247322083 |
| keywords[0].display_name | Transdermal |
| keywords[1].id | https://openalex.org/keywords/liposome |
| keywords[1].score | 0.7203851342201233 |
| keywords[1].display_name | Liposome |
| keywords[2].id | https://openalex.org/keywords/lecithin |
| keywords[2].score | 0.6255247592926025 |
| keywords[2].display_name | Lecithin |
| keywords[3].id | https://openalex.org/keywords/photoaging |
| keywords[3].score | 0.6182374358177185 |
| keywords[3].display_name | Photoaging |
| keywords[4].id | https://openalex.org/keywords/chemistry |
| keywords[4].score | 0.47983166575431824 |
| keywords[4].display_name | Chemistry |
| keywords[5].id | https://openalex.org/keywords/drug-delivery |
| keywords[5].score | 0.4797405004501343 |
| keywords[5].display_name | Drug delivery |
| keywords[6].id | https://openalex.org/keywords/skin-aging |
| keywords[6].score | 0.46294084191322327 |
| keywords[6].display_name | Skin Aging |
| keywords[7].id | https://openalex.org/keywords/biomedical-engineering |
| keywords[7].score | 0.4510308504104614 |
| keywords[7].display_name | Biomedical engineering |
| keywords[8].id | https://openalex.org/keywords/nanotechnology |
| keywords[8].score | 0.34843897819519043 |
| keywords[8].display_name | Nanotechnology |
| keywords[9].id | https://openalex.org/keywords/materials-science |
| keywords[9].score | 0.34176871180534363 |
| keywords[9].display_name | Materials science |
| keywords[10].id | https://openalex.org/keywords/pharmacology |
| keywords[10].score | 0.3175659775733948 |
| keywords[10].display_name | Pharmacology |
| keywords[11].id | https://openalex.org/keywords/dermatology |
| keywords[11].score | 0.16620159149169922 |
| keywords[11].display_name | Dermatology |
| keywords[12].id | https://openalex.org/keywords/medicine |
| keywords[12].score | 0.15309566259384155 |
| keywords[12].display_name | Medicine |
| keywords[13].id | https://openalex.org/keywords/chromatography |
| keywords[13].score | 0.12005925178527832 |
| keywords[13].display_name | Chromatography |
| language | en |
| locations[0].id | doi:10.3390/biomedicines13020322 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S2737005842 |
| locations[0].source.issn | 2227-9059 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 2227-9059 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Biomedicines |
| locations[0].source.host_organization | https://openalex.org/P4310310987 |
| locations[0].source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310310987 |
| locations[0].license | cc-by |
| locations[0].pdf_url | |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Biomedicines |
| locations[0].landing_page_url | https://doi.org/10.3390/biomedicines13020322 |
| locations[1].id | pmid:40002735 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Biomedicines |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/40002735 |
| locations[2].id | pmh:oai:pubmedcentral.nih.gov:11853437 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S2764455111 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | PubMed Central |
| locations[2].source.host_organization | https://openalex.org/I1299303238 |
| locations[2].source.host_organization_name | National Institutes of Health |
| locations[2].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[2].license | other-oa |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | https://openalex.org/licenses/other-oa |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Biomedicines |
| locations[2].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/11853437 |
| locations[3].id | pmh:oai:doaj.org/article:2c2f5e9d42554a42aac75fee0e143f9d |
| locations[3].is_oa | False |
| locations[3].source.id | https://openalex.org/S4306401280 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[3].source.host_organization | |
| locations[3].source.host_organization_name | |
| locations[3].source.host_organization_lineage | |
| locations[3].license | |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | article |
| locations[3].license_id | |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | Biomedicines, Vol 13, Iss 2, p 322 (2025) |
| locations[3].landing_page_url | https://doaj.org/article/2c2f5e9d42554a42aac75fee0e143f9d |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5102334404 |
| authorships[0].author.orcid | https://orcid.org/0009-0004-4046-5360 |
| authorships[0].author.display_name | Xiao Hua Liang |
| authorships[0].countries | CN |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I4210165038 |
| authorships[0].affiliations[0].raw_affiliation_string | School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China |
| authorships[0].affiliations[1].institution_ids | https://openalex.org/I19820366, https://openalex.org/I4210163874 |
| authorships[0].affiliations[1].raw_affiliation_string | State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China |
| authorships[0].institutions[0].id | https://openalex.org/I19820366 |
| authorships[0].institutions[0].ror | https://ror.org/034t30j35 |
| authorships[0].institutions[0].type | government |
| authorships[0].institutions[0].lineage | https://openalex.org/I19820366 |
| authorships[0].institutions[0].country_code | CN |
| authorships[0].institutions[0].display_name | Chinese Academy of Sciences |
| authorships[0].institutions[1].id | https://openalex.org/I4210163874 |
| authorships[0].institutions[1].ror | https://ror.org/05etnz140 |
| authorships[0].institutions[1].type | facility |
| authorships[0].institutions[1].lineage | https://openalex.org/I19820366, https://openalex.org/I4210163874 |
| authorships[0].institutions[1].country_code | CN |
| authorships[0].institutions[1].display_name | Shanghai Institute of Ceramics |
| authorships[0].institutions[2].id | https://openalex.org/I4210165038 |
| authorships[0].institutions[2].ror | https://ror.org/05qbk4x57 |
| authorships[0].institutions[2].type | education |
| authorships[0].institutions[2].lineage | https://openalex.org/I19820366, https://openalex.org/I4210165038 |
| authorships[0].institutions[2].country_code | CN |
| authorships[0].institutions[2].display_name | University of Chinese Academy of Sciences |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Xiao Liang |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China, State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China |
| authorships[1].author.id | https://openalex.org/A5088824582 |
| authorships[1].author.orcid | https://orcid.org/0000-0003-1978-0628 |
| authorships[1].author.display_name | Changli Lü |
| authorships[1].countries | CN |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I19820366, https://openalex.org/I4210163874 |
| authorships[1].affiliations[0].raw_affiliation_string | State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China |
| authorships[1].affiliations[1].institution_ids | https://openalex.org/I4210165038 |
| authorships[1].affiliations[1].raw_affiliation_string | School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China |
| authorships[1].institutions[0].id | https://openalex.org/I19820366 |
| authorships[1].institutions[0].ror | https://ror.org/034t30j35 |
| authorships[1].institutions[0].type | government |
| authorships[1].institutions[0].lineage | https://openalex.org/I19820366 |
| authorships[1].institutions[0].country_code | CN |
| authorships[1].institutions[0].display_name | Chinese Academy of Sciences |
| authorships[1].institutions[1].id | https://openalex.org/I4210163874 |
| authorships[1].institutions[1].ror | https://ror.org/05etnz140 |
| authorships[1].institutions[1].type | facility |
| authorships[1].institutions[1].lineage | https://openalex.org/I19820366, https://openalex.org/I4210163874 |
| authorships[1].institutions[1].country_code | CN |
| authorships[1].institutions[1].display_name | Shanghai Institute of Ceramics |
| authorships[1].institutions[2].id | https://openalex.org/I4210165038 |
| authorships[1].institutions[2].ror | https://ror.org/05qbk4x57 |
| authorships[1].institutions[2].type | education |
| authorships[1].institutions[2].lineage | https://openalex.org/I19820366, https://openalex.org/I4210165038 |
| authorships[1].institutions[2].country_code | CN |
| authorships[1].institutions[2].display_name | University of Chinese Academy of Sciences |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Chan Lu |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China, State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China |
| authorships[2].author.id | https://openalex.org/A5101380797 |
| authorships[2].author.orcid | |
| authorships[2].author.display_name | Fangqiao Zheng |
| authorships[2].countries | CN |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I19820366, https://openalex.org/I4210163874 |
| authorships[2].affiliations[0].raw_affiliation_string | State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China |
| authorships[2].affiliations[1].institution_ids | https://openalex.org/I4210165038 |
| authorships[2].affiliations[1].raw_affiliation_string | School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China |
| authorships[2].institutions[0].id | https://openalex.org/I19820366 |
| authorships[2].institutions[0].ror | https://ror.org/034t30j35 |
| authorships[2].institutions[0].type | government |
| authorships[2].institutions[0].lineage | https://openalex.org/I19820366 |
| authorships[2].institutions[0].country_code | CN |
| authorships[2].institutions[0].display_name | Chinese Academy of Sciences |
| authorships[2].institutions[1].id | https://openalex.org/I4210163874 |
| authorships[2].institutions[1].ror | https://ror.org/05etnz140 |
| authorships[2].institutions[1].type | facility |
| authorships[2].institutions[1].lineage | https://openalex.org/I19820366, https://openalex.org/I4210163874 |
| authorships[2].institutions[1].country_code | CN |
| authorships[2].institutions[1].display_name | Shanghai Institute of Ceramics |
| authorships[2].institutions[2].id | https://openalex.org/I4210165038 |
| authorships[2].institutions[2].ror | https://ror.org/05qbk4x57 |
| authorships[2].institutions[2].type | education |
| authorships[2].institutions[2].lineage | https://openalex.org/I19820366, https://openalex.org/I4210165038 |
| authorships[2].institutions[2].country_code | CN |
| authorships[2].institutions[2].display_name | University of Chinese Academy of Sciences |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Fangqiao Zheng |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China, State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China |
| authorships[3].author.id | https://openalex.org/A5085814776 |
| authorships[3].author.orcid | |
| authorships[3].author.display_name | Zhengyi Lan |
| authorships[3].countries | CN |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I19820366, https://openalex.org/I4210163874 |
| authorships[3].affiliations[0].raw_affiliation_string | State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China |
| authorships[3].institutions[0].id | https://openalex.org/I19820366 |
| authorships[3].institutions[0].ror | https://ror.org/034t30j35 |
| authorships[3].institutions[0].type | government |
| authorships[3].institutions[0].lineage | https://openalex.org/I19820366 |
| authorships[3].institutions[0].country_code | CN |
| authorships[3].institutions[0].display_name | Chinese Academy of Sciences |
| authorships[3].institutions[1].id | https://openalex.org/I4210163874 |
| authorships[3].institutions[1].ror | https://ror.org/05etnz140 |
| authorships[3].institutions[1].type | facility |
| authorships[3].institutions[1].lineage | https://openalex.org/I19820366, https://openalex.org/I4210163874 |
| authorships[3].institutions[1].country_code | CN |
| authorships[3].institutions[1].display_name | Shanghai Institute of Ceramics |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Zhengyi Lan |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China |
| authorships[4].author.id | https://openalex.org/A5048320823 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-7707-0088 |
| authorships[4].author.display_name | Haoji Wang |
| authorships[4].countries | CN |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I19820366, https://openalex.org/I4210163874 |
| authorships[4].affiliations[0].raw_affiliation_string | State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China |
| authorships[4].affiliations[1].institution_ids | https://openalex.org/I4210165038 |
| authorships[4].affiliations[1].raw_affiliation_string | School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China |
| authorships[4].institutions[0].id | https://openalex.org/I19820366 |
| authorships[4].institutions[0].ror | https://ror.org/034t30j35 |
| authorships[4].institutions[0].type | government |
| authorships[4].institutions[0].lineage | https://openalex.org/I19820366 |
| authorships[4].institutions[0].country_code | CN |
| authorships[4].institutions[0].display_name | Chinese Academy of Sciences |
| authorships[4].institutions[1].id | https://openalex.org/I4210163874 |
| authorships[4].institutions[1].ror | https://ror.org/05etnz140 |
| authorships[4].institutions[1].type | facility |
| authorships[4].institutions[1].lineage | https://openalex.org/I19820366, https://openalex.org/I4210163874 |
| authorships[4].institutions[1].country_code | CN |
| authorships[4].institutions[1].display_name | Shanghai Institute of Ceramics |
| authorships[4].institutions[2].id | https://openalex.org/I4210165038 |
| authorships[4].institutions[2].ror | https://ror.org/05qbk4x57 |
| authorships[4].institutions[2].type | education |
| authorships[4].institutions[2].lineage | https://openalex.org/I19820366, https://openalex.org/I4210165038 |
| authorships[4].institutions[2].country_code | CN |
| authorships[4].institutions[2].display_name | University of Chinese Academy of Sciences |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Haoji Wang |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China, State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China |
| authorships[5].author.id | https://openalex.org/A5100771198 |
| authorships[5].author.orcid | https://orcid.org/0000-0002-5887-5032 |
| authorships[5].author.display_name | Muhammad Shafiq |
| authorships[5].countries | JP |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I4210087333 |
| authorships[5].affiliations[0].raw_affiliation_string | Innovation Center of NanoMedicine (iCONM), Kawasaki Institute of Industrial Promotion, Kawasaki-ku, Kawasaki 210-0821, Japan |
| authorships[5].institutions[0].id | https://openalex.org/I4210087333 |
| authorships[5].institutions[0].ror | https://ror.org/000j6sc87 |
| authorships[5].institutions[0].type | healthcare |
| authorships[5].institutions[0].lineage | https://openalex.org/I4210087333 |
| authorships[5].institutions[0].country_code | JP |
| authorships[5].institutions[0].display_name | Innovation Center of NanoMedicine |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Muhammad Shafiq |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Innovation Center of NanoMedicine (iCONM), Kawasaki Institute of Industrial Promotion, Kawasaki-ku, Kawasaki 210-0821, Japan |
| authorships[6].author.id | https://openalex.org/A5100549666 |
| authorships[6].author.orcid | |
| authorships[6].author.display_name | Xinxin Pan |
| authorships[6].countries | CN |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I143593769 |
| authorships[6].affiliations[0].raw_affiliation_string | School of Biotechnology, East China University of Science and Technology, Shanghai 200237, China |
| authorships[6].institutions[0].id | https://openalex.org/I143593769 |
| authorships[6].institutions[0].ror | https://ror.org/01vyrm377 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I143593769 |
| authorships[6].institutions[0].country_code | CN |
| authorships[6].institutions[0].display_name | East China University of Science and Technology |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Xinxin Pan |
| authorships[6].is_corresponding | True |
| authorships[6].raw_affiliation_strings | School of Biotechnology, East China University of Science and Technology, Shanghai 200237, China |
| authorships[7].author.id | https://openalex.org/A5013084576 |
| authorships[7].author.orcid | https://orcid.org/0000-0003-0827-1270 |
| authorships[7].author.display_name | Hangrong Chen |
| authorships[7].countries | CN |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I4210165038 |
| authorships[7].affiliations[0].raw_affiliation_string | School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China |
| authorships[7].affiliations[1].institution_ids | https://openalex.org/I19820366, https://openalex.org/I4210163874 |
| authorships[7].affiliations[1].raw_affiliation_string | State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China |
| authorships[7].institutions[0].id | https://openalex.org/I19820366 |
| authorships[7].institutions[0].ror | https://ror.org/034t30j35 |
| authorships[7].institutions[0].type | government |
| authorships[7].institutions[0].lineage | https://openalex.org/I19820366 |
| authorships[7].institutions[0].country_code | CN |
| authorships[7].institutions[0].display_name | Chinese Academy of Sciences |
| authorships[7].institutions[1].id | https://openalex.org/I4210163874 |
| authorships[7].institutions[1].ror | https://ror.org/05etnz140 |
| authorships[7].institutions[1].type | facility |
| authorships[7].institutions[1].lineage | https://openalex.org/I19820366, https://openalex.org/I4210163874 |
| authorships[7].institutions[1].country_code | CN |
| authorships[7].institutions[1].display_name | Shanghai Institute of Ceramics |
| authorships[7].institutions[2].id | https://openalex.org/I4210165038 |
| authorships[7].institutions[2].ror | https://ror.org/05qbk4x57 |
| authorships[7].institutions[2].type | education |
| authorships[7].institutions[2].lineage | https://openalex.org/I19820366, https://openalex.org/I4210165038 |
| authorships[7].institutions[2].country_code | CN |
| authorships[7].institutions[2].display_name | University of Chinese Academy of Sciences |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Hangrong Chen |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China, State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China |
| authorships[8].author.id | https://openalex.org/A5025620514 |
| authorships[8].author.orcid | https://orcid.org/0000-0002-1068-4528 |
| authorships[8].author.display_name | Ming Ma |
| authorships[8].countries | CN |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I4210165038 |
| authorships[8].affiliations[0].raw_affiliation_string | School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China |
| authorships[8].affiliations[1].institution_ids | https://openalex.org/I19820366, https://openalex.org/I4210163874 |
| authorships[8].affiliations[1].raw_affiliation_string | State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China |
| authorships[8].institutions[0].id | https://openalex.org/I19820366 |
| authorships[8].institutions[0].ror | https://ror.org/034t30j35 |
| authorships[8].institutions[0].type | government |
| authorships[8].institutions[0].lineage | https://openalex.org/I19820366 |
| authorships[8].institutions[0].country_code | CN |
| authorships[8].institutions[0].display_name | Chinese Academy of Sciences |
| authorships[8].institutions[1].id | https://openalex.org/I4210163874 |
| authorships[8].institutions[1].ror | https://ror.org/05etnz140 |
| authorships[8].institutions[1].type | facility |
| authorships[8].institutions[1].lineage | https://openalex.org/I19820366, https://openalex.org/I4210163874 |
| authorships[8].institutions[1].country_code | CN |
| authorships[8].institutions[1].display_name | Shanghai Institute of Ceramics |
| authorships[8].institutions[2].id | https://openalex.org/I4210165038 |
| authorships[8].institutions[2].ror | https://ror.org/05qbk4x57 |
| authorships[8].institutions[2].type | education |
| authorships[8].institutions[2].lineage | https://openalex.org/I19820366, https://openalex.org/I4210165038 |
| authorships[8].institutions[2].country_code | CN |
| authorships[8].institutions[2].display_name | University of Chinese Academy of Sciences |
| authorships[8].author_position | last |
| authorships[8].raw_author_name | Ming Ma |
| authorships[8].is_corresponding | True |
| authorships[8].raw_affiliation_strings | School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China, State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://doi.org/10.3390/biomedicines13020322 |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | High-Throughput Microfluidic Production of Ultrasmall Lecithin Nanoliposomes for High-Efficacy Transdermal Delivery and Skin-Aging Treatment |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10704 |
| primary_topic.field.id | https://openalex.org/fields/30 |
| primary_topic.field.display_name | Pharmacology, Toxicology and Pharmaceutics |
| primary_topic.score | 0.9988999962806702 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/3003 |
| primary_topic.subfield.display_name | Pharmaceutical Science |
| primary_topic.display_name | Advancements in Transdermal Drug Delivery |
| related_works | https://openalex.org/W2743016687, https://openalex.org/W1533187718, https://openalex.org/W1994972521, https://openalex.org/W2394699721, https://openalex.org/W4390446390, https://openalex.org/W2153657435, https://openalex.org/W2970461785, https://openalex.org/W2108550755, https://openalex.org/W115872829, https://openalex.org/W2187436478 |
| cited_by_count | 3 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 3 |
| locations_count | 4 |
| best_oa_location.id | doi:10.3390/biomedicines13020322 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2737005842 |
| best_oa_location.source.issn | 2227-9059 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 2227-9059 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Biomedicines |
| best_oa_location.source.host_organization | https://openalex.org/P4310310987 |
| best_oa_location.source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310310987 |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Biomedicines |
| best_oa_location.landing_page_url | https://doi.org/10.3390/biomedicines13020322 |
| primary_location.id | doi:10.3390/biomedicines13020322 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S2737005842 |
| primary_location.source.issn | 2227-9059 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 2227-9059 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Biomedicines |
| primary_location.source.host_organization | https://openalex.org/P4310310987 |
| primary_location.source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310310987 |
| primary_location.license | cc-by |
| primary_location.pdf_url | |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Biomedicines |
| primary_location.landing_page_url | https://doi.org/10.3390/biomedicines13020322 |
| publication_date | 2025-01-30 |
| publication_year | 2025 |
| referenced_works | https://openalex.org/W3141040296, https://openalex.org/W2909026612, https://openalex.org/W3211489143, https://openalex.org/W1979316087, https://openalex.org/W2242840047, https://openalex.org/W3206841455, https://openalex.org/W3207589655, https://openalex.org/W2100389865, https://openalex.org/W4396776436, https://openalex.org/W2009426872, https://openalex.org/W3096990329, https://openalex.org/W3177112762, https://openalex.org/W6842489148, https://openalex.org/W4291017615, https://openalex.org/W4220983043, https://openalex.org/W4361276120, https://openalex.org/W4327972600, https://openalex.org/W4220926015, https://openalex.org/W2896167065, https://openalex.org/W2884445981, https://openalex.org/W4401027377, https://openalex.org/W4388562436, https://openalex.org/W2070336138, https://openalex.org/W2138553063, https://openalex.org/W3201239328, https://openalex.org/W2942900492, https://openalex.org/W2049075059, https://openalex.org/W2012196034, https://openalex.org/W2149744058, https://openalex.org/W4253648145, https://openalex.org/W4309471620, https://openalex.org/W4320843494, https://openalex.org/W4310433443, https://openalex.org/W4396820801, https://openalex.org/W2902912836, https://openalex.org/W4399972197, https://openalex.org/W2744693990, https://openalex.org/W2792148145, https://openalex.org/W3204512458, https://openalex.org/W2952827414, https://openalex.org/W2071419221, https://openalex.org/W2008820810, https://openalex.org/W4381857241, https://openalex.org/W4294733089 |
| referenced_works_count | 44 |
| abstract_inverted_index.B | 119 |
| abstract_inverted_index.I | 129 |
| abstract_inverted_index.a | 32, 49, 91, 107, 145, 157 |
| abstract_inverted_index.40 | 36 |
| abstract_inverted_index.In | 44, 106 |
| abstract_inverted_index.an | 40, 75 |
| abstract_inverted_index.in | 132 |
| abstract_inverted_index.nm | 37 |
| abstract_inverted_index.of | 27, 94, 113, 153, 163 |
| abstract_inverted_index.to | 55, 78, 80 |
| abstract_inverted_index.we | 47 |
| abstract_inverted_index.Q10 | 99 |
| abstract_inverted_index.and | 64, 125, 147 |
| abstract_inverted_index.can | 88 |
| abstract_inverted_index.for | 12, 150, 160 |
| abstract_inverted_index.its | 103 |
| abstract_inverted_index.the | 138, 151 |
| abstract_inverted_index.yet | 38 |
| abstract_inverted_index.This | 142 |
| abstract_inverted_index.drug | 9 |
| abstract_inverted_index.have | 19 |
| abstract_inverted_index.size | 33 |
| abstract_inverted_index.skin | 14, 62, 109, 133 |
| abstract_inverted_index.than | 35 |
| abstract_inverted_index.this | 45 |
| abstract_inverted_index.type | 128 |
| abstract_inverted_index.with | 3, 31 |
| abstract_inverted_index.NLPUS | 79, 87, 115 |
| abstract_inverted_index.While | 16 |
| abstract_inverted_index.broad | 92 |
| abstract_inverted_index.could | 6 |
| abstract_inverted_index.sizes | 5 |
| abstract_inverted_index.skin. | 140 |
| abstract_inverted_index.study | 143 |
| abstract_inverted_index.unmet | 41 |
| abstract_inverted_index.which | 59, 73 |
| abstract_inverted_index.while | 101 |
| abstract_inverted_index.(ROS). | 85 |
| abstract_inverted_index.NLPUS, | 58, 154 |
| abstract_inverted_index.cells, | 134 |
| abstract_inverted_index.device | 54 |
| abstract_inverted_index.endows | 74 |
| abstract_inverted_index.matrix | 121 |
| abstract_inverted_index.method | 149 |
| abstract_inverted_index.model, | 110 |
| abstract_inverted_index.oxygen | 83 |
| abstract_inverted_index.study, | 46 |
| abstract_inverted_index.(Col-I) | 130 |
| abstract_inverted_index.(HBSCF) | 53 |
| abstract_inverted_index.(MMP-1) | 123 |
| abstract_inverted_index.(NLPUS) | 30 |
| abstract_inverted_index.agents, | 96 |
| abstract_inverted_index.agents. | 166 |
| abstract_inverted_index.co-flow | 51 |
| abstract_inverted_index.diverse | 164 |
| abstract_inverted_index.enabled | 20 |
| abstract_inverted_index.methods | 18 |
| abstract_inverted_index.remains | 39 |
| abstract_inverted_index.smaller | 4, 34 |
| abstract_inverted_index.species | 84 |
| abstract_inverted_index.thereby | 135, 155 |
| abstract_inverted_index.topical | 111 |
| abstract_inverted_index.(CoQ10), | 100 |
| abstract_inverted_index.Liposome | 1, 67 |
| abstract_inverted_index.Methods: | 43 |
| abstract_inverted_index.Results: | 66 |
| abstract_inverted_index.capacity | 77 |
| abstract_inverted_index.coenzyme | 98 |
| abstract_inverted_index.collagen | 127 |
| abstract_inverted_index.contains | 70 |
| abstract_inverted_index.delivery | 10, 162 |
| abstract_inverted_index.efficacy | 11 |
| abstract_inverted_index.employed | 48 |
| abstract_inverted_index.enhanced | 13 |
| abstract_inverted_index.focusing | 52 |
| abstract_inverted_index.increase | 7 |
| abstract_inverted_index.liposome | 22 |
| abstract_inverted_index.offering | 156 |
| abstract_inverted_index.physical | 104 |
| abstract_inverted_index.platform | 159 |
| abstract_inverted_index.presents | 144 |
| abstract_inverted_index.promoted | 126 |
| abstract_inverted_index.reactive | 82 |
| abstract_inverted_index.scavenge | 81 |
| abstract_inverted_index.spectrum | 93 |
| abstract_inverted_index.superior | 61 |
| abstract_inverted_index.Moreover, | 86 |
| abstract_inverted_index.achieving | 24 |
| abstract_inverted_index.efficient | 25, 148 |
| abstract_inverted_index.including | 97 |
| abstract_inverted_index.inhibited | 117 |
| abstract_inverted_index.lecithin, | 72 |
| abstract_inverted_index.particles | 2 |
| abstract_inverted_index.photoaged | 108, 139 |
| abstract_inverted_index.primarily | 69 |
| abstract_inverted_index.promising | 158 |
| abstract_inverted_index.synthesis | 131 |
| abstract_inverted_index.anti-aging | 95 |
| abstract_inverted_index.challenge. | 42 |
| abstract_inverted_index.controlled | 21 |
| abstract_inverted_index.permeation | 63 |
| abstract_inverted_index.preserving | 102 |
| abstract_inverted_index.production | 26, 152 |
| abstract_inverted_index.retention. | 65 |
| abstract_inverted_index.synthesis, | 23 |
| abstract_inverted_index.synthesize | 57 |
| abstract_inverted_index.ultrasmall | 28 |
| abstract_inverted_index.Background: | 0 |
| abstract_inverted_index.application | 112 |
| abstract_inverted_index.effectively | 89, 136 |
| abstract_inverted_index.efficiently | 56 |
| abstract_inverted_index.encapsulate | 90 |
| abstract_inverted_index.formulation | 68 |
| abstract_inverted_index.production, | 124 |
| abstract_inverted_index.properties. | 105 |
| abstract_inverted_index.therapeutic | 165 |
| abstract_inverted_index.transdermal | 8, 161 |
| abstract_inverted_index.ultraviolet | 118 |
| abstract_inverted_index.unsaturated | 71 |
| abstract_inverted_index.CoQ10-loaded | 114 |
| abstract_inverted_index.Conclusions: | 141 |
| abstract_inverted_index.demonstrated | 60 |
| abstract_inverted_index.microfluidic | 17 |
| abstract_inverted_index.penetration. | 15 |
| abstract_inverted_index.rejuvenating | 137 |
| abstract_inverted_index.(CoQ10@NLPUS) | 116 |
| abstract_inverted_index.(UVB)-induced | 120 |
| abstract_inverted_index.nanoliposomes | 29 |
| abstract_inverted_index.unprecedented | 76 |
| abstract_inverted_index.straightforward | 146 |
| abstract_inverted_index.metalloproteinase-1 | 122 |
| abstract_inverted_index.helical-blade-strengthened | 50 |
| cited_by_percentile_year.max | 98 |
| cited_by_percentile_year.min | 97 |
| corresponding_author_ids | https://openalex.org/A5025620514, https://openalex.org/A5100549666 |
| countries_distinct_count | 2 |
| institutions_distinct_count | 9 |
| corresponding_institution_ids | https://openalex.org/I143593769, https://openalex.org/I19820366, https://openalex.org/I4210163874, https://openalex.org/I4210165038 |
| citation_normalized_percentile.value | 0.91986256 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |