High Transverse Relaxivity and Anticancer Agent Loading/Release Characteristics of Porous Calcium Phosphate Coated Iron Oxide Nanoparticles Article Swipe
Baharak Divband
,
Nahideh Gharehaghaji
,
Zahra Atashi
·
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.33263/briac113.1040210411
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.33263/briac113.1040210411
High relaxivity of MRI contrast agents leads to considerable contrast enhancement in the images and provides diagnostic accuracy. The purpose of the current study was to design a potential MRI contrast agent with a high relaxivity and investigate its curcumin loading/release property. To achieve this purpose, we synthesized the porous calcium phosphate coated iron oxide nanoparticles using a facile method and determined the physicochemical characteristics, cell compatibility effect, transverse relaxivity, and curcumin loading/release properties of the nanoparticles. The results indicated the spherical nanoparticles with a size of 10-20 nm. The nanoparticles demonstrated a superparamagnetic property and a high transverse relaxivity of 845.71 mM-1S-1. Although the porous calcium phosphate coated iron oxide nanoparticles were highly cytocompatible, the curcumin loaded nanoparticles showed a considerable effect on the bone marrow stem cells viability. In conclusion, the porous calcium phosphate coated iron oxide nanoparticles have the potential to introduce as a negative contrast agent of MRI with the ability of slow release of curcumin.
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- Type
- article
- Language
- en
- Landing Page
- http://doi.org/10.33263/briac113.1040210411
- https://doi.org/10.33263/briac113.1040210411
- OA Status
- diamond
- Cited By
- 4
- References
- 39
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4246974669
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4246974669Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.33263/briac113.1040210411Digital Object Identifier
- Title
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High Transverse Relaxivity and Anticancer Agent Loading/Release Characteristics of Porous Calcium Phosphate Coated Iron Oxide NanoparticlesWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2020Year of publication
- Publication date
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2020-10-26Full publication date if available
- Authors
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Baharak Divband, Nahideh Gharehaghaji, Zahra AtashiList of authors in order
- Landing page
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https://doi.org/10.33263/briac113.1040210411Publisher landing page
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https://doi.org/10.33263/briac113.1040210411Direct link to full text PDF
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YesWhether a free full text is available
- OA status
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diamondOpen access status per OpenAlex
- OA URL
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https://doi.org/10.33263/briac113.1040210411Direct OA link when available
- Concepts
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Nanoparticle, Iron oxide nanoparticles, Superparamagnetism, Calcium, MRI contrast agent, Iron oxide, Materials science, Porosity, Curcumin, Phosphate, Chemical engineering, Nanotechnology, Chemistry, Biochemistry, Composite material, Magnetization, Metallurgy, Magnetic field, Physics, Engineering, Quantum mechanicsTop concepts (fields/topics) attached by OpenAlex
- Cited by
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4Total citation count in OpenAlex
- Citations by year (recent)
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2022: 4Per-year citation counts (last 5 years)
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39Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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| referenced_works | https://openalex.org/W2900199803, https://openalex.org/W2922328088, https://openalex.org/W1995517062, https://openalex.org/W3016790576, https://openalex.org/W2082822489, https://openalex.org/W2319338089, https://openalex.org/W165024400, https://openalex.org/W2166198060, https://openalex.org/W2344801105, https://openalex.org/W2794142803, https://openalex.org/W2888033939, https://openalex.org/W3004045289, https://openalex.org/W2948731646, https://openalex.org/W2894459817, https://openalex.org/W2892158055, https://openalex.org/W2768995230, https://openalex.org/W3036440686, https://openalex.org/W2885092020, https://openalex.org/W2787246150, https://openalex.org/W3005267940, https://openalex.org/W2943240943, https://openalex.org/W2131641839, https://openalex.org/W2920953813, https://openalex.org/W2902144151, https://openalex.org/W3017210289, https://openalex.org/W3044687705, https://openalex.org/W2944503028, https://openalex.org/W2756019406, https://openalex.org/W2774240406, https://openalex.org/W2461225231, https://openalex.org/W2768857398, https://openalex.org/W1880795594, https://openalex.org/W2327225789, https://openalex.org/W2138485475, https://openalex.org/W3087495213, https://openalex.org/W2770362590, https://openalex.org/W2060029924, https://openalex.org/W2334467024, https://openalex.org/W3042577093 |
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