Histopathology-based protein multiplex generation using deep learning Article Swipe

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Sonali Andani , Boqi Chen , Joanna Ficek-Pascual , Simon Heinke , Ruben Casanova , Bernard Friedrich Hild , Bettina Sobottka , Bernd Bodenmiller , Ruedi Aebersold , Melike Ak , Faisal Alquaddoomi , Silvana I. Albert , Jonas Albinus , Ilaria Alborelli , Sonali Andani , Per-Olof Attinger , Marina Bacac , Daniel Baumhoer , Beatrice Beck‐Schimmer , Niko Beerenwinkel , Christian Beisel , Lara Bernasconi , Anne Bertolini , Bernd Bodenmiller , Ximena Bonilla , Lars Bosshard , Byron Calgua , Ruben Casanova , Stéphane Chevrier , Natalia Chicherova , Ricardo Coelho , Maya D’Costa , Esther Danenberg , Natalie R. Davidson , Monica-Andreea Baciu-Drăgan , Reinhard Dummer , Stefanie Engler , Martin Erkens , Katja Eschbach , Cinzia Esposito , André Fedier , Pedro Ferreira , Joanna Ficek-Pascual , Anja Frei , Bruno S. Frey , Sandra Goetze , Linda Grob , Gabriele Gut , Detlef Günther , Pirmin Haeuptle , Viola Heinzelmann‐Schwarz , Sylvia Herter , René Holtackers , Tamara Huesser , Alexander Immer , Anja Irmisch , Francis Jacob , Alice K. Jacobs , Tim M. Jaeger , Katharina Jahn , Alva Rani James , Philip Jermann , André Kahles , Abdullah Kahraman , Viktor H. Koelzer , Werner Kuebler , Jack Kuipers , Christian P. Kunze , Christian Kurzeder , Kjong-Van Lehmann , Mitchell P. Levesque , Ulrike Lischetti , Flavio C. Lombardo , Sebastian Lugert , Gerd Maass , Markus G. Manz , Philipp Markolin , Martin Mehnert , Julien Mena , Julian M. Metzler , Nicola Miglino , Emanuela S. Milani , H. Moch , Simone Muenst , Riccardo Murri , Charlotte K.Y. Ng , Stefan Nicolet , Marta Nowak , Mónica Núñez López , Patrick G. A. Pedrioli , Lucas Pelkmans , Salvatore Piscuoglio , Michael Prummer , Laurie Prélot , Natalie Rimmer , Mathilde Ritter , Christian Rommel , Mara L. Rosano-González , Gunnar Rätsch , Natascha Santacroce ·

YOU? · · 2025 · Open Access · · DOI: https://doi.org/10.1038/s42256-025-01074-y

Related Topics

Wavelength-Division Multiplexing

Computer Science

Artificial Intelligence

Pixel

Computational Biology

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Multiplex Computer science Digital pathology Tissue microarray Artificial intelligence Robustness (evolution) Pixel Computational biology Inference Pattern recognition (psychology) Machine learning Biology Bioinformatics Pathology Medicine Immunohistochemistry Gene Biochemistry

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Type: article
Language: en
Landing Page: https://doi.org/10.1038/s42256-025-01074-y
PDF: https://www.nature.com/articles/s42256-025-01074-y.pdf
OA Status: hybrid
References: 57
Related Works: 10
OpenAlex ID: https://openalex.org/W4412929290

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DOI: https://doi.org/10.1038/s42256-025-01074-y

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Title: Histopathology-based protein multiplex generation using deep learning

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Type: article

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Language: en

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Publication year: 2025

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Publication date: 2025-08-04

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Authors: Sonali Andani, Boqi Chen, Joanna Ficek-Pascual, Simon Heinke, Ruben Casanova, Bernard Friedrich Hild, Bettina Sobottka, Bernd Bodenmiller, Ruedi Aebersold, Melike Ak, Faisal Alquaddoomi, Silvana I. Albert, Jonas Albinus, Ilaria Alborelli, Sonali Andani, Per-Olof Attinger, Marina Bacac, Daniel Baumhoer, Beatrice Beck‐Schimmer, Niko Beerenwinkel, Christian Beisel, Lara Bernasconi, Anne Bertolini, Bernd Bodenmiller, Ximena Bonilla, Lars Bosshard, Byron Calgua, Ruben Casanova, Stéphane Chevrier, Natalia Chicherova, Ricardo Coelho, Maya D’Costa, Esther Danenberg, Natalie R. Davidson, Monica-Andreea Baciu-Drăgan, Reinhard Dummer, Stefanie Engler, Martin Erkens, Katja Eschbach, Cinzia Esposito, André Fedier, Pedro Ferreira, Joanna Ficek-Pascual, Anja Frei, Bruno S. Frey, Sandra Goetze, Linda Grob, Gabriele Gut, Detlef Günther, Pirmin Haeuptle, Viola Heinzelmann‐Schwarz, Sylvia Herter, René Holtackers, Tamara Huesser, Alexander Immer, Anja Irmisch, Francis Jacob, Alice K. Jacobs, Tim M. Jaeger, Katharina Jahn, Alva Rani James, Philip Jermann, André Kahles, Abdullah Kahraman, Viktor H. Koelzer, Werner Kuebler, Jack Kuipers, Christian P. Kunze, Christian Kurzeder, Kjong-Van Lehmann, Mitchell P. Levesque, Ulrike Lischetti, Flavio C. Lombardo, Sebastian Lugert, Gerd Maass, Markus G. Manz, Philipp Markolin, Martin Mehnert, Julien Mena, Julian M. Metzler, Nicola Miglino, Emanuela S. Milani, H. Moch, Simone Muenst, Riccardo Murri, Charlotte K.Y. Ng, Stefan Nicolet, Marta Nowak, Mónica Núñez López, Patrick G. A. Pedrioli, Lucas Pelkmans, Salvatore Piscuoglio, Michael Prummer, Laurie Prélot, Natalie Rimmer, Mathilde Ritter, Christian Rommel, Mara L. Rosano-González, Gunnar Rätsch, Natascha Santacroce

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Landing page: https://doi.org/10.1038/s42256-025-01074-y

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Concepts: Multiplex, Computer science, Digital pathology, Tissue microarray, Artificial intelligence, Robustness (evolution), Pixel, Computational biology, Inference, Pattern recognition (psychology), Machine learning, Biology, Bioinformatics, Pathology, Medicine, Immunohistochemistry, Gene, Biochemistry

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