Historical Insights and Current Perspectives on the Diagnosis and Management of Presymptomatic Type 1 Diabetes Article Swipe
KIMBER M. SIMMONS
,
Brigitte I. Frohnert
,
Holly K. O’Donnell
,
Kimberly Bautista
,
Cristy Geno Rasmussen
,
Andrea Gerard Gonzalez
,
Andrea K. Steck
,
Marian Rewers
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1089/dia.2023.0276
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1089/dia.2023.0276
Objective: The article provides practical guidance for (1) interpreting and confirming islet autoantibody screening results for type 1 diabetes (T1D) and (2) follow-up of individuals with early stages of T1D with the goal of ensuring medical safety and providing patients and their families with an assessment of risk for progression to a clinical diagnosis of T1D. Research Design and Methods: We used an explicit a priori methodology to identify areas of agreement and disagreement in how to manage patients with early T1D. We used a modified Delphi method, which is a systematic, iterative approach to identifying consensus. We developed a list of topic questions, ranked them by importance, and developed consensus statements based on available evidence and expert opinion around each of the 30 topic questions consistently ranked as being most important. Results: Consensus statements for screening and monitoring are supported with figures proposing an algorithm for confirmation of T1D diagnosis and management of early T1D until clinical diagnosis. Conclusions: Disseminating and increasing knowledge related to how to interpret T1D screening tests, confirm early T1D diagnosis and monitor for medical safety and clinical disease risk prediction is critically important as there are currently no clinical recommendations. Published guidance will promote better management of T1D screening-detected individuals.
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Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1089/dia.2023.0276
- OA Status
- hybrid
- Cited By
- 8
- References
- 69
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4386609925
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4386609925Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1089/dia.2023.0276Digital Object Identifier
- Title
-
Historical Insights and Current Perspectives on the Diagnosis and Management of Presymptomatic Type 1 DiabetesWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-09-11Full publication date if available
- Authors
-
KIMBER M. SIMMONS, Brigitte I. Frohnert, Holly K. O’Donnell, Kimberly Bautista, Cristy Geno Rasmussen, Andrea Gerard Gonzalez, Andrea K. Steck, Marian RewersList of authors in order
- Landing page
-
https://doi.org/10.1089/dia.2023.0276Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.1089/dia.2023.0276Direct OA link when available
- Concepts
-
Medicine, Delphi method, Type 1 diabetes, Disease, MEDLINE, Expert opinion, Intensive care medicine, Medical diagnosis, Diabetes mellitus, Pathology, Artificial intelligence, Computer science, Law, Endocrinology, Political scienceTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
8Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 5, 2024: 3Per-year citation counts (last 5 years)
- References (count)
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69Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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