How may Doppler indices help in the differentiation of obstructive from nonobstructive hydronephrosis? Article Swipe
Amir Hossein Sarrami
,
Maryam Riahinezhad
,
Alaleh Gheisari
,
Omid Shafaat
,
Alireza Merikhi
,
Mehdi Karami
,
Maryam Farghadani
,
Masoud Moslehi
·
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.4103/jrms.jrms_627_17
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.4103/jrms.jrms_627_17
Background: We assess the potency of different Doppler indices in the differentiation of obstructive and nonobstructive hydronephrosis. Materials and Methods: In this study, infants and children who were referred for the evaluation of unilateral hydronephrosis were enrolled. Ultrasonography for the assessment of the degree of hydronephrosis and a voiding cystourethrogram for the exclusion of vesicoureteral reflux was performed. Then, Doppler ultrasonography was done for both kidneys of each patient using four classic Doppler indices as well as the difference (delta) of each index between to kidneys. Diuretic renography with 99 mTc-ethylene dicysteine (99 mTc-EC) was performed for each patient. Results: Thirty-nine patients met the inclusion criteria. After diuretic renography, 29 (74.35%) patients had shown a nonobstructive pattern, and ten (25.65%) patients had a partial (intermediate) or complete obstruction. Using receiver operating characteristic (ROC) curve, none of the classic indices of Doppler duplex (i.e., resistive index [RI], resistance index, end diastolic velocity, and peak systolic velocity) had the ability to make a difference between obstructive and nonobstructive hydronephrosis. However, by calculating the difference (delta) of these indices between two kidneys of each patient, delta RI could differentiate the nonobstructive condition, significantly (P = 0.006). A cutoff value of 0.055 has 60% sensitivity and 82.8% specificity. The area under the ROC curve for delta RI is 0.795 (standard error: 0.086, 95% confidence interval [CI]: 0.626, 0.964). Furthermore, RI ratio between two kidneys of each patient could differentiate the nonobstructive condition, significantly (P = 0.012). A cutoff point of 1.075 has 70% sensitivity and 82.8% specificity. The area under the ROC curve for RI ratio was 0.769 (standard error: 0.104, 95% CI: 0.565, 0.973). Conclusion: This study shows that RI ratio and delta RI with a high specificity could differentiate nonobstructive hydronephrosis and therefore it is a promising way to use especially in the follow-up of children with hydronephrosis.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.4103/jrms.jrms_627_17
- OA Status
- gold
- Cited By
- 11
- References
- 32
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2888532072
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2888532072Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.4103/jrms.jrms_627_17Digital Object Identifier
- Title
-
How may Doppler indices help in the differentiation of obstructive from nonobstructive hydronephrosis?Work title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
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2018Year of publication
- Publication date
-
2018-01-01Full publication date if available
- Authors
-
Amir Hossein Sarrami, Maryam Riahinezhad, Alaleh Gheisari, Omid Shafaat, Alireza Merikhi, Mehdi Karami, Maryam Farghadani, Masoud MoslehiList of authors in order
- Landing page
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https://doi.org/10.4103/jrms.jrms_627_17Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
- OA URL
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https://doi.org/10.4103/jrms.jrms_627_17Direct OA link when available
- Concepts
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Medicine, Hydronephrosis, Doppler effect, Internal medicine, Urinary system, Astronomy, PhysicsTop concepts (fields/topics) attached by OpenAlex
- Cited by
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11Total citation count in OpenAlex
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2025: 1, 2024: 1, 2023: 3, 2022: 3, 2021: 1Per-year citation counts (last 5 years)
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10Other works algorithmically related by OpenAlex
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