Human iPSC-derived microglia carrying LRRK2-G2019 mutation show Parkinson's disease related transcriptional profile and functions Article Swipe

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Giudice Luca ·

YOU? · · 2027 · Open Access · · DOI: https://doi.org/10.5281/zenodo.7803014

This repository contains the data and the code used in Ohtone Sohvi's project. A folder can contain the starting raw data in "data", the R scripts in order of execution (op1, op2 ..) and the "output" folder that contains the final processed data of each operation. "PD_bulk_analysis" contains the processing and analysis of the bulk RNA sequencing data "PD_bulk_fastq" contains the raw fastq sequences of the bulk RNA sequencing "PD_bulk_nfcore" contains the results of processing the fasta sequences with nfcore rnaseq workflow "PD_scRNA_analysis" contains the analysis of the snRNA sequencing dataset "PD_spatial" contains the raw data of the spatial sequencing, the assempbly of the spatial expression profiles starting from the DAPI images and the transcripts coordinates, the analysis performed on the data

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LRRK2 Microglia Parkinson's disease Disease Mutation Biology Neuroscience Genetics Medicine Gene Immunology Internal medicine Inflammation

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Type: dataset
Language: en
Landing Page: https://doi.org/10.5281/zenodo.7803014
OA Status: green
Related Works: 10
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DOI: https://doi.org/10.5281/zenodo.7803014

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Title: Human iPSC-derived microglia carrying LRRK2-G2019 mutation show Parkinson's disease related transcriptional profile and functions

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Type: dataset

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Language: en

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Publication year: 2027

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Publication date: 2027-01-01

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Authors: Giudice Luca

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Landing page: https://doi.org/10.5281/zenodo.7803014

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Open access: Yes

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OA status: green

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OA URL: https://doi.org/10.5281/zenodo.7803014

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Concepts: LRRK2, Microglia, Parkinson's disease, Disease, Mutation, Biology, Neuroscience, Genetics, Medicine, Gene, Immunology, Internal medicine, Inflammation

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Cited by: 0

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Related works (count): 10

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