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Hypereosinophilia and Hypereosinophilic Syndromes: First Findings From a Nationwide Multicenter Cohort
January 2025 • Guillaume Lefèvre, S. Bleuse, Mathieu Puyade, Guillaume Moulis, A. Néel, Noémie Abisror, Antoine Baudet, Bernard Bonnotte, Jérémie Dion, Antoine Doss…
ABSTRACT Background Hypereosinophilic syndromes (HES) are a heterogenous group of eosinophilic disorders. To date, only retrospective studies of limited sample‐size and/or follow‐up duration are available. Methods The COHESion study is a national prospective multicenter multidisciplinary cohort recruiting both adults or children with the spectrum of eosinophilic disorders (including reactive HE/HES [HE/HES‐R], idiopathic HES [HES‐I], lymphocytic HES [HES‐L], neoplastic HE/HES [HE/HES‐N], HE of unknown significance…