Hyperglycemia Interacts with Ischemia in a Synergistic Way on Wound Repair and Myofibroblast Differentiation Article Swipe
Mickaël Tobalem
,
Dominik André‐Lévigne
,
Ali Modarressi
,
Fatemeh Atashi
,
Frédéric Villard
,
Boris Hinz
,
Brigitte Pittet‐Cuénod
·
YOU?
·
· 2015
· Open Access
·
· DOI: https://doi.org/10.1097/gox.0000000000000443
YOU?
·
· 2015
· Open Access
·
· DOI: https://doi.org/10.1097/gox.0000000000000443
Our model allows to specifically quantify the effect of hyperglycemia and ischemia alone or in combination on wound repair. We show that hyperglycemia amplifies the inhibitory effect of ischemia on wound repair and myofibroblast expression. Our data reveal for the first time the synergic aspect of this interaction and therefore stress the importance of a strict glycemic control in the management of ischemic wounds.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1097/gox.0000000000000443
- OA Status
- gold
- Cited By
- 18
- References
- 33
- Related Works
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- OpenAlex ID
- https://openalex.org/W2461102356
All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W2461102356Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1097/gox.0000000000000443Digital Object Identifier
- Title
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Hyperglycemia Interacts with Ischemia in a Synergistic Way on Wound Repair and Myofibroblast DifferentiationWork title
- Type
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articleOpenAlex work type
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enPrimary language
- Publication year
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2015Year of publication
- Publication date
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2015-07-01Full publication date if available
- Authors
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Mickaël Tobalem, Dominik André‐Lévigne, Ali Modarressi, Fatemeh Atashi, Frédéric Villard, Boris Hinz, Brigitte Pittet‐CuénodList of authors in order
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https://doi.org/10.1097/gox.0000000000000443Publisher landing page
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goldOpen access status per OpenAlex
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https://doi.org/10.1097/gox.0000000000000443Direct OA link when available
- Concepts
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Myofibroblast, Medicine, Ischemia, Wound healing, Contraction (grammar), Surgery, Pathology, Internal medicine, FibrosisTop concepts (fields/topics) attached by OpenAlex
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18Total citation count in OpenAlex
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2024: 1, 2023: 3, 2022: 1, 2021: 5, 2020: 3Per-year citation counts (last 5 years)
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33Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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