Hypofraktionierte Strahlentherapie – ein modernisierter Klassiker Article Swipe

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Roland Merten , Hans Christiansen , P. Ivanyi , Marcel Lafos , Christoph A. J. von Klot , Anne Caroline Knöchelmann ·

YOU? · · 2022 · Open Access · · DOI: https://doi.org/10.1007/s00761-022-01196-7

Zusammenfassung Die Nutzung unterschiedlicher Fraktionierungskonzepte in der Strahlentherapie ist seit über 100 Jahren Gegenstand der präklinischen und klinischen Forschung. Als Hypofraktionierung bezeichnet man dabei die Nutzung höherer Einzeldosen als 2,0 Gy bei insgesamt niedrigerer Gesamtdosis, was bei gleicher biologischer Effektivität die Behandlungszeit verkürzt. Inzwischen sind insbesondere für die definitive Strahlentherapie des Prostatakarzinoms, für die adjuvante Strahlentherapie des Mammakarzinoms und Glioblastoms und für die palliative Bestrahlung von Metastasen multimodale Konzepte unter Einbeziehung hypofraktionierter Bestrahlungskonzepte fest etabliert und deren Langzeitverträglichkeit in der Literatur gut dokumentiert. Einige Therapiekonzepte sind bereits in der klinischen Routine angekommen. Der Beitrag gibt einen Überblick über die häufigsten und neueren Indikationen der zumeist moderat (in der Regel bis 3,0 Gy Einzeldosis) hypofraktionierten Strahlentherapie und Radiochemotherapie.

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Medicine

Gynaecology

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Medicine Gynecology

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Type: article
Language: de
Landing Page: https://doi.org/10.1007/s00761-022-01196-7
PDF: https://link.springer.com/content/pdf/10.1007/s00761-022-01196-7.pdf
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Cited By: 1
References: 32
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OpenAlex ID: https://openalex.org/W4282935962

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DOI: https://doi.org/10.1007/s00761-022-01196-7

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Title: Hypofraktionierte Strahlentherapie – ein modernisierter Klassiker

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Type: article

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Language: de

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Publication year: 2022

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Publication date: 2022-06-15

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Authors: Roland Merten, Hans Christiansen, P. Ivanyi, Marcel Lafos, Christoph A. J. von Klot, Anne Caroline Knöchelmann

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Landing page: https://doi.org/10.1007/s00761-022-01196-7

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Concepts: Medicine, Gynecology

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Cited by: 1

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sustainable_development_goals[0].id	https://metadata.un.org/sdg/3
sustainable_development_goals[0].score	0.5299999713897705
sustainable_development_goals[0].display_name	Good health and well-being
citation_normalized_percentile.value	0.56422139
citation_normalized_percentile.is_in_top_1_percent	False
citation_normalized_percentile.is_in_top_10_percent	False