Disruption of hierarchical predictive coding during sleep Article Swipe
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· 2015
· Open Access
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· DOI: https://doi.org/10.1073/pnas.1501026112
· OA: W2016127971
Significance Sleeping disrupts the conscious awareness of external sounds. We investigated the stage of processing at which this disruption occurs. In the awake brain, when a regular sequence of sounds is presented, a hierarchy of brain areas uses the available regularities to predict forthcoming sounds and to respond with a series of “prediction error” signals when these predictions are violated. Using simultaneous recordings of electroencephalography and magnetoencephalography signals, we discovered that both short-term and long-term brain responses to auditory prediction errors are disrupted during non-rapid eye movement and rapid eye movement sleep; however, the brain still exhibits detectable auditory responses and a capacity to habituate to frequently repeated sounds. Thus, sleep appears to selectively affect the brain’s prediction and error detection systems.
