Developing a New Definition and Assessing New Clinical Criteria for Septic Shock Article Swipe

PDF

Related Concepts

septic shock medicine intensive care medicine epidemiology sepsis delphi method cohort cohort study emergency medicine internal medicine mathematics statistics

Manu Shankar‐Hari , Gary Phillips , Mitchell L. Levy , Christopher W. Seymour , Jean‐Louis Vincent , Clifford S. Deutschman , Derek C. Angus , Gordon D. Rubenfeld , Mervyn Singer ·

YOU? · · 2016 · Open Access · · DOI: https://doi.org/10.1001/jama.2016.0289 · OA: W2278600110

Based on a consensus process using results from a systematic review, surveys, and cohort studies, septic shock is defined as a subset of sepsis in which underlying circulatory, cellular, and metabolic abnormalities are associated with a greater risk of mortality than sepsis alone. Adult patients with septic shock can be identified using the clinical criteria of hypotension requiring vasopressor therapy to maintain mean BP 65 mm Hg or greater and having a serum lactate level greater than 2 mmol/L after adequate fluid resuscitation.