Randomized Trial of Longer-Term Therapy for Symptoms Attributed to Lyme Disease Article Swipe

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Medicine Lyme disease Doxycycline Randomized controlled trial Internal medicine Placebo Borrelia burgdorferi Randomization Ceftriaxone Clarithromycin Surgery Antibiotics Immunology Pathology Alternative medicine Biology Helicobacter pylori Microbiology Antibody

Anneleen Berende , Hadewych J. M. ter Hofstede , Fidel J. Vos , Henriët van Middendorp , Michiel L. Vogelaar , Mirjam Tromp , F.H.J. van den Hoogen , A. Rogier T. Donders , Andrea W.M. Evers , Bart Jan Kullberg ·

YOU? · · 2016 · Open Access · · DOI: https://doi.org/10.1056/nejmoa1505425 · OA: W2318919763

In patients with persistent symptoms attributed to Lyme disease, longer-term antibiotic treatment did not have additional beneficial effects on health-related quality of life beyond those with shorter-term treatment. (Funded by the Netherlands Organization for Health Research and Development ZonMw; PLEASE ClinicalTrials.gov number, NCT01207739.).