Intrapericardial Left Ventricular Assist Device for Advanced Heart Failure Article Swipe

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medicine ventricular assist device destination therapy heart failure clinical endpoint randomized controlled trial heart transplantation investigational device exemption confidence interval population ejection fraction stroke (engine) surgery cardiology relative risk internal medicine clinical trial mechanical engineering environmental health engineering

Joseph G. Rogers , Francis D. Pagani , Antone Tatooles , Geetha Bhat , Mark S. Slaughter , Emma J. Birks , Steven W. Boyce , Samer S. Najjar , Valluvan Jeevanandam , Allen S. Anderson , Igor D. Gregorič , Hari R. Mallidi , Katrin Leadley , Keith D. Aaronson , O.H. Frazier , Carmelo A. Milano ·

YOU? · · 2017 · Open Access · · DOI: https://doi.org/10.1056/nejmoa1602954 · OA: W2585810302

In this trial involving patients with advanced heart failure who were ineligible for heart transplantation, a small, intrapericardial, centrifugal-flow LVAD was found to be noninferior to an axial-flow LVAD with respect to survival free from disabling stroke or device removal for malfunction or failure. (Funded by HeartWare; ENDURANCE ClinicalTrials.gov number, NCT01166347 .).