T regulatory cells and dendritic cells protect against transfusion-related acute lung injury via IL-10 Article Swipe
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Rick Kapur
,
Michael D. Kim
,
Rukhsana Aslam
,
Mark J. McVey
,
Arata Tabuchi
,
Alice Luo
,
Jonathan Liu
,
Yuan Li
,
Shanjeevan Shanmugabhavananthan
,
Edwin R. Speck
,
Anne Zufferey
,
George M. Yousef
,
Haibo Zhang
,
Matthew T. Rondina
,
Andrew S. Weyrich
,
Leendert Porcelijn
,
Wolfgang M. Kuebler
,
Arthur S. Slutsky
,
John W. Semple
·
YOU?
·
· 2017
· Open Access
·
· DOI: https://doi.org/10.1182/blood-2016-12-758185
· OA: W2588946552
YOU?
·
· 2017
· Open Access
·
· DOI: https://doi.org/10.1182/blood-2016-12-758185
· OA: W2588946552
Key Points CD4+CD25+FoxP3+ T regulatory cells and CD11c+ dendritic cells protect against antibody-mediated murine TRALI. Murine TRALI is associated with reduced IL-10 levels, and IL-10 administration prevents and rescues TRALI development.
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