Laser‐Induced Focused Ultrasound for Cavitation Treatment: Toward High‐Precision Invisible Sonic Scalpel Article Swipe

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Materials science Photoacoustic imaging in biomedicine Cavitation Laser Ultrasound Ablation Photoacoustic Doppler effect Photoacoustic effect Optics Biomedical engineering Laser ablation Focused ultrasound High-intensity focused ultrasound Optoelectronics Acoustics Aerospace engineering Engineering Medicine Physics

Taehwa Lee , Wei Luo , Qiaochu Li , Hakan Demirci , L. Jay Guo ·

YOU? · · 2017 · Open Access · · DOI: https://doi.org/10.1002/smll.201701555 · OA: W2748846014

Beyond the implementation of the photoacoustic effect to photoacoustic imaging and laser ultrasonics, this study demonstrates a novel application of the photoacoustic effect for high‐precision cavitation treatment of tissue using laser‐induced focused ultrasound. The focused ultrasound is generated by pulsed optical excitation of an efficient photoacoustic film coated on a concave surface, and its amplitude is high enough to produce controllable microcavitation within the focal region (lateral focus <100 µm). Such microcavitation is used to cut or ablate soft tissue in a highly precise manner. This work demonstrates precise cutting of tissue‐mimicking gels as well as accurate ablation of gels and animal eye tissues.