Genome-wide association and genomic prediction of resistance to viral nervous necrosis in European sea bass (Dicentrarchus labrax) using RAD sequencing Article Swipe

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Dicentrarchus Biology Sea bass Genome Genome-wide association study DNA sequencing Evolutionary biology Genomic selection Genetics Computational biology Fishery Single-nucleotide polymorphism Fish <Actinopterygii> Gene Genotype

Christos Palaiokostas , Sophie Cariou , Anastasia Bestin , Jean-Sébastien Bruant , Pierrick Haffray , Thierry Morin , Joëlle Cabon , François Allal , Marc Vandeputte , Ross D. Houston ·

YOU? · · 2018 · Open Access · · DOI: https://doi.org/10.1186/s12711-018-0401-2 · OA: W2805462056

Genome-wide significant QTL were identified but each with relatively small effects on the trait. Tests of genomic prediction suggested that incorporating genome-wide SNP data is likely to result in higher accuracy of estimated breeding values for resistance to VNN. RAD sequencing is an effective method for generating such genome-wide SNPs, and our findings highlight the potential of genomic selection to breed farmed European sea bass with improved resistance to VNN.