In Vitro and In Vivo Evaluation of APX001A/APX001 and Other Gwt1 Inhibitors against Cryptococcus Article Swipe
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Karen Joy Shaw
,
Wiley A. Schell
,
Jonathan A. Covel
,
Gisele Duboc
,
Charles Giamberardino
,
Mili Kapoor
,
Molly Moloney
,
Quinlyn A. Soltow
,
Jennifer L. Tenor
,
Dena L. Toffaletti
,
Michael Trzoss
,
Peter J. Webb
,
John R. Perfect
·
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.1128/aac.00523-18
· OA: W2805470919
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.1128/aac.00523-18
· OA: W2805470919
Cryptococcal meningitis (CM), caused primarily by Cryptococcus neoformans , is uniformly fatal if not treated. Treatment options are limited, especially in resource-poor geographical regions, and mortality rates remain high despite current therapies.
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