Initial Invasive or Conservative Strategy for Stable Coronary Disease Article Swipe

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Medicine Medical therapy Coronary disease Disease Cardiology Intensive care medicine Intervention (counseling) Internal medicine Coronary heart disease Psychiatry

David J. Maron , Judith S. Hochman , Harmony R. Reynolds , Sripal Bangalore , Sean M. O’Brien , William E. Boden , Bernard Chaitman , Roxy Senior , José López-Sendón , Karen P. Alexander , Renato D. Lópes , Leslee J. Shaw , Jeffrey S. Berger , Jonathan Newman , Mandeep S. Sidhu , Shaun G. Goodman , Witold Rużyłło , Gilbert Gosselin , Aldo P. Maggioni , Harvey D. White , Balram Bhargava , James K. Min , G.B. John Mancini , Daniel S. Berman , Michael H. Picard , Raymond Y. Kwong , Ziad A. Ali , Daniel B. Mark , John A. Spertus , M.N. Krishnan , Ahmed Elghamaz , Nagaraja Moorthy , Whady Hueb , Marcin Demkow , Kreton Mavromatis , O.L. Bockeria , Jesús Peteiro , Todd D. Miller , Hanna Szwed , Rolf Doerr , Mátyás Keltai , Joseph B. Selvanayagam , Philippe Gabríel Steg , Claes Held , Shun Kohsaka , Stavroula Mavromichalis , Ruth Kirby , Neal Jeffries , Frank E. Harrell , Frank W. Rockhold , Samuel Broderick , T. Bruce Ferguson , David O. Williams , Robert A. Harrington , Gregg W. Stone , Yves Rosenberg ·

YOU? · · 2020 · Open Access · · DOI: https://doi.org/10.1056/nejmoa1915922 · OA: W3014025744

Among patients with stable coronary disease and moderate or severe ischemia, we did not find evidence that an initial invasive strategy, as compared with an initial conservative strategy, reduced the risk of ischemic cardiovascular events or death from any cause over a median of 3.2 years. The trial findings were sensitive to the definition of myocardial infarction that was used. (Funded by the National Heart, Lung, and Blood Institute and others; ISCHEMIA ClinicalTrials.gov number, NCT01471522.).