IgG4-Related Sclerosing Cholangitis Mimicking Cholangiocarcinoma Article Swipe
Phạm Minh Thông
,
Vu Dang Luu
,
Thieu‐Thi Tra My
,
Nguyễn Xuân Hiền
,
Trần Anh Tuấn
,
Nguyễn Minh Đức
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1159/000513029
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1159/000513029
IgG4-related sclerosing cholangitis (IgG4-SC) is a relatively newly identified disease that is frequently associated with autoimmune pancreatitis. The differential diagnosis between cholangiocarcinoma, primary sclerosing cholangitis, and IgG4-SC can be challenging due to significant overlap among the clinical and imaging characteristics. We report the case of a 71-year-old woman who was diagnosed with IgG4-related disease based on increased serum IgG4 levels, imaging, and clinical presentation, which showed systemic involvement, including sclerosing cholangitis and kidneys. The patient presented with chronic jaundice. Magnetic resonance imaging revealed bile duct strictures and the dilatation of upstream bile ducts, smooth wall thickening with uniform enhancement in the delayed phase, and no vascular infiltration. Multiple low-density, wedge-shaped areas were identified in both kidneys, which were hypointense on T2-weighted images and hyperintense on diffusion-weighted images. The serum IgG4 levels of this patient were elevated to nearly 10-fold the normal upper limit. A diagnosis of IgG4-SC associated with IgG4-related kidney was made. Based on this case, pre-surgery IgG4 serum treatment in patients with non-malignant bile duct stenosis was recommended to exclude IgG4-SC.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1159/000513029
- https://www.karger.com/Article/Pdf/513029
- OA Status
- gold
- Cited By
- 2
- References
- 15
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3130932833
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3130932833Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1159/000513029Digital Object Identifier
- Title
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IgG4-Related Sclerosing Cholangitis Mimicking CholangiocarcinomaWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2021Year of publication
- Publication date
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2021-02-18Full publication date if available
- Authors
-
Phạm Minh Thông, Vu Dang Luu, Thieu‐Thi Tra My, Nguyễn Xuân Hiền, Trần Anh Tuấn, Nguyễn Minh ĐứcList of authors in order
- Landing page
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https://doi.org/10.1159/000513029Publisher landing page
- PDF URL
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https://www.karger.com/Article/Pdf/513029Direct link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
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https://www.karger.com/Article/Pdf/513029Direct OA link when available
- Concepts
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Medicine, Autoimmune pancreatitis, Primary sclerosing cholangitis, Bile duct, Differential diagnosis, Magnetic resonance imaging, Porta hepatis, Gastroenterology, Stenosis, Radiology, Pathology, Jaundice, Internal medicine, Pancreatitis, DiseaseTop concepts (fields/topics) attached by OpenAlex
- Cited by
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2Total citation count in OpenAlex
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2025: 1, 2023: 1Per-year citation counts (last 5 years)
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15Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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