Illuminating the Live-Cell Dynamics of Hepatitis B Virus Covalently Closed Circular DNA Using the CRISPR-Tag System Article Swipe
Related Concepts
cccDNA
HBx
Biology
Virology
Circular DNA
Hepatitis B virus
Virus
Cell biology
Genetics
Gene
Genome
HBsAg
Jiahui Ding
,
Zhigang Yi
,
Wenjing Zai
,
Min Wu
,
Baohui Chen
,
Qiliang Cai
,
Xiaonan Zhang
,
Zhenghong Yuan
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1128/mbio.03550-22
· OA: W4321493134
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1128/mbio.03550-22
· OA: W4321493134
Understanding the formation and maintenance of HBV cccDNA has always been a central issue in the study of HBV pathobiology. However, little progress has been made due to the lack of robust assay systems and its resistance to genetic modification.
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