Impact of donor cardiopulmonary resuscitation on the outcome of simultaneous pancreas–kidney transplantation—a retrospective study Article Swipe
Jannik Hinzmann
,
Sascha Grzella
,
Thorsten Lengenfeld
,
Nina Pillokeit
,
Marielle Hummels
,
Hans‐Martin Vaihinger
,
Timm H. Westhoff
,
Richard Viebahn
,
Peter Schenker
·
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1111/tri.13588
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1111/tri.13588
Previous cardiac arrest in brain-dead donors has been discussed as a potential risk factor in pancreas transplantation (PT), leading to a higher rate of organ refusal. This study aimed to assess the impact of cardiopulmonary resuscitation (CPR) in brain-dead donors on pancreas transplant outcome. A total of 518 type 1 diabetics underwent primary simultaneous pancreas-kidney (SPK) transplantation at our center between 1994 and 2018. Patients were divided into groups, depending on whether their donor had been resuscitated or not. A total of 91 (17.6%) post-CPR donors had been accepted for transplantation (mean duration of cardiac arrest, 19.4 ± 15.6 min). Those donors were younger (P < 0.001), had lower pancreas donor risk index (PDRI, P = 0.003), and had higher serum creatinine levels (P = 0.021). With a median follow-up of 167 months (IQR 82-229), both groups demonstrated comparable short- and long-term patient and graft survival. The resuscitation time (<20 min vs. ≥20 min) also showed no impact, with similar survival rates for both groups. A multivariable Cox regression analysis suggested no statistically significant association between donor CPR and patient or graft survival. Our results indicate that post-CPR brain-dead donors are suitable for PT without increasing the risk of complications.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1111/tri.13588
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/tri.13588
- OA Status
- hybrid
- Cited By
- 6
- References
- 38
- Related Works
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- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3003535026Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1111/tri.13588Digital Object Identifier
- Title
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Impact of donor cardiopulmonary resuscitation on the outcome of simultaneous pancreas–kidney transplantation—a retrospective studyWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2020Year of publication
- Publication date
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2020-02-03Full publication date if available
- Authors
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Jannik Hinzmann, Sascha Grzella, Thorsten Lengenfeld, Nina Pillokeit, Marielle Hummels, Hans‐Martin Vaihinger, Timm H. Westhoff, Richard Viebahn, Peter SchenkerList of authors in order
- Landing page
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https://doi.org/10.1111/tri.13588Publisher landing page
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/tri.13588Direct link to full text PDF
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YesWhether a free full text is available
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hybridOpen access status per OpenAlex
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/tri.13588Direct OA link when available
- Concepts
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Medicine, Cardiopulmonary resuscitation, Resuscitation, Transplantation, Pancreas transplantation, Creatinine, Nephrology, Kidney transplantation, Retrospective cohort study, Pancreas, Surgery, Brain dead, Risk factor, Internal medicineTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
6Total citation count in OpenAlex
- Citations by year (recent)
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2025: 3, 2023: 2, 2022: 1Per-year citation counts (last 5 years)
- References (count)
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38Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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