Impact of US Public Health Service increased risk deceased donor designation on organ utilization Article Swipe
Mathew R. P. Sapiano
,
Jefferson M. Jones
,
James Bowman
,
Marilyn E. Levi
,
Sridhar V. Basavaraju
·
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1111/ajt.15388
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1111/ajt.15388
Under US Public Health Service guidelines, organ donors with risk factors for human immunodeficiency virus (HIV), hepatitis B virus (HBV), or hepatitis C virus (HCV) are categorized as increased risk donors (IRD). Previous studies have suggested that IRD organs are utilized at lower rates than organs from standard risk donors (SRD), but these studies were conducted prior to universal donor nucleic acid test screening. We conducted risk-adjusted analyses to determine the effect of IRD designation on organ utilization using 2010-2017 data (21 626 heart, 101 160 kidney, 52 714 liver, and 16 219 lung recipients in the United States) from the Organ Procurement and Transplantation Network. There was no significant difference (P < .05) between risk-adjusted utilization rates for IRD vs SRD organs for adult hearts and livers and pediatric kidneys, livers, and lungs. Significantly lower utilization was found among IRD adult kidneys, lungs, and pediatric hearts. Analysis of the proportion of transplanted organs recovered from IRD by facility suggests that a subset of facilities contribute to the underutilization of adult IRD kidneys. Along with revised criteria and nomenclature to identify donors with HIV, HBV, or HCV risk factors, educational efforts to standardize informed consent discussions might improve organ utilization.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1111/ajt.15388
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ajt.15388
- OA Status
- hybrid
- Cited By
- 34
- References
- 17
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2937296274
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2937296274Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1111/ajt.15388Digital Object Identifier
- Title
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Impact of US Public Health Service increased risk deceased donor designation on organ utilizationWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2019Year of publication
- Publication date
-
2019-04-08Full publication date if available
- Authors
-
Mathew R. P. Sapiano, Jefferson M. Jones, James Bowman, Marilyn E. Levi, Sridhar V. BasavarajuList of authors in order
- Landing page
-
https://doi.org/10.1111/ajt.15388Publisher landing page
- PDF URL
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ajt.15388Direct link to full text PDF
- Open access
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YesWhether a free full text is available
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hybridOpen access status per OpenAlex
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ajt.15388Direct OA link when available
- Concepts
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Medicine, Organ procurement, Organ donation, Hepatitis B virus, Transplantation, Public health, Organ transplantation, Hepatitis B, Internal medicine, Intensive care medicine, Immunology, Virus, PathologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
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34Total citation count in OpenAlex
- Citations by year (recent)
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2025: 4, 2024: 6, 2023: 4, 2022: 6, 2021: 6Per-year citation counts (last 5 years)
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17Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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