Implementation of Multigene Germline and Parallel Somatic Genetic Testing in Epithelial Ovarian Cancer: SIGNPOST Study Article Swipe
Dhivya Chandrasekaran
,
Monika Sobočan
,
Oleg Blyuss
,
Rowan Miller
,
Olivia Evans
,
Shanthini Mary Crusz
,
Tina Mills‐Baldock
,
Li Sun
,
Rory F.L. Hammond
,
Faiza Gaba
,
Lucy Jenkins
,
Munaza Ahmed
,
Ajith Kumar
,
Arjun Jeyarajah
,
Alexandra Lawrence
,
Elly Brockbank
,
Saurabh Phadnis
,
Mary Quigley
,
Fatima El Khouly
,
Rekha Wuntakal
,
Asma Faruqi
,
Giorgia Trevisan
,
Laura Casey
,
George J. Burghel
,
Hélene Schlecht
,
Michael Bulman
,
Philip Smith
,
Naomi L. Bowers
,
Rosa Legood
,
Michelle Lockley
,
Andrew J. Wallace
,
Naveena Singh
,
D. Gareth Evans
,
Ranjit Manchanda
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.3390/cancers13174344
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.3390/cancers13174344
We present findings of a cancer multidisciplinary-team (MDT) coordinated mainstreaming pathway of unselected 5-panel germline BRCA1/BRCA2/RAD51C/RAD51D/BRIP1 and parallel somatic BRCA1/BRCA2 testing in all women with epithelial-OC and highlight the discordance between germline and somatic testing strategies across two cancer centres. Patients were counselled and consented by a cancer MDT member. The uptake of parallel multi-gene germline and somatic testing was 97.7%. Counselling by clinical-nurse-specialist more frequently needed >1 consultation (53.6% (30/56)) compared to a medical (15.0% (21/137)) or surgical oncologist (15.3% (17/110)) (p < 0.001). The median age was 54 (IQR = 51–62) years in germline pathogenic-variant (PV) versus 61 (IQR = 51–71) in BRCA wild-type (p = 0.001). There was no significant difference in distribution of PVs by ethnicity, stage, surgery timing or resection status. A total of 15.5% germline and 7.8% somatic BRCA1/BRCA2 PVs were identified. A total of 2.3% patients had RAD51C/RAD51D/BRIP1 PVs. A total of 11% germline PVs were large-genomic-rearrangements and missed by somatic testing. A total of 20% germline PVs are missed by somatic first BRCA-testing approach and 55.6% germline PVs missed by family history ascertainment. The somatic testing failure rate is higher (23%) for patients undergoing diagnostic biopsies. Our findings favour a prospective parallel somatic and germline panel testing approach as a clinically efficient strategy to maximise variant identification. UK Genomics test-directory criteria should be expanded to include a panel of OC genes.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/cancers13174344
- https://www.mdpi.com/2072-6694/13/17/4344/pdf?version=1630291414
- OA Status
- gold
- Cited By
- 49
- References
- 55
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3198033444
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W3198033444Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.3390/cancers13174344Digital Object Identifier
- Title
-
Implementation of Multigene Germline and Parallel Somatic Genetic Testing in Epithelial Ovarian Cancer: SIGNPOST StudyWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2021Year of publication
- Publication date
-
2021-08-27Full publication date if available
- Authors
-
Dhivya Chandrasekaran, Monika Sobočan, Oleg Blyuss, Rowan Miller, Olivia Evans, Shanthini Mary Crusz, Tina Mills‐Baldock, Li Sun, Rory F.L. Hammond, Faiza Gaba, Lucy Jenkins, Munaza Ahmed, Ajith Kumar, Arjun Jeyarajah, Alexandra Lawrence, Elly Brockbank, Saurabh Phadnis, Mary Quigley, Fatima El Khouly, Rekha Wuntakal, Asma Faruqi, Giorgia Trevisan, Laura Casey, George J. Burghel, Hélene Schlecht, Michael Bulman, Philip Smith, Naomi L. Bowers, Rosa Legood, Michelle Lockley, Andrew J. Wallace, Naveena Singh, D. Gareth Evans, Ranjit ManchandaList of authors in order
- Landing page
-
https://doi.org/10.3390/cancers13174344Publisher landing page
- PDF URL
-
https://www.mdpi.com/2072-6694/13/17/4344/pdf?version=1630291414Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://www.mdpi.com/2072-6694/13/17/4344/pdf?version=1630291414Direct OA link when available
- Concepts
-
Germline, Germline mutation, Somatic cell, Medicine, Genetic testing, Oncology, Internal medicine, Cancer, Ovarian cancer, Genetics, Gynecology, Biology, Mutation, GeneTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
49Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 9, 2024: 15, 2023: 10, 2022: 15Per-year citation counts (last 5 years)
- References (count)
-
55Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W3198033444 |
|---|---|
| doi | https://doi.org/10.3390/cancers13174344 |
| ids.doi | https://doi.org/10.3390/cancers13174344 |
| ids.mag | 3198033444 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/34503154 |
| ids.openalex | https://openalex.org/W3198033444 |
| fwci | 7.4889427 |
| type | article |
| title | Implementation of Multigene Germline and Parallel Somatic Genetic Testing in Epithelial Ovarian Cancer: SIGNPOST Study |
| awards[0].id | https://openalex.org/G277970949 |
| awards[0].funder_id | https://openalex.org/F4320315977 |
| awards[0].display_name | |
| awards[0].funder_award_id | ECMG1B6R |
| awards[0].funder_display_name | Barts Charity |
| biblio.issue | 17 |
| biblio.volume | 13 |
| biblio.last_page | 4344 |
| biblio.first_page | 4344 |
| topics[0].id | https://openalex.org/T10769 |
| topics[0].field.id | https://openalex.org/fields/13 |
| topics[0].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[0].score | 0.9998999834060669 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/1311 |
| topics[0].subfield.display_name | Genetics |
| topics[0].display_name | BRCA gene mutations in cancer |
| topics[1].id | https://openalex.org/T10550 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9991000294685364 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2743 |
| topics[1].subfield.display_name | Reproductive Medicine |
| topics[1].display_name | Ovarian cancer diagnosis and treatment |
| topics[2].id | https://openalex.org/T11287 |
| topics[2].field.id | https://openalex.org/fields/13 |
| topics[2].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[2].score | 0.9972000122070312 |
| topics[2].domain.id | https://openalex.org/domains/1 |
| topics[2].domain.display_name | Life Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/1306 |
| topics[2].subfield.display_name | Cancer Research |
| topics[2].display_name | Cancer Genomics and Diagnostics |
| funders[0].id | https://openalex.org/F4320315977 |
| funders[0].ror | https://ror.org/0513pp416 |
| funders[0].display_name | Barts Charity |
| is_xpac | False |
| apc_list.value | 2400 |
| apc_list.currency | CHF |
| apc_list.value_usd | 2598 |
| apc_paid.value | 2400 |
| apc_paid.currency | CHF |
| apc_paid.value_usd | 2598 |
| concepts[0].id | https://openalex.org/C109825262 |
| concepts[0].level | 3 |
| concepts[0].score | 0.863813042640686 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q1139164 |
| concepts[0].display_name | Germline |
| concepts[1].id | https://openalex.org/C13514818 |
| concepts[1].level | 4 |
| concepts[1].score | 0.7135193347930908 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q5552256 |
| concepts[1].display_name | Germline mutation |
| concepts[2].id | https://openalex.org/C134305767 |
| concepts[2].level | 3 |
| concepts[2].score | 0.6307539939880371 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q725508 |
| concepts[2].display_name | Somatic cell |
| concepts[3].id | https://openalex.org/C71924100 |
| concepts[3].level | 0 |
| concepts[3].score | 0.6069878935813904 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[3].display_name | Medicine |
| concepts[4].id | https://openalex.org/C2780673598 |
| concepts[4].level | 2 |
| concepts[4].score | 0.5798054337501526 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q285223 |
| concepts[4].display_name | Genetic testing |
| concepts[5].id | https://openalex.org/C143998085 |
| concepts[5].level | 1 |
| concepts[5].score | 0.4972279369831085 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q162555 |
| concepts[5].display_name | Oncology |
| concepts[6].id | https://openalex.org/C126322002 |
| concepts[6].level | 1 |
| concepts[6].score | 0.4702005982398987 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[6].display_name | Internal medicine |
| concepts[7].id | https://openalex.org/C121608353 |
| concepts[7].level | 2 |
| concepts[7].score | 0.45111703872680664 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q12078 |
| concepts[7].display_name | Cancer |
| concepts[8].id | https://openalex.org/C2780427987 |
| concepts[8].level | 3 |
| concepts[8].score | 0.43329566717147827 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q172341 |
| concepts[8].display_name | Ovarian cancer |
| concepts[9].id | https://openalex.org/C54355233 |
| concepts[9].level | 1 |
| concepts[9].score | 0.34277260303497314 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q7162 |
| concepts[9].display_name | Genetics |
| concepts[10].id | https://openalex.org/C29456083 |
| concepts[10].level | 1 |
| concepts[10].score | 0.33925509452819824 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q1221899 |
| concepts[10].display_name | Gynecology |
| concepts[11].id | https://openalex.org/C86803240 |
| concepts[11].level | 0 |
| concepts[11].score | 0.2919001877307892 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[11].display_name | Biology |
| concepts[12].id | https://openalex.org/C501734568 |
| concepts[12].level | 3 |
| concepts[12].score | 0.18199065327644348 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q42918 |
| concepts[12].display_name | Mutation |
| concepts[13].id | https://openalex.org/C104317684 |
| concepts[13].level | 2 |
| concepts[13].score | 0.11400756239891052 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q7187 |
| concepts[13].display_name | Gene |
| keywords[0].id | https://openalex.org/keywords/germline |
| keywords[0].score | 0.863813042640686 |
| keywords[0].display_name | Germline |
| keywords[1].id | https://openalex.org/keywords/germline-mutation |
| keywords[1].score | 0.7135193347930908 |
| keywords[1].display_name | Germline mutation |
| keywords[2].id | https://openalex.org/keywords/somatic-cell |
| keywords[2].score | 0.6307539939880371 |
| keywords[2].display_name | Somatic cell |
| keywords[3].id | https://openalex.org/keywords/medicine |
| keywords[3].score | 0.6069878935813904 |
| keywords[3].display_name | Medicine |
| keywords[4].id | https://openalex.org/keywords/genetic-testing |
| keywords[4].score | 0.5798054337501526 |
| keywords[4].display_name | Genetic testing |
| keywords[5].id | https://openalex.org/keywords/oncology |
| keywords[5].score | 0.4972279369831085 |
| keywords[5].display_name | Oncology |
| keywords[6].id | https://openalex.org/keywords/internal-medicine |
| keywords[6].score | 0.4702005982398987 |
| keywords[6].display_name | Internal medicine |
| keywords[7].id | https://openalex.org/keywords/cancer |
| keywords[7].score | 0.45111703872680664 |
| keywords[7].display_name | Cancer |
| keywords[8].id | https://openalex.org/keywords/ovarian-cancer |
| keywords[8].score | 0.43329566717147827 |
| keywords[8].display_name | Ovarian cancer |
| keywords[9].id | https://openalex.org/keywords/genetics |
| keywords[9].score | 0.34277260303497314 |
| keywords[9].display_name | Genetics |
| keywords[10].id | https://openalex.org/keywords/gynecology |
| keywords[10].score | 0.33925509452819824 |
| keywords[10].display_name | Gynecology |
| keywords[11].id | https://openalex.org/keywords/biology |
| keywords[11].score | 0.2919001877307892 |
| keywords[11].display_name | Biology |
| keywords[12].id | https://openalex.org/keywords/mutation |
| keywords[12].score | 0.18199065327644348 |
| keywords[12].display_name | Mutation |
| keywords[13].id | https://openalex.org/keywords/gene |
| keywords[13].score | 0.11400756239891052 |
| keywords[13].display_name | Gene |
| language | en |
| locations[0].id | doi:10.3390/cancers13174344 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S168415115 |
| locations[0].source.issn | 2072-6694 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 2072-6694 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Cancers |
| locations[0].source.host_organization | https://openalex.org/P4310310987 |
| locations[0].source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310310987 |
| locations[0].source.host_organization_lineage_names | Multidisciplinary Digital Publishing Institute |
| locations[0].license | cc-by |
| locations[0].pdf_url | https://www.mdpi.com/2072-6694/13/17/4344/pdf?version=1630291414 |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Cancers |
| locations[0].landing_page_url | https://doi.org/10.3390/cancers13174344 |
| locations[1].id | pmid:34503154 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Cancers |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/34503154 |
| locations[2].id | pmh:oai:researchonline.lshtm.ac.uk:4662756 |
| locations[2].is_oa | False |
| locations[2].source.id | https://openalex.org/S4306402527 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | LSHTM Research Online (London School of Hygiene and Tropical Medicine) |
| locations[2].source.host_organization | https://openalex.org/I4210089966 |
| locations[2].source.host_organization_name | London School of Hygiene & Tropical Medicine |
| locations[2].source.host_organization_lineage | https://openalex.org/I4210089966 |
| locations[2].license | |
| locations[2].pdf_url | |
| locations[2].version | acceptedVersion |
| locations[2].raw_type | Article |
| locations[2].license_id | |
| locations[2].is_accepted | True |
| locations[2].is_published | False |
| locations[2].raw_source_name | |
| locations[2].landing_page_url | https://researchonline.lshtm.ac.uk/view/creators/lsh1511505.html>; |
| locations[3].id | pmh:oai:pure.atira.dk:publications/393c4fff-3040-43e7-9b38-7aeb6cdda10d |
| locations[3].is_oa | True |
| locations[3].source.id | https://openalex.org/S4306400216 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | Research Portal (King's College London) |
| locations[3].source.host_organization | https://openalex.org/I183935753 |
| locations[3].source.host_organization_name | King's College London |
| locations[3].source.host_organization_lineage | https://openalex.org/I183935753 |
| locations[3].license | |
| locations[3].pdf_url | https://www.research.manchester.ac.uk/portal/en/publications/implementation-of-multigene-germline-and-parallel-somatic-genetic-testing-in-epithelial-ovarian-cancer-signpost-study(393c4fff-3040-43e7-9b38-7aeb6cdda10d).html |
| locations[3].version | submittedVersion |
| locations[3].raw_type | |
| locations[3].license_id | |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | |
| locations[3].landing_page_url | |
| locations[4].id | pmh:oai:uhra.herts.ac.uk:2299/25026 |
| locations[4].is_oa | True |
| locations[4].source.id | https://openalex.org/S4306400241 |
| locations[4].source.issn | |
| locations[4].source.type | repository |
| locations[4].source.is_oa | False |
| locations[4].source.issn_l | |
| locations[4].source.is_core | False |
| locations[4].source.is_in_doaj | False |
| locations[4].source.display_name | University of Hertfordshire Research Archive (University of Hertfordshire) |
| locations[4].source.host_organization | https://openalex.org/I141584323 |
| locations[4].source.host_organization_name | University of Hertfordshire |
| locations[4].source.host_organization_lineage | https://openalex.org/I141584323 |
| locations[4].license | |
| locations[4].pdf_url | http://hdl.handle.net/2299/25026 |
| locations[4].version | submittedVersion |
| locations[4].raw_type | |
| locations[4].license_id | |
| locations[4].is_accepted | False |
| locations[4].is_published | False |
| locations[4].raw_source_name | |
| locations[4].landing_page_url | http://hdl.handle.net/2299/25026 |
| locations[5].id | pmh:oai:doaj.org/article:a118176a5e304ad38cd052d2442e48ce |
| locations[5].is_oa | True |
| locations[5].source.id | https://openalex.org/S4306401280 |
| locations[5].source.issn | |
| locations[5].source.type | repository |
| locations[5].source.is_oa | False |
| locations[5].source.issn_l | |
| locations[5].source.is_core | False |
| locations[5].source.is_in_doaj | False |
| locations[5].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[5].source.host_organization | |
| locations[5].source.host_organization_name | |
| locations[5].license | cc-by-sa |
| locations[5].pdf_url | |
| locations[5].version | submittedVersion |
| locations[5].raw_type | article |
| locations[5].license_id | https://openalex.org/licenses/cc-by-sa |
| locations[5].is_accepted | False |
| locations[5].is_published | False |
| locations[5].raw_source_name | Cancers, Vol 13, Iss 4344, p 4344 (2021) |
| locations[5].landing_page_url | https://doaj.org/article/a118176a5e304ad38cd052d2442e48ce |
| locations[6].id | pmh:oai:mdpi.com:/2072-6694/13/17/4344/ |
| locations[6].is_oa | True |
| locations[6].source.id | https://openalex.org/S4306400947 |
| locations[6].source.issn | |
| locations[6].source.type | repository |
| locations[6].source.is_oa | True |
| locations[6].source.issn_l | |
| locations[6].source.is_core | False |
| locations[6].source.is_in_doaj | False |
| locations[6].source.display_name | MDPI (MDPI AG) |
| locations[6].source.host_organization | https://openalex.org/I4210097602 |
| locations[6].source.host_organization_name | Multidisciplinary Digital Publishing Institute (Switzerland) |
| locations[6].source.host_organization_lineage | https://openalex.org/I4210097602 |
| locations[6].license | cc-by |
| locations[6].pdf_url | |
| locations[6].version | submittedVersion |
| locations[6].raw_type | Text |
| locations[6].license_id | https://openalex.org/licenses/cc-by |
| locations[6].is_accepted | False |
| locations[6].is_published | False |
| locations[6].raw_source_name | Cancers; Volume 13; Issue 17; Pages: 4344 |
| locations[6].landing_page_url | https://dx.doi.org/10.3390/cancers13174344 |
| locations[7].id | pmh:oai:pubmedcentral.nih.gov:8431198 |
| locations[7].is_oa | True |
| locations[7].source.id | https://openalex.org/S2764455111 |
| locations[7].source.issn | |
| locations[7].source.type | repository |
| locations[7].source.is_oa | False |
| locations[7].source.issn_l | |
| locations[7].source.is_core | False |
| locations[7].source.is_in_doaj | False |
| locations[7].source.display_name | PubMed Central |
| locations[7].source.host_organization | https://openalex.org/I1299303238 |
| locations[7].source.host_organization_name | National Institutes of Health |
| locations[7].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[7].license | other-oa |
| locations[7].pdf_url | |
| locations[7].version | submittedVersion |
| locations[7].raw_type | Text |
| locations[7].license_id | https://openalex.org/licenses/other-oa |
| locations[7].is_accepted | False |
| locations[7].is_published | False |
| locations[7].raw_source_name | Cancers (Basel) |
| locations[7].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/8431198 |
| locations[8].id | pmh:oai:pure.atira.dk:openaire_cris_publications/393c4fff-3040-43e7-9b38-7aeb6cdda10d |
| locations[8].is_oa | True |
| locations[8].source.id | https://openalex.org/S4306400216 |
| locations[8].source.issn | |
| locations[8].source.type | repository |
| locations[8].source.is_oa | False |
| locations[8].source.issn_l | |
| locations[8].source.is_core | False |
| locations[8].source.is_in_doaj | False |
| locations[8].source.display_name | Research Portal (King's College London) |
| locations[8].source.host_organization | https://openalex.org/I183935753 |
| locations[8].source.host_organization_name | King's College London |
| locations[8].source.host_organization_lineage | https://openalex.org/I183935753 |
| locations[8].license | other-oa |
| locations[8].pdf_url | |
| locations[8].version | submittedVersion |
| locations[8].raw_type | article |
| locations[8].license_id | https://openalex.org/licenses/other-oa |
| locations[8].is_accepted | False |
| locations[8].is_published | False |
| locations[8].raw_source_name | Chandrasekaran, D, Sobocan, M, Blyuss, O, Miller, R E, Evans, O, Crusz, S M, Mills-baldock, T, Sun, L, Hammond, R F L, Gaba, F, Jenkins, L A, Ahmed, M, Kumar, A, Jeyarajah, A, Lawrence, A C, Brockbank, E, Phadnis, S, Quigley, M, El Khouly, F, Wuntakal, R, Faruqi, A, Trevisan, G, Casey, L, Burghel, G J, Schlecht, H, Bulman, M, Smith, P, Bowers, N L, Legood, R, Lockley, M, Wallace, A, Singh, N, Evans, D G & Manchanda, R 2021, 'Implementation of Multigene Germline and Parallel Somatic Genetic Testing in Epithelial Ovarian Cancer: SIGNPOST Study', Cancers, vol. 13, no. 17, 4344. https://doi.org/10.3390/cancers13174344 |
| locations[8].landing_page_url | https://research.manchester.ac.uk/en/publications/393c4fff-3040-43e7-9b38-7aeb6cdda10d |
| locations[9].id | pmh:oai:qmro.qmul.ac.uk:123456789/74102 |
| locations[9].is_oa | True |
| locations[9].source.id | https://openalex.org/S4306400530 |
| locations[9].source.issn | |
| locations[9].source.type | repository |
| locations[9].source.is_oa | False |
| locations[9].source.issn_l | |
| locations[9].source.is_core | False |
| locations[9].source.is_in_doaj | False |
| locations[9].source.display_name | Queen Mary Research Online (Queen Mary University of London) |
| locations[9].source.host_organization | https://openalex.org/I166337079 |
| locations[9].source.host_organization_name | Queen Mary University of London |
| locations[9].source.host_organization_lineage | https://openalex.org/I166337079 |
| locations[9].license | cc-by |
| locations[9].pdf_url | |
| locations[9].version | submittedVersion |
| locations[9].raw_type | Article |
| locations[9].license_id | https://openalex.org/licenses/cc-by |
| locations[9].is_accepted | False |
| locations[9].is_published | False |
| locations[9].raw_source_name | |
| locations[9].landing_page_url | https://qmro.qmul.ac.uk/xmlui/handle/123456789/74102 |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5103020322 |
| authorships[0].author.orcid | https://orcid.org/0009-0004-0917-3263 |
| authorships[0].author.display_name | Dhivya Chandrasekaran |
| authorships[0].countries | GB |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I166337079 |
| authorships[0].affiliations[0].raw_affiliation_string | Wolfson Institute of Population Health, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK |
| authorships[0].affiliations[1].institution_ids | https://openalex.org/I225661044 |
| authorships[0].affiliations[1].raw_affiliation_string | Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK |
| authorships[0].institutions[0].id | https://openalex.org/I225661044 |
| authorships[0].institutions[0].ror | https://ror.org/00b31g692 |
| authorships[0].institutions[0].type | healthcare |
| authorships[0].institutions[0].lineage | https://openalex.org/I225661044 |
| authorships[0].institutions[0].country_code | GB |
| authorships[0].institutions[0].display_name | Barts Health NHS Trust |
| authorships[0].institutions[1].id | https://openalex.org/I166337079 |
| authorships[0].institutions[1].ror | https://ror.org/026zzn846 |
| authorships[0].institutions[1].type | education |
| authorships[0].institutions[1].lineage | https://openalex.org/I124357947, https://openalex.org/I166337079 |
| authorships[0].institutions[1].country_code | GB |
| authorships[0].institutions[1].display_name | Queen Mary University of London |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Dhivya Chandrasekaran |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK, Wolfson Institute of Population Health, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK |
| authorships[1].author.id | https://openalex.org/A5024489382 |
| authorships[1].author.orcid | https://orcid.org/0000-0003-1384-9487 |
| authorships[1].author.display_name | Monika Sobočan |
| authorships[1].countries | GB, SI |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I166337079 |
| authorships[1].affiliations[0].raw_affiliation_string | Wolfson Institute of Population Health, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK |
| authorships[1].affiliations[1].institution_ids | https://openalex.org/I4210130844 |
| authorships[1].affiliations[1].raw_affiliation_string | Divison for Gynaecology and Perinatology, University Medical Centre Maribor, 2000 Maribor, Slovenia |
| authorships[1].affiliations[2].institution_ids | https://openalex.org/I225661044 |
| authorships[1].affiliations[2].raw_affiliation_string | Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK |
| authorships[1].institutions[0].id | https://openalex.org/I225661044 |
| authorships[1].institutions[0].ror | https://ror.org/00b31g692 |
| authorships[1].institutions[0].type | healthcare |
| authorships[1].institutions[0].lineage | https://openalex.org/I225661044 |
| authorships[1].institutions[0].country_code | GB |
| authorships[1].institutions[0].display_name | Barts Health NHS Trust |
| authorships[1].institutions[1].id | https://openalex.org/I166337079 |
| authorships[1].institutions[1].ror | https://ror.org/026zzn846 |
| authorships[1].institutions[1].type | education |
| authorships[1].institutions[1].lineage | https://openalex.org/I124357947, https://openalex.org/I166337079 |
| authorships[1].institutions[1].country_code | GB |
| authorships[1].institutions[1].display_name | Queen Mary University of London |
| authorships[1].institutions[2].id | https://openalex.org/I4210130844 |
| authorships[1].institutions[2].ror | https://ror.org/02rjj7s91 |
| authorships[1].institutions[2].type | healthcare |
| authorships[1].institutions[2].lineage | https://openalex.org/I4210130844 |
| authorships[1].institutions[2].country_code | SI |
| authorships[1].institutions[2].display_name | University Clinical Centre Maribor |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Monika Sobocan |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK, Divison for Gynaecology and Perinatology, University Medical Centre Maribor, 2000 Maribor, Slovenia, Wolfson Institute of Population Health, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK |
| authorships[2].author.id | https://openalex.org/A5038382199 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-0194-6389 |
| authorships[2].author.display_name | Oleg Blyuss |
| authorships[2].countries | GB, RU |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I17877952 |
| authorships[2].affiliations[0].raw_affiliation_string | Department of Paediatrics and Paediatric Infectious Diseases, Sechenov First Moscow State Medical University, Moscow 119991, Russia |
| authorships[2].affiliations[1].institution_ids | https://openalex.org/I141584323 |
| authorships[2].affiliations[1].raw_affiliation_string | School of Physics, Engineering and Computer Science, University of Hertfordshire, Hatfield AL10 9AB, UK |
| authorships[2].affiliations[2].institution_ids | https://openalex.org/I17877952 |
| authorships[2].affiliations[2].raw_affiliation_string | World-Class Research Center "Digital Biodesign and Personalized Healthcare", Sechenov First Moscow State Medical University, Moscow 119991, Russia |
| authorships[2].institutions[0].id | https://openalex.org/I141584323 |
| authorships[2].institutions[0].ror | https://ror.org/0267vjk41 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I141584323 |
| authorships[2].institutions[0].country_code | GB |
| authorships[2].institutions[0].display_name | University of Hertfordshire |
| authorships[2].institutions[1].id | https://openalex.org/I17877952 |
| authorships[2].institutions[1].ror | https://ror.org/02yqqv993 |
| authorships[2].institutions[1].type | education |
| authorships[2].institutions[1].lineage | https://openalex.org/I17877952 |
| authorships[2].institutions[1].country_code | RU |
| authorships[2].institutions[1].display_name | Sechenov University |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Oleg Blyuss |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Department of Paediatrics and Paediatric Infectious Diseases, Sechenov First Moscow State Medical University, Moscow 119991, Russia, School of Physics, Engineering and Computer Science, University of Hertfordshire, Hatfield AL10 9AB, UK, World-Class Research Center "Digital Biodesign and Personalized Healthcare", Sechenov First Moscow State Medical University, Moscow 119991, Russia |
| authorships[3].author.id | https://openalex.org/A5064459524 |
| authorships[3].author.orcid | https://orcid.org/0000-0002-2400-1716 |
| authorships[3].author.display_name | Rowan Miller |
| authorships[3].countries | GB |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I225661044 |
| authorships[3].affiliations[0].raw_affiliation_string | Department of Medical Oncology, Barts Health NHS Trust, London EC1A 7BE, UK |
| authorships[3].institutions[0].id | https://openalex.org/I225661044 |
| authorships[3].institutions[0].ror | https://ror.org/00b31g692 |
| authorships[3].institutions[0].type | healthcare |
| authorships[3].institutions[0].lineage | https://openalex.org/I225661044 |
| authorships[3].institutions[0].country_code | GB |
| authorships[3].institutions[0].display_name | Barts Health NHS Trust |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Rowan E. Miller |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Department of Medical Oncology, Barts Health NHS Trust, London EC1A 7BE, UK |
| authorships[4].author.id | https://openalex.org/A5102883010 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-8012-4964 |
| authorships[4].author.display_name | Olivia Evans |
| authorships[4].countries | GB |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I166337079 |
| authorships[4].affiliations[0].raw_affiliation_string | Wolfson Institute of Population Health, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK |
| authorships[4].institutions[0].id | https://openalex.org/I166337079 |
| authorships[4].institutions[0].ror | https://ror.org/026zzn846 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I124357947, https://openalex.org/I166337079 |
| authorships[4].institutions[0].country_code | GB |
| authorships[4].institutions[0].display_name | Queen Mary University of London |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Olivia Evans |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Wolfson Institute of Population Health, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK |
| authorships[5].author.id | https://openalex.org/A5053475330 |
| authorships[5].author.orcid | https://orcid.org/0000-0003-0687-0149 |
| authorships[5].author.display_name | Shanthini Mary Crusz |
| authorships[5].countries | GB |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I225661044 |
| authorships[5].affiliations[0].raw_affiliation_string | Department of Medical Oncology, Barts Health NHS Trust, London EC1A 7BE, UK |
| authorships[5].institutions[0].id | https://openalex.org/I225661044 |
| authorships[5].institutions[0].ror | https://ror.org/00b31g692 |
| authorships[5].institutions[0].type | healthcare |
| authorships[5].institutions[0].lineage | https://openalex.org/I225661044 |
| authorships[5].institutions[0].country_code | GB |
| authorships[5].institutions[0].display_name | Barts Health NHS Trust |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Shanthini M. Crusz |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Department of Medical Oncology, Barts Health NHS Trust, London EC1A 7BE, UK |
| authorships[6].author.id | https://openalex.org/A5004127738 |
| authorships[6].author.orcid | https://orcid.org/0000-0002-8787-0353 |
| authorships[6].author.display_name | Tina Mills‐Baldock |
| authorships[6].countries | GB |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I1293052470 |
| authorships[6].affiliations[0].raw_affiliation_string | Department of Medical Oncology, Barking, Havering & Redbridge University Hospitals, Essex RM7 0AG, UK |
| authorships[6].institutions[0].id | https://openalex.org/I1293052470 |
| authorships[6].institutions[0].ror | https://ror.org/03xnr5143 |
| authorships[6].institutions[0].type | healthcare |
| authorships[6].institutions[0].lineage | https://openalex.org/I1293052470 |
| authorships[6].institutions[0].country_code | GB |
| authorships[6].institutions[0].display_name | Barking, Havering And Redbridge University Hospitals NHS Trust |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Tina Mills-Baldock |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Department of Medical Oncology, Barking, Havering & Redbridge University Hospitals, Essex RM7 0AG, UK |
| authorships[7].author.id | https://openalex.org/A5009728920 |
| authorships[7].author.orcid | https://orcid.org/0000-0001-5569-7296 |
| authorships[7].author.display_name | Li Sun |
| authorships[7].countries | GB |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I4210089966, https://openalex.org/I4210120717 |
| authorships[7].affiliations[0].raw_affiliation_string | Department of Health Services Research, Faculty of Public Health & Policy, London School of Hygiene & Tropical Medicine, London WC1H 9SH, UK |
| authorships[7].affiliations[1].institution_ids | https://openalex.org/I166337079 |
| authorships[7].affiliations[1].raw_affiliation_string | Wolfson Institute of Population Health, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK |
| authorships[7].institutions[0].id | https://openalex.org/I4210120717 |
| authorships[7].institutions[0].ror | https://ror.org/01zqv1s26 |
| authorships[7].institutions[0].type | nonprofit |
| authorships[7].institutions[0].lineage | https://openalex.org/I4210120717 |
| authorships[7].institutions[0].country_code | GB |
| authorships[7].institutions[0].display_name | Faculty of Public Health |
| authorships[7].institutions[1].id | https://openalex.org/I4210089966 |
| authorships[7].institutions[1].ror | https://ror.org/00a0jsq62 |
| authorships[7].institutions[1].type | education |
| authorships[7].institutions[1].lineage | https://openalex.org/I124357947, https://openalex.org/I4210089966 |
| authorships[7].institutions[1].country_code | GB |
| authorships[7].institutions[1].display_name | London School of Hygiene & Tropical Medicine |
| authorships[7].institutions[2].id | https://openalex.org/I166337079 |
| authorships[7].institutions[2].ror | https://ror.org/026zzn846 |
| authorships[7].institutions[2].type | education |
| authorships[7].institutions[2].lineage | https://openalex.org/I124357947, https://openalex.org/I166337079 |
| authorships[7].institutions[2].country_code | GB |
| authorships[7].institutions[2].display_name | Queen Mary University of London |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Li Sun |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Department of Health Services Research, Faculty of Public Health & Policy, London School of Hygiene & Tropical Medicine, London WC1H 9SH, UK, Wolfson Institute of Population Health, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK |
| authorships[8].author.id | https://openalex.org/A5038675452 |
| authorships[8].author.orcid | https://orcid.org/0000-0002-0739-0537 |
| authorships[8].author.display_name | Rory F.L. Hammond |
| authorships[8].countries | GB |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I225661044 |
| authorships[8].affiliations[0].raw_affiliation_string | Department of Pathology, Barts Health NHS Trust, London E1 1FR, UK |
| authorships[8].institutions[0].id | https://openalex.org/I225661044 |
| authorships[8].institutions[0].ror | https://ror.org/00b31g692 |
| authorships[8].institutions[0].type | healthcare |
| authorships[8].institutions[0].lineage | https://openalex.org/I225661044 |
| authorships[8].institutions[0].country_code | GB |
| authorships[8].institutions[0].display_name | Barts Health NHS Trust |
| authorships[8].author_position | middle |
| authorships[8].raw_author_name | Rory F. L. Hammond |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | Department of Pathology, Barts Health NHS Trust, London E1 1FR, UK |
| authorships[9].author.id | https://openalex.org/A5022324670 |
| authorships[9].author.orcid | https://orcid.org/0000-0003-4081-6883 |
| authorships[9].author.display_name | Faiza Gaba |
| authorships[9].countries | GB |
| authorships[9].affiliations[0].institution_ids | https://openalex.org/I166337079 |
| authorships[9].affiliations[0].raw_affiliation_string | Wolfson Institute of Population Health, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK |
| authorships[9].institutions[0].id | https://openalex.org/I166337079 |
| authorships[9].institutions[0].ror | https://ror.org/026zzn846 |
| authorships[9].institutions[0].type | education |
| authorships[9].institutions[0].lineage | https://openalex.org/I124357947, https://openalex.org/I166337079 |
| authorships[9].institutions[0].country_code | GB |
| authorships[9].institutions[0].display_name | Queen Mary University of London |
| authorships[9].author_position | middle |
| authorships[9].raw_author_name | Faiza Gaba |
| authorships[9].is_corresponding | False |
| authorships[9].raw_affiliation_strings | Wolfson Institute of Population Health, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK |
| authorships[10].author.id | https://openalex.org/A5113834578 |
| authorships[10].author.orcid | |
| authorships[10].author.display_name | Lucy Jenkins |
| authorships[10].countries | GB |
| authorships[10].affiliations[0].institution_ids | https://openalex.org/I2800129641, https://openalex.org/I45129253 |
| authorships[10].affiliations[0].raw_affiliation_string | North East Thames Regional Genetics Service, Great Ormond Street Hospital, London WC1N 3JH, UK |
| authorships[10].institutions[0].id | https://openalex.org/I2800129641 |
| authorships[10].institutions[0].ror | https://ror.org/00zn2c847 |
| authorships[10].institutions[0].type | healthcare |
| authorships[10].institutions[0].lineage | https://openalex.org/I2800129641, https://openalex.org/I2800349819 |
| authorships[10].institutions[0].country_code | GB |
| authorships[10].institutions[0].display_name | Great Ormond Street Hospital |
| authorships[10].institutions[1].id | https://openalex.org/I45129253 |
| authorships[10].institutions[1].ror | https://ror.org/02jx3x895 |
| authorships[10].institutions[1].type | education |
| authorships[10].institutions[1].lineage | https://openalex.org/I124357947, https://openalex.org/I45129253 |
| authorships[10].institutions[1].country_code | GB |
| authorships[10].institutions[1].display_name | University College London |
| authorships[10].author_position | middle |
| authorships[10].raw_author_name | Lucy A. Jenkins |
| authorships[10].is_corresponding | False |
| authorships[10].raw_affiliation_strings | North East Thames Regional Genetics Service, Great Ormond Street Hospital, London WC1N 3JH, UK |
| authorships[11].author.id | https://openalex.org/A5101138651 |
| authorships[11].author.orcid | |
| authorships[11].author.display_name | Munaza Ahmed |
| authorships[11].countries | GB |
| authorships[11].affiliations[0].institution_ids | https://openalex.org/I2800129641, https://openalex.org/I45129253 |
| authorships[11].affiliations[0].raw_affiliation_string | North East Thames Regional Genetics Service, Great Ormond Street Hospital, London WC1N 3JH, UK |
| authorships[11].institutions[0].id | https://openalex.org/I2800129641 |
| authorships[11].institutions[0].ror | https://ror.org/00zn2c847 |
| authorships[11].institutions[0].type | healthcare |
| authorships[11].institutions[0].lineage | https://openalex.org/I2800129641, https://openalex.org/I2800349819 |
| authorships[11].institutions[0].country_code | GB |
| authorships[11].institutions[0].display_name | Great Ormond Street Hospital |
| authorships[11].institutions[1].id | https://openalex.org/I45129253 |
| authorships[11].institutions[1].ror | https://ror.org/02jx3x895 |
| authorships[11].institutions[1].type | education |
| authorships[11].institutions[1].lineage | https://openalex.org/I124357947, https://openalex.org/I45129253 |
| authorships[11].institutions[1].country_code | GB |
| authorships[11].institutions[1].display_name | University College London |
| authorships[11].author_position | middle |
| authorships[11].raw_author_name | Munaza Ahmed |
| authorships[11].is_corresponding | False |
| authorships[11].raw_affiliation_strings | North East Thames Regional Genetics Service, Great Ormond Street Hospital, London WC1N 3JH, UK |
| authorships[12].author.id | https://openalex.org/A5065445608 |
| authorships[12].author.orcid | https://orcid.org/0000-0003-3878-2856 |
| authorships[12].author.display_name | Ajith Kumar |
| authorships[12].countries | GB |
| authorships[12].affiliations[0].institution_ids | https://openalex.org/I2800129641, https://openalex.org/I45129253 |
| authorships[12].affiliations[0].raw_affiliation_string | North East Thames Regional Genetics Service, Great Ormond Street Hospital, London WC1N 3JH, UK |
| authorships[12].institutions[0].id | https://openalex.org/I2800129641 |
| authorships[12].institutions[0].ror | https://ror.org/00zn2c847 |
| authorships[12].institutions[0].type | healthcare |
| authorships[12].institutions[0].lineage | https://openalex.org/I2800129641, https://openalex.org/I2800349819 |
| authorships[12].institutions[0].country_code | GB |
| authorships[12].institutions[0].display_name | Great Ormond Street Hospital |
| authorships[12].institutions[1].id | https://openalex.org/I45129253 |
| authorships[12].institutions[1].ror | https://ror.org/02jx3x895 |
| authorships[12].institutions[1].type | education |
| authorships[12].institutions[1].lineage | https://openalex.org/I124357947, https://openalex.org/I45129253 |
| authorships[12].institutions[1].country_code | GB |
| authorships[12].institutions[1].display_name | University College London |
| authorships[12].author_position | middle |
| authorships[12].raw_author_name | Ajith Kumar |
| authorships[12].is_corresponding | False |
| authorships[12].raw_affiliation_strings | North East Thames Regional Genetics Service, Great Ormond Street Hospital, London WC1N 3JH, UK |
| authorships[13].author.id | https://openalex.org/A5040185556 |
| authorships[13].author.orcid | |
| authorships[13].author.display_name | Arjun Jeyarajah |
| authorships[13].countries | GB |
| authorships[13].affiliations[0].institution_ids | https://openalex.org/I225661044 |
| authorships[13].affiliations[0].raw_affiliation_string | Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK |
| authorships[13].institutions[0].id | https://openalex.org/I225661044 |
| authorships[13].institutions[0].ror | https://ror.org/00b31g692 |
| authorships[13].institutions[0].type | healthcare |
| authorships[13].institutions[0].lineage | https://openalex.org/I225661044 |
| authorships[13].institutions[0].country_code | GB |
| authorships[13].institutions[0].display_name | Barts Health NHS Trust |
| authorships[13].author_position | middle |
| authorships[13].raw_author_name | Arjun Jeyarajah |
| authorships[13].is_corresponding | False |
| authorships[13].raw_affiliation_strings | Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK |
| authorships[14].author.id | https://openalex.org/A5032434810 |
| authorships[14].author.orcid | https://orcid.org/0000-0002-8911-4252 |
| authorships[14].author.display_name | Alexandra Lawrence |
| authorships[14].countries | GB |
| authorships[14].affiliations[0].institution_ids | https://openalex.org/I225661044 |
| authorships[14].affiliations[0].raw_affiliation_string | Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK |
| authorships[14].institutions[0].id | https://openalex.org/I225661044 |
| authorships[14].institutions[0].ror | https://ror.org/00b31g692 |
| authorships[14].institutions[0].type | healthcare |
| authorships[14].institutions[0].lineage | https://openalex.org/I225661044 |
| authorships[14].institutions[0].country_code | GB |
| authorships[14].institutions[0].display_name | Barts Health NHS Trust |
| authorships[14].author_position | middle |
| authorships[14].raw_author_name | Alexandra C. Lawrence |
| authorships[14].is_corresponding | False |
| authorships[14].raw_affiliation_strings | Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK |
| authorships[15].author.id | https://openalex.org/A5084052846 |
| authorships[15].author.orcid | |
| authorships[15].author.display_name | Elly Brockbank |
| authorships[15].countries | GB |
| authorships[15].affiliations[0].institution_ids | https://openalex.org/I225661044 |
| authorships[15].affiliations[0].raw_affiliation_string | Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK |
| authorships[15].institutions[0].id | https://openalex.org/I225661044 |
| authorships[15].institutions[0].ror | https://ror.org/00b31g692 |
| authorships[15].institutions[0].type | healthcare |
| authorships[15].institutions[0].lineage | https://openalex.org/I225661044 |
| authorships[15].institutions[0].country_code | GB |
| authorships[15].institutions[0].display_name | Barts Health NHS Trust |
| authorships[15].author_position | middle |
| authorships[15].raw_author_name | Elly Brockbank |
| authorships[15].is_corresponding | False |
| authorships[15].raw_affiliation_strings | Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK |
| authorships[16].author.id | https://openalex.org/A5018313663 |
| authorships[16].author.orcid | https://orcid.org/0000-0002-0959-3514 |
| authorships[16].author.display_name | Saurabh Phadnis |
| authorships[16].countries | GB |
| authorships[16].affiliations[0].institution_ids | https://openalex.org/I225661044 |
| authorships[16].affiliations[0].raw_affiliation_string | Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK |
| authorships[16].institutions[0].id | https://openalex.org/I225661044 |
| authorships[16].institutions[0].ror | https://ror.org/00b31g692 |
| authorships[16].institutions[0].type | healthcare |
| authorships[16].institutions[0].lineage | https://openalex.org/I225661044 |
| authorships[16].institutions[0].country_code | GB |
| authorships[16].institutions[0].display_name | Barts Health NHS Trust |
| authorships[16].author_position | middle |
| authorships[16].raw_author_name | Saurabh Phadnis |
| authorships[16].is_corresponding | False |
| authorships[16].raw_affiliation_strings | Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK |
| authorships[17].author.id | https://openalex.org/A5030149834 |
| authorships[17].author.orcid | |
| authorships[17].author.display_name | Mary Quigley |
| authorships[17].countries | GB |
| authorships[17].affiliations[0].institution_ids | https://openalex.org/I1293052470 |
| authorships[17].affiliations[0].raw_affiliation_string | Department of Medical Oncology, Barking, Havering & Redbridge University Hospitals, Essex RM7 0AG, UK |
| authorships[17].institutions[0].id | https://openalex.org/I1293052470 |
| authorships[17].institutions[0].ror | https://ror.org/03xnr5143 |
| authorships[17].institutions[0].type | healthcare |
| authorships[17].institutions[0].lineage | https://openalex.org/I1293052470 |
| authorships[17].institutions[0].country_code | GB |
| authorships[17].institutions[0].display_name | Barking, Havering And Redbridge University Hospitals NHS Trust |
| authorships[17].author_position | middle |
| authorships[17].raw_author_name | Mary Quigley |
| authorships[17].is_corresponding | False |
| authorships[17].raw_affiliation_strings | Department of Medical Oncology, Barking, Havering & Redbridge University Hospitals, Essex RM7 0AG, UK |
| authorships[18].author.id | https://openalex.org/A5072621609 |
| authorships[18].author.orcid | |
| authorships[18].author.display_name | Fatima El Khouly |
| authorships[18].countries | GB |
| authorships[18].affiliations[0].institution_ids | https://openalex.org/I1293052470 |
| authorships[18].affiliations[0].raw_affiliation_string | Department of Medical Oncology, Barking, Havering & Redbridge University Hospitals, Essex RM7 0AG, UK |
| authorships[18].institutions[0].id | https://openalex.org/I1293052470 |
| authorships[18].institutions[0].ror | https://ror.org/03xnr5143 |
| authorships[18].institutions[0].type | healthcare |
| authorships[18].institutions[0].lineage | https://openalex.org/I1293052470 |
| authorships[18].institutions[0].country_code | GB |
| authorships[18].institutions[0].display_name | Barking, Havering And Redbridge University Hospitals NHS Trust |
| authorships[18].author_position | middle |
| authorships[18].raw_author_name | Fatima El Khouly |
| authorships[18].is_corresponding | False |
| authorships[18].raw_affiliation_strings | Department of Medical Oncology, Barking, Havering & Redbridge University Hospitals, Essex RM7 0AG, UK |
| authorships[19].author.id | https://openalex.org/A5083785386 |
| authorships[19].author.orcid | |
| authorships[19].author.display_name | Rekha Wuntakal |
| authorships[19].countries | GB |
| authorships[19].affiliations[0].institution_ids | https://openalex.org/I1293052470 |
| authorships[19].affiliations[0].raw_affiliation_string | Department of Gynaecology, Barking, Havering & Redbridge University Hospitals, Essex RM7 0AG, UK |
| authorships[19].institutions[0].id | https://openalex.org/I1293052470 |
| authorships[19].institutions[0].ror | https://ror.org/03xnr5143 |
| authorships[19].institutions[0].type | healthcare |
| authorships[19].institutions[0].lineage | https://openalex.org/I1293052470 |
| authorships[19].institutions[0].country_code | GB |
| authorships[19].institutions[0].display_name | Barking, Havering And Redbridge University Hospitals NHS Trust |
| authorships[19].author_position | middle |
| authorships[19].raw_author_name | Rekha Wuntakal |
| authorships[19].is_corresponding | False |
| authorships[19].raw_affiliation_strings | Department of Gynaecology, Barking, Havering & Redbridge University Hospitals, Essex RM7 0AG, UK |
| authorships[20].author.id | https://openalex.org/A5012790591 |
| authorships[20].author.orcid | |
| authorships[20].author.display_name | Asma Faruqi |
| authorships[20].countries | GB |
| authorships[20].affiliations[0].institution_ids | https://openalex.org/I225661044 |
| authorships[20].affiliations[0].raw_affiliation_string | Department of Pathology, Barts Health NHS Trust, London E1 1FR, UK |
| authorships[20].institutions[0].id | https://openalex.org/I225661044 |
| authorships[20].institutions[0].ror | https://ror.org/00b31g692 |
| authorships[20].institutions[0].type | healthcare |
| authorships[20].institutions[0].lineage | https://openalex.org/I225661044 |
| authorships[20].institutions[0].country_code | GB |
| authorships[20].institutions[0].display_name | Barts Health NHS Trust |
| authorships[20].author_position | middle |
| authorships[20].raw_author_name | Asma Faruqi |
| authorships[20].is_corresponding | False |
| authorships[20].raw_affiliation_strings | Department of Pathology, Barts Health NHS Trust, London E1 1FR, UK |
| authorships[21].author.id | https://openalex.org/A5103626994 |
| authorships[21].author.orcid | |
| authorships[21].author.display_name | Giorgia Trevisan |
| authorships[21].countries | GB |
| authorships[21].affiliations[0].institution_ids | https://openalex.org/I225661044 |
| authorships[21].affiliations[0].raw_affiliation_string | Department of Pathology, Barts Health NHS Trust, London E1 1FR, UK |
| authorships[21].institutions[0].id | https://openalex.org/I225661044 |
| authorships[21].institutions[0].ror | https://ror.org/00b31g692 |
| authorships[21].institutions[0].type | healthcare |
| authorships[21].institutions[0].lineage | https://openalex.org/I225661044 |
| authorships[21].institutions[0].country_code | GB |
| authorships[21].institutions[0].display_name | Barts Health NHS Trust |
| authorships[21].author_position | middle |
| authorships[21].raw_author_name | Giorgia Trevisan |
| authorships[21].is_corresponding | False |
| authorships[21].raw_affiliation_strings | Department of Pathology, Barts Health NHS Trust, London E1 1FR, UK |
| authorships[22].author.id | https://openalex.org/A5004441171 |
| authorships[22].author.orcid | https://orcid.org/0000-0001-6548-4470 |
| authorships[22].author.display_name | Laura Casey |
| authorships[22].countries | GB |
| authorships[22].affiliations[0].institution_ids | https://openalex.org/I225661044 |
| authorships[22].affiliations[0].raw_affiliation_string | Department of Pathology, Barts Health NHS Trust, London E1 1FR, UK |
| authorships[22].institutions[0].id | https://openalex.org/I225661044 |
| authorships[22].institutions[0].ror | https://ror.org/00b31g692 |
| authorships[22].institutions[0].type | healthcare |
| authorships[22].institutions[0].lineage | https://openalex.org/I225661044 |
| authorships[22].institutions[0].country_code | GB |
| authorships[22].institutions[0].display_name | Barts Health NHS Trust |
| authorships[22].author_position | middle |
| authorships[22].raw_author_name | Laura Casey |
| authorships[22].is_corresponding | False |
| authorships[22].raw_affiliation_strings | Department of Pathology, Barts Health NHS Trust, London E1 1FR, UK |
| authorships[23].author.id | https://openalex.org/A5065233337 |
| authorships[23].author.orcid | https://orcid.org/0000-0001-9360-8194 |
| authorships[23].author.display_name | George J. Burghel |
| authorships[23].affiliations[0].raw_affiliation_string | Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK |
| authorships[23].author_position | middle |
| authorships[23].raw_author_name | George J. Burghel |
| authorships[23].is_corresponding | False |
| authorships[23].raw_affiliation_strings | Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK |
| authorships[24].author.id | https://openalex.org/A5085294181 |
| authorships[24].author.orcid | https://orcid.org/0000-0002-1916-6575 |
| authorships[24].author.display_name | Hélene Schlecht |
| authorships[24].affiliations[0].raw_affiliation_string | Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK |
| authorships[24].author_position | middle |
| authorships[24].raw_author_name | Helene Schlecht |
| authorships[24].is_corresponding | False |
| authorships[24].raw_affiliation_strings | Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK |
| authorships[25].author.id | https://openalex.org/A5109075497 |
| authorships[25].author.orcid | |
| authorships[25].author.display_name | Michael Bulman |
| authorships[25].affiliations[0].raw_affiliation_string | Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK |
| authorships[25].author_position | middle |
| authorships[25].raw_author_name | Michael Bulman |
| authorships[25].is_corresponding | False |
| authorships[25].raw_affiliation_strings | Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK |
| authorships[26].author.id | https://openalex.org/A5016531852 |
| authorships[26].author.orcid | https://orcid.org/0000-0002-6369-3719 |
| authorships[26].author.display_name | Philip Smith |
| authorships[26].affiliations[0].raw_affiliation_string | Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK |
| authorships[26].author_position | middle |
| authorships[26].raw_author_name | Philip Smith |
| authorships[26].is_corresponding | False |
| authorships[26].raw_affiliation_strings | Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK |
| authorships[27].author.id | https://openalex.org/A5051212071 |
| authorships[27].author.orcid | |
| authorships[27].author.display_name | Naomi L. Bowers |
| authorships[27].affiliations[0].raw_affiliation_string | Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK |
| authorships[27].author_position | middle |
| authorships[27].raw_author_name | Naomi L. Bowers |
| authorships[27].is_corresponding | False |
| authorships[27].raw_affiliation_strings | Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK |
| authorships[28].author.id | https://openalex.org/A5061826468 |
| authorships[28].author.orcid | https://orcid.org/0000-0003-2761-5227 |
| authorships[28].author.display_name | Rosa Legood |
| authorships[28].countries | GB |
| authorships[28].affiliations[0].institution_ids | https://openalex.org/I4210089966, https://openalex.org/I4210120717 |
| authorships[28].affiliations[0].raw_affiliation_string | Department of Health Services Research, Faculty of Public Health & Policy, London School of Hygiene & Tropical Medicine, London WC1H 9SH, UK |
| authorships[28].institutions[0].id | https://openalex.org/I4210120717 |
| authorships[28].institutions[0].ror | https://ror.org/01zqv1s26 |
| authorships[28].institutions[0].type | nonprofit |
| authorships[28].institutions[0].lineage | https://openalex.org/I4210120717 |
| authorships[28].institutions[0].country_code | GB |
| authorships[28].institutions[0].display_name | Faculty of Public Health |
| authorships[28].institutions[1].id | https://openalex.org/I4210089966 |
| authorships[28].institutions[1].ror | https://ror.org/00a0jsq62 |
| authorships[28].institutions[1].type | education |
| authorships[28].institutions[1].lineage | https://openalex.org/I124357947, https://openalex.org/I4210089966 |
| authorships[28].institutions[1].country_code | GB |
| authorships[28].institutions[1].display_name | London School of Hygiene & Tropical Medicine |
| authorships[28].author_position | middle |
| authorships[28].raw_author_name | Rosa Legood |
| authorships[28].is_corresponding | False |
| authorships[28].raw_affiliation_strings | Department of Health Services Research, Faculty of Public Health & Policy, London School of Hygiene & Tropical Medicine, London WC1H 9SH, UK |
| authorships[29].author.id | https://openalex.org/A5035831323 |
| authorships[29].author.orcid | https://orcid.org/0000-0002-9281-5789 |
| authorships[29].author.display_name | Michelle Lockley |
| authorships[29].countries | GB |
| authorships[29].affiliations[0].institution_ids | https://openalex.org/I166337079 |
| authorships[29].affiliations[0].raw_affiliation_string | Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK |
| authorships[29].institutions[0].id | https://openalex.org/I166337079 |
| authorships[29].institutions[0].ror | https://ror.org/026zzn846 |
| authorships[29].institutions[0].type | education |
| authorships[29].institutions[0].lineage | https://openalex.org/I124357947, https://openalex.org/I166337079 |
| authorships[29].institutions[0].country_code | GB |
| authorships[29].institutions[0].display_name | Queen Mary University of London |
| authorships[29].author_position | middle |
| authorships[29].raw_author_name | Michelle Lockley |
| authorships[29].is_corresponding | False |
| authorships[29].raw_affiliation_strings | Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK |
| authorships[30].author.id | https://openalex.org/A5066680610 |
| authorships[30].author.orcid | https://orcid.org/0000-0002-9603-8892 |
| authorships[30].author.display_name | Andrew J. Wallace |
| authorships[30].affiliations[0].raw_affiliation_string | Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK |
| authorships[30].author_position | middle |
| authorships[30].raw_author_name | Andrew Wallace |
| authorships[30].is_corresponding | False |
| authorships[30].raw_affiliation_strings | Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK |
| authorships[31].author.id | https://openalex.org/A5084183460 |
| authorships[31].author.orcid | https://orcid.org/0000-0003-1782-1967 |
| authorships[31].author.display_name | Naveena Singh |
| authorships[31].countries | GB |
| authorships[31].affiliations[0].institution_ids | https://openalex.org/I225661044 |
| authorships[31].affiliations[0].raw_affiliation_string | Department of Pathology, Barts Health NHS Trust, London E1 1FR, UK |
| authorships[31].institutions[0].id | https://openalex.org/I225661044 |
| authorships[31].institutions[0].ror | https://ror.org/00b31g692 |
| authorships[31].institutions[0].type | healthcare |
| authorships[31].institutions[0].lineage | https://openalex.org/I225661044 |
| authorships[31].institutions[0].country_code | GB |
| authorships[31].institutions[0].display_name | Barts Health NHS Trust |
| authorships[31].author_position | middle |
| authorships[31].raw_author_name | Naveena Singh |
| authorships[31].is_corresponding | False |
| authorships[31].raw_affiliation_strings | Department of Pathology, Barts Health NHS Trust, London E1 1FR, UK |
| authorships[32].author.id | https://openalex.org/A5087003938 |
| authorships[32].author.orcid | https://orcid.org/0000-0002-8482-5784 |
| authorships[32].author.display_name | D. Gareth Evans |
| authorships[32].affiliations[0].raw_affiliation_string | Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK |
| authorships[32].author_position | middle |
| authorships[32].raw_author_name | D. Gareth Evans |
| authorships[32].is_corresponding | False |
| authorships[32].raw_affiliation_strings | Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK |
| authorships[33].author.id | https://openalex.org/A5027945638 |
| authorships[33].author.orcid | https://orcid.org/0000-0003-3381-5057 |
| authorships[33].author.display_name | Ranjit Manchanda |
| authorships[33].countries | GB |
| authorships[33].affiliations[0].institution_ids | https://openalex.org/I166337079 |
| authorships[33].affiliations[0].raw_affiliation_string | Wolfson Institute of Population Health, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK |
| authorships[33].affiliations[1].institution_ids | https://openalex.org/I225661044 |
| authorships[33].affiliations[1].raw_affiliation_string | Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK |
| authorships[33].affiliations[2].institution_ids | https://openalex.org/I4210089966, https://openalex.org/I4210120717 |
| authorships[33].affiliations[2].raw_affiliation_string | Department of Health Services Research, Faculty of Public Health & Policy, London School of Hygiene & Tropical Medicine, London WC1H 9SH, UK |
| authorships[33].institutions[0].id | https://openalex.org/I225661044 |
| authorships[33].institutions[0].ror | https://ror.org/00b31g692 |
| authorships[33].institutions[0].type | healthcare |
| authorships[33].institutions[0].lineage | https://openalex.org/I225661044 |
| authorships[33].institutions[0].country_code | GB |
| authorships[33].institutions[0].display_name | Barts Health NHS Trust |
| authorships[33].institutions[1].id | https://openalex.org/I4210120717 |
| authorships[33].institutions[1].ror | https://ror.org/01zqv1s26 |
| authorships[33].institutions[1].type | nonprofit |
| authorships[33].institutions[1].lineage | https://openalex.org/I4210120717 |
| authorships[33].institutions[1].country_code | GB |
| authorships[33].institutions[1].display_name | Faculty of Public Health |
| authorships[33].institutions[2].id | https://openalex.org/I4210089966 |
| authorships[33].institutions[2].ror | https://ror.org/00a0jsq62 |
| authorships[33].institutions[2].type | education |
| authorships[33].institutions[2].lineage | https://openalex.org/I124357947, https://openalex.org/I4210089966 |
| authorships[33].institutions[2].country_code | GB |
| authorships[33].institutions[2].display_name | London School of Hygiene & Tropical Medicine |
| authorships[33].institutions[3].id | https://openalex.org/I166337079 |
| authorships[33].institutions[3].ror | https://ror.org/026zzn846 |
| authorships[33].institutions[3].type | education |
| authorships[33].institutions[3].lineage | https://openalex.org/I124357947, https://openalex.org/I166337079 |
| authorships[33].institutions[3].country_code | GB |
| authorships[33].institutions[3].display_name | Queen Mary University of London |
| authorships[33].author_position | last |
| authorships[33].raw_author_name | Ranjit Manchanda |
| authorships[33].is_corresponding | True |
| authorships[33].raw_affiliation_strings | Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK, Department of Health Services Research, Faculty of Public Health & Policy, London School of Hygiene & Tropical Medicine, London WC1H 9SH, UK, Wolfson Institute of Population Health, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.mdpi.com/2072-6694/13/17/4344/pdf?version=1630291414 |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Implementation of Multigene Germline and Parallel Somatic Genetic Testing in Epithelial Ovarian Cancer: SIGNPOST Study |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10769 |
| primary_topic.field.id | https://openalex.org/fields/13 |
| primary_topic.field.display_name | Biochemistry, Genetics and Molecular Biology |
| primary_topic.score | 0.9998999834060669 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/1311 |
| primary_topic.subfield.display_name | Genetics |
| primary_topic.display_name | BRCA gene mutations in cancer |
| related_works | https://openalex.org/W2606201227, https://openalex.org/W2000783020, https://openalex.org/W2086399984, https://openalex.org/W1491598325, https://openalex.org/W2310082378, https://openalex.org/W3026290368, https://openalex.org/W2093846964, https://openalex.org/W4238761868, https://openalex.org/W4296060409, https://openalex.org/W2041452721 |
| cited_by_count | 49 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 9 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 15 |
| counts_by_year[2].year | 2023 |
| counts_by_year[2].cited_by_count | 10 |
| counts_by_year[3].year | 2022 |
| counts_by_year[3].cited_by_count | 15 |
| locations_count | 10 |
| best_oa_location.id | doi:10.3390/cancers13174344 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S168415115 |
| best_oa_location.source.issn | 2072-6694 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 2072-6694 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | Cancers |
| best_oa_location.source.host_organization | https://openalex.org/P4310310987 |
| best_oa_location.source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310310987 |
| best_oa_location.source.host_organization_lineage_names | Multidisciplinary Digital Publishing Institute |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | https://www.mdpi.com/2072-6694/13/17/4344/pdf?version=1630291414 |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Cancers |
| best_oa_location.landing_page_url | https://doi.org/10.3390/cancers13174344 |
| primary_location.id | doi:10.3390/cancers13174344 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S168415115 |
| primary_location.source.issn | 2072-6694 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 2072-6694 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Cancers |
| primary_location.source.host_organization | https://openalex.org/P4310310987 |
| primary_location.source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310310987 |
| primary_location.source.host_organization_lineage_names | Multidisciplinary Digital Publishing Institute |
| primary_location.license | cc-by |
| primary_location.pdf_url | https://www.mdpi.com/2072-6694/13/17/4344/pdf?version=1630291414 |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Cancers |
| primary_location.landing_page_url | https://doi.org/10.3390/cancers13174344 |
| publication_date | 2021-08-27 |
| publication_year | 2021 |
| referenced_works | https://openalex.org/W2060427373, https://openalex.org/W2627871710, https://openalex.org/W3155705538, https://openalex.org/W2130078242, https://openalex.org/W2897430921, https://openalex.org/W2754327139, https://openalex.org/W2737389832, https://openalex.org/W4210954872, https://openalex.org/W3001210504, https://openalex.org/W3124863637, https://openalex.org/W3089768241, https://openalex.org/W2772338061, https://openalex.org/W2325363292, https://openalex.org/W3007067759, https://openalex.org/W2968489008, https://openalex.org/W2137167442, https://openalex.org/W2132266605, https://openalex.org/W2147058464, https://openalex.org/W2099535971, https://openalex.org/W2463058287, https://openalex.org/W2379130638, https://openalex.org/W2744884535, https://openalex.org/W2745994405, https://openalex.org/W2938370698, https://openalex.org/W2624605816, https://openalex.org/W3006340694, https://openalex.org/W2053766582, https://openalex.org/W3008236638, https://openalex.org/W2793490667, https://openalex.org/W3042087634, https://openalex.org/W2028682388, https://openalex.org/W2792027007, https://openalex.org/W2224210111, https://openalex.org/W2404782822, https://openalex.org/W2989421973, https://openalex.org/W2003394553, https://openalex.org/W2152926599, https://openalex.org/W2080908201, https://openalex.org/W2982004045, https://openalex.org/W2889993776, https://openalex.org/W2140563000, https://openalex.org/W2894287803, https://openalex.org/W2088346456, https://openalex.org/W2509689465, https://openalex.org/W2113926943, https://openalex.org/W2116372322, https://openalex.org/W2151413771, https://openalex.org/W2035380441, https://openalex.org/W1591121676, https://openalex.org/W3139662153, https://openalex.org/W1971999164, https://openalex.org/W2955248454, https://openalex.org/W2989426757, https://openalex.org/W2808833299, https://openalex.org/W2936050191 |
| referenced_works_count | 55 |
| abstract_inverted_index.= | 91, 101, 107 |
| abstract_inverted_index.A | 126, 138, 146, 159 |
| abstract_inverted_index.a | 4, 46, 73, 197, 207, 224 |
| abstract_inverted_index.(p | 82, 106 |
| abstract_inverted_index.54 | 89 |
| abstract_inverted_index.61 | 99 |
| abstract_inverted_index.OC | 227 |
| abstract_inverted_index.UK | 215 |
| abstract_inverted_index.We | 0 |
| abstract_inverted_index.as | 206 |
| abstract_inverted_index.be | 220 |
| abstract_inverted_index.by | 45, 62, 118, 156, 167, 177 |
| abstract_inverted_index.in | 21, 94, 103, 114 |
| abstract_inverted_index.is | 186 |
| abstract_inverted_index.no | 111 |
| abstract_inverted_index.of | 3, 11, 52, 116, 128, 140, 148, 161, 226 |
| abstract_inverted_index.or | 77, 123 |
| abstract_inverted_index.to | 72, 211, 222 |
| abstract_inverted_index.11% | 149 |
| abstract_inverted_index.20% | 162 |
| abstract_inverted_index.MDT | 48 |
| abstract_inverted_index.Our | 194 |
| abstract_inverted_index.PVs | 117, 135, 151, 164, 175 |
| abstract_inverted_index.The | 50, 85, 181 |
| abstract_inverted_index.age | 87 |
| abstract_inverted_index.all | 22 |
| abstract_inverted_index.and | 16, 26, 32, 43, 56, 131, 154, 172, 201 |
| abstract_inverted_index.are | 165 |
| abstract_inverted_index.for | 189 |
| abstract_inverted_index.had | 143 |
| abstract_inverted_index.the | 28 |
| abstract_inverted_index.two | 37 |
| abstract_inverted_index.was | 59, 88, 110 |
| abstract_inverted_index.< | 83 |
| abstract_inverted_index.(IQR | 90, 100 |
| abstract_inverted_index.(PV) | 97 |
| abstract_inverted_index.2.3% | 141 |
| abstract_inverted_index.7.8% | 132 |
| abstract_inverted_index.BRCA | 104 |
| abstract_inverted_index.PVs. | 145 |
| abstract_inverted_index.more | 64 |
| abstract_inverted_index.rate | 185 |
| abstract_inverted_index.were | 41, 136, 152 |
| abstract_inverted_index.with | 24 |
| abstract_inverted_index.>1 | 67 |
| abstract_inverted_index.(23%) | 188 |
| abstract_inverted_index.(MDT) | 7 |
| abstract_inverted_index.15.5% | 129 |
| abstract_inverted_index.55.6% | 173 |
| abstract_inverted_index.There | 109 |
| abstract_inverted_index.first | 169 |
| abstract_inverted_index.panel | 203, 225 |
| abstract_inverted_index.total | 127, 139, 147, 160 |
| abstract_inverted_index.women | 23 |
| abstract_inverted_index.years | 93 |
| abstract_inverted_index.(15.0% | 75 |
| abstract_inverted_index.(15.3% | 80 |
| abstract_inverted_index.(53.6% | 69 |
| abstract_inverted_index.97.7%. | 60 |
| abstract_inverted_index.across | 36 |
| abstract_inverted_index.cancer | 5, 38, 47 |
| abstract_inverted_index.family | 178 |
| abstract_inverted_index.favour | 196 |
| abstract_inverted_index.genes. | 228 |
| abstract_inverted_index.higher | 187 |
| abstract_inverted_index.median | 86 |
| abstract_inverted_index.missed | 155, 166, 176 |
| abstract_inverted_index.needed | 66 |
| abstract_inverted_index.should | 219 |
| abstract_inverted_index.stage, | 120 |
| abstract_inverted_index.timing | 122 |
| abstract_inverted_index.uptake | 51 |
| abstract_inverted_index.versus | 98 |
| abstract_inverted_index.0.001). | 84, 108 |
| abstract_inverted_index.5-panel | 13 |
| abstract_inverted_index.between | 30 |
| abstract_inverted_index.failure | 184 |
| abstract_inverted_index.history | 179 |
| abstract_inverted_index.include | 223 |
| abstract_inverted_index.medical | 74 |
| abstract_inverted_index.member. | 49 |
| abstract_inverted_index.pathway | 10 |
| abstract_inverted_index.present | 1 |
| abstract_inverted_index.somatic | 18, 33, 57, 133, 157, 168, 182, 200 |
| abstract_inverted_index.status. | 125 |
| abstract_inverted_index.surgery | 121 |
| abstract_inverted_index.testing | 20, 34, 58, 183, 204 |
| abstract_inverted_index.variant | 213 |
| abstract_inverted_index.(30/56)) | 70 |
| abstract_inverted_index.51–62) | 92 |
| abstract_inverted_index.51–71) | 102 |
| abstract_inverted_index.Genomics | 216 |
| abstract_inverted_index.Patients | 40 |
| abstract_inverted_index.approach | 171, 205 |
| abstract_inverted_index.centres. | 39 |
| abstract_inverted_index.compared | 71 |
| abstract_inverted_index.criteria | 218 |
| abstract_inverted_index.expanded | 221 |
| abstract_inverted_index.findings | 2, 195 |
| abstract_inverted_index.germline | 14, 31, 55, 95, 130, 150, 163, 174, 202 |
| abstract_inverted_index.maximise | 212 |
| abstract_inverted_index.parallel | 17, 53, 199 |
| abstract_inverted_index.patients | 142, 190 |
| abstract_inverted_index.strategy | 210 |
| abstract_inverted_index.surgical | 78 |
| abstract_inverted_index.testing. | 158 |
| abstract_inverted_index.(17/110)) | 81 |
| abstract_inverted_index.(21/137)) | 76 |
| abstract_inverted_index.biopsies. | 193 |
| abstract_inverted_index.consented | 44 |
| abstract_inverted_index.efficient | 209 |
| abstract_inverted_index.highlight | 27 |
| abstract_inverted_index.resection | 124 |
| abstract_inverted_index.wild-type | 105 |
| abstract_inverted_index.clinically | 208 |
| abstract_inverted_index.counselled | 42 |
| abstract_inverted_index.diagnostic | 192 |
| abstract_inverted_index.difference | 113 |
| abstract_inverted_index.ethnicity, | 119 |
| abstract_inverted_index.frequently | 65 |
| abstract_inverted_index.multi-gene | 54 |
| abstract_inverted_index.oncologist | 79 |
| abstract_inverted_index.strategies | 35 |
| abstract_inverted_index.undergoing | 191 |
| abstract_inverted_index.unselected | 12 |
| abstract_inverted_index.BRCA1/BRCA2 | 19, 134 |
| abstract_inverted_index.Counselling | 61 |
| abstract_inverted_index.coordinated | 8 |
| abstract_inverted_index.discordance | 29 |
| abstract_inverted_index.identified. | 137 |
| abstract_inverted_index.prospective | 198 |
| abstract_inverted_index.significant | 112 |
| abstract_inverted_index.BRCA-testing | 170 |
| abstract_inverted_index.consultation | 68 |
| abstract_inverted_index.distribution | 115 |
| abstract_inverted_index.epithelial-OC | 25 |
| abstract_inverted_index.mainstreaming | 9 |
| abstract_inverted_index.ascertainment. | 180 |
| abstract_inverted_index.test-directory | 217 |
| abstract_inverted_index.identification. | 214 |
| abstract_inverted_index.pathogenic-variant | 96 |
| abstract_inverted_index.RAD51C/RAD51D/BRIP1 | 144 |
| abstract_inverted_index.multidisciplinary-team | 6 |
| abstract_inverted_index.clinical-nurse-specialist | 63 |
| abstract_inverted_index.large-genomic-rearrangements | 153 |
| abstract_inverted_index.BRCA1/BRCA2/RAD51C/RAD51D/BRIP1 | 15 |
| cited_by_percentile_year.max | 99 |
| cited_by_percentile_year.min | 98 |
| corresponding_author_ids | https://openalex.org/A5027945638 |
| countries_distinct_count | 3 |
| institutions_distinct_count | 34 |
| corresponding_institution_ids | https://openalex.org/I166337079, https://openalex.org/I225661044, https://openalex.org/I4210089966, https://openalex.org/I4210120717 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.5 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.97251273 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |