Myroxylon pereiraeresin (balsam of Peru) – A critical review of the literature and assessment of the significance of positive patch test reactions and the usefulness of restrictive diets Article Swipe
In this article, contact allergy to Myroxylon pereirae resin (MP) (balsam of Peru) is reviewed. The topics presented include the uses, the chemical composition, the frequency of sensitization, the relevance of positive reactions, the MP‐containing products causing allergic contact dermatitis, co‐reactivity with other fragrance and non‐fragrance materials, the sensitizers, the usefulness of MP as a “marker” of fragrance allergy, and the effectiveness of, and indications for, “balsam‐restrictive” diets. Sensitization to MP occurs in 4% to 8% of patients routinely tested for suspected contact dermatitis. There are few adequate data on relevance. Topical pharmaceuticals were formerly, but are not today, important sources of sensitization. Cosmetics and foods or drinks are hardly ever products responsible for sensitization to MP. Positive patch test reactions in the large majority probably result from previous sensitization to MP constituents because of their presence in fragrances and fragranced products, MP thereby acting as marker (or “indicator”) of fragrance allergy. However, fragrance mix I is a more sensitive marker, and the added diagnostic value of testing with MP is unknown. The allergenic ingredients of MP include isoeugenol, eugenol and cinnamyl alcohol, but there are other—largely unknown—chemicals that are responsible for contact allergy. Suggestions are given for further research to address questions thus far unanswered and to improve patient care.
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1111/cod.13263
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cod.13263
- OA Status
- bronze
- Cited By
- 60
- References
- 160
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2922175703
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W2922175703Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1111/cod.13263Digital Object Identifier
- Title
-
Myroxylon pereiraeresin (balsam of Peru) – A critical review of the literature and assessment of the significance of positive patch test reactions and the usefulness of restrictive dietsWork title
- Type
-
reviewOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2019Year of publication
- Publication date
-
2019-03-07Full publication date if available
- Authors
-
Anton C. de GrootList of authors in order
- Landing page
-
https://doi.org/10.1111/cod.13263Publisher landing page
- PDF URL
-
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cod.13263Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
bronzeOpen access status per OpenAlex
- OA URL
-
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cod.13263Direct OA link when available
- Concepts
-
Patch test, Patch testing, Medicine, Test (biology), Dermatology, Allergic contact dermatitis, Contact dermatitis, Allergy, Immunology, Biology, EcologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
60Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 10, 2024: 9, 2023: 5, 2022: 8, 2021: 9Per-year citation counts (last 5 years)
- References (count)
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160Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.and | 44, 59, 63, 104, 139, 161, 180, 206 |
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| abstract_inverted_index.but | 95, 183 |
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| abstract_inverted_index.for, | 65 |
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| abstract_inverted_index.care. | 210 |
| abstract_inverted_index.foods | 105 |
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| abstract_inverted_index.there | 184 |
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| abstract_inverted_index.diets. | 67 |
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| abstract_inverted_index.hardly | 109 |
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| abstract_inverted_index.However, | 152 |
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| abstract_inverted_index.allergy, | 58 |
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| corresponding_author_ids | https://openalex.org/A5088175692 |
| countries_distinct_count | 0 |
| institutions_distinct_count | 1 |
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| citation_normalized_percentile.is_in_top_10_percent | True |