United European Gastroenterology Journal • Vol 7 • No 10
Increased fasting small‐bowel water content in untreated coeliac disease and scleroderma as assessed by magnetic resonance imaging
June 2019 • Ching Lam, David S. Sanders, Peter Lanyon, Klara Garsed, Stephen Foley, Susan E. Pritchard, Luca Marciani, Caroline L. Hoad, Carolyn Costigan, Penny …
Background and aims The regular overnight migrating motor complex (MMC) ensures that the normal fasting small‐bowel water content (SBWC) is minimised. We have applied our recently validated non‐invasive magnetic resonance technique to assess SBWC in newly diagnosed coeliac disease (CD), scleroderma (SCD) and irritable bowel syndrome (IBS), conditions possibly associated with small intestinal bacterial overgrowth (SIBO). Methods A total of 20 CD and 15 SCD patients with gastrointestinal symptoms were compared to 20…