Increasing Fluid Viscosity Ensures Consistent Single-Cell Encapsulation Article Swipe
Emile Pranauskaite
,
Valdemaras Milkus
,
Justas Ritmejeris
,
Rapolas Žilionis
,
Linas Mažutis
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1021/acs.analchem.3c05243
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1021/acs.analchem.3c05243
[Image: see text] High-throughput single-cell analysis typically relies on the isolation of cells of interest in separate compartments for subsequent phenotypic or genotypic characterization. Using microfluidics, this is achieved by isolating individual cells in microdroplets or microwells. However, due to cell-to-cell variability in size, shape, and density, the cell capture efficiencies may vary significantly. This variability can negatively impact the measurements and introduce undesirable artifacts when trying to isolate and characterize heterogeneous cell populations. In this study, we show that single-cell isolation biases in microfluidics can be circumvented by increasing the viscosity of fluids in which cells are dispersed. At a viscosity of 40–50 cP (cP), the cell sedimentation is effectively reduced, resulting in a steady cell flow inside the microfluidics chip and consistent encapsulation in water-in-oil droplets over extended periods of time. This approach allows nearly all cells in a sample to be isolated with the same efficiency, irrespective of their type. Our results show that increased fluid viscosity, rather than cell-adjusted density, provides a more reliable approach to mitigate single-cell isolation biases.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1021/acs.analchem.3c05243
- https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.3c05243
- OA Status
- hybrid
- Cited By
- 3
- References
- 14
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4395043127
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4395043127Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1021/acs.analchem.3c05243Digital Object Identifier
- Title
-
Increasing Fluid Viscosity Ensures Consistent Single-Cell EncapsulationWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-04-22Full publication date if available
- Authors
-
Emile Pranauskaite, Valdemaras Milkus, Justas Ritmejeris, Rapolas Žilionis, Linas MažutisList of authors in order
- Landing page
-
https://doi.org/10.1021/acs.analchem.3c05243Publisher landing page
- PDF URL
-
https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.3c05243Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
-
https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.3c05243Direct OA link when available
- Concepts
-
Chemistry, Encapsulation (networking), Viscosity, Biophysics, Chromatography, Thermodynamics, Chemical engineering, Mechanics, Computer network, Biology, Computer science, Physics, EngineeringTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
3Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 3Per-year citation counts (last 5 years)
- References (count)
-
14Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4395043127 |
|---|---|
| doi | https://doi.org/10.1021/acs.analchem.3c05243 |
| ids.doi | https://doi.org/10.1021/acs.analchem.3c05243 |
| ids.openalex | https://openalex.org/W4395043127 |
| fwci | 1.10257789 |
| type | article |
| title | Increasing Fluid Viscosity Ensures Consistent Single-Cell Encapsulation |
| awards[0].id | https://openalex.org/G6392967362 |
| awards[0].funder_id | https://openalex.org/F4320322689 |
| awards[0].display_name | |
| awards[0].funder_award_id | 01.2.2-LMT-K-718-04-0002 |
| awards[0].funder_display_name | Lietuvos Mokslo Taryba |
| biblio.issue | 18 |
| biblio.volume | 96 |
| biblio.last_page | 6905 |
| biblio.first_page | 6898 |
| topics[0].id | https://openalex.org/T11407 |
| topics[0].field.id | https://openalex.org/fields/22 |
| topics[0].field.display_name | Engineering |
| topics[0].score | 0.9995999932289124 |
| topics[0].domain.id | https://openalex.org/domains/3 |
| topics[0].domain.display_name | Physical Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2204 |
| topics[0].subfield.display_name | Biomedical Engineering |
| topics[0].display_name | Innovative Microfluidic and Catalytic Techniques Innovation |
| topics[1].id | https://openalex.org/T10839 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9969000220298767 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2746 |
| topics[1].subfield.display_name | Surgery |
| topics[1].display_name | Pancreatic function and diabetes |
| topics[2].id | https://openalex.org/T11190 |
| topics[2].field.id | https://openalex.org/fields/22 |
| topics[2].field.display_name | Engineering |
| topics[2].score | 0.996399998664856 |
| topics[2].domain.id | https://openalex.org/domains/3 |
| topics[2].domain.display_name | Physical Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2204 |
| topics[2].subfield.display_name | Biomedical Engineering |
| topics[2].display_name | 3D Printing in Biomedical Research |
| funders[0].id | https://openalex.org/F4320322689 |
| funders[0].ror | https://ror.org/02gs16m83 |
| funders[0].display_name | Lietuvos Mokslo Taryba |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C185592680 |
| concepts[0].level | 0 |
| concepts[0].score | 0.9725130796432495 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q2329 |
| concepts[0].display_name | Chemistry |
| concepts[1].id | https://openalex.org/C81147070 |
| concepts[1].level | 2 |
| concepts[1].score | 0.6156063675880432 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q1172449 |
| concepts[1].display_name | Encapsulation (networking) |
| concepts[2].id | https://openalex.org/C127172972 |
| concepts[2].level | 2 |
| concepts[2].score | 0.4629780650138855 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q128709 |
| concepts[2].display_name | Viscosity |
| concepts[3].id | https://openalex.org/C12554922 |
| concepts[3].level | 1 |
| concepts[3].score | 0.4164274334907532 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q7100 |
| concepts[3].display_name | Biophysics |
| concepts[4].id | https://openalex.org/C43617362 |
| concepts[4].level | 1 |
| concepts[4].score | 0.38422417640686035 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q170050 |
| concepts[4].display_name | Chromatography |
| concepts[5].id | https://openalex.org/C97355855 |
| concepts[5].level | 1 |
| concepts[5].score | 0.34568941593170166 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q11473 |
| concepts[5].display_name | Thermodynamics |
| concepts[6].id | https://openalex.org/C42360764 |
| concepts[6].level | 1 |
| concepts[6].score | 0.3440542221069336 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q83588 |
| concepts[6].display_name | Chemical engineering |
| concepts[7].id | https://openalex.org/C57879066 |
| concepts[7].level | 1 |
| concepts[7].score | 0.3384942412376404 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q41217 |
| concepts[7].display_name | Mechanics |
| concepts[8].id | https://openalex.org/C31258907 |
| concepts[8].level | 1 |
| concepts[8].score | 0.0 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q1301371 |
| concepts[8].display_name | Computer network |
| concepts[9].id | https://openalex.org/C86803240 |
| concepts[9].level | 0 |
| concepts[9].score | 0.0 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[9].display_name | Biology |
| concepts[10].id | https://openalex.org/C41008148 |
| concepts[10].level | 0 |
| concepts[10].score | 0.0 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q21198 |
| concepts[10].display_name | Computer science |
| concepts[11].id | https://openalex.org/C121332964 |
| concepts[11].level | 0 |
| concepts[11].score | 0.0 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q413 |
| concepts[11].display_name | Physics |
| concepts[12].id | https://openalex.org/C127413603 |
| concepts[12].level | 0 |
| concepts[12].score | 0.0 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q11023 |
| concepts[12].display_name | Engineering |
| keywords[0].id | https://openalex.org/keywords/chemistry |
| keywords[0].score | 0.9725130796432495 |
| keywords[0].display_name | Chemistry |
| keywords[1].id | https://openalex.org/keywords/encapsulation |
| keywords[1].score | 0.6156063675880432 |
| keywords[1].display_name | Encapsulation (networking) |
| keywords[2].id | https://openalex.org/keywords/viscosity |
| keywords[2].score | 0.4629780650138855 |
| keywords[2].display_name | Viscosity |
| keywords[3].id | https://openalex.org/keywords/biophysics |
| keywords[3].score | 0.4164274334907532 |
| keywords[3].display_name | Biophysics |
| keywords[4].id | https://openalex.org/keywords/chromatography |
| keywords[4].score | 0.38422417640686035 |
| keywords[4].display_name | Chromatography |
| keywords[5].id | https://openalex.org/keywords/thermodynamics |
| keywords[5].score | 0.34568941593170166 |
| keywords[5].display_name | Thermodynamics |
| keywords[6].id | https://openalex.org/keywords/chemical-engineering |
| keywords[6].score | 0.3440542221069336 |
| keywords[6].display_name | Chemical engineering |
| keywords[7].id | https://openalex.org/keywords/mechanics |
| keywords[7].score | 0.3384942412376404 |
| keywords[7].display_name | Mechanics |
| language | en |
| locations[0].id | doi:10.1021/acs.analchem.3c05243 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S191963794 |
| locations[0].source.issn | 0003-2700, 1520-6882 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 0003-2700 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Analytical Chemistry |
| locations[0].source.host_organization | https://openalex.org/P4310320006 |
| locations[0].source.host_organization_name | American Chemical Society |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320006 |
| locations[0].source.host_organization_lineage_names | American Chemical Society |
| locations[0].license | cc-by |
| locations[0].pdf_url | https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.3c05243 |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Analytical Chemistry |
| locations[0].landing_page_url | https://doi.org/10.1021/acs.analchem.3c05243 |
| locations[1].id | pmh:oai:pubmedcentral.nih.gov:11079858 |
| locations[1].is_oa | True |
| locations[1].source.id | https://openalex.org/S2764455111 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed Central |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | cc-by |
| locations[1].pdf_url | |
| locations[1].version | submittedVersion |
| locations[1].raw_type | Text |
| locations[1].license_id | https://openalex.org/licenses/cc-by |
| locations[1].is_accepted | False |
| locations[1].is_published | False |
| locations[1].raw_source_name | Anal Chem |
| locations[1].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/11079858 |
| indexed_in | crossref |
| authorships[0].author.id | https://openalex.org/A5095845106 |
| authorships[0].author.orcid | |
| authorships[0].author.display_name | Emile Pranauskaite |
| authorships[0].countries | LT |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I173212132 |
| authorships[0].affiliations[0].raw_affiliation_string | Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius LT 10257, Lithuania |
| authorships[0].institutions[0].id | https://openalex.org/I173212132 |
| authorships[0].institutions[0].ror | https://ror.org/03nadee84 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I173212132 |
| authorships[0].institutions[0].country_code | LT |
| authorships[0].institutions[0].display_name | Vilnius University |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Emile Pranauskaite |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius LT 10257, Lithuania |
| authorships[1].author.id | https://openalex.org/A5066293131 |
| authorships[1].author.orcid | |
| authorships[1].author.display_name | Valdemaras Milkus |
| authorships[1].countries | LT |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I173212132 |
| authorships[1].affiliations[0].raw_affiliation_string | Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius LT 10257, Lithuania |
| authorships[1].institutions[0].id | https://openalex.org/I173212132 |
| authorships[1].institutions[0].ror | https://ror.org/03nadee84 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I173212132 |
| authorships[1].institutions[0].country_code | LT |
| authorships[1].institutions[0].display_name | Vilnius University |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Valdemaras Milkus |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius LT 10257, Lithuania |
| authorships[2].author.id | https://openalex.org/A5017422545 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-6166-4594 |
| authorships[2].author.display_name | Justas Ritmejeris |
| authorships[2].countries | LT |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I173212132 |
| authorships[2].affiliations[0].raw_affiliation_string | Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius LT 10257, Lithuania |
| authorships[2].institutions[0].id | https://openalex.org/I173212132 |
| authorships[2].institutions[0].ror | https://ror.org/03nadee84 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I173212132 |
| authorships[2].institutions[0].country_code | LT |
| authorships[2].institutions[0].display_name | Vilnius University |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Justas Ritmejeris |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius LT 10257, Lithuania |
| authorships[3].author.id | https://openalex.org/A5048181858 |
| authorships[3].author.orcid | https://orcid.org/0000-0002-9697-2431 |
| authorships[3].author.display_name | Rapolas Žilionis |
| authorships[3].countries | LT |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I173212132 |
| authorships[3].affiliations[0].raw_affiliation_string | Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius LT 10257, Lithuania |
| authorships[3].institutions[0].id | https://openalex.org/I173212132 |
| authorships[3].institutions[0].ror | https://ror.org/03nadee84 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I173212132 |
| authorships[3].institutions[0].country_code | LT |
| authorships[3].institutions[0].display_name | Vilnius University |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Rapolas Zilionis |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius LT 10257, Lithuania |
| authorships[4].author.id | https://openalex.org/A5069697645 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-5552-6427 |
| authorships[4].author.display_name | Linas Mažutis |
| authorships[4].countries | LT |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I173212132 |
| authorships[4].affiliations[0].raw_affiliation_string | Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius LT 10257, Lithuania |
| authorships[4].institutions[0].id | https://openalex.org/I173212132 |
| authorships[4].institutions[0].ror | https://ror.org/03nadee84 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I173212132 |
| authorships[4].institutions[0].country_code | LT |
| authorships[4].institutions[0].display_name | Vilnius University |
| authorships[4].author_position | last |
| authorships[4].raw_author_name | Linas Mazutis |
| authorships[4].is_corresponding | True |
| authorships[4].raw_affiliation_strings | Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius LT 10257, Lithuania |
| has_content.pdf | True |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.3c05243 |
| open_access.oa_status | hybrid |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Increasing Fluid Viscosity Ensures Consistent Single-Cell Encapsulation |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T11407 |
| primary_topic.field.id | https://openalex.org/fields/22 |
| primary_topic.field.display_name | Engineering |
| primary_topic.score | 0.9995999932289124 |
| primary_topic.domain.id | https://openalex.org/domains/3 |
| primary_topic.domain.display_name | Physical Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2204 |
| primary_topic.subfield.display_name | Biomedical Engineering |
| primary_topic.display_name | Innovative Microfluidic and Catalytic Techniques Innovation |
| related_works | https://openalex.org/W2277514059, https://openalex.org/W1548373682, https://openalex.org/W2233266406, https://openalex.org/W4210441588, https://openalex.org/W2913147969, https://openalex.org/W2031154819, https://openalex.org/W4395456051, https://openalex.org/W2521976574, https://openalex.org/W2377586764, https://openalex.org/W4399422826 |
| cited_by_count | 3 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 3 |
| locations_count | 2 |
| best_oa_location.id | doi:10.1021/acs.analchem.3c05243 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S191963794 |
| best_oa_location.source.issn | 0003-2700, 1520-6882 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | 0003-2700 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | Analytical Chemistry |
| best_oa_location.source.host_organization | https://openalex.org/P4310320006 |
| best_oa_location.source.host_organization_name | American Chemical Society |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310320006 |
| best_oa_location.source.host_organization_lineage_names | American Chemical Society |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.3c05243 |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Analytical Chemistry |
| best_oa_location.landing_page_url | https://doi.org/10.1021/acs.analchem.3c05243 |
| primary_location.id | doi:10.1021/acs.analchem.3c05243 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S191963794 |
| primary_location.source.issn | 0003-2700, 1520-6882 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 0003-2700 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Analytical Chemistry |
| primary_location.source.host_organization | https://openalex.org/P4310320006 |
| primary_location.source.host_organization_name | American Chemical Society |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320006 |
| primary_location.source.host_organization_lineage_names | American Chemical Society |
| primary_location.license | cc-by |
| primary_location.pdf_url | https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.3c05243 |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Analytical Chemistry |
| primary_location.landing_page_url | https://doi.org/10.1021/acs.analchem.3c05243 |
| publication_date | 2024-04-22 |
| publication_year | 2024 |
| referenced_works | https://openalex.org/W1980221373, https://openalex.org/W2135937351, https://openalex.org/W2951506174, https://openalex.org/W2102212449, https://openalex.org/W4322768301, https://openalex.org/W2015554529, https://openalex.org/W2305250634, https://openalex.org/W2975634117, https://openalex.org/W2086027952, https://openalex.org/W3041482856, https://openalex.org/W1999621719, https://openalex.org/W4221007502, https://openalex.org/W658742552, https://openalex.org/W1558905924 |
| referenced_works_count | 14 |
| abstract_inverted_index.a | 100, 114, 140, 165 |
| abstract_inverted_index.At | 99 |
| abstract_inverted_index.In | 74 |
| abstract_inverted_index.be | 86, 143 |
| abstract_inverted_index.by | 29, 88 |
| abstract_inverted_index.cP | 104 |
| abstract_inverted_index.in | 15, 33, 42, 83, 94, 113, 125, 139 |
| abstract_inverted_index.is | 27, 109 |
| abstract_inverted_index.of | 11, 13, 92, 102, 131, 150 |
| abstract_inverted_index.on | 8 |
| abstract_inverted_index.or | 21, 35 |
| abstract_inverted_index.to | 39, 67, 142, 169 |
| abstract_inverted_index.we | 77 |
| abstract_inverted_index.Our | 153 |
| abstract_inverted_index.all | 137 |
| abstract_inverted_index.and | 45, 61, 69, 122 |
| abstract_inverted_index.are | 97 |
| abstract_inverted_index.can | 56, 85 |
| abstract_inverted_index.due | 38 |
| abstract_inverted_index.for | 18 |
| abstract_inverted_index.may | 51 |
| abstract_inverted_index.see | 1 |
| abstract_inverted_index.the | 9, 47, 59, 90, 106, 119, 146 |
| abstract_inverted_index.This | 54, 133 |
| abstract_inverted_index.cell | 48, 72, 107, 116 |
| abstract_inverted_index.chip | 121 |
| abstract_inverted_index.flow | 117 |
| abstract_inverted_index.more | 166 |
| abstract_inverted_index.over | 128 |
| abstract_inverted_index.same | 147 |
| abstract_inverted_index.show | 78, 155 |
| abstract_inverted_index.than | 161 |
| abstract_inverted_index.that | 79, 156 |
| abstract_inverted_index.this | 26, 75 |
| abstract_inverted_index.vary | 52 |
| abstract_inverted_index.when | 65 |
| abstract_inverted_index.with | 145 |
| abstract_inverted_index.(cP), | 105 |
| abstract_inverted_index.Using | 24 |
| abstract_inverted_index.cells | 12, 32, 96, 138 |
| abstract_inverted_index.fluid | 158 |
| abstract_inverted_index.size, | 43 |
| abstract_inverted_index.text] | 2 |
| abstract_inverted_index.their | 151 |
| abstract_inverted_index.time. | 132 |
| abstract_inverted_index.type. | 152 |
| abstract_inverted_index.which | 95 |
| abstract_inverted_index.allows | 135 |
| abstract_inverted_index.biases | 82 |
| abstract_inverted_index.fluids | 93 |
| abstract_inverted_index.impact | 58 |
| abstract_inverted_index.inside | 118 |
| abstract_inverted_index.nearly | 136 |
| abstract_inverted_index.rather | 160 |
| abstract_inverted_index.relies | 7 |
| abstract_inverted_index.sample | 141 |
| abstract_inverted_index.shape, | 44 |
| abstract_inverted_index.steady | 115 |
| abstract_inverted_index.study, | 76 |
| abstract_inverted_index.trying | 66 |
| abstract_inverted_index.40–50 | 103 |
| abstract_inverted_index.[Image: | 0 |
| abstract_inverted_index.biases. | 173 |
| abstract_inverted_index.capture | 49 |
| abstract_inverted_index.isolate | 68 |
| abstract_inverted_index.periods | 130 |
| abstract_inverted_index.results | 154 |
| abstract_inverted_index.However, | 37 |
| abstract_inverted_index.achieved | 28 |
| abstract_inverted_index.analysis | 5 |
| abstract_inverted_index.approach | 134, 168 |
| abstract_inverted_index.density, | 46, 163 |
| abstract_inverted_index.droplets | 127 |
| abstract_inverted_index.extended | 129 |
| abstract_inverted_index.interest | 14 |
| abstract_inverted_index.isolated | 144 |
| abstract_inverted_index.mitigate | 170 |
| abstract_inverted_index.provides | 164 |
| abstract_inverted_index.reduced, | 111 |
| abstract_inverted_index.reliable | 167 |
| abstract_inverted_index.separate | 16 |
| abstract_inverted_index.artifacts | 64 |
| abstract_inverted_index.genotypic | 22 |
| abstract_inverted_index.increased | 157 |
| abstract_inverted_index.introduce | 62 |
| abstract_inverted_index.isolating | 30 |
| abstract_inverted_index.isolation | 10, 81, 172 |
| abstract_inverted_index.resulting | 112 |
| abstract_inverted_index.typically | 6 |
| abstract_inverted_index.viscosity | 91, 101 |
| abstract_inverted_index.consistent | 123 |
| abstract_inverted_index.dispersed. | 98 |
| abstract_inverted_index.increasing | 89 |
| abstract_inverted_index.individual | 31 |
| abstract_inverted_index.negatively | 57 |
| abstract_inverted_index.phenotypic | 20 |
| abstract_inverted_index.subsequent | 19 |
| abstract_inverted_index.viscosity, | 159 |
| abstract_inverted_index.effectively | 110 |
| abstract_inverted_index.efficiency, | 148 |
| abstract_inverted_index.microwells. | 36 |
| abstract_inverted_index.single-cell | 4, 80, 171 |
| abstract_inverted_index.undesirable | 63 |
| abstract_inverted_index.variability | 41, 55 |
| abstract_inverted_index.cell-to-cell | 40 |
| abstract_inverted_index.characterize | 70 |
| abstract_inverted_index.circumvented | 87 |
| abstract_inverted_index.compartments | 17 |
| abstract_inverted_index.efficiencies | 50 |
| abstract_inverted_index.irrespective | 149 |
| abstract_inverted_index.measurements | 60 |
| abstract_inverted_index.populations. | 73 |
| abstract_inverted_index.water-in-oil | 126 |
| abstract_inverted_index.cell-adjusted | 162 |
| abstract_inverted_index.encapsulation | 124 |
| abstract_inverted_index.heterogeneous | 71 |
| abstract_inverted_index.microdroplets | 34 |
| abstract_inverted_index.microfluidics | 84, 120 |
| abstract_inverted_index.sedimentation | 108 |
| abstract_inverted_index.microfluidics, | 25 |
| abstract_inverted_index.significantly. | 53 |
| abstract_inverted_index.High-throughput | 3 |
| abstract_inverted_index.characterization. | 23 |
| cited_by_percentile_year.max | 97 |
| cited_by_percentile_year.min | 96 |
| corresponding_author_ids | https://openalex.org/A5069697645 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 5 |
| corresponding_institution_ids | https://openalex.org/I173212132 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/7 |
| sustainable_development_goals[0].score | 0.5099999904632568 |
| sustainable_development_goals[0].display_name | Affordable and clean energy |
| citation_normalized_percentile.value | 0.67120337 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |