Initial gonadotropin levels and sperm parameters differentiate the response to clomiphene citrate in subfertile men Article Swipe

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Tommy Jiang , Vadim Osadchiy , Alvaro Santamaria , Michael Zheng , Neilufar Modiri , John T. Sigalos , Keith V. Regets , Jesse N. Mills , Sriram V. Eleswarapu ·

YOU? · · 2022 · Open Access · · DOI: https://doi.org/10.21037/tau-21-987

Men with lower gonadotropin levels may expect greater degree of improvement in both hormone and semen parameters with use of CC. Men with azoospermia do not benefit based on semen analyses alone. Degree of non-azoospermia does not affect magnitude of improvement. CC had decreasing efficacy at higher initial gonadotropin levels. These data may provide guidance in stratifying and counseling men for CC treatment.

Related Topics

Semen

Medicine

Follicle-Stimulating Hormone

Concepts

Semen analysis Semen Medicine Sperm Clomifene Gonadotropin Confidence interval Univariate analysis Odds ratio Multivariate analysis Follicle-stimulating hormone Infertility Gynecology Pregnancy Internal medicine Hormone Urology Andrology Biology Ovulation Ovulation induction Luteinizing hormone Genetics

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Type: article
Language: en
Landing Page: https://doi.org/10.21037/tau-21-987
PDF: https://tau.amegroups.com/article/viewFile/89583/pdf
OA Status: diamond
Cited By: 4
References: 30
Related Works: 10
OpenAlex ID: https://openalex.org/W4212866839

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OpenAlex ID: https://openalex.org/W4212866839

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DOI: https://doi.org/10.21037/tau-21-987

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Title: Initial gonadotropin levels and sperm parameters differentiate the response to clomiphene citrate in subfertile men

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Type: article

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Language: en

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Publication year: 2022

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Publication date: 2022-02-01

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Authors: Tommy Jiang, Vadim Osadchiy, Alvaro Santamaria, Michael Zheng, Neilufar Modiri, John T. Sigalos, Keith V. Regets, Jesse N. Mills, Sriram V. Eleswarapu

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Landing page: https://doi.org/10.21037/tau-21-987

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PDF URL: https://tau.amegroups.com/article/viewFile/89583/pdf

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Concepts: Semen analysis, Semen, Medicine, Sperm, Clomifene, Gonadotropin, Confidence interval, Univariate analysis, Odds ratio, Multivariate analysis, Follicle-stimulating hormone, Infertility, Gynecology, Pregnancy, Internal medicine, Hormone, Urology, Andrology, Biology, Ovulation, Ovulation induction, Luteinizing hormone, Genetics

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Cited by: 4

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Citations by year (recent): 2025: 2, 2024: 1, 2022: 1

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Related works (count): 10

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