Integration of Mass Cytometry and Mass Spectrometry Imaging for Spatially Resolved Single Cell Metabolic Profiling Article Swipe
Joana B. Nunes
,
Marieke E. Ijsselsteijn
,
Tamim Abdelaal
,
Rick Ursem
,
Manon van der Ploeg
,
Bart Everts
,
Ahmed Mahfouz
,
Bram Heijs
,
Noel F.C.C. de Miranda
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1101/2023.08.29.555282
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1101/2023.08.29.555282
Integration of spatial omics technologies can provide important insights into the biology of tissues. We combined mass spectrometry imaging-based metabolomics and imaging mass cytometry-based immunophenotyping on the same single tissue section to reveal metabolic heterogeneity within tissues and its association with specific cell populations like cancer cells or immune cells. This approach has the potential to greatly increase our understanding of tissue-level interplay between metabolic processes and their cellular components.
Related Topics
Concepts
Mass cytometry
Mass spectrometry imaging
Metabolomics
Immunophenotyping
Computational biology
Mass spectrometry
Flow cytometry
Cytometry
Biology
Systems biology
Profiling (computer programming)
Cell
Chemistry
Bioinformatics
Computer science
Biochemistry
Molecular biology
Phenotype
Chromatography
Operating system
Gene
Metadata
- Type
- preprint
- Language
- en
- Landing Page
- https://doi.org/10.1101/2023.08.29.555282
- https://www.biorxiv.org/content/biorxiv/early/2023/08/30/2023.08.29.555282.full.pdf
- OA Status
- green
- Cited By
- 3
- References
- 17
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4386269702
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4386269702Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1101/2023.08.29.555282Digital Object Identifier
- Title
-
Integration of Mass Cytometry and Mass Spectrometry Imaging for Spatially Resolved Single Cell Metabolic ProfilingWork title
- Type
-
preprintOpenAlex work type
- Language
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enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-08-30Full publication date if available
- Authors
-
Joana B. Nunes, Marieke E. Ijsselsteijn, Tamim Abdelaal, Rick Ursem, Manon van der Ploeg, Bart Everts, Ahmed Mahfouz, Bram Heijs, Noel F.C.C. de MirandaList of authors in order
- Landing page
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https://doi.org/10.1101/2023.08.29.555282Publisher landing page
- PDF URL
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https://www.biorxiv.org/content/biorxiv/early/2023/08/30/2023.08.29.555282.full.pdfDirect link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- OA URL
-
https://www.biorxiv.org/content/biorxiv/early/2023/08/30/2023.08.29.555282.full.pdfDirect OA link when available
- Concepts
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Mass cytometry, Mass spectrometry imaging, Metabolomics, Immunophenotyping, Computational biology, Mass spectrometry, Flow cytometry, Cytometry, Biology, Systems biology, Profiling (computer programming), Cell, Chemistry, Bioinformatics, Computer science, Biochemistry, Molecular biology, Phenotype, Chromatography, Operating system, GeneTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
3Total citation count in OpenAlex
- Citations by year (recent)
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2025: 1, 2024: 2Per-year citation counts (last 5 years)
- References (count)
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17Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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