Intended Bridging Therapy or Intravenous Thrombolysis Alone in Minor Stroke With Basilar Artery Occlusion Article Swipe
Pierre Seners
,
Cyril Dargazanli
,
Michel Piotin
,
Denis Sablot
,
Serge Bracard
,
Philippe Niclot
,
Jean‐Claude Baron
,
Guillaume Turc
,
Claire Perrin
,
Caroline Arquizan
,
Chantal Lamy
,
Igor Sibon
,
Michaël Obadia
,
Jérémie Papassin
,
Hilde Hénon
,
Cécile Preterre
,
Laurent Suissa
,
Séverine Debiais
,
Aïcha Lyoubi
,
Pierre Garnier
,
I. Girard-Buttaz
,
Bertrand Lapergue
,
Aude Triquenot
,
Duc-Long Duong
,
Nadia Laksiri
,
Gioia Mione
,
Jean‐Louis Mas
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1161/strokeaha.120.030992
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1161/strokeaha.120.030992
Background and Purpose: Whether bridging therapy (intravenous thrombolysis [IVT] followed by mechanical thrombectomy) is superior to IVT alone in minor stroke with basilar artery occlusion remains uncertain. Methods: Multicentric retrospective observational study of consecutive minor stroke patients (National Institutes of Health Stroke Scale score ≤5) with basilar artery occlusion intended for IVT alone or bridging therapy. Propensity-score weighting was used to reduce baseline between-groups differences, and residual imbalance was addressed through adjusted logistic regression, with excellent outcome (3-month modified Rankin Scale score 0–1) as the dependent variable. Results: Fifty-seven patients were included (28 and 29 in the bridging therapy and IVT alone groups, respectively). Following propensity-score weighting, the distribution of baseline clinical and radiological variables was similar across the 2 patient groups, except age, posterior circulation Alberta Stroke Program Early CT Score, history of hypertension and smoking, and onset-to-IVT time. Compared with IVT alone, bridging therapy was associated with excellent outcome (adjusted odds ratio=3.37 [95% CI, 1.13–10.03]; P =0.03). No patient experienced symptomatic intracranial hemorrhage. Conclusions: Our results suggest that bridging therapy may be superior to IVT alone in minor stroke with basilar artery occlusion.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1161/strokeaha.120.030992
- https://www.ahajournals.org/doi/pdf/10.1161/STROKEAHA.120.030992
- OA Status
- bronze
- Cited By
- 31
- References
- 7
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3118872896
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3118872896Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1161/strokeaha.120.030992Digital Object Identifier
- Title
-
Intended Bridging Therapy or Intravenous Thrombolysis Alone in Minor Stroke With Basilar Artery OcclusionWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2021Year of publication
- Publication date
-
2021-01-07Full publication date if available
- Authors
-
Pierre Seners, Cyril Dargazanli, Michel Piotin, Denis Sablot, Serge Bracard, Philippe Niclot, Jean‐Claude Baron, Guillaume Turc, Claire Perrin, Caroline Arquizan, Chantal Lamy, Igor Sibon, Michaël Obadia, Jérémie Papassin, Hilde Hénon, Cécile Preterre, Laurent Suissa, Séverine Debiais, Aïcha Lyoubi, Pierre Garnier, I. Girard-Buttaz, Bertrand Lapergue, Aude Triquenot, Duc-Long Duong, Nadia Laksiri, Gioia Mione, Jean‐Louis MasList of authors in order
- Landing page
-
https://doi.org/10.1161/strokeaha.120.030992Publisher landing page
- PDF URL
-
https://www.ahajournals.org/doi/pdf/10.1161/STROKEAHA.120.030992Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
bronzeOpen access status per OpenAlex
- OA URL
-
https://www.ahajournals.org/doi/pdf/10.1161/STROKEAHA.120.030992Direct OA link when available
- Concepts
-
Medicine, Thrombolysis, Modified Rankin Scale, Basilar artery, Stroke (engine), Odds ratio, Propensity score matching, Internal medicine, Retrospective cohort study, Surgery, Cardiology, Ischemic stroke, Ischemia, Engineering, Mechanical engineering, Myocardial infarctionTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
31Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 10, 2024: 8, 2023: 4, 2022: 7, 2021: 2Per-year citation counts (last 5 years)
- References (count)
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7Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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