Exploring foci of:
Frontiers in Pharmacology • Vol 11
Interplay Between Ion Channels and the Wnt/β-Catenin Signaling Pathway in Cancers
September 2020 • Raphael Rapetti‐Mauss, Camille Berenguier, Benoit Allegrini, Olivier Soriani
Increasing evidence point out the important roles of ion channels in the physiopathology of cancers, so that these proteins are now considered as potential new therapeutic targets and biomarkers in this disease. Indeed, ion channels have been largely described to participate in many hallmarks of cancers such as migration, invasion, proliferation, angiogenesis, and resistance to apoptosis. At the molecular level, the development of cancers is characterised by alterations in transduction pathways that control cell b…
Ion Channel
Cancer
Angiogenesis
Catenin Beta-1
Biology
Bioinformatics
Cell Biology
Neuroscience