Intrarenal pressure with hand-pump or pressurized-bag irrigation: randomized clinical trial at retrograde intrarenal surgery Article Swipe
Stefanie Croghan
,
Sorcha O’Meara
,
Eoghan M. Cunnane
,
Helen Purtill
,
Michael T. Walsh
,
Fergal J. O’Brien
,
Rustom P. Manecksha
,
Barry B. McGuire
,
Kieran J. Breen
,
Niall F. Davis
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1093/bjs/znae137
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1093/bjs/znae137
Background The aim was to ascertain the impact of irrigation technique on human intrarenal pressure during retrograde intrarenal surgery. Methods A parallel randomized trial recruited patients across three hospital sites. Patients undergoing retrograde intrarenal surgery for renal stone treatment with an 11/13-Fr ureteral access sheath were allocated randomly to 100 mmHg pressurized-bag (PB) or manual hand-pump (HP) irrigation. The primary outcome was mean procedural intrarenal pressure. Secondary outcomes included maximum intrarenal pressure, variance, visualization, HP force of usage, procedure duration, stone clearance, and clinical outcomes. Live intrarenal pressure monitoring was performed using a COMETTMII pressure guidewire, deployed cystoscopically to the renal pelvis. The operating team was blinded to the intrarenal pressure. Results Thirty-eight patients were randomized between July and November 2023 (trial closure). The final analysis included 34 patients (PB 16; HP 18). Compared with PB irrigation, HP irrigation resulted in significantly higher mean intrarenal pressure (mean(s.d.) 62.29(27.45) versus 38.16(16.84) mmHg; 95% c.i. for difference in means (MD) 7.97 to 40.29 mmHg; P = 0.005) and maximum intrarenal pressure (192.71(106.23) versus 68.04(24.16) mmHg; 95% c.i. for MD 70.76 to 178.59 mmHg; P < 0.001), along with greater variance in intrarenal pressure (log transformed) (6.23(1.59) versus 4.60(1.30); 95% c.i. for MD 0.62 to 2.66; P = 0.001). Surgeon satisfaction with procedural vision reported on a scale of 10 was higher with PB compared with HP irrigation (mean(s.d.) 8.75(0.58) versus 6.28(1.27); 95% c.i. for MD 1.79 to 3.16; P < 0.001). Subjective HP usage force did not correlate significantly with transmitted intrarenal pressure (Pearson R = −0.15, P = 0.57). One patient (HP arm) developed urosepsis. Conclusion Manual HP irrigation resulted in higher and more fluctuant intrarenal pressure trace (with inferior visual clarity) than 100-mmHg PB irrigation. Registration number osf.io/jmg2h (https://osf.io/).
Related Topics
Concepts
Medicine
Randomized controlled trial
Mean arterial pressure
Blood pressure
Surgery
Urology
Internal medicine
Heart rate
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/bjs/znae137
- https://academic.oup.com/bjs/article-pdf/111/6/znae137/58238807/znae137.pdf
- OA Status
- hybrid
- Cited By
- 12
- References
- 16
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4399718295
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4399718295Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1093/bjs/znae137Digital Object Identifier
- Title
-
Intrarenal pressure with hand-pump or pressurized-bag irrigation: randomized clinical trial at retrograde intrarenal surgeryWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-06-01Full publication date if available
- Authors
-
Stefanie Croghan, Sorcha O’Meara, Eoghan M. Cunnane, Helen Purtill, Michael T. Walsh, Fergal J. O’Brien, Rustom P. Manecksha, Barry B. McGuire, Kieran J. Breen, Niall F. DavisList of authors in order
- Landing page
-
https://doi.org/10.1093/bjs/znae137Publisher landing page
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https://academic.oup.com/bjs/article-pdf/111/6/znae137/58238807/znae137.pdfDirect link to full text PDF
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YesWhether a free full text is available
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hybridOpen access status per OpenAlex
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https://academic.oup.com/bjs/article-pdf/111/6/znae137/58238807/znae137.pdfDirect OA link when available
- Concepts
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Medicine, Randomized controlled trial, Mean arterial pressure, Blood pressure, Surgery, Urology, Internal medicine, Heart rateTop concepts (fields/topics) attached by OpenAlex
- Cited by
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12Total citation count in OpenAlex
- Citations by year (recent)
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2025: 12Per-year citation counts (last 5 years)
- References (count)
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16Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.Live | 86 |
| abstract_inverted_index.arm) | 262 |
| abstract_inverted_index.c.i. | 153, 175, 198, 231 |
| abstract_inverted_index.mean | 63, 144 |
| abstract_inverted_index.mmHg | 51 |
| abstract_inverted_index.more | 273 |
| abstract_inverted_index.team | 105 |
| abstract_inverted_index.than | 282 |
| abstract_inverted_index.were | 46, 115 |
| abstract_inverted_index.with | 40, 135, 186, 209, 220, 223, 248 |
| abstract_inverted_index.(with | 278 |
| abstract_inverted_index.2.66; | 203 |
| abstract_inverted_index.3.16; | 236 |
| abstract_inverted_index.40.29 | 161 |
| abstract_inverted_index.70.76 | 178 |
| abstract_inverted_index.along | 185 |
| abstract_inverted_index.final | 125 |
| abstract_inverted_index.force | 76, 243 |
| abstract_inverted_index.human | 13 |
| abstract_inverted_index.means | 157 |
| abstract_inverted_index.mmHg; | 151, 162, 173, 181 |
| abstract_inverted_index.renal | 37, 101 |
| abstract_inverted_index.scale | 215 |
| abstract_inverted_index.stone | 38, 81 |
| abstract_inverted_index.three | 28 |
| abstract_inverted_index.trace | 277 |
| abstract_inverted_index.trial | 24 |
| abstract_inverted_index.usage | 242 |
| abstract_inverted_index.using | 92 |
| abstract_inverted_index.(trial | 122 |
| abstract_inverted_index.0.005) | 165 |
| abstract_inverted_index.0.57). | 258 |
| abstract_inverted_index.178.59 | 180 |
| abstract_inverted_index.Manual | 266 |
| abstract_inverted_index.access | 44 |
| abstract_inverted_index.across | 27 |
| abstract_inverted_index.during | 16 |
| abstract_inverted_index.higher | 143, 219, 271 |
| abstract_inverted_index.impact | 8 |
| abstract_inverted_index.manual | 55 |
| abstract_inverted_index.number | 287 |
| abstract_inverted_index.sheath | 45 |
| abstract_inverted_index.sites. | 30 |
| abstract_inverted_index.usage, | 78 |
| abstract_inverted_index.versus | 149, 171, 195, 228 |
| abstract_inverted_index.vision | 211 |
| abstract_inverted_index.visual | 280 |
| abstract_inverted_index.0.001), | 184 |
| abstract_inverted_index.0.001). | 206, 239 |
| abstract_inverted_index.Methods | 20 |
| abstract_inverted_index.Results | 112 |
| abstract_inverted_index.Surgeon | 207 |
| abstract_inverted_index.between | 117 |
| abstract_inverted_index.blinded | 107 |
| abstract_inverted_index.greater | 187 |
| abstract_inverted_index.maximum | 70, 167 |
| abstract_inverted_index.outcome | 61 |
| abstract_inverted_index.patient | 260 |
| abstract_inverted_index.pelvis. | 102 |
| abstract_inverted_index.primary | 60 |
| abstract_inverted_index.surgery | 35 |
| abstract_inverted_index.&lt; | 183, 238 |
| abstract_inverted_index.(Pearson | 252 |
| abstract_inverted_index.100-mmHg | 283 |
| abstract_inverted_index.11/13-Fr | 42 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.Compared | 134 |
| abstract_inverted_index.November | 120 |
| abstract_inverted_index.Patients | 31 |
| abstract_inverted_index.analysis | 126 |
| abstract_inverted_index.clarity) | 281 |
| abstract_inverted_index.clinical | 84 |
| abstract_inverted_index.compared | 222 |
| abstract_inverted_index.deployed | 97 |
| abstract_inverted_index.hospital | 29 |
| abstract_inverted_index.included | 69, 127 |
| abstract_inverted_index.inferior | 279 |
| abstract_inverted_index.outcomes | 68 |
| abstract_inverted_index.parallel | 22 |
| abstract_inverted_index.patients | 26, 114, 129 |
| abstract_inverted_index.pressure | 15, 88, 95, 146, 169, 191, 251, 276 |
| abstract_inverted_index.randomly | 48 |
| abstract_inverted_index.reported | 212 |
| abstract_inverted_index.resulted | 140, 269 |
| abstract_inverted_index.surgery. | 19 |
| abstract_inverted_index.ureteral | 43 |
| abstract_inverted_index.variance | 188 |
| abstract_inverted_index.−0.15, | 255 |
| abstract_inverted_index.COMETTMII | 94 |
| abstract_inverted_index.Secondary | 67 |
| abstract_inverted_index.allocated | 47 |
| abstract_inverted_index.ascertain | 6 |
| abstract_inverted_index.closure). | 123 |
| abstract_inverted_index.correlate | 246 |
| abstract_inverted_index.developed | 263 |
| abstract_inverted_index.duration, | 80 |
| abstract_inverted_index.fluctuant | 274 |
| abstract_inverted_index.hand-pump | 56 |
| abstract_inverted_index.operating | 104 |
| abstract_inverted_index.outcomes. | 85 |
| abstract_inverted_index.performed | 91 |
| abstract_inverted_index.pressure, | 72 |
| abstract_inverted_index.pressure. | 66, 111 |
| abstract_inverted_index.procedure | 79 |
| abstract_inverted_index.recruited | 25 |
| abstract_inverted_index.technique | 11 |
| abstract_inverted_index.treatment | 39 |
| abstract_inverted_index.variance, | 73 |
| abstract_inverted_index.8.75(0.58) | 227 |
| abstract_inverted_index.Background | 1 |
| abstract_inverted_index.Conclusion | 265 |
| abstract_inverted_index.Subjective | 240 |
| abstract_inverted_index.clearance, | 82 |
| abstract_inverted_index.difference | 155 |
| abstract_inverted_index.guidewire, | 96 |
| abstract_inverted_index.intrarenal | 14, 18, 34, 65, 71, 87, 110, 145, 168, 190, 250, 275 |
| abstract_inverted_index.irrigation | 10, 139, 225, 268 |
| abstract_inverted_index.monitoring | 89 |
| abstract_inverted_index.procedural | 64, 210 |
| abstract_inverted_index.randomized | 23, 116 |
| abstract_inverted_index.retrograde | 17, 33 |
| abstract_inverted_index.undergoing | 32 |
| abstract_inverted_index.urosepsis. | 264 |
| abstract_inverted_index.(6.23(1.59) | 194 |
| abstract_inverted_index.(mean(s.d.) | 147, 226 |
| abstract_inverted_index.4.60(1.30); | 196 |
| abstract_inverted_index.6.28(1.27); | 229 |
| abstract_inverted_index.irrigation, | 137 |
| abstract_inverted_index.irrigation. | 58, 285 |
| abstract_inverted_index.transmitted | 249 |
| abstract_inverted_index.38.16(16.84) | 150 |
| abstract_inverted_index.62.29(27.45) | 148 |
| abstract_inverted_index.68.04(24.16) | 172 |
| abstract_inverted_index.Registration | 286 |
| abstract_inverted_index.Thirty-eight | 113 |
| abstract_inverted_index.osf.io/jmg2h | 288 |
| abstract_inverted_index.satisfaction | 208 |
| abstract_inverted_index.transformed) | 193 |
| abstract_inverted_index.significantly | 142, 247 |
| abstract_inverted_index.visualization, | 74 |
| abstract_inverted_index.(192.71(106.23) | 170 |
| abstract_inverted_index.cystoscopically | 98 |
| abstract_inverted_index.pressurized-bag | 52 |
| abstract_inverted_index.(https://osf.io/). | 289 |
| cited_by_percentile_year.max | 100 |
| cited_by_percentile_year.min | 99 |
| corresponding_author_ids | https://openalex.org/A5076947898 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 10 |
| corresponding_institution_ids | https://openalex.org/I142762351 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.4099999964237213 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.97425481 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |