Intravenous Thrombolytic Therapy for Acute Nonarteritic Central Retinal Artery Occlusion. A Review Article Swipe
Kamila Janská
,
Radek Bodnár
,
Petr Janský
,
Milan R. Voško
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.31348/2021/32
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.31348/2021/32
Central retinal artery occlusion (CRAO) is a form of acute ischemic stroke. It is a critical condition that often leads to severe visual loss or blindness and can be a harbinger of further cerebrovascular events. Due to the lack of scientific data, there are no effective evidence-based forms of therapy for this condition. None of the conservative therapies have proven effective. The results of some previously published studies suggest a benefit of intravenous thrombolytic therapy in the same regimen as in the treatment of ischemic stroke. This work aims to present an overview of published clinical studies focused on the use of intravenous thrombolysis for CRAO, evaluate its efficacy and safety, and propose an optimal diagnostic and therapeutic algorithm for acute management of CRAO. Summary statistics of patient data from relevant studies indicate that a significant visual acuity improvement was achieved by a total of 45 % of patients receiving alteplase within 4.5 hours of symptoms onset. The occurrence of adverse events in this time window was not significant. Intravenous thrombolytic therapy in CRAO thus appears to be effective and safe. However, we still lack data from adequate prospective randomized controlled trials to confirm this conclusion. To date, two randomized trials are being conducted. The intravenous thrombolysis administration, patient monitoring, etiologic workup, and setting of effective secondary prevention should be ensured at the centre of highly specialized cerebrovascular care. Urgent transport of the CRAO patient to the nearest centre is essential.
Related Topics
Concepts
Central retinal artery occlusion
Medicine
Thrombolysis
Randomized controlled trial
Fibrinolytic agent
Stroke (engine)
Adverse effect
Visual acuity
Clinical trial
Intensive care medicine
Surgery
Tissue plasminogen activator
Cardiology
Internal medicine
Myocardial infarction
Mechanical engineering
Engineering
Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.31348/2021/32
- https://www.cs-ophthalmology.cz/en/journal/3/articles/220/dl/823
- OA Status
- bronze
- Cited By
- 6
- References
- 54
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4213461265
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4213461265Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.31348/2021/32Digital Object Identifier
- Title
-
Intravenous Thrombolytic Therapy for Acute Nonarteritic Central Retinal Artery Occlusion. A ReviewWork title
- Type
-
reviewOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2022Year of publication
- Publication date
-
2022-05-16Full publication date if available
- Authors
-
Kamila Janská, Radek Bodnár, Petr Janský, Milan R. VoškoList of authors in order
- Landing page
-
https://doi.org/10.31348/2021/32Publisher landing page
- PDF URL
-
https://www.cs-ophthalmology.cz/en/journal/3/articles/220/dl/823Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
bronzeOpen access status per OpenAlex
- OA URL
-
https://www.cs-ophthalmology.cz/en/journal/3/articles/220/dl/823Direct OA link when available
- Concepts
-
Central retinal artery occlusion, Medicine, Thrombolysis, Randomized controlled trial, Fibrinolytic agent, Stroke (engine), Adverse effect, Visual acuity, Clinical trial, Intensive care medicine, Surgery, Tissue plasminogen activator, Cardiology, Internal medicine, Myocardial infarction, Mechanical engineering, EngineeringTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
6Total citation count in OpenAlex
- Citations by year (recent)
-
2024: 3, 2023: 2, 2022: 1Per-year citation counts (last 5 years)
- References (count)
-
54Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4213461265 |
|---|---|
| doi | https://doi.org/10.31348/2021/32 |
| ids.doi | https://doi.org/10.31348/2021/32 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/35760581 |
| ids.openalex | https://openalex.org/W4213461265 |
| fwci | 1.68942461 |
| mesh[0].qualifier_ui | Q000627 |
| mesh[0].descriptor_ui | D005343 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | therapeutic use |
| mesh[0].descriptor_name | Fibrinolytic Agents |
| mesh[1].qualifier_ui | |
| mesh[1].descriptor_ui | D006801 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | |
| mesh[1].descriptor_name | Humans |
| mesh[2].qualifier_ui | |
| mesh[2].descriptor_ui | D000083242 |
| mesh[2].is_major_topic | True |
| mesh[2].qualifier_name | |
| mesh[2].descriptor_name | Ischemic Stroke |
| mesh[3].qualifier_ui | |
| mesh[3].descriptor_ui | D011446 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | |
| mesh[3].descriptor_name | Prospective Studies |
| mesh[4].qualifier_ui | Q000188 |
| mesh[4].descriptor_ui | D015356 |
| mesh[4].is_major_topic | True |
| mesh[4].qualifier_name | drug therapy |
| mesh[4].descriptor_name | Retinal Artery Occlusion |
| mesh[5].qualifier_ui | Q000009 |
| mesh[5].descriptor_ui | D015912 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | adverse effects |
| mesh[5].descriptor_name | Thrombolytic Therapy |
| mesh[6].qualifier_ui | Q000379 |
| mesh[6].descriptor_ui | D015912 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | methods |
| mesh[6].descriptor_name | Thrombolytic Therapy |
| mesh[7].qualifier_ui | Q000627 |
| mesh[7].descriptor_ui | D005343 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | therapeutic use |
| mesh[7].descriptor_name | Fibrinolytic Agents |
| mesh[8].qualifier_ui | |
| mesh[8].descriptor_ui | D006801 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | |
| mesh[8].descriptor_name | Humans |
| mesh[9].qualifier_ui | |
| mesh[9].descriptor_ui | D000083242 |
| mesh[9].is_major_topic | True |
| mesh[9].qualifier_name | |
| mesh[9].descriptor_name | Ischemic Stroke |
| mesh[10].qualifier_ui | |
| mesh[10].descriptor_ui | D011446 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | |
| mesh[10].descriptor_name | Prospective Studies |
| mesh[11].qualifier_ui | Q000188 |
| mesh[11].descriptor_ui | D015356 |
| mesh[11].is_major_topic | True |
| mesh[11].qualifier_name | drug therapy |
| mesh[11].descriptor_name | Retinal Artery Occlusion |
| mesh[12].qualifier_ui | Q000009 |
| mesh[12].descriptor_ui | D015912 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | adverse effects |
| mesh[12].descriptor_name | Thrombolytic Therapy |
| mesh[13].qualifier_ui | Q000379 |
| mesh[13].descriptor_ui | D015912 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | methods |
| mesh[13].descriptor_name | Thrombolytic Therapy |
| type | review |
| title | Intravenous Thrombolytic Therapy for Acute Nonarteritic Central Retinal Artery Occlusion. A Review |
| biblio.issue | 3 |
| biblio.volume | 78 |
| biblio.last_page | 109 |
| biblio.first_page | 101 |
| topics[0].id | https://openalex.org/T12599 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 1.0 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2731 |
| topics[0].subfield.display_name | Ophthalmology |
| topics[0].display_name | Retinal and Optic Conditions |
| topics[1].id | https://openalex.org/T10227 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9947999715805054 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2713 |
| topics[1].subfield.display_name | Epidemiology |
| topics[1].display_name | Acute Ischemic Stroke Management |
| topics[2].id | https://openalex.org/T11194 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9941999912261963 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2731 |
| topics[2].subfield.display_name | Ophthalmology |
| topics[2].display_name | Ocular Diseases and Behçet’s Syndrome |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C2776449918 |
| concepts[0].level | 3 |
| concepts[0].score | 0.9545326232910156 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q3348620 |
| concepts[0].display_name | Central retinal artery occlusion |
| concepts[1].id | https://openalex.org/C71924100 |
| concepts[1].level | 0 |
| concepts[1].score | 0.9405261278152466 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[1].display_name | Medicine |
| concepts[2].id | https://openalex.org/C2779581417 |
| concepts[2].level | 3 |
| concepts[2].score | 0.7435699105262756 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q1931577 |
| concepts[2].display_name | Thrombolysis |
| concepts[3].id | https://openalex.org/C168563851 |
| concepts[3].level | 2 |
| concepts[3].score | 0.6134122610092163 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q1436668 |
| concepts[3].display_name | Randomized controlled trial |
| concepts[4].id | https://openalex.org/C2909817843 |
| concepts[4].level | 3 |
| concepts[4].score | 0.502598762512207 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q575222 |
| concepts[4].display_name | Fibrinolytic agent |
| concepts[5].id | https://openalex.org/C2780645631 |
| concepts[5].level | 2 |
| concepts[5].score | 0.5012280941009521 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q671554 |
| concepts[5].display_name | Stroke (engine) |
| concepts[6].id | https://openalex.org/C197934379 |
| concepts[6].level | 2 |
| concepts[6].score | 0.484210729598999 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q2047938 |
| concepts[6].display_name | Adverse effect |
| concepts[7].id | https://openalex.org/C2778257484 |
| concepts[7].level | 2 |
| concepts[7].score | 0.4712781310081482 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q555066 |
| concepts[7].display_name | Visual acuity |
| concepts[8].id | https://openalex.org/C535046627 |
| concepts[8].level | 2 |
| concepts[8].score | 0.4358729124069214 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q30612 |
| concepts[8].display_name | Clinical trial |
| concepts[9].id | https://openalex.org/C177713679 |
| concepts[9].level | 1 |
| concepts[9].score | 0.42752182483673096 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q679690 |
| concepts[9].display_name | Intensive care medicine |
| concepts[10].id | https://openalex.org/C141071460 |
| concepts[10].level | 1 |
| concepts[10].score | 0.3176279664039612 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q40821 |
| concepts[10].display_name | Surgery |
| concepts[11].id | https://openalex.org/C2776572282 |
| concepts[11].level | 2 |
| concepts[11].score | 0.2582154870033264 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q416351 |
| concepts[11].display_name | Tissue plasminogen activator |
| concepts[12].id | https://openalex.org/C164705383 |
| concepts[12].level | 1 |
| concepts[12].score | 0.1647186577320099 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q10379 |
| concepts[12].display_name | Cardiology |
| concepts[13].id | https://openalex.org/C126322002 |
| concepts[13].level | 1 |
| concepts[13].score | 0.16462871432304382 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[13].display_name | Internal medicine |
| concepts[14].id | https://openalex.org/C500558357 |
| concepts[14].level | 2 |
| concepts[14].score | 0.15768632292747498 |
| concepts[14].wikidata | https://www.wikidata.org/wiki/Q12152 |
| concepts[14].display_name | Myocardial infarction |
| concepts[15].id | https://openalex.org/C78519656 |
| concepts[15].level | 1 |
| concepts[15].score | 0.0 |
| concepts[15].wikidata | https://www.wikidata.org/wiki/Q101333 |
| concepts[15].display_name | Mechanical engineering |
| concepts[16].id | https://openalex.org/C127413603 |
| concepts[16].level | 0 |
| concepts[16].score | 0.0 |
| concepts[16].wikidata | https://www.wikidata.org/wiki/Q11023 |
| concepts[16].display_name | Engineering |
| keywords[0].id | https://openalex.org/keywords/central-retinal-artery-occlusion |
| keywords[0].score | 0.9545326232910156 |
| keywords[0].display_name | Central retinal artery occlusion |
| keywords[1].id | https://openalex.org/keywords/medicine |
| keywords[1].score | 0.9405261278152466 |
| keywords[1].display_name | Medicine |
| keywords[2].id | https://openalex.org/keywords/thrombolysis |
| keywords[2].score | 0.7435699105262756 |
| keywords[2].display_name | Thrombolysis |
| keywords[3].id | https://openalex.org/keywords/randomized-controlled-trial |
| keywords[3].score | 0.6134122610092163 |
| keywords[3].display_name | Randomized controlled trial |
| keywords[4].id | https://openalex.org/keywords/fibrinolytic-agent |
| keywords[4].score | 0.502598762512207 |
| keywords[4].display_name | Fibrinolytic agent |
| keywords[5].id | https://openalex.org/keywords/stroke |
| keywords[5].score | 0.5012280941009521 |
| keywords[5].display_name | Stroke (engine) |
| keywords[6].id | https://openalex.org/keywords/adverse-effect |
| keywords[6].score | 0.484210729598999 |
| keywords[6].display_name | Adverse effect |
| keywords[7].id | https://openalex.org/keywords/visual-acuity |
| keywords[7].score | 0.4712781310081482 |
| keywords[7].display_name | Visual acuity |
| keywords[8].id | https://openalex.org/keywords/clinical-trial |
| keywords[8].score | 0.4358729124069214 |
| keywords[8].display_name | Clinical trial |
| keywords[9].id | https://openalex.org/keywords/intensive-care-medicine |
| keywords[9].score | 0.42752182483673096 |
| keywords[9].display_name | Intensive care medicine |
| keywords[10].id | https://openalex.org/keywords/surgery |
| keywords[10].score | 0.3176279664039612 |
| keywords[10].display_name | Surgery |
| keywords[11].id | https://openalex.org/keywords/tissue-plasminogen-activator |
| keywords[11].score | 0.2582154870033264 |
| keywords[11].display_name | Tissue plasminogen activator |
| keywords[12].id | https://openalex.org/keywords/cardiology |
| keywords[12].score | 0.1647186577320099 |
| keywords[12].display_name | Cardiology |
| keywords[13].id | https://openalex.org/keywords/internal-medicine |
| keywords[13].score | 0.16462871432304382 |
| keywords[13].display_name | Internal medicine |
| keywords[14].id | https://openalex.org/keywords/myocardial-infarction |
| keywords[14].score | 0.15768632292747498 |
| keywords[14].display_name | Myocardial infarction |
| language | en |
| locations[0].id | doi:10.31348/2021/32 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S2754987326 |
| locations[0].source.issn | 1211-9059, 1805-4447 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 1211-9059 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Czech and Slovak Ophthalmology |
| locations[0].source.host_organization | https://openalex.org/P4310314279 |
| locations[0].source.host_organization_name | Czech Medical Association of J. E. Purkyně |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310314279 |
| locations[0].license | |
| locations[0].pdf_url | https://www.cs-ophthalmology.cz/en/journal/3/articles/220/dl/823 |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Czech and Slovak Ophthalmology |
| locations[0].landing_page_url | https://doi.org/10.31348/2021/32 |
| locations[1].id | pmid:35760581 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/35760581 |
| indexed_in | crossref, pubmed |
| authorships[0].author.id | https://openalex.org/A5081529832 |
| authorships[0].author.orcid | |
| authorships[0].author.display_name | Kamila Janská |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Kamila Janská |
| authorships[0].is_corresponding | False |
| authorships[1].author.id | https://openalex.org/A5083175047 |
| authorships[1].author.orcid | |
| authorships[1].author.display_name | Radek Bodnár |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Radek Bodnár |
| authorships[1].is_corresponding | False |
| authorships[2].author.id | https://openalex.org/A5107857922 |
| authorships[2].author.orcid | |
| authorships[2].author.display_name | Petr Janský |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Petr Janský |
| authorships[2].is_corresponding | False |
| authorships[3].author.id | https://openalex.org/A5077568291 |
| authorships[3].author.orcid | https://orcid.org/0000-0003-3270-3459 |
| authorships[3].author.display_name | Milan R. Voško |
| authorships[3].author_position | last |
| authorships[3].raw_author_name | Milan Vosko |
| authorships[3].is_corresponding | False |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.cs-ophthalmology.cz/en/journal/3/articles/220/dl/823 |
| open_access.oa_status | bronze |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Intravenous Thrombolytic Therapy for Acute Nonarteritic Central Retinal Artery Occlusion. A Review |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T12599 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 1.0 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2731 |
| primary_topic.subfield.display_name | Ophthalmology |
| primary_topic.display_name | Retinal and Optic Conditions |
| related_works | https://openalex.org/W3030252198, https://openalex.org/W1994791755, https://openalex.org/W2405781164, https://openalex.org/W2374020487, https://openalex.org/W2079785147, https://openalex.org/W3151136523, https://openalex.org/W3046854717, https://openalex.org/W3177981495, https://openalex.org/W2112328442, https://openalex.org/W3191033586 |
| cited_by_count | 6 |
| counts_by_year[0].year | 2024 |
| counts_by_year[0].cited_by_count | 3 |
| counts_by_year[1].year | 2023 |
| counts_by_year[1].cited_by_count | 2 |
| counts_by_year[2].year | 2022 |
| counts_by_year[2].cited_by_count | 1 |
| locations_count | 2 |
| best_oa_location.id | doi:10.31348/2021/32 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2754987326 |
| best_oa_location.source.issn | 1211-9059, 1805-4447 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | 1211-9059 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | Czech and Slovak Ophthalmology |
| best_oa_location.source.host_organization | https://openalex.org/P4310314279 |
| best_oa_location.source.host_organization_name | Czech Medical Association of J. E. Purkyně |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310314279 |
| best_oa_location.license | |
| best_oa_location.pdf_url | https://www.cs-ophthalmology.cz/en/journal/3/articles/220/dl/823 |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Czech and Slovak Ophthalmology |
| best_oa_location.landing_page_url | https://doi.org/10.31348/2021/32 |
| primary_location.id | doi:10.31348/2021/32 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S2754987326 |
| primary_location.source.issn | 1211-9059, 1805-4447 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 1211-9059 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Czech and Slovak Ophthalmology |
| primary_location.source.host_organization | https://openalex.org/P4310314279 |
| primary_location.source.host_organization_name | Czech Medical Association of J. E. Purkyně |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310314279 |
| primary_location.license | |
| primary_location.pdf_url | https://www.cs-ophthalmology.cz/en/journal/3/articles/220/dl/823 |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Czech and Slovak Ophthalmology |
| primary_location.landing_page_url | https://doi.org/10.31348/2021/32 |
| publication_date | 2022-05-16 |
| publication_year | 2022 |
| referenced_works | https://openalex.org/W1971502700, https://openalex.org/W1512449216, https://openalex.org/W2005984404, https://openalex.org/W2121844172, https://openalex.org/W1971835723, https://openalex.org/W3046854717, https://openalex.org/W1512538211, https://openalex.org/W4243499698, https://openalex.org/W1525856606, https://openalex.org/W4229671962, https://openalex.org/W2003391728, https://openalex.org/W2772146494, https://openalex.org/W4241370100, https://openalex.org/W2074010290, https://openalex.org/W4243593832, https://openalex.org/W2051694673, https://openalex.org/W2137042108, https://openalex.org/W2154754683, https://openalex.org/W2569848705, https://openalex.org/W2805387104, https://openalex.org/W3120842896, https://openalex.org/W2168320449, https://openalex.org/W2061503606, https://openalex.org/W2998369087, https://openalex.org/W2023404555, https://openalex.org/W2090544309, https://openalex.org/W1986524273, https://openalex.org/W2944491145, https://openalex.org/W2945717944, https://openalex.org/W2767776410, https://openalex.org/W2787867590, https://openalex.org/W2803802119, https://openalex.org/W2911361393, https://openalex.org/W1531488791, https://openalex.org/W1773968258, https://openalex.org/W2006619963, https://openalex.org/W1979273852, https://openalex.org/W2056339360, https://openalex.org/W2089707598, https://openalex.org/W2142652399, https://openalex.org/W2138595885, https://openalex.org/W2805507173, https://openalex.org/W2147797899, https://openalex.org/W2333959929, https://openalex.org/W3005639861, https://openalex.org/W2147474587, https://openalex.org/W2137262471, https://openalex.org/W2085443645, https://openalex.org/W4248971365, https://openalex.org/W15025138, https://openalex.org/W3094820639, https://openalex.org/W2516974783, https://openalex.org/W2159233098, https://openalex.org/W2576493654 |
| referenced_works_count | 54 |
| abstract_inverted_index.% | 146 |
| abstract_inverted_index.a | 6, 14, 29, 69, 134, 142 |
| abstract_inverted_index.45 | 145 |
| abstract_inverted_index.It | 12 |
| abstract_inverted_index.To | 196 |
| abstract_inverted_index.an | 91, 113 |
| abstract_inverted_index.as | 79 |
| abstract_inverted_index.at | 221 |
| abstract_inverted_index.be | 28, 177, 219 |
| abstract_inverted_index.by | 141 |
| abstract_inverted_index.in | 75, 80, 162, 172 |
| abstract_inverted_index.is | 5, 13, 239 |
| abstract_inverted_index.no | 44 |
| abstract_inverted_index.of | 8, 31, 39, 48, 54, 63, 71, 83, 93, 101, 122, 126, 144, 147, 154, 159, 214, 224, 231 |
| abstract_inverted_index.on | 98 |
| abstract_inverted_index.or | 24 |
| abstract_inverted_index.to | 20, 36, 89, 176, 192, 235 |
| abstract_inverted_index.we | 182 |
| abstract_inverted_index.4.5 | 152 |
| abstract_inverted_index.Due | 35 |
| abstract_inverted_index.The | 61, 157, 204 |
| abstract_inverted_index.and | 26, 109, 111, 116, 179, 212 |
| abstract_inverted_index.are | 43, 201 |
| abstract_inverted_index.can | 27 |
| abstract_inverted_index.for | 50, 104, 119 |
| abstract_inverted_index.its | 107 |
| abstract_inverted_index.not | 167 |
| abstract_inverted_index.the | 37, 55, 76, 81, 99, 222, 232, 236 |
| abstract_inverted_index.two | 198 |
| abstract_inverted_index.use | 100 |
| abstract_inverted_index.was | 139, 166 |
| abstract_inverted_index.CRAO | 173, 233 |
| abstract_inverted_index.None | 53 |
| abstract_inverted_index.This | 86 |
| abstract_inverted_index.aims | 88 |
| abstract_inverted_index.data | 128, 185 |
| abstract_inverted_index.form | 7 |
| abstract_inverted_index.from | 129, 186 |
| abstract_inverted_index.have | 58 |
| abstract_inverted_index.lack | 38, 184 |
| abstract_inverted_index.loss | 23 |
| abstract_inverted_index.same | 77 |
| abstract_inverted_index.some | 64 |
| abstract_inverted_index.that | 17, 133 |
| abstract_inverted_index.this | 51, 163, 194 |
| abstract_inverted_index.thus | 174 |
| abstract_inverted_index.time | 164 |
| abstract_inverted_index.work | 87 |
| abstract_inverted_index.CRAO, | 105 |
| abstract_inverted_index.CRAO. | 123 |
| abstract_inverted_index.acute | 9, 120 |
| abstract_inverted_index.being | 202 |
| abstract_inverted_index.care. | 228 |
| abstract_inverted_index.data, | 41 |
| abstract_inverted_index.date, | 197 |
| abstract_inverted_index.forms | 47 |
| abstract_inverted_index.hours | 153 |
| abstract_inverted_index.leads | 19 |
| abstract_inverted_index.often | 18 |
| abstract_inverted_index.safe. | 180 |
| abstract_inverted_index.still | 183 |
| abstract_inverted_index.there | 42 |
| abstract_inverted_index.total | 143 |
| abstract_inverted_index.(CRAO) | 4 |
| abstract_inverted_index.Urgent | 229 |
| abstract_inverted_index.acuity | 137 |
| abstract_inverted_index.artery | 2 |
| abstract_inverted_index.centre | 223, 238 |
| abstract_inverted_index.events | 161 |
| abstract_inverted_index.highly | 225 |
| abstract_inverted_index.onset. | 156 |
| abstract_inverted_index.proven | 59 |
| abstract_inverted_index.severe | 21 |
| abstract_inverted_index.should | 218 |
| abstract_inverted_index.trials | 191, 200 |
| abstract_inverted_index.visual | 22, 136 |
| abstract_inverted_index.window | 165 |
| abstract_inverted_index.within | 151 |
| abstract_inverted_index.Central | 0 |
| abstract_inverted_index.Summary | 124 |
| abstract_inverted_index.adverse | 160 |
| abstract_inverted_index.appears | 175 |
| abstract_inverted_index.benefit | 70 |
| abstract_inverted_index.confirm | 193 |
| abstract_inverted_index.ensured | 220 |
| abstract_inverted_index.events. | 34 |
| abstract_inverted_index.focused | 97 |
| abstract_inverted_index.further | 32 |
| abstract_inverted_index.nearest | 237 |
| abstract_inverted_index.optimal | 114 |
| abstract_inverted_index.patient | 127, 208, 234 |
| abstract_inverted_index.present | 90 |
| abstract_inverted_index.propose | 112 |
| abstract_inverted_index.regimen | 78 |
| abstract_inverted_index.results | 62 |
| abstract_inverted_index.retinal | 1 |
| abstract_inverted_index.safety, | 110 |
| abstract_inverted_index.setting | 213 |
| abstract_inverted_index.stroke. | 11, 85 |
| abstract_inverted_index.studies | 67, 96, 131 |
| abstract_inverted_index.suggest | 68 |
| abstract_inverted_index.therapy | 49, 74, 171 |
| abstract_inverted_index.workup, | 211 |
| abstract_inverted_index.However, | 181 |
| abstract_inverted_index.achieved | 140 |
| abstract_inverted_index.adequate | 187 |
| abstract_inverted_index.clinical | 95 |
| abstract_inverted_index.critical | 15 |
| abstract_inverted_index.efficacy | 108 |
| abstract_inverted_index.evaluate | 106 |
| abstract_inverted_index.indicate | 132 |
| abstract_inverted_index.ischemic | 10, 84 |
| abstract_inverted_index.overview | 92 |
| abstract_inverted_index.patients | 148 |
| abstract_inverted_index.relevant | 130 |
| abstract_inverted_index.symptoms | 155 |
| abstract_inverted_index.algorithm | 118 |
| abstract_inverted_index.alteplase | 150 |
| abstract_inverted_index.blindness | 25 |
| abstract_inverted_index.condition | 16 |
| abstract_inverted_index.effective | 45, 178, 215 |
| abstract_inverted_index.etiologic | 210 |
| abstract_inverted_index.harbinger | 30 |
| abstract_inverted_index.occlusion | 3 |
| abstract_inverted_index.published | 66, 94 |
| abstract_inverted_index.receiving | 149 |
| abstract_inverted_index.secondary | 216 |
| abstract_inverted_index.therapies | 57 |
| abstract_inverted_index.transport | 230 |
| abstract_inverted_index.treatment | 82 |
| abstract_inverted_index.condition. | 52 |
| abstract_inverted_index.conducted. | 203 |
| abstract_inverted_index.controlled | 190 |
| abstract_inverted_index.diagnostic | 115 |
| abstract_inverted_index.effective. | 60 |
| abstract_inverted_index.essential. | 240 |
| abstract_inverted_index.management | 121 |
| abstract_inverted_index.occurrence | 158 |
| abstract_inverted_index.prevention | 217 |
| abstract_inverted_index.previously | 65 |
| abstract_inverted_index.randomized | 189, 199 |
| abstract_inverted_index.scientific | 40 |
| abstract_inverted_index.statistics | 125 |
| abstract_inverted_index.Intravenous | 169 |
| abstract_inverted_index.conclusion. | 195 |
| abstract_inverted_index.improvement | 138 |
| abstract_inverted_index.intravenous | 72, 102, 205 |
| abstract_inverted_index.monitoring, | 209 |
| abstract_inverted_index.prospective | 188 |
| abstract_inverted_index.significant | 135 |
| abstract_inverted_index.specialized | 226 |
| abstract_inverted_index.therapeutic | 117 |
| abstract_inverted_index.conservative | 56 |
| abstract_inverted_index.significant. | 168 |
| abstract_inverted_index.thrombolysis | 103, 206 |
| abstract_inverted_index.thrombolytic | 73, 170 |
| abstract_inverted_index.evidence-based | 46 |
| abstract_inverted_index.administration, | 207 |
| abstract_inverted_index.cerebrovascular | 33, 227 |
| cited_by_percentile_year.max | 97 |
| cited_by_percentile_year.min | 89 |
| countries_distinct_count | 0 |
| institutions_distinct_count | 4 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.7900000214576721 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.76675065 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |