Intrinsically disordered regions regulate RhlE RNA helicase functions in bacteria Article Swipe
Stéphane Hausmann
,
Johan Geiser
,
George E. Allen
,
Sandra Amandine Marie Geslain
,
Martina Valentini
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1093/nar/gkae511
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1093/nar/gkae511
RNA helicases—central enzymes in RNA metabolism—often feature intrinsically disordered regions (IDRs) that enable phase separation and complex molecular interactions. In the bacterial pathogen Pseudomonas aeruginosa, the non-redundant RhlE1 and RhlE2 RNA helicases share a conserved REC catalytic core but differ in C-terminal IDRs. Here, we show how the IDR diversity defines RhlE RNA helicase specificity of function. Both IDRs facilitate RNA binding and phase separation, localizing proteins in cytoplasmic clusters. However, RhlE2 IDR is more efficient in enhancing REC core RNA unwinding, exhibits a greater tendency for phase separation, and interacts with the RNase E endonuclease, a crucial player in mRNA degradation. Swapping IDRs results in chimeric proteins that are biochemically active but functionally distinct as compared to their native counterparts. The RECRhlE1-IDRRhlE2 chimera improves cold growth of a rhlE1 mutant, gains interaction with RNase E and affects a subset of both RhlE1 and RhlE2 RNA targets. The RECRhlE2-IDRRhlE1 chimera instead hampers bacterial growth at low temperatures in the absence of RhlE1, with its detrimental effect linked to aberrant RNA droplets. By showing that IDRs modulate both protein core activities and subcellular localization, our study defines the impact of IDR diversity on the functional differentiation of RNA helicases.
Related Topics
Concepts
Biology
Helicase
RNA
RNase P
Exosome complex
RNA Helicase A
Degradosome
RNA silencing
RNA-binding protein
Cell biology
Non-coding RNA
Riboswitch
Genetics
Gene
RNA interference
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/nar/gkae511
- https://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gkae511/58234502/gkae511.pdf
- OA Status
- gold
- Cited By
- 5
- References
- 79
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4399671295
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4399671295Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1093/nar/gkae511Digital Object Identifier
- Title
-
Intrinsically disordered regions regulate RhlE RNA helicase functions in bacteriaWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-06-03Full publication date if available
- Authors
-
Stéphane Hausmann, Johan Geiser, George E. Allen, Sandra Amandine Marie Geslain, Martina ValentiniList of authors in order
- Landing page
-
https://doi.org/10.1093/nar/gkae511Publisher landing page
- PDF URL
-
https://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gkae511/58234502/gkae511.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gkae511/58234502/gkae511.pdfDirect OA link when available
- Concepts
-
Biology, Helicase, RNA, RNase P, Exosome complex, RNA Helicase A, Degradosome, RNA silencing, RNA-binding protein, Cell biology, Non-coding RNA, Riboswitch, Genetics, Gene, RNA interferenceTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
5Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 4, 2024: 1Per-year citation counts (last 5 years)
- References (count)
-
79Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4399671295 |
|---|---|
| doi | https://doi.org/10.1093/nar/gkae511 |
| ids.doi | https://doi.org/10.1093/nar/gkae511 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/38874491 |
| ids.openalex | https://openalex.org/W4399671295 |
| fwci | 2.40123613 |
| mesh[0].qualifier_ui | Q000378 |
| mesh[0].descriptor_ui | D020365 |
| mesh[0].is_major_topic | True |
| mesh[0].qualifier_name | metabolism |
| mesh[0].descriptor_name | RNA Helicases |
| mesh[1].qualifier_ui | Q000235 |
| mesh[1].descriptor_ui | D020365 |
| mesh[1].is_major_topic | True |
| mesh[1].qualifier_name | genetics |
| mesh[1].descriptor_name | RNA Helicases |
| mesh[2].qualifier_ui | Q000737 |
| mesh[2].descriptor_ui | D020365 |
| mesh[2].is_major_topic | True |
| mesh[2].qualifier_name | chemistry |
| mesh[2].descriptor_name | RNA Helicases |
| mesh[3].qualifier_ui | Q000378 |
| mesh[3].descriptor_ui | D001426 |
| mesh[3].is_major_topic | True |
| mesh[3].qualifier_name | metabolism |
| mesh[3].descriptor_name | Bacterial Proteins |
| mesh[4].qualifier_ui | Q000235 |
| mesh[4].descriptor_ui | D001426 |
| mesh[4].is_major_topic | True |
| mesh[4].qualifier_name | genetics |
| mesh[4].descriptor_name | Bacterial Proteins |
| mesh[5].qualifier_ui | Q000737 |
| mesh[5].descriptor_ui | D001426 |
| mesh[5].is_major_topic | True |
| mesh[5].qualifier_name | chemistry |
| mesh[5].descriptor_name | Bacterial Proteins |
| mesh[6].qualifier_ui | Q000378 |
| mesh[6].descriptor_ui | D004722 |
| mesh[6].is_major_topic | True |
| mesh[6].qualifier_name | metabolism |
| mesh[6].descriptor_name | Endoribonucleases |
| mesh[7].qualifier_ui | Q000737 |
| mesh[7].descriptor_ui | D004722 |
| mesh[7].is_major_topic | True |
| mesh[7].qualifier_name | chemistry |
| mesh[7].descriptor_name | Endoribonucleases |
| mesh[8].qualifier_ui | Q000235 |
| mesh[8].descriptor_ui | D004722 |
| mesh[8].is_major_topic | True |
| mesh[8].qualifier_name | genetics |
| mesh[8].descriptor_name | Endoribonucleases |
| mesh[9].qualifier_ui | Q000378 |
| mesh[9].descriptor_ui | D064267 |
| mesh[9].is_major_topic | True |
| mesh[9].qualifier_name | metabolism |
| mesh[9].descriptor_name | Intrinsically Disordered Proteins |
| mesh[10].qualifier_ui | Q000737 |
| mesh[10].descriptor_ui | D064267 |
| mesh[10].is_major_topic | True |
| mesh[10].qualifier_name | chemistry |
| mesh[10].descriptor_name | Intrinsically Disordered Proteins |
| mesh[11].qualifier_ui | Q000235 |
| mesh[11].descriptor_ui | D064267 |
| mesh[11].is_major_topic | True |
| mesh[11].qualifier_name | genetics |
| mesh[11].descriptor_name | Intrinsically Disordered Proteins |
| mesh[12].qualifier_ui | Q000201 |
| mesh[12].descriptor_ui | D011550 |
| mesh[12].is_major_topic | True |
| mesh[12].qualifier_name | enzymology |
| mesh[12].descriptor_name | Pseudomonas aeruginosa |
| mesh[13].qualifier_ui | Q000235 |
| mesh[13].descriptor_ui | D011550 |
| mesh[13].is_major_topic | True |
| mesh[13].qualifier_name | genetics |
| mesh[13].descriptor_name | Pseudomonas aeruginosa |
| mesh[14].qualifier_ui | |
| mesh[14].descriptor_ui | D011485 |
| mesh[14].is_major_topic | False |
| mesh[14].qualifier_name | |
| mesh[14].descriptor_name | Protein Binding |
| mesh[15].qualifier_ui | Q000378 |
| mesh[15].descriptor_ui | D020365 |
| mesh[15].is_major_topic | True |
| mesh[15].qualifier_name | metabolism |
| mesh[15].descriptor_name | RNA Helicases |
| mesh[16].qualifier_ui | Q000235 |
| mesh[16].descriptor_ui | D020365 |
| mesh[16].is_major_topic | True |
| mesh[16].qualifier_name | genetics |
| mesh[16].descriptor_name | RNA Helicases |
| mesh[17].qualifier_ui | Q000737 |
| mesh[17].descriptor_ui | D020365 |
| mesh[17].is_major_topic | True |
| mesh[17].qualifier_name | chemistry |
| mesh[17].descriptor_name | RNA Helicases |
| mesh[18].qualifier_ui | Q000378 |
| mesh[18].descriptor_ui | D001426 |
| mesh[18].is_major_topic | True |
| mesh[18].qualifier_name | metabolism |
| mesh[18].descriptor_name | Bacterial Proteins |
| mesh[19].qualifier_ui | Q000235 |
| mesh[19].descriptor_ui | D001426 |
| mesh[19].is_major_topic | True |
| mesh[19].qualifier_name | genetics |
| mesh[19].descriptor_name | Bacterial Proteins |
| mesh[20].qualifier_ui | Q000737 |
| mesh[20].descriptor_ui | D001426 |
| mesh[20].is_major_topic | True |
| mesh[20].qualifier_name | chemistry |
| mesh[20].descriptor_name | Bacterial Proteins |
| mesh[21].qualifier_ui | Q000378 |
| mesh[21].descriptor_ui | D004722 |
| mesh[21].is_major_topic | True |
| mesh[21].qualifier_name | metabolism |
| mesh[21].descriptor_name | Endoribonucleases |
| mesh[22].qualifier_ui | Q000737 |
| mesh[22].descriptor_ui | D004722 |
| mesh[22].is_major_topic | True |
| mesh[22].qualifier_name | chemistry |
| mesh[22].descriptor_name | Endoribonucleases |
| mesh[23].qualifier_ui | Q000235 |
| mesh[23].descriptor_ui | D004722 |
| mesh[23].is_major_topic | True |
| mesh[23].qualifier_name | genetics |
| mesh[23].descriptor_name | Endoribonucleases |
| mesh[24].qualifier_ui | Q000378 |
| mesh[24].descriptor_ui | D064267 |
| mesh[24].is_major_topic | True |
| mesh[24].qualifier_name | metabolism |
| mesh[24].descriptor_name | Intrinsically Disordered Proteins |
| mesh[25].qualifier_ui | Q000737 |
| mesh[25].descriptor_ui | D064267 |
| mesh[25].is_major_topic | True |
| mesh[25].qualifier_name | chemistry |
| mesh[25].descriptor_name | Intrinsically Disordered Proteins |
| mesh[26].qualifier_ui | Q000235 |
| mesh[26].descriptor_ui | D064267 |
| mesh[26].is_major_topic | True |
| mesh[26].qualifier_name | genetics |
| mesh[26].descriptor_name | Intrinsically Disordered Proteins |
| mesh[27].qualifier_ui | Q000201 |
| mesh[27].descriptor_ui | D011550 |
| mesh[27].is_major_topic | True |
| mesh[27].qualifier_name | enzymology |
| mesh[27].descriptor_name | Pseudomonas aeruginosa |
| mesh[28].qualifier_ui | Q000235 |
| mesh[28].descriptor_ui | D011550 |
| mesh[28].is_major_topic | True |
| mesh[28].qualifier_name | genetics |
| mesh[28].descriptor_name | Pseudomonas aeruginosa |
| mesh[29].qualifier_ui | |
| mesh[29].descriptor_ui | D011485 |
| mesh[29].is_major_topic | False |
| mesh[29].qualifier_name | |
| mesh[29].descriptor_name | Protein Binding |
| mesh[30].qualifier_ui | Q000378 |
| mesh[30].descriptor_ui | D020365 |
| mesh[30].is_major_topic | True |
| mesh[30].qualifier_name | metabolism |
| mesh[30].descriptor_name | RNA Helicases |
| mesh[31].qualifier_ui | Q000235 |
| mesh[31].descriptor_ui | D020365 |
| mesh[31].is_major_topic | True |
| mesh[31].qualifier_name | genetics |
| mesh[31].descriptor_name | RNA Helicases |
| mesh[32].qualifier_ui | Q000737 |
| mesh[32].descriptor_ui | D020365 |
| mesh[32].is_major_topic | True |
| mesh[32].qualifier_name | chemistry |
| mesh[32].descriptor_name | RNA Helicases |
| mesh[33].qualifier_ui | Q000378 |
| mesh[33].descriptor_ui | D001426 |
| mesh[33].is_major_topic | True |
| mesh[33].qualifier_name | metabolism |
| mesh[33].descriptor_name | Bacterial Proteins |
| mesh[34].qualifier_ui | Q000235 |
| mesh[34].descriptor_ui | D001426 |
| mesh[34].is_major_topic | True |
| mesh[34].qualifier_name | genetics |
| mesh[34].descriptor_name | Bacterial Proteins |
| mesh[35].qualifier_ui | Q000737 |
| mesh[35].descriptor_ui | D001426 |
| mesh[35].is_major_topic | True |
| mesh[35].qualifier_name | chemistry |
| mesh[35].descriptor_name | Bacterial Proteins |
| mesh[36].qualifier_ui | Q000378 |
| mesh[36].descriptor_ui | D004722 |
| mesh[36].is_major_topic | True |
| mesh[36].qualifier_name | metabolism |
| mesh[36].descriptor_name | Endoribonucleases |
| mesh[37].qualifier_ui | Q000737 |
| mesh[37].descriptor_ui | D004722 |
| mesh[37].is_major_topic | True |
| mesh[37].qualifier_name | chemistry |
| mesh[37].descriptor_name | Endoribonucleases |
| mesh[38].qualifier_ui | Q000235 |
| mesh[38].descriptor_ui | D004722 |
| mesh[38].is_major_topic | True |
| mesh[38].qualifier_name | genetics |
| mesh[38].descriptor_name | Endoribonucleases |
| mesh[39].qualifier_ui | Q000378 |
| mesh[39].descriptor_ui | D064267 |
| mesh[39].is_major_topic | True |
| mesh[39].qualifier_name | metabolism |
| mesh[39].descriptor_name | Intrinsically Disordered Proteins |
| mesh[40].qualifier_ui | Q000737 |
| mesh[40].descriptor_ui | D064267 |
| mesh[40].is_major_topic | True |
| mesh[40].qualifier_name | chemistry |
| mesh[40].descriptor_name | Intrinsically Disordered Proteins |
| mesh[41].qualifier_ui | Q000235 |
| mesh[41].descriptor_ui | D064267 |
| mesh[41].is_major_topic | True |
| mesh[41].qualifier_name | genetics |
| mesh[41].descriptor_name | Intrinsically Disordered Proteins |
| mesh[42].qualifier_ui | Q000201 |
| mesh[42].descriptor_ui | D011550 |
| mesh[42].is_major_topic | True |
| mesh[42].qualifier_name | enzymology |
| mesh[42].descriptor_name | Pseudomonas aeruginosa |
| mesh[43].qualifier_ui | Q000235 |
| mesh[43].descriptor_ui | D011550 |
| mesh[43].is_major_topic | True |
| mesh[43].qualifier_name | genetics |
| mesh[43].descriptor_name | Pseudomonas aeruginosa |
| mesh[44].qualifier_ui | |
| mesh[44].descriptor_ui | D011485 |
| mesh[44].is_major_topic | False |
| mesh[44].qualifier_name | |
| mesh[44].descriptor_name | Protein Binding |
| mesh[45].qualifier_ui | Q000378 |
| mesh[45].descriptor_ui | D020365 |
| mesh[45].is_major_topic | True |
| mesh[45].qualifier_name | metabolism |
| mesh[45].descriptor_name | RNA Helicases |
| mesh[46].qualifier_ui | Q000235 |
| mesh[46].descriptor_ui | D020365 |
| mesh[46].is_major_topic | True |
| mesh[46].qualifier_name | genetics |
| mesh[46].descriptor_name | RNA Helicases |
| mesh[47].qualifier_ui | Q000737 |
| mesh[47].descriptor_ui | D020365 |
| mesh[47].is_major_topic | True |
| mesh[47].qualifier_name | chemistry |
| mesh[47].descriptor_name | RNA Helicases |
| mesh[48].qualifier_ui | Q000378 |
| mesh[48].descriptor_ui | D001426 |
| mesh[48].is_major_topic | True |
| mesh[48].qualifier_name | metabolism |
| mesh[48].descriptor_name | Bacterial Proteins |
| mesh[49].qualifier_ui | Q000235 |
| mesh[49].descriptor_ui | D001426 |
| mesh[49].is_major_topic | True |
| mesh[49].qualifier_name | genetics |
| mesh[49].descriptor_name | Bacterial Proteins |
| type | article |
| title | Intrinsically disordered regions regulate RhlE RNA helicase functions in bacteria |
| awards[0].id | https://openalex.org/G4150833367 |
| awards[0].funder_id | https://openalex.org/F4320320924 |
| awards[0].display_name | |
| awards[0].funder_award_id | PCEFP3_203343 |
| awards[0].funder_display_name | Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung |
| biblio.issue | 13 |
| biblio.volume | 52 |
| biblio.last_page | 7824 |
| biblio.first_page | 7809 |
| topics[0].id | https://openalex.org/T10521 |
| topics[0].field.id | https://openalex.org/fields/13 |
| topics[0].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[0].score | 0.9997000098228455 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/1312 |
| topics[0].subfield.display_name | Molecular Biology |
| topics[0].display_name | RNA and protein synthesis mechanisms |
| topics[1].id | https://openalex.org/T10604 |
| topics[1].field.id | https://openalex.org/fields/13 |
| topics[1].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[1].score | 0.9991000294685364 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/1312 |
| topics[1].subfield.display_name | Molecular Biology |
| topics[1].display_name | RNA Research and Splicing |
| topics[2].id | https://openalex.org/T10120 |
| topics[2].field.id | https://openalex.org/fields/13 |
| topics[2].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[2].score | 0.9987999796867371 |
| topics[2].domain.id | https://openalex.org/domains/1 |
| topics[2].domain.display_name | Life Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/1311 |
| topics[2].subfield.display_name | Genetics |
| topics[2].display_name | Bacterial Genetics and Biotechnology |
| funders[0].id | https://openalex.org/F4320320924 |
| funders[0].ror | https://ror.org/00yjd3n13 |
| funders[0].display_name | Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung |
| funders[1].id | https://openalex.org/F4320327716 |
| funders[1].ror | |
| funders[1].display_name | Olga Mayenfisch Stiftung |
| funders[2].id | https://openalex.org/F4320331997 |
| funders[2].ror | |
| funders[2].display_name | Fondation Pierre Mercier pour la Science |
| is_xpac | False |
| apc_list.value | 3630 |
| apc_list.currency | USD |
| apc_list.value_usd | 3630 |
| apc_paid.value | 3228 |
| apc_paid.currency | EUR |
| apc_paid.value_usd | 3481 |
| concepts[0].id | https://openalex.org/C86803240 |
| concepts[0].level | 0 |
| concepts[0].score | 0.8435028791427612 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[0].display_name | Biology |
| concepts[1].id | https://openalex.org/C161223559 |
| concepts[1].level | 4 |
| concepts[1].score | 0.7854456901550293 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q138864 |
| concepts[1].display_name | Helicase |
| concepts[2].id | https://openalex.org/C67705224 |
| concepts[2].level | 3 |
| concepts[2].score | 0.7798756957054138 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q11053 |
| concepts[2].display_name | RNA |
| concepts[3].id | https://openalex.org/C10879258 |
| concepts[3].level | 4 |
| concepts[3].score | 0.7371492981910706 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q76826611 |
| concepts[3].display_name | RNase P |
| concepts[4].id | https://openalex.org/C75449159 |
| concepts[4].level | 5 |
| concepts[4].score | 0.7300149202346802 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q418869 |
| concepts[4].display_name | Exosome complex |
| concepts[5].id | https://openalex.org/C68592252 |
| concepts[5].level | 5 |
| concepts[5].score | 0.7202872037887573 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q17913854 |
| concepts[5].display_name | RNA Helicase A |
| concepts[6].id | https://openalex.org/C42369531 |
| concepts[6].level | 5 |
| concepts[6].score | 0.6952551603317261 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q22328565 |
| concepts[6].display_name | Degradosome |
| concepts[7].id | https://openalex.org/C2191507 |
| concepts[7].level | 5 |
| concepts[7].score | 0.5502937436103821 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q7277185 |
| concepts[7].display_name | RNA silencing |
| concepts[8].id | https://openalex.org/C41282012 |
| concepts[8].level | 4 |
| concepts[8].score | 0.5350426435470581 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q3928341 |
| concepts[8].display_name | RNA-binding protein |
| concepts[9].id | https://openalex.org/C95444343 |
| concepts[9].level | 1 |
| concepts[9].score | 0.4921383261680603 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q7141 |
| concepts[9].display_name | Cell biology |
| concepts[10].id | https://openalex.org/C194993378 |
| concepts[10].level | 4 |
| concepts[10].score | 0.4784115254878998 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q427087 |
| concepts[10].display_name | Non-coding RNA |
| concepts[11].id | https://openalex.org/C148625055 |
| concepts[11].level | 5 |
| concepts[11].score | 0.45094797015190125 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q418840 |
| concepts[11].display_name | Riboswitch |
| concepts[12].id | https://openalex.org/C54355233 |
| concepts[12].level | 1 |
| concepts[12].score | 0.427718847990036 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q7162 |
| concepts[12].display_name | Genetics |
| concepts[13].id | https://openalex.org/C104317684 |
| concepts[13].level | 2 |
| concepts[13].score | 0.1756039261817932 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q7187 |
| concepts[13].display_name | Gene |
| concepts[14].id | https://openalex.org/C166703698 |
| concepts[14].level | 4 |
| concepts[14].score | 0.1748879849910736 |
| concepts[14].wikidata | https://www.wikidata.org/wiki/Q201993 |
| concepts[14].display_name | RNA interference |
| keywords[0].id | https://openalex.org/keywords/biology |
| keywords[0].score | 0.8435028791427612 |
| keywords[0].display_name | Biology |
| keywords[1].id | https://openalex.org/keywords/helicase |
| keywords[1].score | 0.7854456901550293 |
| keywords[1].display_name | Helicase |
| keywords[2].id | https://openalex.org/keywords/rna |
| keywords[2].score | 0.7798756957054138 |
| keywords[2].display_name | RNA |
| keywords[3].id | https://openalex.org/keywords/rnase-p |
| keywords[3].score | 0.7371492981910706 |
| keywords[3].display_name | RNase P |
| keywords[4].id | https://openalex.org/keywords/exosome-complex |
| keywords[4].score | 0.7300149202346802 |
| keywords[4].display_name | Exosome complex |
| keywords[5].id | https://openalex.org/keywords/rna-helicase-a |
| keywords[5].score | 0.7202872037887573 |
| keywords[5].display_name | RNA Helicase A |
| keywords[6].id | https://openalex.org/keywords/degradosome |
| keywords[6].score | 0.6952551603317261 |
| keywords[6].display_name | Degradosome |
| keywords[7].id | https://openalex.org/keywords/rna-silencing |
| keywords[7].score | 0.5502937436103821 |
| keywords[7].display_name | RNA silencing |
| keywords[8].id | https://openalex.org/keywords/rna-binding-protein |
| keywords[8].score | 0.5350426435470581 |
| keywords[8].display_name | RNA-binding protein |
| keywords[9].id | https://openalex.org/keywords/cell-biology |
| keywords[9].score | 0.4921383261680603 |
| keywords[9].display_name | Cell biology |
| keywords[10].id | https://openalex.org/keywords/non-coding-rna |
| keywords[10].score | 0.4784115254878998 |
| keywords[10].display_name | Non-coding RNA |
| keywords[11].id | https://openalex.org/keywords/riboswitch |
| keywords[11].score | 0.45094797015190125 |
| keywords[11].display_name | Riboswitch |
| keywords[12].id | https://openalex.org/keywords/genetics |
| keywords[12].score | 0.427718847990036 |
| keywords[12].display_name | Genetics |
| keywords[13].id | https://openalex.org/keywords/gene |
| keywords[13].score | 0.1756039261817932 |
| keywords[13].display_name | Gene |
| keywords[14].id | https://openalex.org/keywords/rna-interference |
| keywords[14].score | 0.1748879849910736 |
| keywords[14].display_name | RNA interference |
| language | en |
| locations[0].id | doi:10.1093/nar/gkae511 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S134668137 |
| locations[0].source.issn | 0305-1048, 1362-4954, 1362-4962 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 0305-1048 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Nucleic Acids Research |
| locations[0].source.host_organization | https://openalex.org/P4310311648 |
| locations[0].source.host_organization_name | Oxford University Press |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310311648, https://openalex.org/P4310311647 |
| locations[0].source.host_organization_lineage_names | Oxford University Press, University of Oxford |
| locations[0].license | other-oa |
| locations[0].pdf_url | https://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gkae511/58234502/gkae511.pdf |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/other-oa |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Nucleic Acids Research |
| locations[0].landing_page_url | https://doi.org/10.1093/nar/gkae511 |
| locations[1].id | pmid:38874491 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Nucleic acids research |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/38874491 |
| locations[2].id | pmh:oai:pubmedcentral.nih.gov:11260450 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S2764455111 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | PubMed Central |
| locations[2].source.host_organization | https://openalex.org/I1299303238 |
| locations[2].source.host_organization_name | National Institutes of Health |
| locations[2].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[2].license | other-oa |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | https://openalex.org/licenses/other-oa |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Nucleic Acids Res |
| locations[2].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/11260450 |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5088178390 |
| authorships[0].author.orcid | |
| authorships[0].author.display_name | Stéphane Hausmann |
| authorships[0].countries | CH |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I114457229 |
| authorships[0].affiliations[0].raw_affiliation_string | Department of Microbiology and Molecular Medicine, CMU, Faculty of Medicine, University of Geneva , Geneva , Switzerland |
| authorships[0].institutions[0].id | https://openalex.org/I114457229 |
| authorships[0].institutions[0].ror | https://ror.org/01swzsf04 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I114457229 |
| authorships[0].institutions[0].country_code | CH |
| authorships[0].institutions[0].display_name | University of Geneva |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Stéphane Hausmann |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Department of Microbiology and Molecular Medicine, CMU, Faculty of Medicine, University of Geneva , Geneva , Switzerland |
| authorships[1].author.id | https://openalex.org/A5013111151 |
| authorships[1].author.orcid | https://orcid.org/0000-0003-0046-1723 |
| authorships[1].author.display_name | Johan Geiser |
| authorships[1].countries | CH |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I114457229 |
| authorships[1].affiliations[0].raw_affiliation_string | Department of Microbiology and Molecular Medicine, CMU, Faculty of Medicine, University of Geneva , Geneva , Switzerland |
| authorships[1].institutions[0].id | https://openalex.org/I114457229 |
| authorships[1].institutions[0].ror | https://ror.org/01swzsf04 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I114457229 |
| authorships[1].institutions[0].country_code | CH |
| authorships[1].institutions[0].display_name | University of Geneva |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Johan Geiser |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Department of Microbiology and Molecular Medicine, CMU, Faculty of Medicine, University of Geneva , Geneva , Switzerland |
| authorships[2].author.id | https://openalex.org/A5006221782 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-1529-9928 |
| authorships[2].author.display_name | George E. Allen |
| authorships[2].countries | CH |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I114457229 |
| authorships[2].affiliations[0].raw_affiliation_string | Department of Microbiology and Molecular Medicine, CMU, Faculty of Medicine, University of Geneva , Geneva , Switzerland |
| authorships[2].institutions[0].id | https://openalex.org/I114457229 |
| authorships[2].institutions[0].ror | https://ror.org/01swzsf04 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I114457229 |
| authorships[2].institutions[0].country_code | CH |
| authorships[2].institutions[0].display_name | University of Geneva |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | George Edward Allen |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Department of Microbiology and Molecular Medicine, CMU, Faculty of Medicine, University of Geneva , Geneva , Switzerland |
| authorships[3].author.id | https://openalex.org/A5093717704 |
| authorships[3].author.orcid | |
| authorships[3].author.display_name | Sandra Amandine Marie Geslain |
| authorships[3].countries | CH |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I114457229 |
| authorships[3].affiliations[0].raw_affiliation_string | Department of Microbiology and Molecular Medicine, CMU, Faculty of Medicine, University of Geneva , Geneva , Switzerland |
| authorships[3].institutions[0].id | https://openalex.org/I114457229 |
| authorships[3].institutions[0].ror | https://ror.org/01swzsf04 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I114457229 |
| authorships[3].institutions[0].country_code | CH |
| authorships[3].institutions[0].display_name | University of Geneva |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Sandra Amandine Marie Geslain |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Department of Microbiology and Molecular Medicine, CMU, Faculty of Medicine, University of Geneva , Geneva , Switzerland |
| authorships[4].author.id | https://openalex.org/A5035393865 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-1948-8339 |
| authorships[4].author.display_name | Martina Valentini |
| authorships[4].countries | CH |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I114457229 |
| authorships[4].affiliations[0].raw_affiliation_string | Department of Microbiology and Molecular Medicine, CMU, Faculty of Medicine, University of Geneva , Geneva , Switzerland |
| authorships[4].institutions[0].id | https://openalex.org/I114457229 |
| authorships[4].institutions[0].ror | https://ror.org/01swzsf04 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I114457229 |
| authorships[4].institutions[0].country_code | CH |
| authorships[4].institutions[0].display_name | University of Geneva |
| authorships[4].author_position | last |
| authorships[4].raw_author_name | Martina Valentini |
| authorships[4].is_corresponding | True |
| authorships[4].raw_affiliation_strings | Department of Microbiology and Molecular Medicine, CMU, Faculty of Medicine, University of Geneva , Geneva , Switzerland |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gkae511/58234502/gkae511.pdf |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Intrinsically disordered regions regulate RhlE RNA helicase functions in bacteria |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-23T05:10:03.516525 |
| primary_topic.id | https://openalex.org/T10521 |
| primary_topic.field.id | https://openalex.org/fields/13 |
| primary_topic.field.display_name | Biochemistry, Genetics and Molecular Biology |
| primary_topic.score | 0.9997000098228455 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/1312 |
| primary_topic.subfield.display_name | Molecular Biology |
| primary_topic.display_name | RNA and protein synthesis mechanisms |
| related_works | https://openalex.org/W4206709194, https://openalex.org/W1499063687, https://openalex.org/W2046901426, https://openalex.org/W2312538053, https://openalex.org/W2169361180, https://openalex.org/W2150086112, https://openalex.org/W2792243882, https://openalex.org/W2043322120, https://openalex.org/W1992180542, https://openalex.org/W1587469048 |
| cited_by_count | 5 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 4 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 1 |
| locations_count | 3 |
| best_oa_location.id | doi:10.1093/nar/gkae511 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S134668137 |
| best_oa_location.source.issn | 0305-1048, 1362-4954, 1362-4962 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 0305-1048 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Nucleic Acids Research |
| best_oa_location.source.host_organization | https://openalex.org/P4310311648 |
| best_oa_location.source.host_organization_name | Oxford University Press |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310311648, https://openalex.org/P4310311647 |
| best_oa_location.source.host_organization_lineage_names | Oxford University Press, University of Oxford |
| best_oa_location.license | other-oa |
| best_oa_location.pdf_url | https://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gkae511/58234502/gkae511.pdf |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/other-oa |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Nucleic Acids Research |
| best_oa_location.landing_page_url | https://doi.org/10.1093/nar/gkae511 |
| primary_location.id | doi:10.1093/nar/gkae511 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S134668137 |
| primary_location.source.issn | 0305-1048, 1362-4954, 1362-4962 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 0305-1048 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Nucleic Acids Research |
| primary_location.source.host_organization | https://openalex.org/P4310311648 |
| primary_location.source.host_organization_name | Oxford University Press |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310311648, https://openalex.org/P4310311647 |
| primary_location.source.host_organization_lineage_names | Oxford University Press, University of Oxford |
| primary_location.license | other-oa |
| primary_location.pdf_url | https://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gkae511/58234502/gkae511.pdf |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/other-oa |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Nucleic Acids Research |
| primary_location.landing_page_url | https://doi.org/10.1093/nar/gkae511 |
| publication_date | 2024-06-03 |
| publication_year | 2024 |
| referenced_works | https://openalex.org/W2141885436, https://openalex.org/W2051848082, https://openalex.org/W2017866593, https://openalex.org/W3104778417, https://openalex.org/W2037978116, https://openalex.org/W2057259693, https://openalex.org/W2072690167, https://openalex.org/W1996690481, https://openalex.org/W2058819725, https://openalex.org/W2106854623, https://openalex.org/W3130500054, https://openalex.org/W3146251726, https://openalex.org/W2114823344, https://openalex.org/W1958819694, https://openalex.org/W2102701612, https://openalex.org/W1975121208, https://openalex.org/W2119693327, https://openalex.org/W2016170088, https://openalex.org/W2139066576, https://openalex.org/W2887994055, https://openalex.org/W2969343565, https://openalex.org/W4308343438, https://openalex.org/W2103123576, https://openalex.org/W2132746753, https://openalex.org/W3175151348, https://openalex.org/W4288741469, https://openalex.org/W2141245000, https://openalex.org/W2115154628, https://openalex.org/W4387729246, https://openalex.org/W2115419697, https://openalex.org/W2117160134, https://openalex.org/W2170551349, https://openalex.org/W2131478115, https://openalex.org/W2179438025, https://openalex.org/W2021567743, https://openalex.org/W2767002967, https://openalex.org/W2119137031, https://openalex.org/W3048271700, https://openalex.org/W2043213657, https://openalex.org/W2167279371, https://openalex.org/W2054246078, https://openalex.org/W2124162379, https://openalex.org/W2590643905, https://openalex.org/W2903238489, https://openalex.org/W3206940651, https://openalex.org/W2794654572, https://openalex.org/W4283704066, https://openalex.org/W3112003419, https://openalex.org/W4214882506, https://openalex.org/W2110035347, https://openalex.org/W3127470297, https://openalex.org/W2106107840, https://openalex.org/W2047670590, https://openalex.org/W2892516888, https://openalex.org/W2016537573, https://openalex.org/W2096365000, https://openalex.org/W1977592786, https://openalex.org/W2134875617, https://openalex.org/W1971166054, https://openalex.org/W2064428315, https://openalex.org/W2078532539, https://openalex.org/W4377819735, https://openalex.org/W4280514348, https://openalex.org/W2884082692, https://openalex.org/W2756821926, https://openalex.org/W3091174223, https://openalex.org/W2951727057, https://openalex.org/W3000736974, https://openalex.org/W1988746124, https://openalex.org/W1583756835, https://openalex.org/W2125772544, https://openalex.org/W2168912093, https://openalex.org/W2171432524, https://openalex.org/W4386195056, https://openalex.org/W2118238803, https://openalex.org/W3177828909, https://openalex.org/W3211795435, https://openalex.org/W2110065044, https://openalex.org/W2804007336 |
| referenced_works_count | 79 |
| abstract_inverted_index.E | 95, 136 |
| abstract_inverted_index.a | 34, 84, 97, 129, 139 |
| abstract_inverted_index.By | 172 |
| abstract_inverted_index.In | 20 |
| abstract_inverted_index.as | 116 |
| abstract_inverted_index.at | 155 |
| abstract_inverted_index.in | 4, 41, 68, 77, 100, 106, 158 |
| abstract_inverted_index.is | 74 |
| abstract_inverted_index.of | 56, 128, 141, 161, 189, 196 |
| abstract_inverted_index.on | 192 |
| abstract_inverted_index.to | 118, 168 |
| abstract_inverted_index.we | 45 |
| abstract_inverted_index.IDR | 49, 73, 190 |
| abstract_inverted_index.REC | 36, 79 |
| abstract_inverted_index.RNA | 1, 5, 31, 53, 61, 81, 146, 170, 197 |
| abstract_inverted_index.The | 122, 148 |
| abstract_inverted_index.and | 16, 29, 63, 90, 137, 144, 181 |
| abstract_inverted_index.are | 110 |
| abstract_inverted_index.but | 39, 113 |
| abstract_inverted_index.for | 87 |
| abstract_inverted_index.how | 47 |
| abstract_inverted_index.its | 164 |
| abstract_inverted_index.low | 156 |
| abstract_inverted_index.our | 184 |
| abstract_inverted_index.the | 21, 26, 48, 93, 159, 187, 193 |
| abstract_inverted_index.Both | 58 |
| abstract_inverted_index.IDRs | 59, 104, 175 |
| abstract_inverted_index.RhlE | 52 |
| abstract_inverted_index.both | 142, 177 |
| abstract_inverted_index.cold | 126 |
| abstract_inverted_index.core | 38, 80, 179 |
| abstract_inverted_index.mRNA | 101 |
| abstract_inverted_index.more | 75 |
| abstract_inverted_index.show | 46 |
| abstract_inverted_index.that | 12, 109, 174 |
| abstract_inverted_index.with | 92, 134, 163 |
| abstract_inverted_index.Here, | 44 |
| abstract_inverted_index.IDRs. | 43 |
| abstract_inverted_index.RNase | 94, 135 |
| abstract_inverted_index.RhlE1 | 28, 143 |
| abstract_inverted_index.RhlE2 | 30, 72, 145 |
| abstract_inverted_index.gains | 132 |
| abstract_inverted_index.phase | 14, 64, 88 |
| abstract_inverted_index.rhlE1 | 130 |
| abstract_inverted_index.share | 33 |
| abstract_inverted_index.study | 185 |
| abstract_inverted_index.their | 119 |
| abstract_inverted_index.(IDRs) | 11 |
| abstract_inverted_index.RhlE1, | 162 |
| abstract_inverted_index.active | 112 |
| abstract_inverted_index.differ | 40 |
| abstract_inverted_index.effect | 166 |
| abstract_inverted_index.enable | 13 |
| abstract_inverted_index.growth | 127, 154 |
| abstract_inverted_index.impact | 188 |
| abstract_inverted_index.linked | 167 |
| abstract_inverted_index.native | 120 |
| abstract_inverted_index.player | 99 |
| abstract_inverted_index.subset | 140 |
| abstract_inverted_index.absence | 160 |
| abstract_inverted_index.affects | 138 |
| abstract_inverted_index.binding | 62 |
| abstract_inverted_index.chimera | 124, 150 |
| abstract_inverted_index.complex | 17 |
| abstract_inverted_index.crucial | 98 |
| abstract_inverted_index.defines | 51, 186 |
| abstract_inverted_index.enzymes | 3 |
| abstract_inverted_index.feature | 7 |
| abstract_inverted_index.greater | 85 |
| abstract_inverted_index.hampers | 152 |
| abstract_inverted_index.instead | 151 |
| abstract_inverted_index.mutant, | 131 |
| abstract_inverted_index.protein | 178 |
| abstract_inverted_index.regions | 10 |
| abstract_inverted_index.results | 105 |
| abstract_inverted_index.showing | 173 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.However, | 71 |
| abstract_inverted_index.Swapping | 103 |
| abstract_inverted_index.aberrant | 169 |
| abstract_inverted_index.chimeric | 107 |
| abstract_inverted_index.compared | 117 |
| abstract_inverted_index.distinct | 115 |
| abstract_inverted_index.exhibits | 83 |
| abstract_inverted_index.helicase | 54 |
| abstract_inverted_index.improves | 125 |
| abstract_inverted_index.modulate | 176 |
| abstract_inverted_index.pathogen | 23 |
| abstract_inverted_index.proteins | 67, 108 |
| abstract_inverted_index.targets. | 147 |
| abstract_inverted_index.tendency | 86 |
| abstract_inverted_index.bacterial | 22, 153 |
| abstract_inverted_index.catalytic | 37 |
| abstract_inverted_index.clusters. | 70 |
| abstract_inverted_index.conserved | 35 |
| abstract_inverted_index.diversity | 50, 191 |
| abstract_inverted_index.droplets. | 171 |
| abstract_inverted_index.efficient | 76 |
| abstract_inverted_index.enhancing | 78 |
| abstract_inverted_index.function. | 57 |
| abstract_inverted_index.helicases | 32 |
| abstract_inverted_index.interacts | 91 |
| abstract_inverted_index.molecular | 18 |
| abstract_inverted_index.C-terminal | 42 |
| abstract_inverted_index.activities | 180 |
| abstract_inverted_index.disordered | 9 |
| abstract_inverted_index.facilitate | 60 |
| abstract_inverted_index.functional | 194 |
| abstract_inverted_index.helicases. | 198 |
| abstract_inverted_index.localizing | 66 |
| abstract_inverted_index.separation | 15 |
| abstract_inverted_index.unwinding, | 82 |
| abstract_inverted_index.Pseudomonas | 24 |
| abstract_inverted_index.aeruginosa, | 25 |
| abstract_inverted_index.cytoplasmic | 69 |
| abstract_inverted_index.detrimental | 165 |
| abstract_inverted_index.interaction | 133 |
| abstract_inverted_index.separation, | 65, 89 |
| abstract_inverted_index.specificity | 55 |
| abstract_inverted_index.subcellular | 182 |
| abstract_inverted_index.degradation. | 102 |
| abstract_inverted_index.functionally | 114 |
| abstract_inverted_index.temperatures | 157 |
| abstract_inverted_index.biochemically | 111 |
| abstract_inverted_index.counterparts. | 121 |
| abstract_inverted_index.endonuclease, | 96 |
| abstract_inverted_index.interactions. | 19 |
| abstract_inverted_index.intrinsically | 8 |
| abstract_inverted_index.localization, | 183 |
| abstract_inverted_index.non-redundant | 27 |
| abstract_inverted_index.differentiation | 195 |
| abstract_inverted_index.RECRhlE1-IDRRhlE2 | 123 |
| abstract_inverted_index.RECRhlE2-IDRRhlE1 | 149 |
| abstract_inverted_index.metabolism—often | 6 |
| abstract_inverted_index.helicases—central | 2 |
| cited_by_percentile_year.max | 98 |
| cited_by_percentile_year.min | 90 |
| corresponding_author_ids | https://openalex.org/A5035393865 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 5 |
| corresponding_institution_ids | https://openalex.org/I114457229 |
| citation_normalized_percentile.value | 0.8287151 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |