Investigation of possible relationship between atopic dermatitis and salivary biomarkers, stress, and sleep disorders Article Swipe
Juliany Lima Estefan
,
Dennis de Carvalho Ferreira
,
Fernanda Sampaio Cavalcante
,
Kátia Regina Netto dos Santos
,
Márcia Gonçalves Ribeiro
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.12998/wjcc.v11.i17.3958
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.12998/wjcc.v11.i17.3958
Atopic dermatitis (AD) is a chronic, relapsing, multifactorial inflammatory disease with genetic, environmental, and immunological characteristics. The quality of life and sleep of patients and their families are affected by AD, which triggers stress, described as one of the factors that worsens AD. Salivary biomarkers such as cortisol, alpha-amylase, chromogranin A, and melatonin have been associated with stress and sleep disturbances. Therefore, the evaluation of stress and sleep disorders using salivary biomarkers in AD patients is important. This review aims to describe the possible relationship between atopic dermatitis and stress, sleep disorders, and salivary biomarkers, seeking to contribute to better understanding and clinical management of AD. This descriptive study is characterized as a narrative literature review. A literature search was conducted of studies published in English and Portuguese between January 2012 and October 2022 that are available in electronic media from various databases, such as Scientific Electronic Library Online, Latin American and Caribbean Literature on Health Sciences, and PubMed. AD is associated with different degrees of impact on the lives of individuals who present with the disease. Psychological stress may induce changes in saliva composition and worsen AD; at the same time, the severity of the disease may be associated with emotional impact. Further studies are needed to assess and correlate AD severity, stress, and sleep disturbances with salivary biomarkers in order to better understand this association.
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.12998/wjcc.v11.i17.3958
- OA Status
- diamond
- Cited By
- 6
- References
- 51
- Related Works
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- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4380264937Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.12998/wjcc.v11.i17.3958Digital Object Identifier
- Title
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Investigation of possible relationship between atopic dermatitis and salivary biomarkers, stress, and sleep disordersWork title
- Type
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reviewOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
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2023-06-12Full publication date if available
- Authors
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Juliany Lima Estefan, Dennis de Carvalho Ferreira, Fernanda Sampaio Cavalcante, Kátia Regina Netto dos Santos, Márcia Gonçalves RibeiroList of authors in order
- Landing page
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https://doi.org/10.12998/wjcc.v11.i17.3958Publisher landing page
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YesWhether a free full text is available
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diamondOpen access status per OpenAlex
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https://doi.org/10.12998/wjcc.v11.i17.3958Direct OA link when available
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Medicine, Atopic dermatitis, Disease, Saliva, Clinical psychology, Internal medicine, DermatologyTop concepts (fields/topics) attached by OpenAlex
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6Total citation count in OpenAlex
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2025: 2, 2024: 4Per-year citation counts (last 5 years)
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51Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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