Ketamina y dexmedetomidina en anestesia general: una revisión sistemática Article Swipe
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· 2025
· Open Access
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· DOI: https://doi.org/10.25237/revchilanestv54n6-04
Introduction: The combination of dexmedetomidine and ketamine, known as “ketodex,” has emerged as a promising alternative for general anesthesia and sedation. This approach enhances the analgesic and anesthetic effects of both drugs, reducing their individual adverse effects. Methodology: This was a systematic review of studies on the use of ketodex in general anesthesia. Results: Seventeen relevant studies were identified, which included a variety of surgeries. These studies compared traditional anesthesia versus opioid-free anesthesia, highlighting variability in dosage and administration techniques. The combined use of dexmedetomidine and ketamine in general anesthesia is associated with reduced pain, reduced need for opioids, and decreased postoperative nausea and vomiting. The limited evidence and variability highlight the need for further research about the benefits and risks of ketodex in adults. Conclusion: The combined use of dexmedetomidine and ketamine in general anesthesia is associated with reduced pain, reduced need for opioids, and decreased postoperative nausea and vomiting. However, further studies are required to firmly support its use.
Related Topics
- Type
- article
- Landing Page
- https://doi.org/10.25237/revchilanestv54n6-04
- OA Status
- diamond
- References
- 25
- OpenAlex ID
- https://openalex.org/W7106681798
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W7106681798Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.25237/revchilanestv54n6-04Digital Object Identifier
- Title
-
Ketamina y dexmedetomidina en anestesia general: una revisión sistemáticaWork title
- Type
-
articleOpenAlex work type
- Publication year
-
2025Year of publication
- Publication date
-
2025-11-26Full publication date if available
- Authors
-
Elsy Sofía CalleList of authors in order
- Landing page
-
https://doi.org/10.25237/revchilanestv54n6-04Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
diamondOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.25237/revchilanestv54n6-04Direct OA link when available
- Concepts
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Dexmedetomidine, Ketamine, Medicine, Anesthesia, Anesthetic, Nausea, Analgesic, Adverse effect, Sedation, Anesthetic Agent, Postoperative nausea and vomiting, Intensive care medicine, Anesthetic EffectTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
- References (count)
-
25Number of works referenced by this work
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