Exploring foci of:
Frontiers in Immunology • Vol 13
KIR in Allogeneic Hematopoietic Stem Cell Transplantation: Need for a Unified Paradigm for Donor Selection
February 2022 • Adèle Dhuyser, Alice Aarnink, Michaël Pérès, Jyothi Jayaraman, Neda Nemat‐Gorgani, Marie-Thérèse Rubio, John Trowsdale, James A. Traherne
Allogeneic hematopoietic stem cell transplantation (aHSCT) is a lifesaving therapy for hematological malignancies. For years, a fully matched HLA donor was a requisite for the procedure. However, new immunosuppressive strategies have enabled the recruitment of viable alternative donors, particularly haploidentical donors. Over 95% of patients have at least two potential haploidentical donors available to them. To identify the best haploidentical donor, the assessment of new immunogenetic criteria could help. To th…
Hematopoietic Stem Cell Transplantation
Medicine
Immunology
Stem Cell
Bioinformatics
Computer Science
Biology
Machine Learning
Internal Medicine
Paleontology