Lab-in-the-loop machine learning for brain-targeting delivery system design Article Swipe

PDF

Qiujun Qiu , Shiyi Li , Jixian Zhang , Jixiang Chen , Xinyi Ding , Shengyao Liu , Jianyong Sheng , Zhiqing Pang , Ru Zhang , Anni Wang , Meichen Dong , Meng Zhang , Miaomiao Zhang , Tun Lu , Ning Gu , Shuigeng Zhou , Defang Ouyang , Libing Jiang , Shuangjia Zheng , Jianxin Wang ·

YOU? · · 2025 · Open Access · · DOI: https://doi.org/10.1016/j.celbio.2025.100130

Related Topics

Computer Science

Artificial Intelligence

Engineering

Combinatorics

Mathematics

Concepts

Loop (graph theory) Computer science Artificial intelligence Engineering Combinatorics Mathematics

Metadata

Type: article
Language: en
Landing Page: https://doi.org/10.1016/j.celbio.2025.100130
PDF: https://www.cell.com/cell-biomaterials/pdf/S3050-5623(25)00121-7.pdf
OA Status: hybrid
Cited By: 2
References: 38
Related Works: 10
OpenAlex ID: https://openalex.org/W4411923951

All OpenAlex metadata

Raw OpenAlex JSON

OpenAlex ID: https://openalex.org/W4411923951

Canonical identifier for this work in OpenAlex
DOI: https://doi.org/10.1016/j.celbio.2025.100130

Digital Object Identifier
Title: Lab-in-the-loop machine learning for brain-targeting delivery system design

Work title
Type: article

OpenAlex work type
Language: en

Primary language
Publication year: 2025

Year of publication
Publication date: 2025-07-02

Full publication date if available
Authors: Qiujun Qiu, Shiyi Li, Jixian Zhang, Jixiang Chen, Xinyi Ding, Shengyao Liu, Jianyong Sheng, Zhiqing Pang, Ru Zhang, Anni Wang, Meichen Dong, Meng Zhang, Miaomiao Zhang, Tun Lu, Ning Gu, Shuigeng Zhou, Defang Ouyang, Libing Jiang, Shuangjia Zheng, Jianxin Wang

List of authors in order
Landing page: https://doi.org/10.1016/j.celbio.2025.100130

Publisher landing page
PDF URL: https://www.cell.com/cell-biomaterials/pdf/S3050-5623(25)00121-7.pdf

Direct link to full text PDF
Open access: Yes

Whether a free full text is available
OA status: hybrid

Open access status per OpenAlex
OA URL: https://www.cell.com/cell-biomaterials/pdf/S3050-5623(25)00121-7.pdf

Direct OA link when available
Concepts: Loop (graph theory), Computer science, Artificial intelligence, Engineering, Combinatorics, Mathematics

Top concepts (fields/topics) attached by OpenAlex
Cited by: 2

Total citation count in OpenAlex
Citations by year (recent): 2025: 2

Per-year citation counts (last 5 years)
References (count): 38

Number of works referenced by this work
Related works (count): 10

Other works algorithmically related by OpenAlex

Full payload

id	https://openalex.org/W4411923951
doi	https://doi.org/10.1016/j.celbio.2025.100130
ids.doi	https://doi.org/10.1016/j.celbio.2025.100130
ids.openalex	https://openalex.org/W4411923951
fwci	5.88452018
type	article
title	Lab-in-the-loop machine learning for brain-targeting delivery system design
biblio.issue	9
biblio.volume	1
biblio.last_page	100130
biblio.first_page	100130
topics[0].id	https://openalex.org/T11601
topics[0].field.id	https://openalex.org/fields/28
topics[0].field.display_name	Neuroscience
topics[0].score	0.9970999956130981
topics[0].domain.id	https://openalex.org/domains/1
topics[0].domain.display_name	Life Sciences
topics[0].subfield.id	https://openalex.org/subfields/2804
topics[0].subfield.display_name	Cellular and Molecular Neuroscience
topics[0].display_name	Neuroscience and Neural Engineering
topics[1].id	https://openalex.org/T11472
topics[1].field.id	https://openalex.org/fields/15
topics[1].field.display_name	Chemical Engineering
topics[1].score	0.9914000034332275
topics[1].domain.id	https://openalex.org/domains/3
topics[1].domain.display_name	Physical Sciences
topics[1].subfield.id	https://openalex.org/subfields/1502
topics[1].subfield.display_name	Bioengineering
topics[1].display_name	Analytical Chemistry and Sensors
topics[2].id	https://openalex.org/T11778
topics[2].field.id	https://openalex.org/fields/22
topics[2].field.display_name	Engineering
topics[2].score	0.9914000034332275
topics[2].domain.id	https://openalex.org/domains/3
topics[2].domain.display_name	Physical Sciences
topics[2].subfield.id	https://openalex.org/subfields/2208
topics[2].subfield.display_name	Electrical and Electronic Engineering
topics[2].display_name	Electrical and Bioimpedance Tomography
is_xpac	False
apc_list
apc_paid
concepts[0].id	https://openalex.org/C184670325
concepts[0].level	2
concepts[0].score	0.4996459484100342
concepts[0].wikidata	https://www.wikidata.org/wiki/Q512604
concepts[0].display_name	Loop (graph theory)
concepts[1].id	https://openalex.org/C41008148
concepts[1].level	0
concepts[1].score	0.4980647563934326
concepts[1].wikidata	https://www.wikidata.org/wiki/Q21198
concepts[1].display_name	Computer science
concepts[2].id	https://openalex.org/C154945302
concepts[2].level	1
concepts[2].score	0.32320505380630493
concepts[2].wikidata	https://www.wikidata.org/wiki/Q11660
concepts[2].display_name	Artificial intelligence
concepts[3].id	https://openalex.org/C127413603
concepts[3].level	0
concepts[3].score	0.3222864270210266
concepts[3].wikidata	https://www.wikidata.org/wiki/Q11023
concepts[3].display_name	Engineering
concepts[4].id	https://openalex.org/C114614502
concepts[4].level	1
concepts[4].score	0.0
concepts[4].wikidata	https://www.wikidata.org/wiki/Q76592
concepts[4].display_name	Combinatorics
concepts[5].id	https://openalex.org/C33923547
concepts[5].level	0
concepts[5].score	0.0
concepts[5].wikidata	https://www.wikidata.org/wiki/Q395
concepts[5].display_name	Mathematics
keywords[0].id	https://openalex.org/keywords/loop
keywords[0].score	0.4996459484100342
keywords[0].display_name	Loop (graph theory)
keywords[1].id	https://openalex.org/keywords/computer-science
keywords[1].score	0.4980647563934326
keywords[1].display_name	Computer science
keywords[2].id	https://openalex.org/keywords/artificial-intelligence
keywords[2].score	0.32320505380630493
keywords[2].display_name	Artificial intelligence
keywords[3].id	https://openalex.org/keywords/engineering
keywords[3].score	0.3222864270210266
keywords[3].display_name	Engineering
language	en
locations[0].id	doi:10.1016/j.celbio.2025.100130
locations[0].is_oa	True
locations[0].source.id	https://openalex.org/S5407047401
locations[0].source.issn	3050-5623
locations[0].source.type	journal
locations[0].source.is_oa	False
locations[0].source.issn_l	3050-5623
locations[0].source.is_core	False
locations[0].source.is_in_doaj	False
locations[0].source.display_name	Cell Biomaterials
locations[0].source.host_organization
locations[0].source.host_organization_name
locations[0].license	cc-by-nc
locations[0].pdf_url	https://www.cell.com/cell-biomaterials/pdf/S3050-5623(25)00121-7.pdf
locations[0].version	publishedVersion
locations[0].raw_type	journal-article
locations[0].license_id	https://openalex.org/licenses/cc-by-nc
locations[0].is_accepted	True
locations[0].is_published	True
locations[0].raw_source_name	Cell Biomaterials
locations[0].landing_page_url	https://doi.org/10.1016/j.celbio.2025.100130
indexed_in	crossref
authorships[0].author.id	https://openalex.org/A5003068382
authorships[0].author.orcid	https://orcid.org/0000-0003-2420-9864
authorships[0].author.display_name	Qiujun Qiu
authorships[0].author_position	first
authorships[0].raw_author_name	Qiujun Qiu
authorships[0].is_corresponding	False
authorships[1].author.id	https://openalex.org/A5100626062
authorships[1].author.orcid	https://orcid.org/0000-0002-1650-3249
authorships[1].author.display_name	Shiyi Li
authorships[1].author_position	middle
authorships[1].raw_author_name	Shiyi Li
authorships[1].is_corresponding	False
authorships[2].author.id	https://openalex.org/A5101555558
authorships[2].author.orcid	https://orcid.org/0000-0003-0830-0369
authorships[2].author.display_name	Jixian Zhang
authorships[2].author_position	middle
authorships[2].raw_author_name	Jixian Zhang
authorships[2].is_corresponding	False
authorships[3].author.id	https://openalex.org/A5100666973
authorships[3].author.orcid	https://orcid.org/0000-0002-6726-9878
authorships[3].author.display_name	Jixiang Chen
authorships[3].author_position	middle
authorships[3].raw_author_name	Jixiang Chen
authorships[3].is_corresponding	False
authorships[4].author.id	https://openalex.org/A5101702431
authorships[4].author.orcid	https://orcid.org/0000-0002-0867-788X
authorships[4].author.display_name	Xinyi Ding
authorships[4].author_position	middle
authorships[4].raw_author_name	Xinyi Ding
authorships[4].is_corresponding	False
authorships[5].author.id	https://openalex.org/A5086505734
authorships[5].author.orcid	https://orcid.org/0009-0007-4076-7491
authorships[5].author.display_name	Shengyao Liu
authorships[5].author_position	middle
authorships[5].raw_author_name	Shengyao Liu
authorships[5].is_corresponding	False
authorships[6].author.id	https://openalex.org/A5059970361
authorships[6].author.orcid	https://orcid.org/0000-0003-2363-1609
authorships[6].author.display_name	Jianyong Sheng
authorships[6].author_position	middle
authorships[6].raw_author_name	Jianyong Sheng
authorships[6].is_corresponding	False
authorships[7].author.id	https://openalex.org/A5106940959
authorships[7].author.orcid	https://orcid.org/0000-0003-0228-904X
authorships[7].author.display_name	Zhiqing Pang
authorships[7].author_position	middle
authorships[7].raw_author_name	Zhiqing Pang
authorships[7].is_corresponding	False
authorships[8].author.id	https://openalex.org/A5101790472
authorships[8].author.orcid	https://orcid.org/0009-0009-3569-2848
authorships[8].author.display_name	Ru Zhang
authorships[8].author_position	middle
authorships[8].raw_author_name	Ru Zhang
authorships[8].is_corresponding	False
authorships[9].author.id	https://openalex.org/A5086865014
authorships[9].author.orcid	https://orcid.org/0000-0003-3109-7514
authorships[9].author.display_name	Anni Wang
authorships[9].author_position	middle
authorships[9].raw_author_name	Anni Wang
authorships[9].is_corresponding	False
authorships[10].author.id	https://openalex.org/A5080604666
authorships[10].author.orcid	https://orcid.org/0000-0001-9437-9290
authorships[10].author.display_name	Meichen Dong
authorships[10].author_position	middle
authorships[10].raw_author_name	Meichen Dong
authorships[10].is_corresponding	False
authorships[11].author.id	https://openalex.org/A5100437809
authorships[11].author.orcid	https://orcid.org/0000-0003-2188-8195
authorships[11].author.display_name	Meng Zhang
authorships[11].author_position	middle
authorships[11].raw_author_name	Meng Zhang
authorships[11].is_corresponding	False
authorships[12].author.id	https://openalex.org/A5100357912
authorships[12].author.orcid	https://orcid.org/0000-0003-0457-3335
authorships[12].author.display_name	Miaomiao Zhang
authorships[12].author_position	middle
authorships[12].raw_author_name	Miaomiao Zhang
authorships[12].is_corresponding	False
authorships[13].author.id	https://openalex.org/A5052986785
authorships[13].author.orcid
authorships[13].author.display_name	Tun Lu
authorships[13].author_position	middle
authorships[13].raw_author_name	Tun Lu
authorships[13].is_corresponding	False
authorships[14].author.id	https://openalex.org/A5012421463
authorships[14].author.orcid	https://orcid.org/0000-0003-0047-337X
authorships[14].author.display_name	Ning Gu
authorships[14].author_position	middle
authorships[14].raw_author_name	Ning Gu
authorships[14].is_corresponding	False
authorships[15].author.id	https://openalex.org/A5017862559
authorships[15].author.orcid	https://orcid.org/0000-0002-1949-2768
authorships[15].author.display_name	Shuigeng Zhou
authorships[15].author_position	middle
authorships[15].raw_author_name	Shuigeng Zhou
authorships[15].is_corresponding	False
authorships[16].author.id	https://openalex.org/A5024615233
authorships[16].author.orcid	https://orcid.org/0000-0002-8052-4773
authorships[16].author.display_name	Defang Ouyang
authorships[16].author_position	middle
authorships[16].raw_author_name	Defang Ouyang
authorships[16].is_corresponding	False
authorships[17].author.id	https://openalex.org/A5091064916
authorships[17].author.orcid	https://orcid.org/0000-0002-6185-3432
authorships[17].author.display_name	Libing Jiang
authorships[17].author_position	middle
authorships[17].raw_author_name	Dongsheng Li
authorships[17].is_corresponding	False
authorships[18].author.id	https://openalex.org/A5075817762
authorships[18].author.orcid	https://orcid.org/0000-0001-9747-4285
authorships[18].author.display_name	Shuangjia Zheng
authorships[18].author_position	middle
authorships[18].raw_author_name	Shuangjia Zheng
authorships[18].is_corresponding	False
authorships[19].author.id	https://openalex.org/A5100438345
authorships[19].author.orcid	https://orcid.org/0000-0001-8621-543X
authorships[19].author.display_name	Jianxin Wang
authorships[19].author_position	last
authorships[19].raw_author_name	Jianxin Wang
authorships[19].is_corresponding	False
has_content.pdf	True
has_content.grobid_xml	False
is_paratext	False
open_access.is_oa	True
open_access.oa_url	https://www.cell.com/cell-biomaterials/pdf/S3050-5623(25)00121-7.pdf
open_access.oa_status	hybrid
open_access.any_repository_has_fulltext	False
created_date	2025-10-10T00:00:00
display_name	Lab-in-the-loop machine learning for brain-targeting delivery system design
has_fulltext	False
is_retracted	False
updated_date	2025-11-06T03:46:38.306776
primary_topic.id	https://openalex.org/T11601
primary_topic.field.id	https://openalex.org/fields/28
primary_topic.field.display_name	Neuroscience
primary_topic.score	0.9970999956130981
primary_topic.domain.id	https://openalex.org/domains/1
primary_topic.domain.display_name	Life Sciences
primary_topic.subfield.id	https://openalex.org/subfields/2804
primary_topic.subfield.display_name	Cellular and Molecular Neuroscience
primary_topic.display_name	Neuroscience and Neural Engineering
related_works	https://openalex.org/W4391375266, https://openalex.org/W2899084033, https://openalex.org/W2748952813, https://openalex.org/W24774503, https://openalex.org/W2390279801, https://openalex.org/W4391913857, https://openalex.org/W2358668433, https://openalex.org/W4396701345, https://openalex.org/W2376932109, https://openalex.org/W2001405890
cited_by_count	2
counts_by_year[0].year	2025
counts_by_year[0].cited_by_count	2
locations_count	1
best_oa_location.id	doi:10.1016/j.celbio.2025.100130
best_oa_location.is_oa	True
best_oa_location.source.id	https://openalex.org/S5407047401
best_oa_location.source.issn	3050-5623
best_oa_location.source.type	journal
best_oa_location.source.is_oa	False
best_oa_location.source.issn_l	3050-5623
best_oa_location.source.is_core	False
best_oa_location.source.is_in_doaj	False
best_oa_location.source.display_name	Cell Biomaterials
best_oa_location.source.host_organization
best_oa_location.source.host_organization_name
best_oa_location.license	cc-by-nc
best_oa_location.pdf_url	https://www.cell.com/cell-biomaterials/pdf/S3050-5623(25)00121-7.pdf
best_oa_location.version	publishedVersion
best_oa_location.raw_type	journal-article
best_oa_location.license_id	https://openalex.org/licenses/cc-by-nc
best_oa_location.is_accepted	True
best_oa_location.is_published	True
best_oa_location.raw_source_name	Cell Biomaterials
best_oa_location.landing_page_url	https://doi.org/10.1016/j.celbio.2025.100130
primary_location.id	doi:10.1016/j.celbio.2025.100130
primary_location.is_oa	True
primary_location.source.id	https://openalex.org/S5407047401
primary_location.source.issn	3050-5623
primary_location.source.type	journal
primary_location.source.is_oa	False
primary_location.source.issn_l	3050-5623
primary_location.source.is_core	False
primary_location.source.is_in_doaj	False
primary_location.source.display_name	Cell Biomaterials
primary_location.source.host_organization
primary_location.source.host_organization_name
primary_location.license	cc-by-nc
primary_location.pdf_url	https://www.cell.com/cell-biomaterials/pdf/S3050-5623(25)00121-7.pdf
primary_location.version	publishedVersion
primary_location.raw_type	journal-article
primary_location.license_id	https://openalex.org/licenses/cc-by-nc
primary_location.is_accepted	True
primary_location.is_published	True
primary_location.raw_source_name	Cell Biomaterials
primary_location.landing_page_url	https://doi.org/10.1016/j.celbio.2025.100130
publication_date	2025-07-02
publication_year	2025
referenced_works	https://openalex.org/W2253028130, https://openalex.org/W3134309694, https://openalex.org/W2091880370, https://openalex.org/W3127021983, https://openalex.org/W4377011282, https://openalex.org/W6753037684, https://openalex.org/W2796781998, https://openalex.org/W6662835432, https://openalex.org/W2297044638, https://openalex.org/W2063370961, https://openalex.org/W3083698728, https://openalex.org/W2344644350, https://openalex.org/W3006987776, https://openalex.org/W4221081366, https://openalex.org/W3164483271, https://openalex.org/W2953089157, https://openalex.org/W3216736322, https://openalex.org/W4396929336, https://openalex.org/W4389428623, https://openalex.org/W4400266986, https://openalex.org/W2395300225, https://openalex.org/W7075593541, https://openalex.org/W2152366705, https://openalex.org/W2063318887, https://openalex.org/W2059999322, https://openalex.org/W4388290259, https://openalex.org/W2040042243, https://openalex.org/W2006237391, https://openalex.org/W2935857979, https://openalex.org/W2554773181, https://openalex.org/W4385268888, https://openalex.org/W152943885, https://openalex.org/W3177350416, https://openalex.org/W3004305206, https://openalex.org/W4226061388, https://openalex.org/W2050271125, https://openalex.org/W2013262011, https://openalex.org/W2884383626
referenced_works_count	38
abstract_inverted_index
cited_by_percentile_year.max	97
cited_by_percentile_year.min	95
countries_distinct_count	0
institutions_distinct_count	20
citation_normalized_percentile.value	0.91447482
citation_normalized_percentile.is_in_top_1_percent	False
citation_normalized_percentile.is_in_top_10_percent	True