Lactate to Albumin Ratio for Predicting Clinical Outcomes after In-Hospital Cardiac Arrest Article Swipe
Jafer Haschemi
,
Charlotte Theresia Müller
,
Jean Marc Haurand
,
Daniel Oehler
,
Maximilian Spieker
,
Amin Polzin
,
Malte Kelm
,
Patrick Horn
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.3390/jcm12124136
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.3390/jcm12124136
In-hospital cardiac arrest (IHCA) is associated with high mortality and poor neurological outcomes. Our objective was to assess whether the lactate-to-albumin ratio (LAR) can predict the outcomes in patients after IHCA. We retrospectively screened 75,987 hospitalised patients at a university hospital between 2015 and 2019. The primary endpoint was survival at 30-days. Neurological outcomes were assessed at 30 days using the cerebral performance category scale. 244 patients with IHCA and return of spontaneous circulation (ROSC) were included in this study and divided into quartiles of LAR. Overall, there were no differences in key baseline characteristics or rates of pre-existing comorbidities among the LAR quartiles. Patients with higher LAR had poorer survival after IHCA compared to patients with lower LAR: Q1, 70.4% of the patients; Q2, 50.8% of the patients; Q3, 26.2% of the patients; Q4, 6.6% of the patients (p = 0.001). Across increasing quartiles, the probability of a favourable neurological outcome in patients with ROSC after IHCA decreased: Q1: 49.2% of the patients; Q2: 32.8% of the patients; Q3: 14.7% of the patients; Q4: 3.2% of the patients (p = 0.001). The AUCs for predicting 30-days survival using the LAR were higher as compared to using a single measurement of lactate or albumin. The prognostic performance of LAR was superior to that of a single measurement of lactate or albumin for predicting survival after IHCA.
Related Topics
Concepts
Medicine
Quartile
Internal medicine
Albumin
Return of spontaneous circulation
Cardiology
Confidence interval
Surgery
Cardiopulmonary resuscitation
Resuscitation
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/jcm12124136
- https://www.mdpi.com/2077-0383/12/12/4136/pdf?version=1687175870
- OA Status
- gold
- Cited By
- 12
- References
- 58
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4381432524
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4381432524Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3390/jcm12124136Digital Object Identifier
- Title
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Lactate to Albumin Ratio for Predicting Clinical Outcomes after In-Hospital Cardiac ArrestWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
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2023-06-19Full publication date if available
- Authors
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Jafer Haschemi, Charlotte Theresia Müller, Jean Marc Haurand, Daniel Oehler, Maximilian Spieker, Amin Polzin, Malte Kelm, Patrick HornList of authors in order
- Landing page
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https://doi.org/10.3390/jcm12124136Publisher landing page
- PDF URL
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https://www.mdpi.com/2077-0383/12/12/4136/pdf?version=1687175870Direct link to full text PDF
- Open access
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://www.mdpi.com/2077-0383/12/12/4136/pdf?version=1687175870Direct OA link when available
- Concepts
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Medicine, Quartile, Internal medicine, Albumin, Return of spontaneous circulation, Cardiology, Confidence interval, Surgery, Cardiopulmonary resuscitation, ResuscitationTop concepts (fields/topics) attached by OpenAlex
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12Total citation count in OpenAlex
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2025: 4, 2024: 8Per-year citation counts (last 5 years)
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58Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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