lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements Article Swipe
M. Grace Gordon
,
Fumitaka Inoue
,
Beth Martin
,
Max Schubach
,
Vikram Agarwal
,
Sean Whalen
,
Shiyun Feng
,
Jingjing Zhao
,
Tal Ashuach
,
Ryan Ziffra
,
Anat Kreimer
,
Ilias Georgakopoulos‐Soares
,
Nir Yosef
,
Chun Ye
,
Katherine S. Pollard
,
Jay Shendure
,
Martin Kircher
,
Nadav Ahituv
·
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1038/s41596-020-0333-5
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1038/s41596-020-0333-5
Related Topics
Concepts
Barcode
Computational biology
Biology
Reporter gene
DNA sequencing
Gene
Regulatory sequence
Functional genomics
Genetics
Genome
Genomics
Regulation of gene expression
Computer science
Gene expression
Operating system
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1038/s41596-020-0333-5
- OA Status
- green
- Cited By
- 139
- References
- 26
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3041677475
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W3041677475Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1038/s41596-020-0333-5Digital Object Identifier
- Title
-
lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elementsWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2020Year of publication
- Publication date
-
2020-07-08Full publication date if available
- Authors
-
M. Grace Gordon, Fumitaka Inoue, Beth Martin, Max Schubach, Vikram Agarwal, Sean Whalen, Shiyun Feng, Jingjing Zhao, Tal Ashuach, Ryan Ziffra, Anat Kreimer, Ilias Georgakopoulos‐Soares, Nir Yosef, Chun Ye, Katherine S. Pollard, Jay Shendure, Martin Kircher, Nadav AhituvList of authors in order
- Landing page
-
https://doi.org/10.1038/s41596-020-0333-5Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- OA URL
-
https://www.ncbi.nlm.nih.gov/pmc/articles/7550205Direct OA link when available
- Concepts
-
Barcode, Computational biology, Biology, Reporter gene, DNA sequencing, Gene, Regulatory sequence, Functional genomics, Genetics, Genome, Genomics, Regulation of gene expression, Computer science, Gene expression, Operating systemTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
139Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 48, 2024: 31, 2023: 26, 2022: 17, 2021: 11Per-year citation counts (last 5 years)
- References (count)
-
26Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W3041677475 |
|---|---|
| doi | https://doi.org/10.1038/s41596-020-0333-5 |
| ids.doi | https://doi.org/10.1038/s41596-020-0333-5 |
| ids.mag | 3041677475 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/32641802 |
| ids.openalex | https://openalex.org/W3041677475 |
| fwci | 5.85161839 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D001483 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Base Sequence |
| mesh[1].qualifier_ui | Q000235 |
| mesh[1].descriptor_ui | D016086 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | genetics |
| mesh[1].descriptor_name | Lentivirus |
| mesh[2].qualifier_ui | Q000235 |
| mesh[2].descriptor_ui | D012045 |
| mesh[2].is_major_topic | False |
| mesh[2].qualifier_name | genetics |
| mesh[2].descriptor_name | Regulatory Sequences, Nucleic Acid |
| mesh[3].qualifier_ui | Q000379 |
| mesh[3].descriptor_ui | D017422 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | methods |
| mesh[3].descriptor_name | Sequence Analysis, DNA |
| mesh[4].qualifier_ui | |
| mesh[4].descriptor_ui | D057188 |
| mesh[4].is_major_topic | True |
| mesh[4].qualifier_name | |
| mesh[4].descriptor_name | Workflow |
| mesh[5].qualifier_ui | |
| mesh[5].descriptor_ui | D001483 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | |
| mesh[5].descriptor_name | Base Sequence |
| mesh[6].qualifier_ui | Q000235 |
| mesh[6].descriptor_ui | D016086 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | genetics |
| mesh[6].descriptor_name | Lentivirus |
| mesh[7].qualifier_ui | Q000235 |
| mesh[7].descriptor_ui | D012045 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | genetics |
| mesh[7].descriptor_name | Regulatory Sequences, Nucleic Acid |
| mesh[8].qualifier_ui | Q000379 |
| mesh[8].descriptor_ui | D017422 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | methods |
| mesh[8].descriptor_name | Sequence Analysis, DNA |
| mesh[9].qualifier_ui | |
| mesh[9].descriptor_ui | D057188 |
| mesh[9].is_major_topic | True |
| mesh[9].qualifier_name | |
| mesh[9].descriptor_name | Workflow |
| mesh[10].qualifier_ui | |
| mesh[10].descriptor_ui | D001483 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | |
| mesh[10].descriptor_name | Base Sequence |
| mesh[11].qualifier_ui | Q000235 |
| mesh[11].descriptor_ui | D016086 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | genetics |
| mesh[11].descriptor_name | Lentivirus |
| mesh[12].qualifier_ui | Q000235 |
| mesh[12].descriptor_ui | D012045 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | genetics |
| mesh[12].descriptor_name | Regulatory Sequences, Nucleic Acid |
| mesh[13].qualifier_ui | Q000379 |
| mesh[13].descriptor_ui | D017422 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | methods |
| mesh[13].descriptor_name | Sequence Analysis, DNA |
| mesh[14].qualifier_ui | |
| mesh[14].descriptor_ui | D057188 |
| mesh[14].is_major_topic | True |
| mesh[14].qualifier_name | |
| mesh[14].descriptor_name | Workflow |
| mesh[15].qualifier_ui | |
| mesh[15].descriptor_ui | D001483 |
| mesh[15].is_major_topic | False |
| mesh[15].qualifier_name | |
| mesh[15].descriptor_name | Base Sequence |
| mesh[16].qualifier_ui | Q000235 |
| mesh[16].descriptor_ui | D016086 |
| mesh[16].is_major_topic | False |
| mesh[16].qualifier_name | genetics |
| mesh[16].descriptor_name | Lentivirus |
| mesh[17].qualifier_ui | Q000235 |
| mesh[17].descriptor_ui | D012045 |
| mesh[17].is_major_topic | False |
| mesh[17].qualifier_name | genetics |
| mesh[17].descriptor_name | Regulatory Sequences, Nucleic Acid |
| mesh[18].qualifier_ui | Q000379 |
| mesh[18].descriptor_ui | D017422 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | methods |
| mesh[18].descriptor_name | Sequence Analysis, DNA |
| mesh[19].qualifier_ui | |
| mesh[19].descriptor_ui | D057188 |
| mesh[19].is_major_topic | True |
| mesh[19].qualifier_name | |
| mesh[19].descriptor_name | Workflow |
| type | article |
| title | lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements |
| biblio.issue | 8 |
| biblio.volume | 15 |
| biblio.last_page | 2412 |
| biblio.first_page | 2387 |
| topics[0].id | https://openalex.org/T10521 |
| topics[0].field.id | https://openalex.org/fields/13 |
| topics[0].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[0].score | 0.9998000264167786 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/1312 |
| topics[0].subfield.display_name | Molecular Biology |
| topics[0].display_name | RNA and protein synthesis mechanisms |
| topics[1].id | https://openalex.org/T10222 |
| topics[1].field.id | https://openalex.org/fields/13 |
| topics[1].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[1].score | 0.9997000098228455 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/1312 |
| topics[1].subfield.display_name | Molecular Biology |
| topics[1].display_name | Genomics and Chromatin Dynamics |
| topics[2].id | https://openalex.org/T11482 |
| topics[2].field.id | https://openalex.org/fields/13 |
| topics[2].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[2].score | 0.9994999766349792 |
| topics[2].domain.id | https://openalex.org/domains/1 |
| topics[2].domain.display_name | Life Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/1312 |
| topics[2].subfield.display_name | Molecular Biology |
| topics[2].display_name | RNA modifications and cancer |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C2776841711 |
| concepts[0].level | 2 |
| concepts[0].score | 0.6817033886909485 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q856 |
| concepts[0].display_name | Barcode |
| concepts[1].id | https://openalex.org/C70721500 |
| concepts[1].level | 1 |
| concepts[1].score | 0.6606409549713135 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q177005 |
| concepts[1].display_name | Computational biology |
| concepts[2].id | https://openalex.org/C86803240 |
| concepts[2].level | 0 |
| concepts[2].score | 0.6068845987319946 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[2].display_name | Biology |
| concepts[3].id | https://openalex.org/C161733203 |
| concepts[3].level | 4 |
| concepts[3].score | 0.5173161029815674 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q911828 |
| concepts[3].display_name | Reporter gene |
| concepts[4].id | https://openalex.org/C51679486 |
| concepts[4].level | 3 |
| concepts[4].score | 0.5107762813568115 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q380546 |
| concepts[4].display_name | DNA sequencing |
| concepts[5].id | https://openalex.org/C104317684 |
| concepts[5].level | 2 |
| concepts[5].score | 0.49222102761268616 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q7187 |
| concepts[5].display_name | Gene |
| concepts[6].id | https://openalex.org/C21592294 |
| concepts[6].level | 4 |
| concepts[6].score | 0.4793425500392914 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q3238407 |
| concepts[6].display_name | Regulatory sequence |
| concepts[7].id | https://openalex.org/C161078062 |
| concepts[7].level | 5 |
| concepts[7].score | 0.42369741201400757 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q1068690 |
| concepts[7].display_name | Functional genomics |
| concepts[8].id | https://openalex.org/C54355233 |
| concepts[8].level | 1 |
| concepts[8].score | 0.3892073333263397 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q7162 |
| concepts[8].display_name | Genetics |
| concepts[9].id | https://openalex.org/C141231307 |
| concepts[9].level | 3 |
| concepts[9].score | 0.3794543147087097 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q7020 |
| concepts[9].display_name | Genome |
| concepts[10].id | https://openalex.org/C189206191 |
| concepts[10].level | 4 |
| concepts[10].score | 0.2895725667476654 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q222046 |
| concepts[10].display_name | Genomics |
| concepts[11].id | https://openalex.org/C165864922 |
| concepts[11].level | 3 |
| concepts[11].score | 0.2829747796058655 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q411391 |
| concepts[11].display_name | Regulation of gene expression |
| concepts[12].id | https://openalex.org/C41008148 |
| concepts[12].level | 0 |
| concepts[12].score | 0.27811262011528015 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q21198 |
| concepts[12].display_name | Computer science |
| concepts[13].id | https://openalex.org/C150194340 |
| concepts[13].level | 3 |
| concepts[13].score | 0.13646414875984192 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q26972 |
| concepts[13].display_name | Gene expression |
| concepts[14].id | https://openalex.org/C111919701 |
| concepts[14].level | 1 |
| concepts[14].score | 0.0 |
| concepts[14].wikidata | https://www.wikidata.org/wiki/Q9135 |
| concepts[14].display_name | Operating system |
| keywords[0].id | https://openalex.org/keywords/barcode |
| keywords[0].score | 0.6817033886909485 |
| keywords[0].display_name | Barcode |
| keywords[1].id | https://openalex.org/keywords/computational-biology |
| keywords[1].score | 0.6606409549713135 |
| keywords[1].display_name | Computational biology |
| keywords[2].id | https://openalex.org/keywords/biology |
| keywords[2].score | 0.6068845987319946 |
| keywords[2].display_name | Biology |
| keywords[3].id | https://openalex.org/keywords/reporter-gene |
| keywords[3].score | 0.5173161029815674 |
| keywords[3].display_name | Reporter gene |
| keywords[4].id | https://openalex.org/keywords/dna-sequencing |
| keywords[4].score | 0.5107762813568115 |
| keywords[4].display_name | DNA sequencing |
| keywords[5].id | https://openalex.org/keywords/gene |
| keywords[5].score | 0.49222102761268616 |
| keywords[5].display_name | Gene |
| keywords[6].id | https://openalex.org/keywords/regulatory-sequence |
| keywords[6].score | 0.4793425500392914 |
| keywords[6].display_name | Regulatory sequence |
| keywords[7].id | https://openalex.org/keywords/functional-genomics |
| keywords[7].score | 0.42369741201400757 |
| keywords[7].display_name | Functional genomics |
| keywords[8].id | https://openalex.org/keywords/genetics |
| keywords[8].score | 0.3892073333263397 |
| keywords[8].display_name | Genetics |
| keywords[9].id | https://openalex.org/keywords/genome |
| keywords[9].score | 0.3794543147087097 |
| keywords[9].display_name | Genome |
| keywords[10].id | https://openalex.org/keywords/genomics |
| keywords[10].score | 0.2895725667476654 |
| keywords[10].display_name | Genomics |
| keywords[11].id | https://openalex.org/keywords/regulation-of-gene-expression |
| keywords[11].score | 0.2829747796058655 |
| keywords[11].display_name | Regulation of gene expression |
| keywords[12].id | https://openalex.org/keywords/computer-science |
| keywords[12].score | 0.27811262011528015 |
| keywords[12].display_name | Computer science |
| keywords[13].id | https://openalex.org/keywords/gene-expression |
| keywords[13].score | 0.13646414875984192 |
| keywords[13].display_name | Gene expression |
| language | en |
| locations[0].id | doi:10.1038/s41596-020-0333-5 |
| locations[0].is_oa | False |
| locations[0].source.id | https://openalex.org/S109387254 |
| locations[0].source.issn | 1750-2799, 1754-2189 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 1750-2799 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Nature Protocols |
| locations[0].source.host_organization | https://openalex.org/P4310319908 |
| locations[0].source.host_organization_name | Nature Portfolio |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310319908, https://openalex.org/P4310319965 |
| locations[0].source.host_organization_lineage_names | Nature Portfolio, Springer Nature |
| locations[0].license | |
| locations[0].pdf_url | |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Nature Protocols |
| locations[0].landing_page_url | https://doi.org/10.1038/s41596-020-0333-5 |
| locations[1].id | pmid:32641802 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Nature protocols |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/32641802 |
| locations[2].id | pmh:oai:escholarship.org:ark:/13030/qt60h7c08s |
| locations[2].is_oa | False |
| locations[2].source | |
| locations[2].license | |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | article |
| locations[2].license_id | |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Nature Protocols, vol 15, iss 8 |
| locations[2].landing_page_url | https://escholarship.org/uc/item/60h7c08s |
| locations[3].id | pmh:oai:europepmc.org:6756964 |
| locations[3].is_oa | False |
| locations[3].source.id | https://openalex.org/S4306400806 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | Europe PMC (PubMed Central) |
| locations[3].source.host_organization | https://openalex.org/I1303153112 |
| locations[3].source.host_organization_name | European Bioinformatics Institute |
| locations[3].source.host_organization_lineage | https://openalex.org/I1303153112 |
| locations[3].license | |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | Text |
| locations[3].license_id | |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | |
| locations[3].landing_page_url | http://europepmc.org/pmc/articles/PMC7550205 |
| locations[4].id | pmh:oai:pubmedcentral.nih.gov:7550205 |
| locations[4].is_oa | True |
| locations[4].source.id | https://openalex.org/S2764455111 |
| locations[4].source.issn | |
| locations[4].source.type | repository |
| locations[4].source.is_oa | False |
| locations[4].source.issn_l | |
| locations[4].source.is_core | False |
| locations[4].source.is_in_doaj | False |
| locations[4].source.display_name | PubMed Central |
| locations[4].source.host_organization | https://openalex.org/I1299303238 |
| locations[4].source.host_organization_name | National Institutes of Health |
| locations[4].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[4].license | |
| locations[4].pdf_url | |
| locations[4].version | submittedVersion |
| locations[4].raw_type | Text |
| locations[4].license_id | |
| locations[4].is_accepted | False |
| locations[4].is_published | False |
| locations[4].raw_source_name | Nat Protoc |
| locations[4].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/7550205 |
| indexed_in | crossref, pubmed |
| authorships[0].author.id | https://openalex.org/A5058025321 |
| authorships[0].author.orcid | https://orcid.org/0000-0003-4321-9187 |
| authorships[0].author.display_name | M. Grace Gordon |
| authorships[0].countries | US |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I180670191 |
| authorships[0].affiliations[0].raw_affiliation_string | Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA |
| authorships[0].institutions[0].id | https://openalex.org/I180670191 |
| authorships[0].institutions[0].ror | https://ror.org/043mz5j54 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I180670191 |
| authorships[0].institutions[0].country_code | US |
| authorships[0].institutions[0].display_name | University of California, San Francisco |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | M. Grace Gordon |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA |
| authorships[1].author.id | https://openalex.org/A5024678571 |
| authorships[1].author.orcid | https://orcid.org/0000-0003-0657-434X |
| authorships[1].author.display_name | Fumitaka Inoue |
| authorships[1].countries | US |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I180670191 |
| authorships[1].affiliations[0].raw_affiliation_string | Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA |
| authorships[1].institutions[0].id | https://openalex.org/I180670191 |
| authorships[1].institutions[0].ror | https://ror.org/043mz5j54 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I180670191 |
| authorships[1].institutions[0].country_code | US |
| authorships[1].institutions[0].display_name | University of California, San Francisco |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Fumitaka Inoue |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA |
| authorships[2].author.id | https://openalex.org/A5015187444 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-9661-014X |
| authorships[2].author.display_name | Beth Martin |
| authorships[2].countries | US |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I201448701 |
| authorships[2].affiliations[0].raw_affiliation_string | Department of Genome Sciences, University of Washington, Seattle, WA, USA |
| authorships[2].institutions[0].id | https://openalex.org/I201448701 |
| authorships[2].institutions[0].ror | https://ror.org/00cvxb145 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I201448701 |
| authorships[2].institutions[0].country_code | US |
| authorships[2].institutions[0].display_name | University of Washington |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Beth Martin |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Department of Genome Sciences, University of Washington, Seattle, WA, USA |
| authorships[3].author.id | https://openalex.org/A5060365341 |
| authorships[3].author.orcid | https://orcid.org/0000-0002-2032-6679 |
| authorships[3].author.display_name | Max Schubach |
| authorships[3].countries | DE |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I4210139777 |
| authorships[3].affiliations[0].raw_affiliation_string | Berlin Institute of Health (BIH), Berlin, Germany |
| authorships[3].institutions[0].id | https://openalex.org/I4210139777 |
| authorships[3].institutions[0].ror | https://ror.org/0493xsw21 |
| authorships[3].institutions[0].type | facility |
| authorships[3].institutions[0].lineage | https://openalex.org/I4210139777, https://openalex.org/I7877124 |
| authorships[3].institutions[0].country_code | DE |
| authorships[3].institutions[0].display_name | Berlin Institute of Health at Charité - Universitätsmedizin Berlin |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Max Schubach |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Berlin Institute of Health (BIH), Berlin, Germany |
| authorships[4].author.id | https://openalex.org/A5081544816 |
| authorships[4].author.orcid | https://orcid.org/0000-0001-8148-952X |
| authorships[4].author.display_name | Vikram Agarwal |
| authorships[4].countries | US |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I201448701 |
| authorships[4].affiliations[0].raw_affiliation_string | Department of Genome Sciences, University of Washington, Seattle, WA, USA |
| authorships[4].institutions[0].id | https://openalex.org/I201448701 |
| authorships[4].institutions[0].ror | https://ror.org/00cvxb145 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I201448701 |
| authorships[4].institutions[0].country_code | US |
| authorships[4].institutions[0].display_name | University of Washington |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Vikram Agarwal |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Department of Genome Sciences, University of Washington, Seattle, WA, USA |
| authorships[5].author.id | https://openalex.org/A5039266926 |
| authorships[5].author.orcid | https://orcid.org/0000-0002-6648-3610 |
| authorships[5].author.display_name | Sean Whalen |
| authorships[5].countries | US |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I1321430492 |
| authorships[5].affiliations[0].raw_affiliation_string | Gladstone Institutes, San Francisco, CA, USA |
| authorships[5].institutions[0].id | https://openalex.org/I1321430492 |
| authorships[5].institutions[0].ror | https://ror.org/038321296 |
| authorships[5].institutions[0].type | nonprofit |
| authorships[5].institutions[0].lineage | https://openalex.org/I1321430492 |
| authorships[5].institutions[0].country_code | US |
| authorships[5].institutions[0].display_name | Gladstone Institutes |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Sean Whalen |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Gladstone Institutes, San Francisco, CA, USA |
| authorships[6].author.id | https://openalex.org/A5110071012 |
| authorships[6].author.orcid | |
| authorships[6].author.display_name | Shiyun Feng |
| authorships[6].countries | US |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I180670191 |
| authorships[6].affiliations[0].raw_affiliation_string | Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA |
| authorships[6].institutions[0].id | https://openalex.org/I180670191 |
| authorships[6].institutions[0].ror | https://ror.org/043mz5j54 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I180670191 |
| authorships[6].institutions[0].country_code | US |
| authorships[6].institutions[0].display_name | University of California, San Francisco |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Shiyun Feng |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA |
| authorships[7].author.id | https://openalex.org/A5101979492 |
| authorships[7].author.orcid | https://orcid.org/0000-0003-3802-8220 |
| authorships[7].author.display_name | Jingjing Zhao |
| authorships[7].countries | US |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I180670191 |
| authorships[7].affiliations[0].raw_affiliation_string | Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA |
| authorships[7].institutions[0].id | https://openalex.org/I180670191 |
| authorships[7].institutions[0].ror | https://ror.org/043mz5j54 |
| authorships[7].institutions[0].type | education |
| authorships[7].institutions[0].lineage | https://openalex.org/I180670191 |
| authorships[7].institutions[0].country_code | US |
| authorships[7].institutions[0].display_name | University of California, San Francisco |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Jingjing Zhao |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA |
| authorships[8].author.id | https://openalex.org/A5062245235 |
| authorships[8].author.orcid | https://orcid.org/0000-0003-1939-0865 |
| authorships[8].author.display_name | Tal Ashuach |
| authorships[8].countries | US |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I95457486 |
| authorships[8].affiliations[0].raw_affiliation_string | Department of Electrical Engineering and Computer Sciences and Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA |
| authorships[8].institutions[0].id | https://openalex.org/I95457486 |
| authorships[8].institutions[0].ror | https://ror.org/01an7q238 |
| authorships[8].institutions[0].type | education |
| authorships[8].institutions[0].lineage | https://openalex.org/I95457486 |
| authorships[8].institutions[0].country_code | US |
| authorships[8].institutions[0].display_name | University of California, Berkeley |
| authorships[8].author_position | middle |
| authorships[8].raw_author_name | Tal Ashuach |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | Department of Electrical Engineering and Computer Sciences and Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA |
| authorships[9].author.id | https://openalex.org/A5006765574 |
| authorships[9].author.orcid | |
| authorships[9].author.display_name | Ryan Ziffra |
| authorships[9].countries | US |
| authorships[9].affiliations[0].institution_ids | https://openalex.org/I180670191 |
| authorships[9].affiliations[0].raw_affiliation_string | Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA |
| authorships[9].institutions[0].id | https://openalex.org/I180670191 |
| authorships[9].institutions[0].ror | https://ror.org/043mz5j54 |
| authorships[9].institutions[0].type | education |
| authorships[9].institutions[0].lineage | https://openalex.org/I180670191 |
| authorships[9].institutions[0].country_code | US |
| authorships[9].institutions[0].display_name | University of California, San Francisco |
| authorships[9].author_position | middle |
| authorships[9].raw_author_name | Ryan Ziffra |
| authorships[9].is_corresponding | False |
| authorships[9].raw_affiliation_strings | Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA |
| authorships[10].author.id | https://openalex.org/A5069469702 |
| authorships[10].author.orcid | https://orcid.org/0000-0002-3066-5498 |
| authorships[10].author.display_name | Anat Kreimer |
| authorships[10].countries | US |
| authorships[10].affiliations[0].institution_ids | https://openalex.org/I180670191 |
| authorships[10].affiliations[0].raw_affiliation_string | Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA |
| authorships[10].institutions[0].id | https://openalex.org/I180670191 |
| authorships[10].institutions[0].ror | https://ror.org/043mz5j54 |
| authorships[10].institutions[0].type | education |
| authorships[10].institutions[0].lineage | https://openalex.org/I180670191 |
| authorships[10].institutions[0].country_code | US |
| authorships[10].institutions[0].display_name | University of California, San Francisco |
| authorships[10].author_position | middle |
| authorships[10].raw_author_name | Anat Kreimer |
| authorships[10].is_corresponding | False |
| authorships[10].raw_affiliation_strings | Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA |
| authorships[11].author.id | https://openalex.org/A5055883774 |
| authorships[11].author.orcid | https://orcid.org/0000-0003-3641-1488 |
| authorships[11].author.display_name | Ilias Georgakopoulos‐Soares |
| authorships[11].countries | US |
| authorships[11].affiliations[0].institution_ids | https://openalex.org/I180670191 |
| authorships[11].affiliations[0].raw_affiliation_string | Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA |
| authorships[11].institutions[0].id | https://openalex.org/I180670191 |
| authorships[11].institutions[0].ror | https://ror.org/043mz5j54 |
| authorships[11].institutions[0].type | education |
| authorships[11].institutions[0].lineage | https://openalex.org/I180670191 |
| authorships[11].institutions[0].country_code | US |
| authorships[11].institutions[0].display_name | University of California, San Francisco |
| authorships[11].author_position | middle |
| authorships[11].raw_author_name | Ilias Georgakopoulos-Soares |
| authorships[11].is_corresponding | False |
| authorships[11].raw_affiliation_strings | Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA |
| authorships[12].author.id | https://openalex.org/A5026299103 |
| authorships[12].author.orcid | https://orcid.org/0000-0001-9004-1225 |
| authorships[12].author.display_name | Nir Yosef |
| authorships[12].countries | US |
| authorships[12].affiliations[0].institution_ids | https://openalex.org/I95457486 |
| authorships[12].affiliations[0].raw_affiliation_string | Department of Electrical Engineering and Computer Sciences and Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA |
| authorships[12].institutions[0].id | https://openalex.org/I95457486 |
| authorships[12].institutions[0].ror | https://ror.org/01an7q238 |
| authorships[12].institutions[0].type | education |
| authorships[12].institutions[0].lineage | https://openalex.org/I95457486 |
| authorships[12].institutions[0].country_code | US |
| authorships[12].institutions[0].display_name | University of California, Berkeley |
| authorships[12].author_position | middle |
| authorships[12].raw_author_name | Nir Yosef |
| authorships[12].is_corresponding | False |
| authorships[12].raw_affiliation_strings | Department of Electrical Engineering and Computer Sciences and Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA |
| authorships[13].author.id | https://openalex.org/A5005819504 |
| authorships[13].author.orcid | https://orcid.org/0000-0001-6560-3783 |
| authorships[13].author.display_name | Chun Ye |
| authorships[13].countries | US |
| authorships[13].affiliations[0].institution_ids | https://openalex.org/I180670191 |
| authorships[13].affiliations[0].raw_affiliation_string | Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA |
| authorships[13].institutions[0].id | https://openalex.org/I180670191 |
| authorships[13].institutions[0].ror | https://ror.org/043mz5j54 |
| authorships[13].institutions[0].type | education |
| authorships[13].institutions[0].lineage | https://openalex.org/I180670191 |
| authorships[13].institutions[0].country_code | US |
| authorships[13].institutions[0].display_name | University of California, San Francisco |
| authorships[13].author_position | middle |
| authorships[13].raw_author_name | Chun Jimmie Ye |
| authorships[13].is_corresponding | False |
| authorships[13].raw_affiliation_strings | Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA |
| authorships[14].author.id | https://openalex.org/A5005062415 |
| authorships[14].author.orcid | https://orcid.org/0000-0002-9870-6196 |
| authorships[14].author.display_name | Katherine S. Pollard |
| authorships[14].countries | US |
| authorships[14].affiliations[0].institution_ids | https://openalex.org/I180670191 |
| authorships[14].affiliations[0].raw_affiliation_string | Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA |
| authorships[14].institutions[0].id | https://openalex.org/I180670191 |
| authorships[14].institutions[0].ror | https://ror.org/043mz5j54 |
| authorships[14].institutions[0].type | education |
| authorships[14].institutions[0].lineage | https://openalex.org/I180670191 |
| authorships[14].institutions[0].country_code | US |
| authorships[14].institutions[0].display_name | University of California, San Francisco |
| authorships[14].author_position | middle |
| authorships[14].raw_author_name | Katherine S. Pollard |
| authorships[14].is_corresponding | False |
| authorships[14].raw_affiliation_strings | Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA |
| authorships[15].author.id | https://openalex.org/A5083897996 |
| authorships[15].author.orcid | https://orcid.org/0000-0002-1516-1865 |
| authorships[15].author.display_name | Jay Shendure |
| authorships[15].countries | US |
| authorships[15].affiliations[0].institution_ids | https://openalex.org/I201448701 |
| authorships[15].affiliations[0].raw_affiliation_string | Department of Genome Sciences, University of Washington, Seattle, WA, USA |
| authorships[15].institutions[0].id | https://openalex.org/I201448701 |
| authorships[15].institutions[0].ror | https://ror.org/00cvxb145 |
| authorships[15].institutions[0].type | education |
| authorships[15].institutions[0].lineage | https://openalex.org/I201448701 |
| authorships[15].institutions[0].country_code | US |
| authorships[15].institutions[0].display_name | University of Washington |
| authorships[15].author_position | middle |
| authorships[15].raw_author_name | Jay Shendure |
| authorships[15].is_corresponding | False |
| authorships[15].raw_affiliation_strings | Department of Genome Sciences, University of Washington, Seattle, WA, USA |
| authorships[16].author.id | https://openalex.org/A5082477584 |
| authorships[16].author.orcid | https://orcid.org/0000-0001-9278-5471 |
| authorships[16].author.display_name | Martin Kircher |
| authorships[16].countries | DE |
| authorships[16].affiliations[0].institution_ids | https://openalex.org/I4210139777 |
| authorships[16].affiliations[0].raw_affiliation_string | Berlin Institute of Health (BIH), Berlin, Germany |
| authorships[16].institutions[0].id | https://openalex.org/I4210139777 |
| authorships[16].institutions[0].ror | https://ror.org/0493xsw21 |
| authorships[16].institutions[0].type | facility |
| authorships[16].institutions[0].lineage | https://openalex.org/I4210139777, https://openalex.org/I7877124 |
| authorships[16].institutions[0].country_code | DE |
| authorships[16].institutions[0].display_name | Berlin Institute of Health at Charité - Universitätsmedizin Berlin |
| authorships[16].author_position | middle |
| authorships[16].raw_author_name | Martin Kircher |
| authorships[16].is_corresponding | False |
| authorships[16].raw_affiliation_strings | Berlin Institute of Health (BIH), Berlin, Germany |
| authorships[17].author.id | https://openalex.org/A5086687499 |
| authorships[17].author.orcid | https://orcid.org/0000-0002-7434-8144 |
| authorships[17].author.display_name | Nadav Ahituv |
| authorships[17].countries | US |
| authorships[17].affiliations[0].institution_ids | https://openalex.org/I180670191 |
| authorships[17].affiliations[0].raw_affiliation_string | Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA |
| authorships[17].institutions[0].id | https://openalex.org/I180670191 |
| authorships[17].institutions[0].ror | https://ror.org/043mz5j54 |
| authorships[17].institutions[0].type | education |
| authorships[17].institutions[0].lineage | https://openalex.org/I180670191 |
| authorships[17].institutions[0].country_code | US |
| authorships[17].institutions[0].display_name | University of California, San Francisco |
| authorships[17].author_position | last |
| authorships[17].raw_author_name | Nadav Ahituv |
| authorships[17].is_corresponding | False |
| authorships[17].raw_affiliation_strings | Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.ncbi.nlm.nih.gov/pmc/articles/7550205 |
| open_access.oa_status | green |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10521 |
| primary_topic.field.id | https://openalex.org/fields/13 |
| primary_topic.field.display_name | Biochemistry, Genetics and Molecular Biology |
| primary_topic.score | 0.9998000264167786 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/1312 |
| primary_topic.subfield.display_name | Molecular Biology |
| primary_topic.display_name | RNA and protein synthesis mechanisms |
| related_works | https://openalex.org/W2256570403, https://openalex.org/W2074156223, https://openalex.org/W4391927655, https://openalex.org/W2103246366, https://openalex.org/W2901653204, https://openalex.org/W2069600476, https://openalex.org/W2057334520, https://openalex.org/W2557259592, https://openalex.org/W2807291864, https://openalex.org/W2056528138 |
| cited_by_count | 139 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 48 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 31 |
| counts_by_year[2].year | 2023 |
| counts_by_year[2].cited_by_count | 26 |
| counts_by_year[3].year | 2022 |
| counts_by_year[3].cited_by_count | 17 |
| counts_by_year[4].year | 2021 |
| counts_by_year[4].cited_by_count | 11 |
| counts_by_year[5].year | 2020 |
| counts_by_year[5].cited_by_count | 6 |
| locations_count | 5 |
| best_oa_location.id | pmh:oai:pubmedcentral.nih.gov:7550205 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2764455111 |
| best_oa_location.source.issn | |
| best_oa_location.source.type | repository |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | |
| best_oa_location.source.is_core | False |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | PubMed Central |
| best_oa_location.source.host_organization | https://openalex.org/I1299303238 |
| best_oa_location.source.host_organization_name | National Institutes of Health |
| best_oa_location.source.host_organization_lineage | https://openalex.org/I1299303238 |
| best_oa_location.license | |
| best_oa_location.pdf_url | |
| best_oa_location.version | submittedVersion |
| best_oa_location.raw_type | Text |
| best_oa_location.license_id | |
| best_oa_location.is_accepted | False |
| best_oa_location.is_published | False |
| best_oa_location.raw_source_name | Nat Protoc |
| best_oa_location.landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/7550205 |
| primary_location.id | doi:10.1038/s41596-020-0333-5 |
| primary_location.is_oa | False |
| primary_location.source.id | https://openalex.org/S109387254 |
| primary_location.source.issn | 1750-2799, 1754-2189 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 1750-2799 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Nature Protocols |
| primary_location.source.host_organization | https://openalex.org/P4310319908 |
| primary_location.source.host_organization_name | Nature Portfolio |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310319908, https://openalex.org/P4310319965 |
| primary_location.source.host_organization_lineage_names | Nature Portfolio, Springer Nature |
| primary_location.license | |
| primary_location.pdf_url | |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Nature Protocols |
| primary_location.landing_page_url | https://doi.org/10.1038/s41596-020-0333-5 |
| publication_date | 2020-07-08 |
| publication_year | 2020 |
| referenced_works | https://openalex.org/W2581818460, https://openalex.org/W1980991473, https://openalex.org/W2078059415, https://openalex.org/W1999027354, https://openalex.org/W2129795133, https://openalex.org/W2150111516, https://openalex.org/W2122818453, https://openalex.org/W2117757143, https://openalex.org/W2757704052, https://openalex.org/W2090037139, https://openalex.org/W655820313, https://openalex.org/W2077874719, https://openalex.org/W2605897695, https://openalex.org/W2553600202, https://openalex.org/W4248967711, https://openalex.org/W2970956693, https://openalex.org/W2981212141, https://openalex.org/W2791526924, https://openalex.org/W2967059818, https://openalex.org/W3029661147, https://openalex.org/W2513205199, https://openalex.org/W2790738458, https://openalex.org/W2103441770, https://openalex.org/W2170551349, https://openalex.org/W2260669749, https://openalex.org/W3092421956 |
| referenced_works_count | 26 |
| abstract_inverted_index | |
| cited_by_percentile_year.max | 100 |
| cited_by_percentile_year.min | 98 |
| countries_distinct_count | 2 |
| institutions_distinct_count | 18 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/9 |
| sustainable_development_goals[0].score | 0.44999998807907104 |
| sustainable_development_goals[0].display_name | Industry, innovation and infrastructure |
| citation_normalized_percentile.value | 0.96746897 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |