Lessons from applied large-scale pooling of 133,816 SARS-CoV-2 RT-PCR tests Article Swipe

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Netta Barak , Roni Ben‐Ami , Tal Sido , Amir Perri , Aviad Shtoyer , Mila Rivkin , Tamar Licht , Ayelet Peretz , Judith Magenheim , Irit Fogel , Ayalah Livneh , Yutti Daitch , Esther Oiknine‐Djian , Gil Benedek , Yuval Dor , Dana G. Wolf , Moran Yassour , Agnes Klochendler , Amir Eden , Amar J. S. Klar , A. Geldman , Ayelet Arbel , Batel Shalom , Bracha Lea Ochana , D. Avrahami-Tzfati , Daniel Neiman , David Steinberg , Dikla Ben Zvi , Etai Shpigel , Gal Atlan , Harvey G. Klein , H. Chekroun , Hagit Shani , Itay Hazan , Irfan Ahmad Ansari , I. Magenheim , J. Moss , Lior Peretz , L. Feigin , M. Saraby , Melanie A. Sherman , Michelle Bentata , Michel Avital , Matthew Kott , M. Reuben Peyser , Martin Weitz , Mordechai Shacham , Maria Grünewald , Noah J. Sasson , N. Wallis , Narmen Azazmeh , N. Tzarum , O. Fridlich , R Sher , Reba Condiotti , Ron Refaeli , R. Zaken-Gallili , R. Gayman Helman , S. Ofek , S. Tzaban , Sheina Piyanzin , S. Anzi , Shlomo Dagan , S. Lilenthal , T. Friehmann , Yotam Kaufman , Ann Saada , Arie Dekel , A. Yeffet , Avraham Shaag , Ayelet Michael-Gayego , Elizabeth Shay , E. Arbib , Hadil Onallah , Kerem Ben‐Meir , L. Levinzon , Leonor Cohen‐Daniel , L. Natan , Muhammad Hamdan , M. Shwieki , Olesya Vorontsov , Rima Barsuk , R. Abramovitch , R. Gutorov , Salim Sirhan , Sanofar Abdeen , Y. Yachnin , Hadar Golan-Berman , Eitan Amir , Tema Fridman , E. Chabube Kripper , T. Miriam Rohrlich , G. Batshon , L. Mendelovitz ·

YOU? · · 2021 · Open Access · · DOI: https://doi.org/10.1126/scitranslmed.abf2823

Adaptive sample pooling for SARS-CoV-2 testing based on positivity rates spares 76% of test reactions without compromising specificity or sensitivity.

Related Topics

Sars-Cov-2

Covid-19 Pandemic

Medicine

Computational Biology

Biology

Internal Medicine

Computer Science

Artificial Intelligence

Cartography

Geography

Outbreak (2024 Film)

Infectious Diseases (Medical Specialty)

Disease

Concepts

Pooling Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Coronavirus disease 2019 (COVID-19) 2019-20 coronavirus outbreak Sars virus Medicine Scale (ratio) Virology Computational biology Biology Internal medicine Computer science Artificial intelligence Cartography Geography Outbreak Infectious disease (medical specialty) Disease

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Type: article
Language: en
Landing Page: https://doi.org/10.1126/scitranslmed.abf2823
OA Status: hybrid
Cited By: 99
References: 26
Related Works: 10
OpenAlex ID: https://openalex.org/W3131509040

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OpenAlex ID: https://openalex.org/W3131509040

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DOI: https://doi.org/10.1126/scitranslmed.abf2823

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Title: Lessons from applied large-scale pooling of 133,816 SARS-CoV-2 RT-PCR tests

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Type: article

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Language: en

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Publication year: 2021

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Publication date: 2021-02-22

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Authors: Netta Barak, Roni Ben‐Ami, Tal Sido, Amir Perri, Aviad Shtoyer, Mila Rivkin, Tamar Licht, Ayelet Peretz, Judith Magenheim, Irit Fogel, Ayalah Livneh, Yutti Daitch, Esther Oiknine‐Djian, Gil Benedek, Yuval Dor, Dana G. Wolf, Moran Yassour, Agnes Klochendler, Amir Eden, Amar J. S. Klar, A. Geldman, Ayelet Arbel, Batel Shalom, Bracha Lea Ochana, D. Avrahami-Tzfati, Daniel Neiman, David Steinberg, Dikla Ben Zvi, Etai Shpigel, Gal Atlan, Harvey G. Klein, H. Chekroun, Hagit Shani, Itay Hazan, Irfan Ahmad Ansari, I. Magenheim, J. Moss, Lior Peretz, L. Feigin, M. Saraby, Melanie A. Sherman, Michelle Bentata, Michel Avital, Matthew Kott, M. Reuben Peyser, Martin Weitz, Mordechai Shacham, Maria Grünewald, Noah J. Sasson, N. Wallis, Narmen Azazmeh, N. Tzarum, O. Fridlich, R Sher, Reba Condiotti, Ron Refaeli, R. Zaken-Gallili, R. Gayman Helman, S. Ofek, S. Tzaban, Sheina Piyanzin, S. Anzi, Shlomo Dagan, S. Lilenthal, T. Friehmann, Yotam Kaufman, Ann Saada, Arie Dekel, A. Yeffet, Avraham Shaag, Ayelet Michael-Gayego, Elizabeth Shay, E. Arbib, Hadil Onallah, Kerem Ben‐Meir, L. Levinzon, Leonor Cohen‐Daniel, L. Natan, Muhammad Hamdan, M. Shwieki, Olesya Vorontsov, Rima Barsuk, R. Abramovitch, R. Gutorov, Salim Sirhan, Sanofar Abdeen, Y. Yachnin, Hadar Golan-Berman, Eitan Amir, Tema Fridman, E. Chabube Kripper, T. Miriam Rohrlich, G. Batshon, L. Mendelovitz

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Landing page: https://doi.org/10.1126/scitranslmed.abf2823

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Open access: Yes

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OA status: hybrid

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OA URL: https://doi.org/10.1126/scitranslmed.abf2823

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Concepts: Pooling, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Coronavirus disease 2019 (COVID-19), 2019-20 coronavirus outbreak, Sars virus, Medicine, Scale (ratio), Virology, Computational biology, Biology, Internal medicine, Computer science, Artificial intelligence, Cartography, Geography, Outbreak, Infectious disease (medical specialty), Disease

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Cited by: 99

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Citations by year (recent): 2025: 11, 2024: 17, 2023: 17, 2022: 23, 2021: 30

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References (count): 26

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Related works (count): 10

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