Leukoderma and chronic inflammatory demyelinating polyradiculoneuropathy in an adolescent with graft-versus-host disease Article Swipe
Gökhan Okan
,
Fatih Erbey
,
Mehmet Sait Durmuş
,
Gülyüz Öztürk
·
YOU?
·
· 2015
· Open Access
·
· DOI: https://doi.org/10.5472/mmjcr.2802.10
YOU?
·
· 2015
· Open Access
·
· DOI: https://doi.org/10.5472/mmjcr.2802.10
A 15-year-old Iraqi male patient with acute lymphoblastic leukemia received an allogeneic bone marrow transplant from his brother. On the 18th day after the transplant, the patient developed grade II acute graft-versus-host disease, and treatment included methylprednisolone. On day 140, the patient was diagnosed with leukoderma. On day 150, the patient was admitted to hospital because of numbness and muscle weakness in the extremities and a disturbance of the gait. Neurologic examination showed muscle weakness in the upper and lower extremities and there were no deep tendon reflexes. Nerve conduction studies showed reduced conduction speeds of the motor nerves with demyelinating features. The patient was diagnosed as having a chronic inflammatory demyelinating polyradiculoneuropathy (CIDB) based on clinical and electrophysiological findings. Treatment included methylprednisolone and intravenous immunoglobulin. The neurologic function improved but the skin lesions persisted.This case shows that graft-versus-host disease can act as a triggering factor for the appearance of autoimmune diseases.Keywords: Leukemia, Graft-versus-host disease, Leukoderma, Chronic inflammatory demyelinating polyneuropathy
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Concepts
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.5472/mmjcr.2802.10
- OA Status
- gold
- References
- 10
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- OpenAlex ID
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All OpenAlex metadata
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https://openalex.org/W2178870942Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.5472/mmjcr.2802.10Digital Object Identifier
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Leukoderma and chronic inflammatory demyelinating polyradiculoneuropathy in an adolescent with graft-versus-host diseaseWork title
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articleOpenAlex work type
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enPrimary language
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2015Year of publication
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2015-01-01Full publication date if available
- Authors
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Gökhan Okan, Fatih Erbey, Mehmet Sait Durmuş, Gülyüz ÖztürkList of authors in order
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https://doi.org/10.5472/mmjcr.2802.10Publisher landing page
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goldOpen access status per OpenAlex
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https://dergipark.org.tr/en/download/article-file/470589Direct OA link when available
- Concepts
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Medicine, Methylprednisolone, Polyradiculoneuropathy, Weakness, Surgery, Graft-versus-host disease, Chronic inflammatory demyelinating polyneuropathy, Transplantation, Immunology, Guillain-Barre syndrome, AntibodyTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
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10Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.Leukoderma, | 155 |
| abstract_inverted_index.disturbance | 66 |
| abstract_inverted_index.examination | 71 |
| abstract_inverted_index.extremities | 63, 80 |
| abstract_inverted_index.intravenous | 124 |
| abstract_inverted_index.leukoderma. | 45 |
| abstract_inverted_index.transplant, | 24 |
| abstract_inverted_index.inflammatory | 110, 157 |
| abstract_inverted_index.demyelinating | 100, 111, 158 |
| abstract_inverted_index.lymphoblastic | 7 |
| abstract_inverted_index.persisted.This | 134 |
| abstract_inverted_index.polyneuropathy | 159 |
| abstract_inverted_index.immunoglobulin. | 125 |
| abstract_inverted_index.Graft-versus-host | 153 |
| abstract_inverted_index.graft-versus-host | 31, 138 |
| abstract_inverted_index.diseases.Keywords: | 151 |
| abstract_inverted_index.methylprednisolone | 122 |
| abstract_inverted_index.methylprednisolone. | 36 |
| abstract_inverted_index.electrophysiological | 118 |
| abstract_inverted_index.polyradiculoneuropathy | 112 |
| cited_by_percentile_year | |
| countries_distinct_count | 1 |
| institutions_distinct_count | 4 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.8799999952316284 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.07857535 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |