Levotiroxina para hipotireoidismo subclínico: todos os pacientes devem ser tratados? Article Swipe

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Ignacio Del Villar , Milena Nunes Alves de Sousa ·

YOU? · · 2025 · Open Access · · DOI: https://doi.org/10.18378/rbfh.v14i1.11166

- O hipotireoidismo subclínico é uma condição endocrinológica caracterizada por níveis elevados de hormônio estimulante da tireoide (TSH) associados a níveis normais de tri-iodotironina e tiroxina livre. Quando necessária, a abordagem terapêutica geralmente adotada é a utilização de levotiroxina. Tendo em vista a importância da análise dos desdobramentos do manejo do hipotireoidismo subclínico, este estudo tem por objetivo de investigar se a levotiroxina pode ser considerada uma opção terapêutica para todos os casos de hiportireoidismo subclínico e propor uma diretriz clínica. Trata-se de uma revisão integrativa da literatura realizada no âmbito das bases de dados National Library of Medicine Medical Literature Analysis and Retrieval System Online, Literatura Latino-Americana e do Caribe em Ciência da Saúde, Base de Dados em Enfermagem e Scientific Electronic Library Online. Incluiu-se estudos nos idiomas inglês, português e espanhol; publicados no período de 2019 a 2024 e que abordavam as temáticas propostas para esta pesquisa e que estavam disponibilizados na íntegra e de forma gratuita. Após a aplicação dos filtros com relação aos critérios de inclusão, restaram 15 artigos para compor a análise proposta. Os estudos evidenciaram que a reposição de levotiroxina em adultos deve ser iniciada diante de níveis de TSH levemente aumentado (4,0mU/mL a 10,0mU/mL). Embora o hipotireoidismo subclínico seja uma situação comum, sobretudo em idosos, a respeito da indicação de seu tratamento, recomenda-se cautela.

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Title: Levotiroxina para hipotireoidismo subclínico: todos os pacientes devem ser tratados?

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Publication year: 2025

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Authors: Ignacio Del Villar, Milena Nunes Alves de Sousa

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Landing page: https://doi.org/10.18378/rbfh.v14i1.11166

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