Lifestyle, caries, and apical periodontitis: Results from a university‐based cross‐sectional study Article Swipe
YOU?
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· 2024
· Open Access
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· DOI: https://doi.org/10.1111/iej.14165
Aim Lifestyle factors significantly influence the development of inflammatory diseases, and emerging evidence suggests they may also impact oral health. However, no studies have explored their role in apical periodontitis (AP) amongst adults. This study aimed to assess the association between adherence to the Mediterranean diet (MD), physical activity, perceived stress, and sleep quality with the periapical and caries status in a university‐based cohort. Methodology A total of 149 periodontally healthy patients were included in the study. Clinical assessments and radiographic examinations [Orthopantomography (opt) and periapical radiographs] were conducted to evaluate the periapical status. Data on their periapical index (PAI) score and the decayed, missing and filled teeth (DMFT) index were recorded. Validated questionnaires were used to investigate patient's lifestyles. A final logistic regression model was performed for the multivariable analysis to evaluate the predictive ability of adherence to Mediterranean lifestyle on the presence of AP; other local, systemic and environmental factors were included as independent factors in the model. Results Significant associations were observed between AP and high/low adherence to the MD ( p = .00), high/low‐moderate physical activity ( p = .00), high/low sleep quality ( p = .00) and high/low perceived stress ( p = .00). The final multivariable regression model showed that low adherence to MD (OR = 3.68; 95% confidence interval [CI]: 1.24–10.83; p = . 01) and reduced sleep quality (OR = 3.04; 95% CI: 1.42–6.50; p = .00) were identified as potential risk factors for AP development. On the other hand, the DMFT index showed no significant association with lifestyle factors (OR = 1.0; CI: 1.01–1.14; p = .02) but was correlated with the development of AP (OR = 1.07; CI: 1.01–1.14; p = .02). Conclusion Results from the present study suggest a potential association between low adherence to MD and reduced sleep quality with the development of AP. Individuals with low adherence to MD and inadequate sleep quality faced respectively 4‐fold and 3‐fold increased odds of developing periapical lesions. Further research is essential to elucidate the causal mechanisms underlying these associations and to determine whether lifestyle adjustments could improve endodontic success rate.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1111/iej.14165
- OA Status
- hybrid
- Cited By
- 5
- References
- 59
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4404276396
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4404276396Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1111/iej.14165Digital Object Identifier
- Title
-
Lifestyle, caries, and apical periodontitis: Results from a university‐based cross‐sectional studyWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-11-12Full publication date if available
- Authors
-
Carlo Gaeta, Giulia Malvicini, Dominga Di Lascio, Marco Martignoni, Gian Maria Ragucci, Simone Grandini, Crystal MarrugantiList of authors in order
- Landing page
-
https://doi.org/10.1111/iej.14165Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
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hybridOpen access status per OpenAlex
- OA URL
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https://doi.org/10.1111/iej.14165Direct OA link when available
- Concepts
-
Medicine, Logistic regression, Periodontitis, Confidence interval, Cross-sectional study, Mediterranean diet, Dentistry, Cohort, Cohort study, Internal medicine, Odds ratio, PathologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
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5Total citation count in OpenAlex
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2025: 5Per-year citation counts (last 5 years)
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59Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.potential | 239, 291 |
| abstract_inverted_index.recorded. | 112 |
| abstract_inverted_index.Conclusion | 283 |
| abstract_inverted_index.confidence | 215 |
| abstract_inverted_index.correlated | 269 |
| abstract_inverted_index.developing | 325 |
| abstract_inverted_index.endodontic | 348 |
| abstract_inverted_index.identified | 237 |
| abstract_inverted_index.inadequate | 314 |
| abstract_inverted_index.mechanisms | 336 |
| abstract_inverted_index.periapical | 57, 86, 93, 98, 326 |
| abstract_inverted_index.predictive | 135 |
| abstract_inverted_index.regression | 124, 203 |
| abstract_inverted_index.underlying | 337 |
| abstract_inverted_index.Individuals | 307 |
| abstract_inverted_index.Methodology | 65 |
| abstract_inverted_index.Significant | 162 |
| abstract_inverted_index.adjustments | 345 |
| abstract_inverted_index.assessments | 79 |
| abstract_inverted_index.association | 40, 255, 292 |
| abstract_inverted_index.development | 7, 272, 304 |
| abstract_inverted_index.independent | 156 |
| abstract_inverted_index.investigate | 118 |
| abstract_inverted_index.lifestyles. | 120 |
| abstract_inverted_index.significant | 254 |
| abstract_inverted_index.1.01–1.14; | 263, 279 |
| abstract_inverted_index.1.42–6.50; | 232 |
| abstract_inverted_index.associations | 163, 339 |
| abstract_inverted_index.development. | 244 |
| abstract_inverted_index.examinations | 82 |
| abstract_inverted_index.inflammatory | 9 |
| abstract_inverted_index.radiographic | 81 |
| abstract_inverted_index.radiographs] | 87 |
| abstract_inverted_index.respectively | 318 |
| abstract_inverted_index.1.24–10.83; | 218 |
| abstract_inverted_index.Mediterranean | 45, 140 |
| abstract_inverted_index.environmental | 151 |
| abstract_inverted_index.multivariable | 130, 202 |
| abstract_inverted_index.periodontally | 70 |
| abstract_inverted_index.periodontitis | 30 |
| abstract_inverted_index.significantly | 4 |
| abstract_inverted_index.questionnaires | 114 |
| abstract_inverted_index.university‐based | 63 |
| abstract_inverted_index.[Orthopantomography | 83 |
| abstract_inverted_index.high/low‐moderate | 178 |
| cited_by_percentile_year.max | 99 |
| cited_by_percentile_year.min | 98 |
| corresponding_author_ids | https://openalex.org/A5009511759 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 7 |
| corresponding_institution_ids | https://openalex.org/I102064193 |
| citation_normalized_percentile.value | 0.90868134 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |