Light-Driven Catalytic Regulation of Enzymes at the Interface with Plasmonic Nanomaterials Article Swipe
Heloise Ribeiro de Barros
,
Fernando López‐Gallego
,
Luis M. Liz‐Marzán
·
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1021/acs.biochem.0c00447
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1021/acs.biochem.0c00447
Regulation of enzymes is highly relevant toward orchestrating cell-free and stepwise biotransformations, thereby maximizing their overall performance. Plasmonic nanomaterials offer a great opportunity to tune the functionality of enzymes through their remarkable optical properties. Localized surface plasmon resonances (LSPR) can be used to modify chemical transformations at the nanomaterial's surface, upon light irradiation. Incident light can promote energetic processes, which may be related to an increase of local temperature (photothermal effects) but also to effects triggered by generated hotspots or hot electrons (photoelectronic effects). As a consequence, light irradiation of the protein-nanomaterial interface affects enzyme functionality. To harness these effects to finely and remotely regulate enzyme activity, the physicochemical features of the nanomaterial, properties of the incident light, and parameters governing molecular interactions must be optimized. In this Perspective, we discuss relevant examples that illustrate the use of plasmonic nanoparticles to control enzyme function through LSPR excitation. Finally, we also highlight the importance of expanding the use of plasmonic nanomaterials to the immobilization of multienzyme systems for light-driven regulation of cell-free biosynthetic pathways. Although this concept is living its infancy, we encourage the scientific community to advance in the development of novel light-controlled biocatalytic plasmonic nanoconjugates and explore their application in biosensing, applied biocatalysis, and biomedicine.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1021/acs.biochem.0c00447
- OA Status
- green
- Cited By
- 15
- References
- 52
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3040862332
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W3040862332Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1021/acs.biochem.0c00447Digital Object Identifier
- Title
-
Light-Driven Catalytic Regulation of Enzymes at the Interface with Plasmonic NanomaterialsWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2020Year of publication
- Publication date
-
2020-07-09Full publication date if available
- Authors
-
Heloise Ribeiro de Barros, Fernando López‐Gallego, Luis M. Liz‐MarzánList of authors in order
- Landing page
-
https://doi.org/10.1021/acs.biochem.0c00447Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- OA URL
-
https://zenodo.org/record/3937981Direct OA link when available
- Concepts
-
Nanomaterials, Nanotechnology, Plasmon, Surface plasmon resonance, Photothermal therapy, Plasmonic nanoparticles, Photothermal effect, Materials science, Nanoparticle, Chemistry, OptoelectronicsTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
15Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 3, 2024: 3, 2023: 2, 2022: 2, 2021: 3Per-year citation counts (last 5 years)
- References (count)
-
52Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W3040862332 |
|---|---|
| doi | https://doi.org/10.1021/acs.biochem.0c00447 |
| ids.doi | https://doi.org/10.1021/acs.biochem.0c00447 |
| ids.mag | 3040862332 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/32643921 |
| ids.openalex | https://openalex.org/W3040862332 |
| fwci | 0.87774276 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D055162 |
| mesh[0].is_major_topic | True |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Biocatalysis |
| mesh[1].qualifier_ui | Q000378 |
| mesh[1].descriptor_ui | D004798 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | metabolism |
| mesh[1].descriptor_name | Enzymes |
| mesh[2].qualifier_ui | |
| mesh[2].descriptor_ui | D008027 |
| mesh[2].is_major_topic | True |
| mesh[2].qualifier_name | |
| mesh[2].descriptor_name | Light |
| mesh[3].qualifier_ui | Q000737 |
| mesh[3].descriptor_ui | D049329 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | chemistry |
| mesh[3].descriptor_name | Nanostructures |
| mesh[4].qualifier_ui | |
| mesh[4].descriptor_ui | D036103 |
| mesh[4].is_major_topic | True |
| mesh[4].qualifier_name | |
| mesh[4].descriptor_name | Nanotechnology |
| mesh[5].qualifier_ui | |
| mesh[5].descriptor_ui | D020349 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | |
| mesh[5].descriptor_name | Surface Plasmon Resonance |
| mesh[6].qualifier_ui | |
| mesh[6].descriptor_ui | D013696 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | |
| mesh[6].descriptor_name | Temperature |
| mesh[7].qualifier_ui | |
| mesh[7].descriptor_ui | D055162 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | |
| mesh[7].descriptor_name | Biocatalysis |
| mesh[8].qualifier_ui | Q000737 |
| mesh[8].descriptor_ui | D004798 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | chemistry |
| mesh[8].descriptor_name | Enzymes |
| mesh[9].qualifier_ui | Q000378 |
| mesh[9].descriptor_ui | D004798 |
| mesh[9].is_major_topic | False |
| mesh[9].qualifier_name | metabolism |
| mesh[9].descriptor_name | Enzymes |
| mesh[10].qualifier_ui | Q000737 |
| mesh[10].descriptor_ui | D004800 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | chemistry |
| mesh[10].descriptor_name | Enzymes, Immobilized |
| mesh[11].qualifier_ui | Q000378 |
| mesh[11].descriptor_ui | D004800 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | metabolism |
| mesh[11].descriptor_name | Enzymes, Immobilized |
| mesh[12].qualifier_ui | |
| mesh[12].descriptor_ui | D008027 |
| mesh[12].is_major_topic | True |
| mesh[12].qualifier_name | |
| mesh[12].descriptor_name | Light |
| mesh[13].qualifier_ui | Q000737 |
| mesh[13].descriptor_ui | D053768 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | chemistry |
| mesh[13].descriptor_name | Metal Nanoparticles |
| mesh[14].qualifier_ui | Q000737 |
| mesh[14].descriptor_ui | D049329 |
| mesh[14].is_major_topic | True |
| mesh[14].qualifier_name | chemistry |
| mesh[14].descriptor_name | Nanostructures |
| mesh[15].qualifier_ui | |
| mesh[15].descriptor_ui | D020349 |
| mesh[15].is_major_topic | True |
| mesh[15].qualifier_name | |
| mesh[15].descriptor_name | Surface Plasmon Resonance |
| mesh[16].qualifier_ui | |
| mesh[16].descriptor_ui | D020349 |
| mesh[16].is_major_topic | True |
| mesh[16].qualifier_name | |
| mesh[16].descriptor_name | Surface Plasmon Resonance |
| mesh[17].qualifier_ui | |
| mesh[17].descriptor_ui | D008027 |
| mesh[17].is_major_topic | True |
| mesh[17].qualifier_name | |
| mesh[17].descriptor_name | Light |
| mesh[18].qualifier_ui | Q000737 |
| mesh[18].descriptor_ui | D049329 |
| mesh[18].is_major_topic | True |
| mesh[18].qualifier_name | chemistry |
| mesh[18].descriptor_name | Nanostructures |
| mesh[19].qualifier_ui | Q000737 |
| mesh[19].descriptor_ui | D004798 |
| mesh[19].is_major_topic | False |
| mesh[19].qualifier_name | chemistry |
| mesh[19].descriptor_name | Enzymes |
| mesh[20].qualifier_ui | Q000378 |
| mesh[20].descriptor_ui | D004798 |
| mesh[20].is_major_topic | False |
| mesh[20].qualifier_name | metabolism |
| mesh[20].descriptor_name | Enzymes |
| mesh[21].qualifier_ui | |
| mesh[21].descriptor_ui | D055162 |
| mesh[21].is_major_topic | False |
| mesh[21].qualifier_name | |
| mesh[21].descriptor_name | Biocatalysis |
| mesh[22].qualifier_ui | Q000737 |
| mesh[22].descriptor_ui | D004800 |
| mesh[22].is_major_topic | False |
| mesh[22].qualifier_name | chemistry |
| mesh[22].descriptor_name | Enzymes, Immobilized |
| mesh[23].qualifier_ui | Q000378 |
| mesh[23].descriptor_ui | D004800 |
| mesh[23].is_major_topic | False |
| mesh[23].qualifier_name | metabolism |
| mesh[23].descriptor_name | Enzymes, Immobilized |
| mesh[24].qualifier_ui | Q000737 |
| mesh[24].descriptor_ui | D053768 |
| mesh[24].is_major_topic | False |
| mesh[24].qualifier_name | chemistry |
| mesh[24].descriptor_name | Metal Nanoparticles |
| mesh[25].qualifier_ui | |
| mesh[25].descriptor_ui | D055162 |
| mesh[25].is_major_topic | False |
| mesh[25].qualifier_name | |
| mesh[25].descriptor_name | Biocatalysis |
| mesh[26].qualifier_ui | Q000737 |
| mesh[26].descriptor_ui | D004798 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | chemistry |
| mesh[26].descriptor_name | Enzymes |
| mesh[27].qualifier_ui | Q000378 |
| mesh[27].descriptor_ui | D004798 |
| mesh[27].is_major_topic | False |
| mesh[27].qualifier_name | metabolism |
| mesh[27].descriptor_name | Enzymes |
| mesh[28].qualifier_ui | Q000737 |
| mesh[28].descriptor_ui | D004800 |
| mesh[28].is_major_topic | False |
| mesh[28].qualifier_name | chemistry |
| mesh[28].descriptor_name | Enzymes, Immobilized |
| mesh[29].qualifier_ui | Q000378 |
| mesh[29].descriptor_ui | D004800 |
| mesh[29].is_major_topic | False |
| mesh[29].qualifier_name | metabolism |
| mesh[29].descriptor_name | Enzymes, Immobilized |
| mesh[30].qualifier_ui | |
| mesh[30].descriptor_ui | D008027 |
| mesh[30].is_major_topic | True |
| mesh[30].qualifier_name | |
| mesh[30].descriptor_name | Light |
| mesh[31].qualifier_ui | Q000737 |
| mesh[31].descriptor_ui | D053768 |
| mesh[31].is_major_topic | False |
| mesh[31].qualifier_name | chemistry |
| mesh[31].descriptor_name | Metal Nanoparticles |
| mesh[32].qualifier_ui | Q000737 |
| mesh[32].descriptor_ui | D049329 |
| mesh[32].is_major_topic | True |
| mesh[32].qualifier_name | chemistry |
| mesh[32].descriptor_name | Nanostructures |
| mesh[33].qualifier_ui | |
| mesh[33].descriptor_ui | D020349 |
| mesh[33].is_major_topic | True |
| mesh[33].qualifier_name | |
| mesh[33].descriptor_name | Surface Plasmon Resonance |
| type | article |
| title | Light-Driven Catalytic Regulation of Enzymes at the Interface with Plasmonic Nanomaterials |
| awards[0].id | https://openalex.org/G4599258179 |
| awards[0].funder_id | https://openalex.org/F4320320997 |
| awards[0].display_name | |
| awards[0].funder_award_id | FAPESP 2019/09668-0 |
| awards[0].funder_display_name | Fundação de Amparo à Pesquisa do Estado de São Paulo |
| awards[1].id | https://openalex.org/G7454323419 |
| awards[1].funder_id | https://openalex.org/F4320338335 |
| awards[1].display_name | Artificial metabolic cells for biomanufacturing of bio-based chiral fine chemicals |
| awards[1].funder_award_id | 818089 |
| awards[1].funder_display_name | H2020 European Research Council |
| awards[2].id | https://openalex.org/G5062436685 |
| awards[2].funder_id | https://openalex.org/F4320321837 |
| awards[2].display_name | |
| awards[2].funder_award_id | MDM-2017-0720 |
| awards[2].funder_display_name | Ministerio de Economía y Competitividad |
| awards[3].id | https://openalex.org/G5457132876 |
| awards[3].funder_id | https://openalex.org/F4320338335 |
| awards[3].display_name | Four-Dimensional Monitoring of Tumour Growth by Surface Enhanced Raman Scattering |
| awards[3].funder_award_id | 787510 |
| awards[3].funder_display_name | H2020 European Research Council |
| biblio.issue | 13 |
| biblio.volume | 60 |
| biblio.last_page | 998 |
| biblio.first_page | 991 |
| topics[0].id | https://openalex.org/T10404 |
| topics[0].field.id | https://openalex.org/fields/13 |
| topics[0].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[0].score | 0.9976999759674072 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/1312 |
| topics[0].subfield.display_name | Molecular Biology |
| topics[0].display_name | Enzyme Catalysis and Immobilization |
| topics[1].id | https://openalex.org/T10131 |
| topics[1].field.id | https://openalex.org/fields/25 |
| topics[1].field.display_name | Materials Science |
| topics[1].score | 0.9957000017166138 |
| topics[1].domain.id | https://openalex.org/domains/3 |
| topics[1].domain.display_name | Physical Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2504 |
| topics[1].subfield.display_name | Electronic, Optical and Magnetic Materials |
| topics[1].display_name | Gold and Silver Nanoparticles Synthesis and Applications |
| topics[2].id | https://openalex.org/T12302 |
| topics[2].field.id | https://openalex.org/fields/25 |
| topics[2].field.display_name | Materials Science |
| topics[2].score | 0.9929999709129333 |
| topics[2].domain.id | https://openalex.org/domains/3 |
| topics[2].domain.display_name | Physical Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2505 |
| topics[2].subfield.display_name | Materials Chemistry |
| topics[2].display_name | Advanced Nanomaterials in Catalysis |
| funders[0].id | https://openalex.org/F4320320997 |
| funders[0].ror | https://ror.org/02ddkpn78 |
| funders[0].display_name | Fundação de Amparo à Pesquisa do Estado de São Paulo |
| funders[1].id | https://openalex.org/F4320321837 |
| funders[1].ror | https://ror.org/034900433 |
| funders[1].display_name | Ministerio de Economía y Competitividad |
| funders[2].id | https://openalex.org/F4320322262 |
| funders[2].ror | https://ror.org/01cc3fy72 |
| funders[2].display_name | Ikerbasque, Basque Foundation for Science |
| funders[3].id | https://openalex.org/F4320338335 |
| funders[3].ror | https://ror.org/0472cxd90 |
| funders[3].display_name | H2020 European Research Council |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C138631740 |
| concepts[0].level | 2 |
| concepts[0].score | 0.8201931118965149 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q967847 |
| concepts[0].display_name | Nanomaterials |
| concepts[1].id | https://openalex.org/C171250308 |
| concepts[1].level | 1 |
| concepts[1].score | 0.7254030704498291 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q11468 |
| concepts[1].display_name | Nanotechnology |
| concepts[2].id | https://openalex.org/C110879396 |
| concepts[2].level | 2 |
| concepts[2].score | 0.6723707318305969 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q58392 |
| concepts[2].display_name | Plasmon |
| concepts[3].id | https://openalex.org/C106847996 |
| concepts[3].level | 3 |
| concepts[3].score | 0.5662923455238342 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q898756 |
| concepts[3].display_name | Surface plasmon resonance |
| concepts[4].id | https://openalex.org/C182606246 |
| concepts[4].level | 2 |
| concepts[4].score | 0.5628918409347534 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q7187926 |
| concepts[4].display_name | Photothermal therapy |
| concepts[5].id | https://openalex.org/C85255121 |
| concepts[5].level | 3 |
| concepts[5].score | 0.545077383518219 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q7201984 |
| concepts[5].display_name | Plasmonic nanoparticles |
| concepts[6].id | https://openalex.org/C2777742735 |
| concepts[6].level | 3 |
| concepts[6].score | 0.5386663675308228 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q7187921 |
| concepts[6].display_name | Photothermal effect |
| concepts[7].id | https://openalex.org/C192562407 |
| concepts[7].level | 0 |
| concepts[7].score | 0.5053711533546448 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q228736 |
| concepts[7].display_name | Materials science |
| concepts[8].id | https://openalex.org/C155672457 |
| concepts[8].level | 2 |
| concepts[8].score | 0.4481986463069916 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q61231 |
| concepts[8].display_name | Nanoparticle |
| concepts[9].id | https://openalex.org/C185592680 |
| concepts[9].level | 0 |
| concepts[9].score | 0.3800906836986542 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q2329 |
| concepts[9].display_name | Chemistry |
| concepts[10].id | https://openalex.org/C49040817 |
| concepts[10].level | 1 |
| concepts[10].score | 0.17268106341362 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q193091 |
| concepts[10].display_name | Optoelectronics |
| keywords[0].id | https://openalex.org/keywords/nanomaterials |
| keywords[0].score | 0.8201931118965149 |
| keywords[0].display_name | Nanomaterials |
| keywords[1].id | https://openalex.org/keywords/nanotechnology |
| keywords[1].score | 0.7254030704498291 |
| keywords[1].display_name | Nanotechnology |
| keywords[2].id | https://openalex.org/keywords/plasmon |
| keywords[2].score | 0.6723707318305969 |
| keywords[2].display_name | Plasmon |
| keywords[3].id | https://openalex.org/keywords/surface-plasmon-resonance |
| keywords[3].score | 0.5662923455238342 |
| keywords[3].display_name | Surface plasmon resonance |
| keywords[4].id | https://openalex.org/keywords/photothermal-therapy |
| keywords[4].score | 0.5628918409347534 |
| keywords[4].display_name | Photothermal therapy |
| keywords[5].id | https://openalex.org/keywords/plasmonic-nanoparticles |
| keywords[5].score | 0.545077383518219 |
| keywords[5].display_name | Plasmonic nanoparticles |
| keywords[6].id | https://openalex.org/keywords/photothermal-effect |
| keywords[6].score | 0.5386663675308228 |
| keywords[6].display_name | Photothermal effect |
| keywords[7].id | https://openalex.org/keywords/materials-science |
| keywords[7].score | 0.5053711533546448 |
| keywords[7].display_name | Materials science |
| keywords[8].id | https://openalex.org/keywords/nanoparticle |
| keywords[8].score | 0.4481986463069916 |
| keywords[8].display_name | Nanoparticle |
| keywords[9].id | https://openalex.org/keywords/chemistry |
| keywords[9].score | 0.3800906836986542 |
| keywords[9].display_name | Chemistry |
| keywords[10].id | https://openalex.org/keywords/optoelectronics |
| keywords[10].score | 0.17268106341362 |
| keywords[10].display_name | Optoelectronics |
| language | en |
| locations[0].id | doi:10.1021/acs.biochem.0c00447 |
| locations[0].is_oa | False |
| locations[0].source.id | https://openalex.org/S104038378 |
| locations[0].source.issn | 0006-2960, 1520-4995, 1943-295X |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 0006-2960 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Biochemistry |
| locations[0].source.host_organization | https://openalex.org/P4310320006 |
| locations[0].source.host_organization_name | American Chemical Society |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320006 |
| locations[0].source.host_organization_lineage_names | American Chemical Society |
| locations[0].license | |
| locations[0].pdf_url | |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Biochemistry |
| locations[0].landing_page_url | https://doi.org/10.1021/acs.biochem.0c00447 |
| locations[1].id | pmid:32643921 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Biochemistry |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/32643921 |
| locations[2].id | pmh:oai:zenodo.org:3937981 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S4306400562 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | True |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | Zenodo (CERN European Organization for Nuclear Research) |
| locations[2].source.host_organization | https://openalex.org/I67311998 |
| locations[2].source.host_organization_name | European Organization for Nuclear Research |
| locations[2].source.host_organization_lineage | https://openalex.org/I67311998 |
| locations[2].license | cc-by |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | info:eu-repo/semantics/article |
| locations[2].license_id | https://openalex.org/licenses/cc-by |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Biochemistry, (2020-07-09) |
| locations[2].landing_page_url | https://zenodo.org/record/3937981 |
| indexed_in | crossref, pubmed |
| authorships[0].author.id | https://openalex.org/A5060454891 |
| authorships[0].author.orcid | https://orcid.org/0000-0003-2700-7803 |
| authorships[0].author.display_name | Heloise Ribeiro de Barros |
| authorships[0].countries | BR, ES |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I17974374 |
| authorships[0].affiliations[0].raw_affiliation_string | Institute of Chemistry, University of São Paulo, Av. Prof. Lineu Prestes, 748, Vila Universitária, 05508-000 São Paulo, São Paulo Brazil |
| authorships[0].affiliations[1].institution_ids | https://openalex.org/I4210087187 |
| authorships[0].affiliations[1].raw_affiliation_string | CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Paseo de Miramón 182, 20014 Donostia, San Sebastián, Spain |
| authorships[0].institutions[0].id | https://openalex.org/I17974374 |
| authorships[0].institutions[0].ror | https://ror.org/036rp1748 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I17974374 |
| authorships[0].institutions[0].country_code | BR |
| authorships[0].institutions[0].display_name | Universidade de São Paulo |
| authorships[0].institutions[1].id | https://openalex.org/I4210087187 |
| authorships[0].institutions[1].ror | https://ror.org/004g03602 |
| authorships[0].institutions[1].type | nonprofit |
| authorships[0].institutions[1].lineage | https://openalex.org/I4210087187 |
| authorships[0].institutions[1].country_code | ES |
| authorships[0].institutions[1].display_name | CIC biomaGUNE |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Heloise Ribeiro de Barros |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Paseo de Miramón 182, 20014 Donostia, San Sebastián, Spain, Institute of Chemistry, University of São Paulo, Av. Prof. Lineu Prestes, 748, Vila Universitária, 05508-000 São Paulo, São Paulo Brazil |
| authorships[1].author.id | https://openalex.org/A5033368136 |
| authorships[1].author.orcid | https://orcid.org/0000-0003-0031-1880 |
| authorships[1].author.display_name | Fernando López‐Gallego |
| authorships[1].countries | ES |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I110594554 |
| authorships[1].affiliations[0].raw_affiliation_string | IKERBASQUE, Basque Foundation for Science, 48013 Bilbao, Spain |
| authorships[1].affiliations[1].institution_ids | https://openalex.org/I4210087187 |
| authorships[1].affiliations[1].raw_affiliation_string | CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Paseo de Miramón 182, 20014 Donostia, San Sebastián, Spain |
| authorships[1].institutions[0].id | https://openalex.org/I4210087187 |
| authorships[1].institutions[0].ror | https://ror.org/004g03602 |
| authorships[1].institutions[0].type | nonprofit |
| authorships[1].institutions[0].lineage | https://openalex.org/I4210087187 |
| authorships[1].institutions[0].country_code | ES |
| authorships[1].institutions[0].display_name | CIC biomaGUNE |
| authorships[1].institutions[1].id | https://openalex.org/I110594554 |
| authorships[1].institutions[1].ror | https://ror.org/01cc3fy72 |
| authorships[1].institutions[1].type | other |
| authorships[1].institutions[1].lineage | https://openalex.org/I110594554 |
| authorships[1].institutions[1].country_code | ES |
| authorships[1].institutions[1].display_name | Ikerbasque |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Fernando López-Gallego |
| authorships[1].is_corresponding | True |
| authorships[1].raw_affiliation_strings | CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Paseo de Miramón 182, 20014 Donostia, San Sebastián, Spain, IKERBASQUE, Basque Foundation for Science, 48013 Bilbao, Spain |
| authorships[2].author.id | https://openalex.org/A5064970528 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-6647-1353 |
| authorships[2].author.display_name | Luis M. Liz‐Marzán |
| authorships[2].countries | ES |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I4210105141, https://openalex.org/I4210115082 |
| authorships[2].affiliations[0].raw_affiliation_string | Centro de Investigación Biomédica en Red, Bioingenierı́a, Biomateriales y Nanomedicina (CIBER-BBN), Paseo de Miramón 182, 20014 Donostia, San Sebastián, Spain |
| authorships[2].affiliations[1].institution_ids | https://openalex.org/I110594554 |
| authorships[2].affiliations[1].raw_affiliation_string | IKERBASQUE, Basque Foundation for Science, 48013 Bilbao, Spain |
| authorships[2].affiliations[2].institution_ids | https://openalex.org/I4210087187 |
| authorships[2].affiliations[2].raw_affiliation_string | CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Paseo de Miramón 182, 20014 Donostia, San Sebastián, Spain |
| authorships[2].institutions[0].id | https://openalex.org/I4210105141 |
| authorships[2].institutions[0].ror | https://ror.org/01gm5f004 |
| authorships[2].institutions[0].type | other |
| authorships[2].institutions[0].lineage | https://openalex.org/I4210105141 |
| authorships[2].institutions[0].country_code | ES |
| authorships[2].institutions[0].display_name | Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine |
| authorships[2].institutions[1].id | https://openalex.org/I4210087187 |
| authorships[2].institutions[1].ror | https://ror.org/004g03602 |
| authorships[2].institutions[1].type | nonprofit |
| authorships[2].institutions[1].lineage | https://openalex.org/I4210087187 |
| authorships[2].institutions[1].country_code | ES |
| authorships[2].institutions[1].display_name | CIC biomaGUNE |
| authorships[2].institutions[2].id | https://openalex.org/I4210115082 |
| authorships[2].institutions[2].ror | https://ror.org/02g87qh62 |
| authorships[2].institutions[2].type | facility |
| authorships[2].institutions[2].lineage | https://openalex.org/I2801357902, https://openalex.org/I4210115082, https://openalex.org/I4387152914 |
| authorships[2].institutions[2].country_code | ES |
| authorships[2].institutions[2].display_name | Centro de Investigación Biomédica en Red |
| authorships[2].institutions[3].id | https://openalex.org/I110594554 |
| authorships[2].institutions[3].ror | https://ror.org/01cc3fy72 |
| authorships[2].institutions[3].type | other |
| authorships[2].institutions[3].lineage | https://openalex.org/I110594554 |
| authorships[2].institutions[3].country_code | ES |
| authorships[2].institutions[3].display_name | Ikerbasque |
| authorships[2].author_position | last |
| authorships[2].raw_author_name | Luis M. Liz-Marzán |
| authorships[2].is_corresponding | True |
| authorships[2].raw_affiliation_strings | CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Paseo de Miramón 182, 20014 Donostia, San Sebastián, Spain, Centro de Investigación Biomédica en Red, Bioingenierı́a, Biomateriales y Nanomedicina (CIBER-BBN), Paseo de Miramón 182, 20014 Donostia, San Sebastián, Spain, IKERBASQUE, Basque Foundation for Science, 48013 Bilbao, Spain |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://zenodo.org/record/3937981 |
| open_access.oa_status | green |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Light-Driven Catalytic Regulation of Enzymes at the Interface with Plasmonic Nanomaterials |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10404 |
| primary_topic.field.id | https://openalex.org/fields/13 |
| primary_topic.field.display_name | Biochemistry, Genetics and Molecular Biology |
| primary_topic.score | 0.9976999759674072 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/1312 |
| primary_topic.subfield.display_name | Molecular Biology |
| primary_topic.display_name | Enzyme Catalysis and Immobilization |
| related_works | https://openalex.org/W3166872181, https://openalex.org/W4244396274, https://openalex.org/W1999386415, https://openalex.org/W3046719367, https://openalex.org/W2125027697, https://openalex.org/W4280492383, https://openalex.org/W4393254148, https://openalex.org/W4293002997, https://openalex.org/W3110819540, https://openalex.org/W2780070282 |
| cited_by_count | 15 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 3 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 3 |
| counts_by_year[2].year | 2023 |
| counts_by_year[2].cited_by_count | 2 |
| counts_by_year[3].year | 2022 |
| counts_by_year[3].cited_by_count | 2 |
| counts_by_year[4].year | 2021 |
| counts_by_year[4].cited_by_count | 3 |
| counts_by_year[5].year | 2020 |
| counts_by_year[5].cited_by_count | 2 |
| locations_count | 3 |
| best_oa_location.id | pmh:oai:zenodo.org:3937981 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S4306400562 |
| best_oa_location.source.issn | |
| best_oa_location.source.type | repository |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | |
| best_oa_location.source.is_core | False |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | Zenodo (CERN European Organization for Nuclear Research) |
| best_oa_location.source.host_organization | https://openalex.org/I67311998 |
| best_oa_location.source.host_organization_name | European Organization for Nuclear Research |
| best_oa_location.source.host_organization_lineage | https://openalex.org/I67311998 |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | |
| best_oa_location.version | submittedVersion |
| best_oa_location.raw_type | info:eu-repo/semantics/article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | False |
| best_oa_location.is_published | False |
| best_oa_location.raw_source_name | Biochemistry, (2020-07-09) |
| best_oa_location.landing_page_url | https://zenodo.org/record/3937981 |
| primary_location.id | doi:10.1021/acs.biochem.0c00447 |
| primary_location.is_oa | False |
| primary_location.source.id | https://openalex.org/S104038378 |
| primary_location.source.issn | 0006-2960, 1520-4995, 1943-295X |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 0006-2960 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Biochemistry |
| primary_location.source.host_organization | https://openalex.org/P4310320006 |
| primary_location.source.host_organization_name | American Chemical Society |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320006 |
| primary_location.source.host_organization_lineage_names | American Chemical Society |
| primary_location.license | |
| primary_location.pdf_url | |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Biochemistry |
| primary_location.landing_page_url | https://doi.org/10.1021/acs.biochem.0c00447 |
| publication_date | 2020-07-09 |
| publication_year | 2020 |
| referenced_works | https://openalex.org/W2168846334, https://openalex.org/W2807550794, https://openalex.org/W2064030623, https://openalex.org/W2079202953, https://openalex.org/W2049753441, https://openalex.org/W1993331221, https://openalex.org/W2012484827, https://openalex.org/W2981052344, https://openalex.org/W2734541716, https://openalex.org/W2783550887, https://openalex.org/W2981562835, https://openalex.org/W2584662392, https://openalex.org/W2734883636, https://openalex.org/W2974298821, https://openalex.org/W2553847684, https://openalex.org/W2029652729, https://openalex.org/W2920795453, https://openalex.org/W2950247537, https://openalex.org/W2125994231, https://openalex.org/W2076719191, https://openalex.org/W2314579617, https://openalex.org/W2944820767, https://openalex.org/W2964740336, https://openalex.org/W2570448438, https://openalex.org/W4253847203, https://openalex.org/W93881162, https://openalex.org/W2899638604, https://openalex.org/W2195807401, https://openalex.org/W2121913115, https://openalex.org/W2342158251, https://openalex.org/W2613083880, https://openalex.org/W2616173417, https://openalex.org/W2595977605, https://openalex.org/W2165075822, https://openalex.org/W2914235984, https://openalex.org/W3021459197, https://openalex.org/W2936378241, https://openalex.org/W2804699682, https://openalex.org/W2152940535, https://openalex.org/W2908411885, https://openalex.org/W2026687720, https://openalex.org/W2161989523, https://openalex.org/W2612860585, https://openalex.org/W2591586996, https://openalex.org/W2750794414, https://openalex.org/W2074587918, https://openalex.org/W2974892258, https://openalex.org/W2516777835, https://openalex.org/W1777575432, https://openalex.org/W2996948262, https://openalex.org/W2768392336, https://openalex.org/W2809414926 |
| referenced_works_count | 52 |
| abstract_inverted_index.a | 20, 85 |
| abstract_inverted_index.As | 84 |
| abstract_inverted_index.In | 126 |
| abstract_inverted_index.To | 96 |
| abstract_inverted_index.an | 64 |
| abstract_inverted_index.at | 46 |
| abstract_inverted_index.be | 40, 61, 124 |
| abstract_inverted_index.by | 76 |
| abstract_inverted_index.in | 187, 200 |
| abstract_inverted_index.is | 3, 176 |
| abstract_inverted_index.of | 1, 27, 66, 89, 110, 114, 137, 153, 157, 163, 169, 190 |
| abstract_inverted_index.or | 79 |
| abstract_inverted_index.to | 23, 42, 63, 73, 100, 140, 160, 185 |
| abstract_inverted_index.we | 129, 148, 180 |
| abstract_inverted_index.and | 9, 102, 118, 196, 204 |
| abstract_inverted_index.but | 71 |
| abstract_inverted_index.can | 39, 55 |
| abstract_inverted_index.for | 166 |
| abstract_inverted_index.hot | 80 |
| abstract_inverted_index.its | 178 |
| abstract_inverted_index.may | 60 |
| abstract_inverted_index.the | 25, 47, 90, 107, 111, 115, 135, 151, 155, 161, 182, 188 |
| abstract_inverted_index.use | 136, 156 |
| abstract_inverted_index.LSPR | 145 |
| abstract_inverted_index.also | 72, 149 |
| abstract_inverted_index.must | 123 |
| abstract_inverted_index.that | 133 |
| abstract_inverted_index.this | 127, 174 |
| abstract_inverted_index.tune | 24 |
| abstract_inverted_index.upon | 50 |
| abstract_inverted_index.used | 41 |
| abstract_inverted_index.great | 21 |
| abstract_inverted_index.light | 51, 54, 87 |
| abstract_inverted_index.local | 67 |
| abstract_inverted_index.novel | 191 |
| abstract_inverted_index.offer | 19 |
| abstract_inverted_index.their | 14, 30, 198 |
| abstract_inverted_index.these | 98 |
| abstract_inverted_index.which | 59 |
| abstract_inverted_index.(LSPR) | 38 |
| abstract_inverted_index.enzyme | 94, 105, 142 |
| abstract_inverted_index.finely | 101 |
| abstract_inverted_index.highly | 4 |
| abstract_inverted_index.light, | 117 |
| abstract_inverted_index.living | 177 |
| abstract_inverted_index.modify | 43 |
| abstract_inverted_index.toward | 6 |
| abstract_inverted_index.advance | 186 |
| abstract_inverted_index.affects | 93 |
| abstract_inverted_index.applied | 202 |
| abstract_inverted_index.concept | 175 |
| abstract_inverted_index.control | 141 |
| abstract_inverted_index.discuss | 130 |
| abstract_inverted_index.effects | 74, 99 |
| abstract_inverted_index.enzymes | 2, 28 |
| abstract_inverted_index.explore | 197 |
| abstract_inverted_index.harness | 97 |
| abstract_inverted_index.optical | 32 |
| abstract_inverted_index.overall | 15 |
| abstract_inverted_index.plasmon | 36 |
| abstract_inverted_index.promote | 56 |
| abstract_inverted_index.related | 62 |
| abstract_inverted_index.surface | 35 |
| abstract_inverted_index.systems | 165 |
| abstract_inverted_index.thereby | 12 |
| abstract_inverted_index.through | 29, 144 |
| abstract_inverted_index.Although | 173 |
| abstract_inverted_index.Finally, | 147 |
| abstract_inverted_index.Incident | 53 |
| abstract_inverted_index.chemical | 44 |
| abstract_inverted_index.effects) | 70 |
| abstract_inverted_index.examples | 132 |
| abstract_inverted_index.features | 109 |
| abstract_inverted_index.function | 143 |
| abstract_inverted_index.hotspots | 78 |
| abstract_inverted_index.incident | 116 |
| abstract_inverted_index.increase | 65 |
| abstract_inverted_index.infancy, | 179 |
| abstract_inverted_index.regulate | 104 |
| abstract_inverted_index.relevant | 5, 131 |
| abstract_inverted_index.remotely | 103 |
| abstract_inverted_index.stepwise | 10 |
| abstract_inverted_index.surface, | 49 |
| abstract_inverted_index.Localized | 34 |
| abstract_inverted_index.Plasmonic | 17 |
| abstract_inverted_index.activity, | 106 |
| abstract_inverted_index.cell-free | 8, 170 |
| abstract_inverted_index.community | 184 |
| abstract_inverted_index.effects). | 83 |
| abstract_inverted_index.electrons | 81 |
| abstract_inverted_index.encourage | 181 |
| abstract_inverted_index.energetic | 57 |
| abstract_inverted_index.expanding | 154 |
| abstract_inverted_index.generated | 77 |
| abstract_inverted_index.governing | 120 |
| abstract_inverted_index.highlight | 150 |
| abstract_inverted_index.interface | 92 |
| abstract_inverted_index.molecular | 121 |
| abstract_inverted_index.pathways. | 172 |
| abstract_inverted_index.plasmonic | 138, 158, 194 |
| abstract_inverted_index.triggered | 75 |
| abstract_inverted_index.Regulation | 0 |
| abstract_inverted_index.illustrate | 134 |
| abstract_inverted_index.importance | 152 |
| abstract_inverted_index.maximizing | 13 |
| abstract_inverted_index.optimized. | 125 |
| abstract_inverted_index.parameters | 119 |
| abstract_inverted_index.processes, | 58 |
| abstract_inverted_index.properties | 113 |
| abstract_inverted_index.regulation | 168 |
| abstract_inverted_index.remarkable | 31 |
| abstract_inverted_index.resonances | 37 |
| abstract_inverted_index.scientific | 183 |
| abstract_inverted_index.application | 199 |
| abstract_inverted_index.biosensing, | 201 |
| abstract_inverted_index.development | 189 |
| abstract_inverted_index.excitation. | 146 |
| abstract_inverted_index.irradiation | 88 |
| abstract_inverted_index.multienzyme | 164 |
| abstract_inverted_index.opportunity | 22 |
| abstract_inverted_index.properties. | 33 |
| abstract_inverted_index.temperature | 68 |
| abstract_inverted_index.Perspective, | 128 |
| abstract_inverted_index.biocatalytic | 193 |
| abstract_inverted_index.biomedicine. | 205 |
| abstract_inverted_index.biosynthetic | 171 |
| abstract_inverted_index.consequence, | 86 |
| abstract_inverted_index.interactions | 122 |
| abstract_inverted_index.irradiation. | 52 |
| abstract_inverted_index.light-driven | 167 |
| abstract_inverted_index.performance. | 16 |
| abstract_inverted_index.(photothermal | 69 |
| abstract_inverted_index.biocatalysis, | 203 |
| abstract_inverted_index.functionality | 26 |
| abstract_inverted_index.nanomaterial, | 112 |
| abstract_inverted_index.nanomaterials | 18, 159 |
| abstract_inverted_index.nanoparticles | 139 |
| abstract_inverted_index.orchestrating | 7 |
| abstract_inverted_index.functionality. | 95 |
| abstract_inverted_index.immobilization | 162 |
| abstract_inverted_index.nanoconjugates | 195 |
| abstract_inverted_index.nanomaterial's | 48 |
| abstract_inverted_index.physicochemical | 108 |
| abstract_inverted_index.transformations | 45 |
| abstract_inverted_index.(photoelectronic | 82 |
| abstract_inverted_index.light-controlled | 192 |
| abstract_inverted_index.biotransformations, | 11 |
| abstract_inverted_index.protein-nanomaterial | 91 |
| cited_by_percentile_year.max | 97 |
| cited_by_percentile_year.min | 94 |
| corresponding_author_ids | https://openalex.org/A5064970528, https://openalex.org/A5033368136 |
| countries_distinct_count | 2 |
| institutions_distinct_count | 3 |
| corresponding_institution_ids | https://openalex.org/I110594554, https://openalex.org/I4210087187, https://openalex.org/I4210105141, https://openalex.org/I4210115082 |
| citation_normalized_percentile.value | 0.71245929 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |