Limitations in Achieving Glycemic Targets from CGM data and Persistence of Severe Hypoglycemia in Adults with Type 1 Diabetes Regardless of Insulin Delivery Method Article Swipe

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Lori M. Laffel , Jennifer L. Sherr , Jingwen Liu , Wendy A. Wolf , Jeoffrey Bispham , KATHERINE S.M. CHAPMAN , Daniel A. Finan , Lina Titievsky , Tina Liu , Kaitlin Hagan , Jason L. Gaglia , Keval Chandarana , Jeremy Pettus , Richard M. Bergenstal ·

YOU? · · 2024 · Open Access · · DOI: https://doi.org/10.2337/figshare.27637839

ObjectivesWe captured CGM metrics from a large, online survey of adults with type 1 diabetes to determine how glycemic outcomes varied by insulin delivery form.Research Design and Methods Adults with type 1 diabetes from the T1D Exchange Registry/online communities completed the survey and contributed up to 1-year of retrospective CGM data. Self-reported glycemic outcomes and CGM measures were described overall and by insulin delivery method.ResultsThe 926 participants completed the survey and provided CGM data. The mean age was 41.9 (standard deviation, 15.7) years and 50.8% reported using automated insulin delivery (AID). While AID users spent more time in range, 27.9% did not achieve time in range targets, 15.5% reported having severe hypoglycemic events (SHEs), and 16.0% had CGM-detected level 2 hypoglycemic events.Conclusion Despite use of diabetes technologies, many individuals are unable to achieve glycemic targets and experience severe hypoglycemia, highlighting the need for novel treatments.

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Glycemic Hypoglycemia Insulin Medicine Insulin delivery Type 1 diabetes Diabetes mellitus Type 2 diabetes Internal medicine Endocrinology

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Type: preprint
Language: en
Landing Page: https://doi.org/10.2337/figshare.27637839
OA Status: gold
Related Works: 10
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DOI: https://doi.org/10.2337/figshare.27637839

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Title: Limitations in Achieving Glycemic Targets from CGM data and Persistence of Severe Hypoglycemia in Adults with Type 1 Diabetes Regardless of Insulin Delivery Method

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Type: preprint

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Language: en

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Publication year: 2024

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Publication date: 2024-12-19

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Authors: Lori M. Laffel, Jennifer L. Sherr, Jingwen Liu, Wendy A. Wolf, Jeoffrey Bispham, KATHERINE S.M. CHAPMAN, Daniel A. Finan, Lina Titievsky, Tina Liu, Kaitlin Hagan, Jason L. Gaglia, Keval Chandarana, Jeremy Pettus, Richard M. Bergenstal

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Landing page: https://doi.org/10.2337/figshare.27637839

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Concepts: Glycemic, Hypoglycemia, Insulin, Medicine, Insulin delivery, Type 1 diabetes, Diabetes mellitus, Type 2 diabetes, Internal medicine, Endocrinology

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