Liver disease trends in the Asia-Pacific region for the next 50 years Article Swipe

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Shuichiro Shiina , Javkhlan Maikhuu , Deng Qing , Terguunbileg Batsaikhan , Lariza Marie Canseco , Maki Tobari , Hitoshi Maruyama , Hiroaki Nagamatsu , Diana Alcantara‐Payawal , Rino Alvani Gani , Yi‐Hsiang Huang , Tawesak Tanwandee , Giovanni Galati , Yoon Jun Kim ·

YOU? · · 2025 · Open Access · · DOI: https://doi.org/10.3350/cmh.2025.0043

Liver disease has emerged as a critical and escalating public health concern worldwide, with the Asia-Pacific region at the forefront of this challenge due to its vast population and diverse socioeconomic landscape. Over the coming five decades, this region will experience profound changes in liver disease patterns, shaped by rapid urbanization, lifestyle modifications, advancements in medical technologies, and evolving public health strategies. This article offers an in-depth analysis of six transformative areas defining the trajectory of liver disease in the region. First, it highlights the alarming rise of metabolic dysfunction-associated fatty liver disease and metabolic dysfunction-associated steatohepatitis, diseases driven by modern lifestyle factors and inherent metabolic susceptibilities. Concurrently, it celebrates the declining burden of viral hepatitis, underscoring the success of sustained public health interventions. However, new challenges are emerging, such as the growing impact of environmental and occupational exposures on liver health. Breakthroughs in genomic and epigenetic research promise to advance precision medicine, offering targeted therapeutic solutions. Additionally, the integration of artificial intelligence, big data, and telemedicine is poised to revolutionize liver disease management, improving accessibility and personalized care. Finally, the article emphasizes the critical role of robust health policies, preventive strategies, and cross-border collaboration in shaping a healthier future. By synthesizing these insights, the study aims to guide innovative and effective responses to the evolving liver disease landscape in the Asia-Pacific region.

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Liver disease Disease Medicine Geography Internal medicine

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Type: review
Language: en
Landing Page: https://doi.org/10.3350/cmh.2025.0043
PDF: https://www.e-cmh.org/upload/pdf/cmh-2025-0043.pdf
OA Status: gold
Cited By: 3
References: 58
Related Works: 10
OpenAlex ID: https://openalex.org/W4408130283

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DOI: https://doi.org/10.3350/cmh.2025.0043

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Title: Liver disease trends in the Asia-Pacific region for the next 50 years

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Type: review

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Language: en

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Publication year: 2025

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Publication date: 2025-03-04

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Authors: Shuichiro Shiina, Javkhlan Maikhuu, Deng Qing, Terguunbileg Batsaikhan, Lariza Marie Canseco, Maki Tobari, Hitoshi Maruyama, Hiroaki Nagamatsu, Diana Alcantara‐Payawal, Rino Alvani Gani, Yi‐Hsiang Huang, Tawesak Tanwandee, Giovanni Galati, Yoon Jun Kim

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Landing page: https://doi.org/10.3350/cmh.2025.0043

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PDF URL: https://www.e-cmh.org/upload/pdf/cmh-2025-0043.pdf

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Open access: Yes

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OA status: gold

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OA URL: https://www.e-cmh.org/upload/pdf/cmh-2025-0043.pdf

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Concepts: Liver disease, Disease, Medicine, Geography, Internal medicine

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Cited by: 3

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