Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: Surveillance Report 4 Article Swipe
Roger Chou
,
Jesse Wagner
,
Azrah Y. Ahmed
,
Benjamin J. Morasco
,
Devan Kansagara
,
Shelley Selph
,
Rebecca Holmes
,
Rongwei Fu
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.23970/ahrqepccannabissurveillance4
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.23970/ahrqepccannabissurveillance4
Overall, based on reviewed evidence, in patients with chronic (mainly neuropathic) pain with short-term treatment (4 weeks to <6 months):• Comparable THC to CBD ratio oral spray is probably associated with small improvements in pain severity and function.There may be a large increased risk of dizziness and sedation, and a moderate increased risk of nausea.• Synthetic THC (high THC to CBD ratio) may be associated with moderate improvement in pain severity but with increased risk of sedation, and potential increased risk of nausea.Synthetic THC is probably associated with a large increased risk of dizziness.• Extracted whole-plant high THC to CBD ratio products may be associated with large increases in risk of withdrawal due to adverse events and dizziness.• Evidence on whole-plant cannabis, low THC to CBD ratio products (topical or oral CBD), other cannabinoids (cannabidivarin), and comparisons with other active interventions or between different cannabis-related products (one new observational study) was insufficient to draw conclusions.• Other key adverse event outcomes (i.e., psychosis, cannabis use disorder, cognitive deficits) and outcomes on the impact on opioid use were not reported.• No evidence on other plant-based compounds, such as kratom, met criteria for this review.Table 2 presents the conclusions from the systematic review, findings from ongoing literature surveillance, and an assessment of new studies on conclusions.Table 2. Assessment of systematic review conclusions
Related Topics
Concepts
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Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: Surveillance Report 4Work title
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reportOpenAlex work type
- Language
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enPrimary language
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2022Year of publication
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2022-06-01Full publication date if available
- Authors
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Roger Chou, Jesse Wagner, Azrah Y. Ahmed, Benjamin J. Morasco, Devan Kansagara, Shelley Selph, Rebecca Holmes, Rongwei FuList of authors in order
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https://doi.org/10.23970/ahrqepccannabissurveillance4Publisher landing page
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https://effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/surveillance-report-1-cannabis-2022-update.pdfDirect link to full text PDF
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goldOpen access status per OpenAlex
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https://effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/surveillance-report-1-cannabis-2022-update.pdfDirect OA link when available
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Chronic pain, Cannabis, Medicine, PsychiatryTop concepts (fields/topics) attached by OpenAlex
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| abstract_inverted_index.cannabis | 162 |
| abstract_inverted_index.criteria | 188 |
| abstract_inverted_index.evidence | 179 |
| abstract_inverted_index.findings | 200 |
| abstract_inverted_index.moderate | 50, 66 |
| abstract_inverted_index.outcomes | 159, 168 |
| abstract_inverted_index.patients | 6 |
| abstract_inverted_index.presents | 193 |
| abstract_inverted_index.probably | 28, 85 |
| abstract_inverted_index.products | 101, 127, 145 |
| abstract_inverted_index.reviewed | 3 |
| abstract_inverted_index.severity | 35, 70 |
| abstract_inverted_index.Extracted | 94 |
| abstract_inverted_index.Synthetic | 55 |
| abstract_inverted_index.cannabis, | 121 |
| abstract_inverted_index.cognitive | 165 |
| abstract_inverted_index.deficits) | 166 |
| abstract_inverted_index.different | 143 |
| abstract_inverted_index.disorder, | 164 |
| abstract_inverted_index.dizziness | 45 |
| abstract_inverted_index.evidence, | 4 |
| abstract_inverted_index.increased | 42, 51, 73, 79, 90 |
| abstract_inverted_index.increases | 107 |
| abstract_inverted_index.potential | 78 |
| abstract_inverted_index.sedation, | 47, 76 |
| abstract_inverted_index.treatment | 14 |
| abstract_inverted_index.Assessment | 214 |
| abstract_inverted_index.Comparable | 20 |
| abstract_inverted_index.assessment | 207 |
| abstract_inverted_index.associated | 29, 64, 86, 104 |
| abstract_inverted_index.compounds, | 183 |
| abstract_inverted_index.literature | 203 |
| abstract_inverted_index.nausea.• | 54 |
| abstract_inverted_index.psychosis, | 161 |
| abstract_inverted_index.short-term | 13 |
| abstract_inverted_index.systematic | 198, 216 |
| abstract_inverted_index.withdrawal | 111 |
| abstract_inverted_index.comparisons | 136 |
| abstract_inverted_index.conclusions | 195, 218 |
| abstract_inverted_index.improvement | 67 |
| abstract_inverted_index.months):• | 19 |
| abstract_inverted_index.plant-based | 182 |
| abstract_inverted_index.whole-plant | 95, 120 |
| abstract_inverted_index.cannabinoids | 133 |
| abstract_inverted_index.improvements | 32 |
| abstract_inverted_index.insufficient | 151 |
| abstract_inverted_index.neuropathic) | 10 |
| abstract_inverted_index.reported.• | 177 |
| abstract_inverted_index.review.Table | 191 |
| abstract_inverted_index.dizziness.• | 93, 117 |
| abstract_inverted_index.interventions | 140 |
| abstract_inverted_index.observational | 148 |
| abstract_inverted_index.surveillance, | 204 |
| abstract_inverted_index.function.There | 37 |
| abstract_inverted_index.conclusions.• | 154 |
| abstract_inverted_index.cannabis-related | 144 |
| abstract_inverted_index.nausea.Synthetic | 82 |
| abstract_inverted_index.(cannabidivarin), | 134 |
| abstract_inverted_index.conclusions.Table | 212 |
| cited_by_percentile_year | |
| countries_distinct_count | 0 |
| institutions_distinct_count | 8 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.7799999713897705 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile |