Long-term outcomes of the largest (29) Epic Supra aortic valve bioprosthesis: comparing recommended with upsizing implantation Article Swipe
Murat Mukharyamov
,
Hristo Kirov
,
Maria Golovina
,
Túlio Caldonazo
,
Torsten Doenst
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1093/icvts/ivaf050
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1093/icvts/ivaf050
OBJECTIVES To investigate outcomes of aortic valve replacement with the largest available Epic Supra bioprosthesis (size 29). METHODS We reviewed all patients who received an Epic Supra bioprosthesis between 2011 and 2023 and selected all 29 size prostheses that were implanted either into patients with an aortic annulus of at least 29 mm (sizing as recommended by the manufacturer) or into patients with smaller annuli (upsizing). Short- and long-term results were assessed. Propensity score matching was employed to improve comparability between groups. Kaplan–Meier and log-rank tests were performed to compare survival. RESULTS Epic Supra bioprostheses were implanted into 1845 patients between 2011 and 2023. Mean age was 69.7 (11.2) years and 79.2% were male. Size 29 was implanted in 360 patients (mean age 68 (8.9) years), and 97.2% were male. EuroScore II was 5.1 (1.3; 6.6). One quarter of cases were performed via parasternal minithoracotomy. Mortality at 30 days was 2.8%, with no significant differences. Need for re-exploration was 3.3% and permanent pacemaker implantation was 4.7% (no statistically significant differences). Longest follow-up was 10 years with a mean of 50 (41) months. Mean prosthetic pressure gradients were 11.3 (16.7) mmHg and aortic valve reoperations/interventions were required in 5 patients (1.4%), all due to infective endocarditis. CONCLUSIONS This is the largest experience of Epic Supra 29 implantation worldwide. Our results illustrate exemplary clinical and haemodynamic performance. In addition, the 29 size prosthesis can safely be implanted into patients with smaller than 29 mm annulus, which may improve future valve-in-valve options.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/icvts/ivaf050
- https://academic.oup.com/icvts/advance-article-pdf/doi/10.1093/icvts/ivaf050/62298137/ivaf050.pdf
- OA Status
- diamond
- References
- 23
- Related Works
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- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4408217894Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1093/icvts/ivaf050Digital Object Identifier
- Title
-
Long-term outcomes of the largest (29) Epic Supra aortic valve bioprosthesis: comparing recommended with upsizing implantationWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-03-05Full publication date if available
- Authors
-
Murat Mukharyamov, Hristo Kirov, Maria Golovina, Túlio Caldonazo, Torsten DoenstList of authors in order
- Landing page
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https://doi.org/10.1093/icvts/ivaf050Publisher landing page
- PDF URL
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https://academic.oup.com/icvts/advance-article-pdf/doi/10.1093/icvts/ivaf050/62298137/ivaf050.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
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-
diamondOpen access status per OpenAlex
- OA URL
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https://academic.oup.com/icvts/advance-article-pdf/doi/10.1093/icvts/ivaf050/62298137/ivaf050.pdfDirect OA link when available
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EPIC, Term (time), Medicine, Cardiology, Internal medicine, Physics, Art, Literature, Quantum mechanicsTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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23Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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