Longer term effectiveness of inpatient multidisciplinary rehabilitation on health-related quality of life in MS patients: a pragmatic randomized controlled trial – The Danish MS Hospitals Rehabilitation Study Article Swipe
Finn Boesen
,
Michael Nørgaard
,
Philipp Trénel
,
Peter Vestergaard Rasmussen
,
Thor Petersen
,
Brita Løvendahl
,
Jan Sørensen
·
YOU?
·
· 2017
· Open Access
·
· DOI: https://doi.org/10.1177/1352458517735188
YOU?
·
· 2017
· Open Access
·
· DOI: https://doi.org/10.1177/1352458517735188
Background: There is insufficient evidence to support the effectiveness of multidisciplinary rehabilitation on the health-related quality of life (HRQoL) of MS patients. Objectives: To evaluate the longer term effectiveness of inpatient multidisciplinary rehabilitation on the HRQoL of MS patients. Methods: The study was a two-hospital, pragmatic, randomized controlled trial with a 6-month follow-up. Patients aged 18–65 years with MS and Expanded Disability Status Scale scores ≤7.5 were randomly assigned (1:1) to 4 weeks of inpatient multidisciplinary rehabilitation (20 days of scheduled rehabilitation) or 6 months on a wait list. The outcome measures were Functional Assessment in Multiple Sclerosis (FAMS), Multiple Sclerosis Impact Scale-29 (MSIS-29), EQ-5D-5L and 15D. Results: We randomized 213 patients to the wait-list control group and 214 patients to the treatment group. Trends in favour of the treatment group were observed across all measures. However, the difference was significant in only two of the six measures. The treatment effect was −2.7 (95% CI: −5.6 to (−0.1)), p = 0.046) for the MSIS-29 Psychological and 0.017 (95% CI: 0.005–0.030, p = 0.008) for the 15D. FAMS, which we used to calculate the sample size, was not significant. Conclusion: The results indicated that inpatient multidisciplinary rehabilitation is effective in improving the HRQoL of MS patients after 6 months.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1177/1352458517735188
- https://journals.sagepub.com/doi/pdf/10.1177/1352458517735188
- OA Status
- hybrid
- Cited By
- 40
- References
- 30
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2762458405
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2762458405Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1177/1352458517735188Digital Object Identifier
- Title
-
Longer term effectiveness of inpatient multidisciplinary rehabilitation on health-related quality of life in MS patients: a pragmatic randomized controlled trial – The Danish MS Hospitals Rehabilitation StudyWork title
- Type
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articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2017Year of publication
- Publication date
-
2017-10-06Full publication date if available
- Authors
-
Finn Boesen, Michael Nørgaard, Philipp Trénel, Peter Vestergaard Rasmussen, Thor Petersen, Brita Løvendahl, Jan SørensenList of authors in order
- Landing page
-
https://doi.org/10.1177/1352458517735188Publisher landing page
- PDF URL
-
https://journals.sagepub.com/doi/pdf/10.1177/1352458517735188Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
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https://journals.sagepub.com/doi/pdf/10.1177/1352458517735188Direct OA link when available
- Concepts
-
Medicine, Rehabilitation, Randomized controlled trial, Quality of life (healthcare), Physical therapy, Multidisciplinary approach, Danish, Multiple sclerosis, Surgery, Psychiatry, Nursing, Social science, Sociology, Philosophy, LinguisticsTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
40Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 4, 2024: 6, 2023: 4, 2022: 8, 2021: 4Per-year citation counts (last 5 years)
- References (count)
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30Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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