<p>The Impact of Childhood Trauma on Developing Bipolar Disorder: Current Understanding and Ensuring Continued Progress</p> Article Swipe
Yann Quidé
,
Leonardo Tozzi
,
Mark Corcoran
,
Dara M. Cannon
,
Maria R. Dauvermann
·
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.2147/ndt.s285540
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.2147/ndt.s285540
Childhood trauma (CT) has been repeatedly linked to earlier onset and greater severity of bipolar disorder (BD) in adulthood. However, such knowledge is mostly based on retrospective and cross-sectional studies in adults with BD. The first objective of this selective review is to characterize the short-term effects of CT in the development of BD by focusing on studies in young people. The second objective is to describe the longer-term consequences of CT by considering studies with adult participants. This review first outlines the most prominent hypotheses linking CT exposure and the onset of BD. Then, it summarizes the psychological and biological risk factors implicated in the development of BD, followed by a discussion of original studies that investigated the role of CT in young people with early-onset BD, youths at increased risk of developing BD, or young people with BD with a focus on subclinical and clinical outcome measures. The review considers additional biological and psychological factors associated with a negative impact of CT on the long-term course of BD in later adulthood. Finally, we discuss how the integration of information of CT can improve ongoing early identification of BD and mitigate severe clinical expression in later adulthood.
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.2147/ndt.s285540
- https://www.dovepress.com/getfile.php?fileID=64733
- OA Status
- gold
- Cited By
- 41
- References
- 179
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3110682266
All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W3110682266Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.2147/ndt.s285540Digital Object Identifier
- Title
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<p>The Impact of Childhood Trauma on Developing Bipolar Disorder: Current Understanding and Ensuring Continued Progress</p>Work title
- Type
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reviewOpenAlex work type
- Language
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enPrimary language
- Publication year
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2020Year of publication
- Publication date
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2020-12-01Full publication date if available
- Authors
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Yann Quidé, Leonardo Tozzi, Mark Corcoran, Dara M. Cannon, Maria R. DauvermannList of authors in order
- Landing page
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https://doi.org/10.2147/ndt.s285540Publisher landing page
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https://www.dovepress.com/getfile.php?fileID=64733Direct link to full text PDF
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
- OA URL
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https://www.dovepress.com/getfile.php?fileID=64733Direct OA link when available
- Concepts
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Medicine, Subclinical infection, Bipolar disorder, Young adult, Vulnerability (computing), Early adulthood, Psychiatry, Pediatrics, Clinical psychology, Gerontology, Pathology, Cognition, Computer security, Computer scienceTop concepts (fields/topics) attached by OpenAlex
- Cited by
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41Total citation count in OpenAlex
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2025: 12, 2024: 4, 2023: 10, 2022: 10, 2021: 5Per-year citation counts (last 5 years)
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179Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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